PDB: 339 resultsInfo pagesStatus searchChemie searchBIRD

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4EFX	Highly biologically active insulin with additional disulfide bond Descriptor: Insulin, ZINC ION Authors: Norrman, M, Vinther, T.N. Deposit date: 2012-03-30 Release date: 2013-03-06 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.98 Å) Cite: Insulin analog with additional disulfide bond has increased stability and preserved activity. Protein Sci., 22, 2013
4EUX	Structure of neuronal nitric oxide synthase heme domain in complex with 6-(5-(((3R,4R)-4-((6-amino-4-methylpyridin-2-yl)methyl)pyrrolidin-3-yl)oxy)pentyl)-4-methylpyridin-2-amine Descriptor: 5,6,7,8-TETRAHYDROBIOPTERIN, 6-[5-({(3R,4R)-4-[(6-amino-4-methylpyridin-2-yl)methyl]pyrrolidin-3-yl}oxy)pentyl]-4-methylpyridin-2-amine, ACETATE ION, ... Authors: Li, H, Poulos, T.L. Deposit date: 2012-04-25 Release date: 2012-07-11 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.14 Å) Cite: Selective monocationic inhibitors of neuronal nitric oxide synthase. Binding mode insights from molecular dynamics simulations. J.Am.Chem.Soc., 134, 2012
4EWA	Study on structure and function relationships in human Pirin with Fe ion Descriptor: FE (III) ION, Pirin Authors: Liu, F, Rehmani, I, Chen, L, Fu, R, Serrano, V, Wilson, D.W, Liu, A. Deposit date: 2012-04-26 Release date: 2013-05-29 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.47 Å) Cite: Pirin is an iron-dependent redox regulator of NF-kappa B. Proc.Natl.Acad.Sci.USA, 110, 2013
4F1P	Crystal Structure of mutant S554D for ArfGAP and ANK repeat domain of ACAP1 Descriptor: Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1, SULFATE ION, ... Authors: Sun, F, Pang, X, Zhang, K, Ma, J, Zhou, Q. Deposit date: 2012-05-07 Release date: 2012-07-18 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Mechanistic insights into regulated cargo binding by ACAP1 protein J.Biol.Chem., 287, 2012
4IGN	2.32 Angstrom X-ray Crystal structure of R47A mutant of human ACMSD Descriptor: 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase, ZINC ION Authors: Liu, F, Liu, A. Deposit date: 2012-12-17 Release date: 2014-05-07 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.329 Å) Cite: Human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD): A structural and mechanistic unveiling. Proteins, 83, 2015
4FGU	Crystal structure of prolegumain Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Legumain Authors: Dall, E, Brandstetter, H. Deposit date: 2012-06-05 Release date: 2013-07-03 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (3.9 Å) Cite: Mechanistic and structural studies on legumain explain its zymogenicity, distinct activation pathways, and regulation. Proc.Natl.Acad.Sci.USA, 110, 2013
4J2Q	Crystal structure of C-terminally truncated arrestin reveals mechanism of arrestin activation Descriptor: S-arrestin Authors: Kim, Y.J, Scheerer, P, Choe, H.-W. Deposit date: 2013-02-05 Release date: 2013-05-01 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3 Å) Cite: Crystal structure of pre-activated arrestin p44. Nature, 497, 2013
4JC3	14-3-3 protein interaction with Estrogen Receptor Alpha provides a novel drug target interface Descriptor: 14-3-3 protein sigma, Estrogen receptor Peptide, MAGNESIUM ION Authors: Bier, D, Ottmann, C. Deposit date: 2013-02-21 Release date: 2013-05-15 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Interaction of 14-3-3 proteins with the estrogen receptor alpha F domain provides a drug target interface. Proc. Natl. Acad. Sci. U.S.A., 110, 2013
4F9C	Human CDC7 kinase in complex with DBF4 and XL413 Descriptor: 8-chloro-2-[(2S)-pyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3H)-one, Cell division cycle 7-related protein kinase, Protein DBF4 homolog A, ... Authors: Hughes, S, Cherepanov, P. Deposit date: 2012-05-18 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.08 Å) Cite: Crystal structure of human CDC7 kinase in complex with its activator DBF4. Nat.Struct.Mol.Biol., 19, 2012
4JJ0	Crystal structure of MamP Descriptor: GLYCEROL, HEME C, MamP Authors: Siponen, M, Pignol, D, Arnoux, P. Deposit date: 2013-03-07 Release date: 2013-10-09 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural insight into magnetochrome-mediated magnetite biomineralization. Nature, 502, 2013
4F9B	Human CDC7 kinase in complex with DBF4 and PHA767491 Descriptor: 2-(pyridin-4-yl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one, Cell division cycle 7-related protein kinase, Protein DBF4 homolog A, ... Authors: Hughes, S, Cherepanov, P. Deposit date: 2012-05-18 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structure of human CDC7 kinase in complex with its activator DBF4. Nat.Struct.Mol.Biol., 19, 2012
4FWE	Native structure of LSD2 /AOF1/KDM1b in spacegroup of C2221 at 2.13A Descriptor: CITRATE ANION, FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1B, ... Authors: Zhang, Q, Chen, Z. Deposit date: 2012-07-01 Release date: 2013-01-16 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.13 Å) Cite: Structure-function analysis reveals a novel mechanism for regulation of histone demethylase LSD2/AOF1/KDM1b Cell Res., 23, 2013
4G3D	Crystal structure of human NF-kappaB inducing kinase (NIK) Descriptor: MAGNESIUM ION, NF-kappa-beta-inducing kinase Authors: Hymowitz, S.G, de Leon-Boenig, G. Deposit date: 2012-07-13 Release date: 2012-08-15 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.9 Å) Cite: The crystal structure of the catalytic domain of the NF-kappaB inducing kinase reveals a narrow but flexible active site. Structure, 20, 2012
4JDD	14-3-3 protein interaction with Estrogen Receptor Alpha provides a novel drug target interface Descriptor: 14-3-3 protein sigma, Estrogen receptor Peptide, FUSICOCCIN Authors: Bier, D, Ottmann, C. Deposit date: 2013-02-25 Release date: 2013-05-15 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Interaction of 14-3-3 proteins with the estrogen receptor alpha F domain provides a drug target interface. Proc. Natl. Acad. Sci. U.S.A., 110, 2013
4JJ3	Crystal structure of MamP soaked with iron(II) Descriptor: HEME C, MamP Authors: Siponen, M, Pignol, D, Arnoux, P. Deposit date: 2013-03-07 Release date: 2013-10-09 Last modified: 2024-12-25 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural insight into magnetochrome-mediated magnetite biomineralization. Nature, 502, 2013
4F99	Human CDC7 kinase in complex with DBF4 and nucleotide Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division cycle 7-related protein kinase, MAGNESIUM ION, ... Authors: Hughes, S, Cherepanov, P. Deposit date: 2012-05-18 Release date: 2012-10-31 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.33 Å) Cite: Crystal structure of human CDC7 kinase in complex with its activator DBF4. Nat.Struct.Mol.Biol., 19, 2012
4E04	RpBphP2 chromophore-binding domain crystallized by homologue-directed mutagenesis. Descriptor: 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Bacteriophytochrome (Light-regulated signal transduction histidine kinase), PhyB1 Authors: Bellini, D, Papiz, M.Z. Deposit date: 2012-03-02 Release date: 2012-07-25 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (1.79 Å) Cite: Dimerization properties of the RpBphP2 chromophore-binding domain crystallized by homologue-directed mutagenesis. Acta Crystallogr.,Sect.D, 68, 2012
4DGL	Crystal Structure of the CK2 Tetrameric Holoenzyme Descriptor: Casein kinase II subunit alpha, Casein kinase II subunit beta, ZINC ION Authors: Lolli, G, Battistutta, R. Deposit date: 2012-01-26 Release date: 2012-05-02 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural determinants of protein kinase CK2 regulation by autoinhibitory polymerization. Acs Chem.Biol., 7, 2012
4F9A	Human CDC7 kinase in complex with DBF4 and nucleotide Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division cycle 7-related protein kinase, MAGNESIUM ION, ... Authors: Hughes, S, Cherepanov, P. Deposit date: 2012-05-18 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.17 Å) Cite: Crystal structure of human CDC7 kinase in complex with its activator DBF4. Nat.Struct.Mol.Biol., 19, 2012
4H5C	Crystal structure of human FPPS in ternary complex with YS0470 and inorganic phosphate Descriptor: Farnesyl pyrophosphate synthase, MAGNESIUM ION, PHOSPHATE ION, ... Authors: Park, J, Lin, Y.-S, Tsantrizos, Y.S, Berghuis, A.M. Deposit date: 2012-09-18 Release date: 2012-12-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.02 Å) Cite: Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure. Bmc Struct.Biol., 12, 2012
4LCQ	The crystal structure of di-Zn dihydropyrimidinase in complex with NCBI Descriptor: (2S)-3-(carbamoylamino)-2-methylpropanoic acid, ZINC ION, dihydropyrimidinase Authors: Hsieh, Y.C, Chen, M.C, Hsu, C.C, Chan, S.I, Yang, Y.S, Chen, C.J. Deposit date: 2013-06-22 Release date: 2013-09-18 Last modified: 2025-03-26 Method: X-RAY DIFFRACTION (1.81 Å) Cite: Crystal structures of vertebrate dihydropyrimidinase and complexes from Tetraodon nigroviridis with lysine carbamylation: metal and structural requirements for post-translational modification and function. J.Biol.Chem., 288, 2013
4H5E	Crystal structure of human FPPS in ternary complex with YS0470 and isopentenyl pyrophosphate Descriptor: Farnesyl pyrophosphate synthase, ISOPENTYL PYROPHOSPHATE, MAGNESIUM ION, ... Authors: Park, J, Lin, Y.-S, Tsantrizos, Y.S, Berghuis, A.M. Deposit date: 2012-09-18 Release date: 2012-12-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.04 Å) Cite: Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure. Bmc Struct.Biol., 12, 2012
4G3C	Crystal structure of apo murine Nf-kappaB inducing kinase (NIK) Descriptor: NF-kappa-beta-inducing kinase, SULFATE ION Authors: Hymowitz, S.G, de Leon-Boenig, G. Deposit date: 2012-07-13 Release date: 2012-08-08 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.15 Å) Cite: The crystal structure of the catalytic domain of the NF-kappaB inducing kinase reveals a narrow but flexible active site. Structure, 20, 2012
4LCS	The crystal structure of di-Zn dihydropyrimidinase in complex with hydantoin Descriptor: Chromosome 8 SCAF14545, whole genome shotgun sequence, ZINC ION, ... Authors: Hsieh, Y.C, Chen, M.C, Hsu, C.C, Chan, S.I, Yang, Y.S. Deposit date: 2013-06-23 Release date: 2013-09-18 Last modified: 2025-03-26 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structures of vertebrate dihydropyrimidinase and complexes from Tetraodon nigroviridis with lysine carbamylation: metal and structural requirements for post-translational modification and function. J.Biol.Chem., 288, 2013
4I1Q	Crystal Structure of hBRAP1 N-BAR domain Descriptor: Bridging integrator 2 Authors: Sanchez-Barrena, M.J. Deposit date: 2012-11-21 Release date: 2013-02-06 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.53 Å) Cite: Bin2 Is a Membrane Sculpting N-BAR Protein That Influences Leucocyte Podosomes, Motility and Phagocytosis Plos One, 7, 2012

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