PDB: 326 resultsInfo pagesStatus searchChemie searchBIRD

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4GA7	Crystal structure of human serpinB1 mutant Descriptor: Leukocyte elastase inhibitor Authors: Wang, L, Li, Q, Wu, L, Zhang, K, Tong, L, Sun, F, Fan, Z. Deposit date: 2012-07-25 Release date: 2013-01-16 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Identification of SERPINB1 as a physiological inhibitor of human granzyme H J.Immunol., 190, 2013
4FWE	Native structure of LSD2 /AOF1/KDM1b in spacegroup of C2221 at 2.13A Descriptor: CITRATE ANION, FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1B, ... Authors: Zhang, Q, Chen, Z. Deposit date: 2012-07-01 Release date: 2013-01-16 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.13 Å) Cite: Structure-function analysis reveals a novel mechanism for regulation of histone demethylase LSD2/AOF1/KDM1b Cell Res., 23, 2013
4G3D	Crystal structure of human NF-kappaB inducing kinase (NIK) Descriptor: MAGNESIUM ION, NF-kappa-beta-inducing kinase Authors: Hymowitz, S.G, de Leon-Boenig, G. Deposit date: 2012-07-13 Release date: 2012-08-15 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.9 Å) Cite: The crystal structure of the catalytic domain of the NF-kappaB inducing kinase reveals a narrow but flexible active site. Structure, 20, 2012
4DGL	Crystal Structure of the CK2 Tetrameric Holoenzyme Descriptor: Casein kinase II subunit alpha, Casein kinase II subunit beta, ZINC ION Authors: Lolli, G, Battistutta, R. Deposit date: 2012-01-26 Release date: 2012-05-02 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural determinants of protein kinase CK2 regulation by autoinhibitory polymerization. Acs Chem.Biol., 7, 2012
4F99	Human CDC7 kinase in complex with DBF4 and nucleotide Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division cycle 7-related protein kinase, MAGNESIUM ION, ... Authors: Hughes, S, Cherepanov, P. Deposit date: 2012-05-18 Release date: 2012-10-31 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.33 Å) Cite: Crystal structure of human CDC7 kinase in complex with its activator DBF4. Nat.Struct.Mol.Biol., 19, 2012
4F9B	Human CDC7 kinase in complex with DBF4 and PHA767491 Descriptor: 2-(pyridin-4-yl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one, Cell division cycle 7-related protein kinase, Protein DBF4 homolog A, ... Authors: Hughes, S, Cherepanov, P. Deposit date: 2012-05-18 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structure of human CDC7 kinase in complex with its activator DBF4. Nat.Struct.Mol.Biol., 19, 2012
4F9C	Human CDC7 kinase in complex with DBF4 and XL413 Descriptor: 8-chloro-2-[(2S)-pyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3H)-one, Cell division cycle 7-related protein kinase, Protein DBF4 homolog A, ... Authors: Hughes, S, Cherepanov, P. Deposit date: 2012-05-18 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.08 Å) Cite: Crystal structure of human CDC7 kinase in complex with its activator DBF4. Nat.Struct.Mol.Biol., 19, 2012
4FWF	Complex structure of LSD2/AOF1/KDM1b with H3K4 mimic Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Histone H3.1, Lysine-specific histone demethylase 1B, ... Authors: Zhang, Q, Chen, Z. Deposit date: 2012-07-01 Release date: 2013-01-16 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structure-function analysis reveals a novel mechanism for regulation of histone demethylase LSD2/AOF1/KDM1b Cell Res., 23, 2013
4G3C	Crystal structure of apo murine Nf-kappaB inducing kinase (NIK) Descriptor: NF-kappa-beta-inducing kinase, SULFATE ION Authors: Hymowitz, S.G, de Leon-Boenig, G. Deposit date: 2012-07-13 Release date: 2012-08-08 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.15 Å) Cite: The crystal structure of the catalytic domain of the NF-kappaB inducing kinase reveals a narrow but flexible active site. Structure, 20, 2012
4H5C	Crystal structure of human FPPS in ternary complex with YS0470 and inorganic phosphate Descriptor: Farnesyl pyrophosphate synthase, MAGNESIUM ION, PHOSPHATE ION, ... Authors: Park, J, Lin, Y.-S, Tsantrizos, Y.S, Berghuis, A.M. Deposit date: 2012-09-18 Release date: 2012-12-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.02 Å) Cite: Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure. Bmc Struct.Biol., 12, 2012
4H5E	Crystal structure of human FPPS in ternary complex with YS0470 and isopentenyl pyrophosphate Descriptor: Farnesyl pyrophosphate synthase, ISOPENTYL PYROPHOSPHATE, MAGNESIUM ION, ... Authors: Park, J, Lin, Y.-S, Tsantrizos, Y.S, Berghuis, A.M. Deposit date: 2012-09-18 Release date: 2012-12-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.04 Å) Cite: Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure. Bmc Struct.Biol., 12, 2012
4GOB	Low pH Crystal Structure of a reconstructed Kaede-type Red Fluorescent Protein, Least Evolved Ancestor (LEA) Descriptor: Kaede-type Fluorescent Protein Authors: Kim, H, Grunkemeyer, T.J, Chen, L, Fromme, R, Wachter, R.M. Deposit date: 2012-08-19 Release date: 2013-07-31 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.53 Å) Cite: Acid-base catalysis and crystal structures of a least evolved ancestral GFP-like protein undergoing green-to-red photoconversion. Biochemistry, 52, 2013
4GPZ	Crystal structure of human B type phosphoglycerate mutase H11 phosphorylated form Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Phosphoglycerate mutase 1 Authors: He, C, Zhou, L, Zhang, L. Deposit date: 2012-08-22 Release date: 2013-05-22 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation. Nat Commun, 4, 2013
4EFX	Highly biologically active insulin with additional disulfide bond Descriptor: Insulin, ZINC ION Authors: Norrman, M, Vinther, T.N. Deposit date: 2012-03-30 Release date: 2013-03-06 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.98 Å) Cite: Insulin analog with additional disulfide bond has increased stability and preserved activity. Protein Sci., 22, 2013
4H5D	Crystal structure of human FPPS in ternary complex with YS0470 and inorganic pyrophosphate Descriptor: Farnesyl pyrophosphate synthase, MAGNESIUM ION, PYROPHOSPHATE 2-, ... Authors: Park, J, Lin, Y.-S, Tsantrizos, Y.S, Berghuis, A.M. Deposit date: 2012-09-18 Release date: 2012-12-26 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.02 Å) Cite: Ternary complex structures of human farnesyl pyrophosphate synthase bound with a novel inhibitor and secondary ligands provide insights into the molecular details of the enzyme's active site closure. Bmc Struct.Biol., 12, 2012
4F9A	Human CDC7 kinase in complex with DBF4 and nucleotide Descriptor: ADENOSINE-5'-DIPHOSPHATE, Cell division cycle 7-related protein kinase, MAGNESIUM ION, ... Authors: Hughes, S, Cherepanov, P. Deposit date: 2012-05-18 Release date: 2012-10-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.17 Å) Cite: Crystal structure of human CDC7 kinase in complex with its activator DBF4. Nat.Struct.Mol.Biol., 19, 2012
4E04	RpBphP2 chromophore-binding domain crystallized by homologue-directed mutagenesis. Descriptor: 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium-2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, Bacteriophytochrome (Light-regulated signal transduction histidine kinase), PhyB1 Authors: Bellini, D, Papiz, M.Z. Deposit date: 2012-03-02 Release date: 2012-07-25 Last modified: 2013-01-23 Method: X-RAY DIFFRACTION (1.79 Å) Cite: Dimerization properties of the RpBphP2 chromophore-binding domain crystallized by homologue-directed mutagenesis. Acta Crystallogr.,Sect.D, 68, 2012
4HLY	The complex crystal structure of the DNA binding domain of vIRF-1 from the oncogenic KSHV with DNA Descriptor: 5'-D(*GP*CP*GP*TP*CP*GP*AP*GP*AP*CP*GP*C)-3', K9 Authors: Hew, K, Venkatachalam, R. Deposit date: 2012-10-17 Release date: 2013-03-13 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.48 Å) Cite: The crystal structure of the DNA-binding domain of vIRF-1 from the oncogenic KSHV reveals a conserved fold for DNA binding and reinforces its role as a transcription factor. Nucleic Acids Res., 41, 2013
4HPH	The crystal structure of isomaltulose synthase mutant E295Q from Erwinia rhapontici NX5 in complex with its natural substrate sucrose Descriptor: CALCIUM ION, GLYCEROL, Sucrose isomerase, ... Authors: Xu, Z, Li, S, Xu, H, Zhou, J. Deposit date: 2012-10-23 Release date: 2013-10-16 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.7 Å) Cite: The Structural Basis of Erwinia rhapontici Isomaltulose Synthase Plos One, 8, 2013
4HOW	The crystal structure of isomaltulose synthase from Erwinia rhapontici NX5 Descriptor: CALCIUM ION, GLYCEROL, Sucrose isomerase Authors: Xu, Z, Li, S, Xu, H, Zhou, J. Deposit date: 2012-10-22 Release date: 2013-10-16 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.7 Å) Cite: The Structural Basis of Erwinia rhapontici Isomaltulose Synthase Plos One, 8, 2013
4HOZ	The crystal structure of isomaltulose synthase mutant D241A from Erwinia rhapontici NX5 in complex with D-glucose Descriptor: CALCIUM ION, GLYCEROL, Sucrose isomerase, ... Authors: Xu, Z, Li, S, Xu, H, Zhou, J. Deposit date: 2012-10-23 Release date: 2013-10-16 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2 Å) Cite: The Structural Basis of Erwinia rhapontici Isomaltulose Synthase Plos One, 8, 2013
4J2Q	Crystal structure of C-terminally truncated arrestin reveals mechanism of arrestin activation Descriptor: S-arrestin Authors: Kim, Y.J, Scheerer, P, Choe, H.-W. Deposit date: 2013-02-05 Release date: 2013-05-01 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3 Å) Cite: Crystal structure of pre-activated arrestin p44. Nature, 497, 2013
4JJ0	Crystal structure of MamP Descriptor: GLYCEROL, HEME C, MamP Authors: Siponen, M, Pignol, D, Arnoux, P. Deposit date: 2013-03-07 Release date: 2013-10-09 Last modified: 2013-11-13 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural insight into magnetochrome-mediated magnetite biomineralization. Nature, 502, 2013
4IGN	2.32 Angstrom X-ray Crystal structure of R47A mutant of human ACMSD Descriptor: 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase, ZINC ION Authors: Liu, F, Liu, A. Deposit date: 2012-12-17 Release date: 2014-05-07 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.329 Å) Cite: Human alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase (ACMSD): A structural and mechanistic unveiling. Proteins, 83, 2015
4JDD	14-3-3 protein interaction with Estrogen Receptor Alpha provides a novel drug target interface Descriptor: 14-3-3 protein sigma, Estrogen receptor Peptide, FUSICOCCIN Authors: Bier, D, Ottmann, C. Deposit date: 2013-02-25 Release date: 2013-05-15 Last modified: 2017-06-07 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Interaction of 14-3-3 proteins with the estrogen receptor alpha F domain provides a drug target interface. Proc. Natl. Acad. Sci. U.S.A., 110, 2013

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