9IIY
 
 | | Cryo-EM Structure of EfPiwi-piRNA-target (25-nt, bilobed) | | Descriptor: | Piwi, RNA (5'-R(P*CP*GP*UP*CP*UP*AP*UP*AP*CP*AP*AP*CP*CP*GP*AP*UP*CP*AP*GP*CP*U)-3'), RNA (5'-R(P*UP*AP*GP*CP*AP*GP*AP*UP*CP*GP*GP*UP*UP*GP*UP*AP*UP*AP*GP*AP*CP*G)-3') | | Authors: | Li, Z.Q, Xu, Q.K, Wu, J.P, Shen, E.Z. | | Deposit date: | 2024-06-21 | | Release date: | 2024-11-13 | | Last modified: | 2025-07-23 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural insights into RNA cleavage by PIWI Argonaute.
Nature, 639, 2025
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9IIZ
 | | Cryo-EM Structure of EfPiwi-piRNA-target (25-nt, comma) | | Descriptor: | Piwi, RNA (25-MER), RNA (5'-R(P*AP*GP*CP*CP*AP*AP*GP*UP*UP*UP*CP*CP*AP*UP*GP*UP*UP*GP*AP*UP*GP*GP*UP*A)-3') | | Authors: | Li, Z.Q, Xu, Q.K, Wu, J.P, Shen, E.Z. | | Deposit date: | 2024-06-21 | | Release date: | 2024-11-13 | | Last modified: | 2025-07-16 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structural insights into RNA cleavage by PIWI Argonaute.
Nature, 639, 2025
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9IJ1
 | | Cryo-EM Structure of MILI-piRNA-target (22-nt, bilobed) | | Descriptor: | MAGNESIUM ION, Piwi-like protein 2, RNA (26-MER), ... | | Authors: | Li, Z.Q, Xu, Q.K, Wu, J.P, Shen, E.Z. | | Deposit date: | 2024-06-21 | | Release date: | 2024-11-13 | | Last modified: | 2025-07-16 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural insights into RNA cleavage by PIWI Argonaute.
Nature, 639, 2025
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9IJ3
 | | Cryo-EM Structure of MILI-piRNA-target (26-nt) | | Descriptor: | MANGANESE (II) ION, Piwi-like protein 2, RNA (25-MER), ... | | Authors: | Li, Z.Q, Xu, Q.K, Wu, J.P, Shen, E.Z. | | Deposit date: | 2024-06-21 | | Release date: | 2024-11-13 | | Last modified: | 2025-07-23 | | Method: | ELECTRON MICROSCOPY (2.6 Å) | | Cite: | Structural insights into RNA cleavage by PIWI Argonaute.
Nature, 639, 2025
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9IJ2
 | | Cryo-EM Structure of MILI-piRNA-target (22-nt, comma) | | Descriptor: | Piwi-like protein 2, RNA (5'-R(P*CP*AP*AP*GP*UP*UP*UP*CP*CP*AP*UP*GP*UP*UP*GP*AP*UP*GP*GP*UP*A)-3'), RNA (5'-R(P*UP*UP*AP*CP*CP*AP*UP*CP*AP*AP*CP*AP*UP*GP*GP*AP*AP*AP*CP*UP*UP*G)-3') | | Authors: | Li, Z.Q, Xu, Q.K, Wu, J.P, Shen, E.Z. | | Deposit date: | 2024-06-21 | | Release date: | 2024-11-13 | | Last modified: | 2025-07-16 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structural insights into RNA cleavage by PIWI Argonaute.
Nature, 639, 2025
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4C16
 | | E-selectin lectin, EGF-like and two SCR domains complexed with glycomimetic antagonist | | Descriptor: | (1R,2R,3S)-3-methylcyclohexane-1,2-diol, (S)-CYCLOHEXYL LACTIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Preston, R.C, Jakob, R.P, Binder, F.P.C, Sager, C.P, Ernst, B, Maier, T. | | Deposit date: | 2013-08-09 | | Release date: | 2014-08-20 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | E-Selectin Ligand Complexes Adopt an Extended High-Affinity Conformation.
J.Mol.Cell.Biol., 8, 2016
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2O72
 | | Crystal Structure Analysis of human E-cadherin (1-213) | | Descriptor: | CALCIUM ION, Epithelial-cadherin | | Authors: | Parisini, E, Wang, J.-H. | | Deposit date: | 2006-12-09 | | Release date: | 2007-10-09 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The Crystal Structure of Human E-cadherin Domains 1 and 2, and Comparison with other Cadherins in the Context of Adhesion Mechanism
J.Mol.Biol., 373, 2007
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2GNN
 | | Crystal Structure of the Orf Virus NZ2 Variant of VEGF-E | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, BENZAMIDINE, ... | | Authors: | Prota, A.E, Pieren, M, Wagner, A, Kostrewa, D, Winkler, F.K, Ballmer-Hofer, K. | | Deposit date: | 2006-04-10 | | Release date: | 2006-05-09 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of the Orf virus NZ2 variant of vascular endothelial growth factor-E. Implications for receptor specificity.
J.Biol.Chem., 281, 2006
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7YG6
 | | Cryo-EM structure of the EfPiwi(N959K) in complex with piRNA | | Descriptor: | MAGNESIUM ION, Piwi, piRNA | | Authors: | Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. | | Deposit date: | 2022-07-11 | | Release date: | 2024-01-24 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.
Nat.Struct.Mol.Biol., 2024
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7YFX
 | | Cryo-EM structure of Hili in complex with piRNA | | Descriptor: | MAGNESIUM ION, Piwi-like protein 2, piRNA | | Authors: | Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. | | Deposit date: | 2022-07-09 | | Release date: | 2024-01-24 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.
Nat.Struct.Mol.Biol., 2024
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7YGN
 | | Cryo-EM structure of the Mili in complex with piRNA | | Descriptor: | MAGNESIUM ION, Piwi-like protein 2, piRNA | | Authors: | Li, Z.Q, Liu, H.B, Wu, J.P, Shen, E.Z. | | Deposit date: | 2022-07-11 | | Release date: | 2024-01-24 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Mammalian PIWI-piRNA-target complexes reveal features for broad and efficient target silencing.
Nat.Struct.Mol.Biol., 2024
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4L1T
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4U7Y
 | | Structure of the complex of VPS4B MIT and IST1 MIM | | Descriptor: | IST1 homolog, Vacuolar protein sorting-associated protein 4B | | Authors: | Guo, E.Z, Xu, Z. | | Deposit date: | 2014-07-31 | | Release date: | 2015-02-11 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.502 Å) | | Cite: | Distinct Mechanisms of Recognizing Endosomal Sorting Complex Required for Transport III (ESCRT-III) Protein IST1 by Different Microtubule Interacting and Trafficking (MIT) Domains.
J.Biol.Chem., 290, 2015
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4U7I
 | | Structure of the complex of Spartin MIT and IST1 MIM | | Descriptor: | IST1 homolog, Spartin | | Authors: | Guo, E.Z, Xu, Z. | | Deposit date: | 2014-07-30 | | Release date: | 2015-02-11 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.794 Å) | | Cite: | Distinct Mechanisms of Recognizing Endosomal Sorting Complex Required for Transport III (ESCRT-III) Protein IST1 by Different Microtubule Interacting and Trafficking (MIT) Domains.
J.Biol.Chem., 290, 2015
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4U7E
 | | The crystal structure of the complex of LIP5 NTD and IST1 MIM | | Descriptor: | IST1 homolog, Vacuolar protein sorting-associated protein VTA1 homolog | | Authors: | Guo, E.Z, Xu, Z. | | Deposit date: | 2014-07-30 | | Release date: | 2015-02-11 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Distinct Mechanisms of Recognizing Endosomal Sorting Complex Required for Transport III (ESCRT-III) Protein IST1 by Different Microtubule Interacting and Trafficking (MIT) Domains.
J.Biol.Chem., 290, 2015
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1EZZ
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4HR7
 | | Crystal Structure of Biotin Carboxyl Carrier Protein-Biotin Carboxylase Complex from E.coli | | Descriptor: | 1,2-ETHANEDIOL, Biotin carboxyl carrier protein of acetyl-CoA carboxylase, Biotin carboxylase, ... | | Authors: | Broussard, T.C, Kobe, M.J, Pakhomova, S, Neau, D.B, Price, A.E, Champion, T.S, Waldrop, G.L. | | Deposit date: | 2012-10-26 | | Release date: | 2013-03-13 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.495 Å) | | Cite: | The three-dimensional structure of the biotin carboxylase-biotin carboxyl carrier protein complex of E. coli acetyl-CoA carboxylase.
Structure, 21, 2013
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2D22
 | | Crystal structure of covalent glycosyl-enzyme intermediate of catalytic-site mutant xylanase from Streptomyces olivaceoviridis E-86 | | Descriptor: | ENDO-1,4-BETA-D-XYLANASE, GLYCEROL, SULFATE ION, ... | | Authors: | Suzuki, R, Kuno, A, Fujimoto, Z, Ito, S, Kawahara, S.I, Kaneko, S, Hasegawa, T, Taira, K. | | Deposit date: | 2005-09-02 | | Release date: | 2006-10-10 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystallographic snapshots of an entire reaction cycle for a retaining xylanase from Streptomyces olivaceoviridis E-86
J.Biochem., 146, 2009
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2D1Z
 | | Crystal structure of catalytic-site mutant xylanase from Streptomyces olivaceoviridis E-86 | | Descriptor: | ENDO-1,4-BETA-D-XYLANASE, GLYCEROL, SULFATE ION | | Authors: | Suzuki, R, Kuno, A, Fujimoto, Z, Ito, S, Kawahara, S.I, Kaneko, S, Hasegawa, T, Taira, K. | | Deposit date: | 2005-09-02 | | Release date: | 2006-10-10 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Crystallographic snapshots of an entire reaction cycle for a retaining xylanase from Streptomyces olivaceoviridis E-86
J.Biochem., 146, 2009
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2D20
 | | Crystal structure of michaelis complex of catalytic-site mutant xylanase from Streptomyces olivaceoviridis E-86 | | Descriptor: | ENDO-1,4-BETA-D-XYLANASE, GLYCEROL, P-NITROPHENOL, ... | | Authors: | Suzuki, R, Kuno, A, Fujimoto, Z, Ito, S, Kawahara, S.I, Kaneko, S, Hasegawa, T, Taira, K. | | Deposit date: | 2005-09-02 | | Release date: | 2006-10-10 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Crystallographic snapshots of an entire reaction cycle for a retaining xylanase from Streptomyces olivaceoviridis E-86
J.Biochem., 146, 2009
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2D23
 | | Crystal structure of EP complex of catalytic-site mutant xylanase from Streptomyces olivaceoviridis E-86 | | Descriptor: | AZIDE ION, ENDO-1,4-BETA-D-XYLANASE, GLYCEROL, ... | | Authors: | Suzuki, R, Kuno, A, Fujimoto, Z, Ito, S, Kawahara, S.I, Kaneko, S, Hasegawa, T, Taira, K. | | Deposit date: | 2005-09-02 | | Release date: | 2006-10-10 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Crystallographic snapshots of an entire reaction cycle for a retaining xylanase from Streptomyces olivaceoviridis E-86
J.Biochem., 146, 2009
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1V6X
 | | Crystal Structure Of Xylanase From Streptomyces Olivaceoviridis E-86 Complexed With 3(3)-4-O-methyl-alpha-D-glucuronosyl-xylotriose | | Descriptor: | 4-O-methyl-alpha-D-glucopyranuronic acid-(1-2)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, ENDO-1,4-BETA-D-XYLANASE, beta-D-xylopyranose, ... | | Authors: | Fujimoto, Z, Kaneko, S, Kuno, A, Kobayashi, H, Kusakabe, I, Mizuno, H. | | Deposit date: | 2003-12-04 | | Release date: | 2004-04-27 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structures of decorated xylooligosaccharides bound to a family 10 xylanase from Streptomyces olivaceoviridis E-86
J.Biol.Chem., 279, 2004
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1V6U
 | | Crystal Structure Of Xylanase From Streptomyces Olivaceoviridis E-86 Complexed With 2(2)-alpha-L-arabinofuranosyl-xylobiose | | Descriptor: | alpha-D-xylopyranose, alpha-L-arabinofuranose-(1-3)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose, beta-D-xylopyranose, ... | | Authors: | Fujimoto, Z, Kaneko, S, Kuno, A, Kobayashi, H, Kusakabe, I, Mizuno, H. | | Deposit date: | 2003-12-04 | | Release date: | 2004-04-27 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structures of decorated xylooligosaccharides bound to a family 10 xylanase from Streptomyces olivaceoviridis E-86
J.Biol.Chem., 279, 2004
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1V6Y
 | | Crystal Structure Of chimeric Xylanase between Streptomyces Olivaceoviridis E-86 FXYN and Cellulomonas fimi Cex | | Descriptor: | Beta-xylanase,Exoglucanase/xylanase | | Authors: | Kaneko, S, Ichinose, H, Fujimoto, Z, Kuno, A, Yura, K, Go, M, Mizuno, H, Kusakabe, I, Kobayashi, H. | | Deposit date: | 2003-12-04 | | Release date: | 2004-09-07 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure and function of a family 10 beta-xylanase chimera of Streptomyces olivaceoviridis E-86 FXYN and Cellulomonas fimi Cex
J.Biol.Chem., 279, 2004
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7JGJ
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