2FUF
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2IPR
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3QK2
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2ITL
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3QN2
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5D9I
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![BU of 5d9i by Molmil](/molmil-images/mine/5d9i) | SV40 Large T antigen origin binding domain bound to artificial DNA fork | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... | Authors: | Meinke, G, Bohm, A, Bullock, P.A. | Deposit date: | 2015-08-18 | Release date: | 2015-09-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structure-based analysis of the interaction between the simian virus 40 T-antigen origin binding domain and single-stranded DNA. J. Virol., 85, 2011
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4RXH
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1SVM
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![BU of 1svm by Molmil](/molmil-images/mine/1svm) | Co-crystal structure of SV40 large T antigen helicase domain and ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ZINC ION, ... | Authors: | Gai, D, Zhao, R, Finkielstein, C.V, Chen, X.S. | Deposit date: | 2004-03-29 | Release date: | 2004-10-19 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Mechanisms of conformational change for a replicative hexameric helicase of SV40 large tumor antigen. Cell(Cambridge,Mass.), 119, 2004
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1SVL
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![BU of 1svl by Molmil](/molmil-images/mine/1svl) | Co-crystal structure of SV40 large T antigen helicase domain and ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ZINC ION, ... | Authors: | Gai, D, Zhao, R, Finkielstein, C.V, Chen, X.S. | Deposit date: | 2004-03-29 | Release date: | 2004-10-19 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Mechanisms of conformational change for a replicative hexameric helicase of SV40 large tumor antigen. Cell(Cambridge,Mass.), 119, 2004
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1Q1S
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![BU of 1q1s by Molmil](/molmil-images/mine/1q1s) | Mouse Importin alpha- phosphorylated SV40 CN peptide complex | Descriptor: | Importin alpha-2 subunit, Large T antigen | Authors: | Fontes, M.R.M, Teh, T, Toth, G, John, A, Pavo, I, Jans, D.A, Kobe, B. | Deposit date: | 2003-07-22 | Release date: | 2004-03-30 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha Biochem.J., 375, 2003
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2NL8
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2NTC
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2ITJ
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1Q1T
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![BU of 1q1t by Molmil](/molmil-images/mine/1q1t) | Mouse Importin alpha: non-phosphorylated SV40 CN peptide complex | Descriptor: | Importin alpha-2 subunit, Large T antigen | Authors: | Fontes, M.R.M, Teh, T, Toth, G, John, A, Pavo, I, Jans, D.A, Kobe, B. | Deposit date: | 2003-07-22 | Release date: | 2004-03-30 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha Biochem.J., 375, 2003
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2IF9
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1SVO
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![BU of 1svo by Molmil](/molmil-images/mine/1svo) | Structure of SV40 large T antigen helicase domain | Descriptor: | ZINC ION, large T antigen | Authors: | Gai, D, Zhao, R, Finkielstein, C.V, Chen, X.S. | Deposit date: | 2004-03-29 | Release date: | 2004-10-19 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Mechanisms of conformational change for a replicative hexameric helicase of SV40 large tumor antigen. Cell(Cambridge,Mass.), 119, 2004
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4GDF
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![BU of 4gdf by Molmil](/molmil-images/mine/4gdf) | A Crystal Structure of SV40 Large T Antigen | Descriptor: | DNA (32-MER), Large T antigen, ZINC ION | Authors: | Chang, Y.P, Xu, M, Chen, X.S. | Deposit date: | 2012-07-31 | Release date: | 2013-04-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Mechanism of Origin DNA Recognition and Assembly of an Initiator-Helicase Complex by SV40 Large Tumor Antigen. Cell Rep, 3, 2013
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1N25
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![BU of 1n25 by Molmil](/molmil-images/mine/1n25) | Crystal structure of the SV40 Large T antigen helicase domain | Descriptor: | Large T Antigen, ZINC ION | Authors: | Li, D, Zhao, R, Lilyestrom, W, Gai, D, Zhang, R, DeCaprio, J.A, Fanning, E, Jochimiak, A, Szakonyi, G, Chen, X.S. | Deposit date: | 2002-10-21 | Release date: | 2003-06-03 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of the replicative helicase of the oncoprotein SV40 large tumour antigen Nature, 423, 2003
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1EJL
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2H1L
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4FGN
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1GH6
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![BU of 1gh6 by Molmil](/molmil-images/mine/1gh6) | RETINOBLASTOMA POCKET COMPLEXED WITH SV40 LARGE T ANTIGEN | Descriptor: | Large T antigen, Retinoblastoma-associated protein | Authors: | Kim, H.Y, Cho, Y. | Deposit date: | 2000-11-15 | Release date: | 2001-11-15 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for the inactivation of retinoblastoma tumor suppressor by SV40 large T antigen. EMBO J., 20, 2001
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4E2I
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![BU of 4e2i by Molmil](/molmil-images/mine/4e2i) | The Complex Structure of the SV40 Helicase Large T Antigen and p68 Subunit of DNA Polymerase Alpha-Primase | Descriptor: | DNA polymerase alpha subunit B, Large T antigen, ZINC ION | Authors: | Zhou, B, Arnett, D.R, Yu, X, Brewster, A, Sowd, G.A, Xie, C.L, Vila, S, Gai, D, Fanning, E, Chen, X.S. | Deposit date: | 2012-03-08 | Release date: | 2012-06-13 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (5 Å) | Cite: | Structural basis for the interaction of a hexameric replicative helicase with the regulatory subunit of human DNA polymerase alpha-primase. J.Biol.Chem., 287, 2012
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2TBD
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![BU of 2tbd by Molmil](/molmil-images/mine/2tbd) | SV40 T ANTIGEN DNA-BINDING DOMAIN, NMR, 30 STRUCTURES | Descriptor: | SV40 T ANTIGEN | Authors: | Luo, X, Sanford, D.G, Bullock, P.A, Bachovchin, W.W. | Deposit date: | 1997-01-09 | Release date: | 1997-04-01 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the origin DNA-binding domain of SV40 T-antigen. Nat.Struct.Biol., 3, 1996
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1Z1D
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![BU of 1z1d by Molmil](/molmil-images/mine/1z1d) | Structural Model for the interaction between RPA32 C-terminal domain and SV40 T antigen origin binding domain. | Descriptor: | Large T antigen, Replication protein A 32 kDa subunit | Authors: | Arunkumar, A.I, Klimovich, V, Jiang, X, Ott, R.D, Mizoue, L, Fanning, E, Chazin, W.J. | Deposit date: | 2005-03-03 | Release date: | 2005-05-17 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Insights into hRPA32 C-terminal domain--mediated assembly of the simian virus 40 replisome. Nat.Struct.Mol.Biol., 12, 2005
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