7LNS
 
 | | NMR solution structure of PsDef2 defensin from P. sylvestris | | Descriptor: | Defensin-2 | | Authors: | Nesmelova, I.V, Kovaleva, V, Hrunyk, N.I, Yusypovych, Y.M, Shalovylo, Y.I. | | Deposit date: | 2021-02-08 | | Release date: | 2022-03-30 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Structure, dynamics, and function of PsDef2 defensin from Pinus sylvestris.
Structure, 30, 2022
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6LCQ
 | | Crystal structure of rice defensin OsAFP1 | | Descriptor: | Defensin-like protein CAL1, PHOSPHATE ION | | Authors: | Ochiai, A, Ogawa, K, Fukuda, M, Suzuki, M, Ito, K, Tanaka, T, Sagehashi, Y, Taniguchi, M. | | Deposit date: | 2019-11-19 | | Release date: | 2020-04-01 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.62 Å) | | Cite: | Crystal structure of rice defensin OsAFP1 and molecular insight into lipid-binding.
J.Biosci.Bioeng., 130, 2020
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8GXT
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5NCE
 | | Structure of PsDef1 defensin from Pinus sylvestris | | Descriptor: | Defensin-1 | | Authors: | Khairutdinov, B.I, Ermakova, E.A, Bessolitsyna, E.K, Toporkova, Y.Y, Tarasova, N.B, Kovaleva, V, Zuev, Y.F, Nesmelova, I.V. | | Deposit date: | 2017-03-03 | | Release date: | 2017-06-07 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | NMR structure, conformational dynamics, and biological activity of PsDef1 defensin from Pinus sylvestris.
Biochim. Biophys. Acta, 1865, 2017
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3PSM
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2GL1
 | | NMR solution structure of Vigna radiata Defensin 2 (VrD2) | | Descriptor: | PDF1 | | Authors: | Lin, K.F, Lee, T.R, Tsai, P.H, Hsu, M.P, Chen, C.S, Lyu, P.C. | | Deposit date: | 2006-04-04 | | Release date: | 2007-04-03 | | Last modified: | 2022-03-09 | | Method: | SOLUTION NMR | | Cite: | Structure-based protein engineering for alpha-amylase inhibitory activity of plant defensin.
Proteins, 68, 2007
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4UJ0
 | | Crystal structure of the tomato defensin TPP3 | | Descriptor: | ACETATE ION, FLOWER-SPECIFIC GAMMA-THIONIN-LIKE PROTEIN/ACIDIC PROTEIN | | Authors: | Richter, V, Lay, F.T, Hulett, M.D, Kvansakul, M. | | Deposit date: | 2015-04-07 | | Release date: | 2015-04-15 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The Tomato Defensin Tpp3 Binds Phosphatidylinositol (4,5)-Bisphosphate Via a Conserved Dimeric Cationic Grip Conformation to Mediate Cell Lysis.
Mol.Cell.Biol., 35, 2015
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6VPN
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5KK4
 | | Crystal Structure of the Plant Defensin NsD7 bound to Phosphatidic Acid | | Descriptor: | (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, 1,2-ETHANEDIOL, ACETATE ION, ... | | Authors: | Kvansakul, M, Hulett, M.D, Lay, F.T. | | Deposit date: | 2016-06-21 | | Release date: | 2016-10-05 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Binding of phosphatidic acid by NsD7 mediates the formation of helical defensin-lipid oligomeric assemblies and membrane permeabilization.
Proc.Natl.Acad.Sci.USA, 113, 2016
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7C31
 | | Crystal structure of the grapevine defensin VvK1 | | Descriptor: | Knot1 domain-containing protein | | Authors: | Chen, M.W, Chang, S.C, Chandy, K.G, Luo, D. | | Deposit date: | 2020-05-10 | | Release date: | 2020-09-16 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Modulation of Lymphocyte Potassium Channel KV1.3 by Membrane-Penetrating, Joint-Targeting Immunomodulatory Plant Defensin.
Acs Pharmacol Transl Sci, 3, 2020
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5VYP
 | | Crystal structure of the Plant Defensin NsD7 bound to PIP2 | | Descriptor: | Defensin NsD7, GLYCEROL, SULFATE ION, ... | | Authors: | Jarva, M, Lay, F.T, Hulett, M, Kvansakul, M. | | Deposit date: | 2017-05-25 | | Release date: | 2017-08-02 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of the defensin NsD7 in complex with PIP2 reveals that defensin : lipid oligomer topologies are dependent on lipid type.
FEBS Lett., 591, 2017
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1TI5
 | | Solution structure of plant defensin | | Descriptor: | plant defensin | | Authors: | Liu, Y.J, Cheng, C.S, Liu, Y.N, Hsu, M.P, Chen, C.S, Lyu, P.C. | | Deposit date: | 2004-06-02 | | Release date: | 2005-07-26 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the plant defensin VrD1 from mung bean and its possible role in insecticidal activity against bruchids.
Proteins, 63, 2006
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4AB0
 | | X-ray crystal structure of Nicotiana alata defensin NaD1 | | Descriptor: | FLOWER-SPECIFIC DEFENSIN, PHOSPHATE ION | | Authors: | Mills, G.D, Lay, F.T, Hulett, M.D, Kvansakul, M. | | Deposit date: | 2011-12-06 | | Release date: | 2012-04-25 | | Last modified: | 2012-06-20 | | Method: | X-RAY DIFFRACTION (1.636 Å) | | Cite: | Dimerization of Plant Defensin Nad1 Enhances its Antifungal Activity.
J.Biol.Chem., 287, 2012
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1AYJ
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4CQK
 | | Crystal structure of ligand-bound NaD1 | | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, FLOWER-SPECIFIC DEFENSIN, SULFATE ION, ... | | Authors: | Lay, F.T, Mills, G.M, Poon, I.K.H, Baxter, A.A, Hulett, M.D, Kvansakul, M. | | Deposit date: | 2014-02-17 | | Release date: | 2014-04-16 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Phosphoinositide-Mediated Oligomerization of a Defensin Induces Cell Lysis.
Elife, 3, 2014
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6B55
 | | Crystal structure of the Plant Defensin NaD1 complexed with phosphatidic acid | | Descriptor: | 1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHATE, 1,2-ETHANEDIOL, Flower-specific defensin, ... | | Authors: | Jarva, M, Phan, K, Humble, C, Lay, F.T, Hulett, M, Kvansakul, M. | | Deposit date: | 2017-09-28 | | Release date: | 2018-05-23 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | X-ray structure of a carpet-like antimicrobial defensin-phospholipid membrane disruption complex.
Nat Commun, 9, 2018
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6MRY
 | | NoD173 plant defensin | | Descriptor: | 1,2-ETHANEDIOL, 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, CHLORIDE ION, ... | | Authors: | Caria, S, Kvansakul, M. | | Deposit date: | 2018-10-15 | | Release date: | 2019-04-24 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural and functional characterization of the membrane-permeabilizing activity ofNicotiana occidentalisdefensin NoD173 and protein engineering to enhance oncolysis.
Faseb J., 33, 2019
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4AAZ
 | | X-ray structure of Nicotiana alata Defensin 1 NaD1 | | Descriptor: | 1,2-ETHANEDIOL, FLOWER-SPECIFIC DEFENSIN, PHOSPHATE ION | | Authors: | Lay, F.T, Mills, G.D, Hulett, M.D, Kvansakul, M. | | Deposit date: | 2011-12-06 | | Release date: | 2012-04-25 | | Last modified: | 2012-08-08 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Dimerization of Plant Defensin Nad1 Enhances its Antifungal Activity.
J.Biol.Chem., 287, 2012
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6NOM
 | | NMR solution structure of Pisum sativum defensin 2 (Psd2) provides evidence for the presence of hydrophobic surface clusters | | Descriptor: | Defensin-2 | | Authors: | Pinheiro-Aguiar, R, Amaral, V.S.G, Bastos, I, Kurtenbach, E, Almeida, F.C.L. | | Deposit date: | 2019-01-16 | | Release date: | 2019-08-21 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Nuclear magnetic resonance solution structure of Pisum sativum defensin 2 provides evidence for the presence of hydrophobic surface-clusters.
Proteins, 88, 2020
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6DMZ
 | | Solution structure of ZmD32 | | Descriptor: | Flower-specific gamma-thionin | | Authors: | Harvey, P.J, Craik, D.J. | | Deposit date: | 2018-06-05 | | Release date: | 2019-05-15 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Salt-Tolerant Antifungal and Antibacterial Activities of the Corn Defensin ZmD32.
Front Microbiol, 10, 2019
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1BK8
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1GPT
 | | SOLUTION STRUCTURE OF GAMMA 1-H AND GAMMA 1-P THIONINS FROM BARLEY AND WHEAT ENDOSPERM DETERMINED BY 1H-NMR: A STRUCTURAL MOTIF COMMON TO TOXIC ARTHROPOD PROTEINS | | Descriptor: | GAMMA-1-H THIONIN | | Authors: | Bruix, M, Jimenez, M.A, Santoro, J, Gonzalez, C, Colilla, F.J, Mendez, E, Rico, M. | | Deposit date: | 1992-07-29 | | Release date: | 1993-10-31 | | Last modified: | 2017-11-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of gamma 1-H and gamma 1-P thionins from barley and wheat endosperm determined by 1H-NMR: a structural motif common to toxic arthropod proteins.
Biochemistry, 32, 1993
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1JKZ
 | | NMR Solution Structure of Pisum sativum defensin 1 (Psd1) | | Descriptor: | DEFENSE-RELATED PEPTIDE 1 | | Authors: | Almeida, M.S, Cabral, K.M.S, Kurtenbach, E, Almeida, F.C.L, Valente, A.P. | | Deposit date: | 2001-07-13 | | Release date: | 2002-02-06 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Solution structure of Pisum sativum defensin 1 by high resolution NMR: plant defensins, identical backbone with different mechanisms of action.
J.Mol.Biol., 315, 2002
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1N4N
 | | Structure of the Plant Defensin PhD1 from Petunia Hybrida | | Descriptor: | floral defensin-like protein 1 | | Authors: | Janssen, B.J.C, Schirra, H.J, Lay, F.T, Anderson, M.A, Craik, D.J. | | Deposit date: | 2002-11-01 | | Release date: | 2003-11-01 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Structure of Petunia hybrida defensin 1, a novel plant defensin with five disulfide bonds
Biochemistry, 42, 2003
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1GPS
 | | SOLUTION STRUCTURE OF GAMMA 1-H AND GAMMA 1-P THIONINS FROM BARLEY AND WHEAT ENDOSPERM DETERMINED BY 1H-NMR: A STRUCTURAL MOTIF COMMON TO TOXIC ARTHROPOD PROTEINS | | Descriptor: | GAMMA-1-P THIONIN | | Authors: | Bruix, M, Jimenez, M.A, Santoro, J, Gonzalez, C, Colilla, F.J, Mendez, E, Rico, M. | | Deposit date: | 1992-07-29 | | Release date: | 1993-10-31 | | Last modified: | 2017-11-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of gamma 1-H and gamma 1-P thionins from barley and wheat endosperm determined by 1H-NMR: a structural motif common to toxic arthropod proteins.
Biochemistry, 32, 1993
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