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PDB: 2 results

Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor PU-H54
Descriptor:	8-[(2,4-dimethylphenyl)sulfanyl]-3-pent-4-yn-1-yl-3H-purin-6-amine, HSP90AA1 protein
Authors:	Seidler, P.M, Gewirth, D.T.
Deposit date:	2010-07-19
Release date:	2011-10-05
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (1.47 Å)
Cite:	Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2. Nat.Chem.Biol., 9, 2013

Structure of the N-domain of GRP94 bound to the HSP90 inhibitor PU-H54
Descriptor:	8-[(2,4-dimethylphenyl)sulfanyl]-3-pent-4-yn-1-yl-3H-purin-6-amine, Endoplasmin, GLYCEROL, ...
Authors:	Seidler, P.M, Gewirth, D.T.
Deposit date:	2010-07-22
Release date:	2011-10-05
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (2 Å)
Cite:	Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2. Nat.Chem.Biol., 9, 2013