1QMF
 
 | | PENICILLIN-BINDING PROTEIN 2X (PBP-2X) ACYL-ENZYME COMPLEX | | Descriptor: | 2-[CARBOXY-(2-FURAN-2-YL-2-METHOXYIMINO-ACETYLAMINO)-METHYL]-5-METHYL-3,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, CEFUROXIME (OCT-3-ENE FORM), PENICILLIN-BINDING PROTEIN 2X | | Authors: | Gordon, E.J, Mouz, N, Duee, E, Dideberg, O. | | Deposit date: | 1999-09-28 | | Release date: | 2000-05-25 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | The Crystal Structure of the Penicillin Binding Protein 2X from Streptococcus Pneumoniae and its Acyl-Enzyme Form: Implication in Drug Resistance
J.Mol.Biol., 299, 2000
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1QME
 | | PENICILLIN-BINDING PROTEIN 2X (PBP-2X) | | Descriptor: | PENICILLIN-BINDING PROTEIN 2X, SULFATE ION | | Authors: | Gordon, E.J, Mouz, N, Duee, E, Dideberg, O. | | Deposit date: | 1999-09-28 | | Release date: | 2000-05-25 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The Crystal Structure of the Penicillin-Binding Protein 2X from Streptococcus Pneumoniae and its Acyl-Enzyme Form: Implication in Drug Resistance.
J.Mol.Biol., 299, 2000
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1RP5
 | | PBP2x from Streptococcus pneumoniae strain 5259 with reduced susceptibility to beta-lactam antibiotics | | Descriptor: | SULFATE ION, penicillin-binding protein 2x | | Authors: | Pernot, L, Chesnel, L, Legouellec, A, Croize, J, Vernet, T, Dideberg, O, Dessen, A. | | Deposit date: | 2003-12-03 | | Release date: | 2004-02-03 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | A PBP2x from a clinical isolate of Streptococcus pneumoniae exhibits an alternative mechanism for reduction of susceptibility to beta-lactam antibiotics.
J.Biol.Chem., 279, 2004
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1PYY
 | | Double mutant PBP2x T338A/M339F from Streptococcus pneumoniae strain R6 at 2.4 A resolution | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 6-O-octanoyl-beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, Penicillin-binding protein 2X, ... | | Authors: | Chesnel, L, Pernot, L, Lemaire, D, Champelovier, D, Croize, J, Dideberg, O, Vernet, T, Zapun, A. | | Deposit date: | 2003-07-09 | | Release date: | 2003-09-30 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.42 Å) | | Cite: | The Structural Modifications Induced by the M339F Substitution in PBP2x from Streptococcus pneumoniae Further Decreases the Susceptibility to beta-Lactams of Resistant Strains
J.Biol.Chem., 278, 2003
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