7VWO
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7BY2
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7BY3
| Toxin-antitoxin complex from klebsiella pneumoniae | Descriptor: | CopG family transcriptional regulator, Ribonuclease VapC, SULFATE ION | Authors: | Kang, S.M. | Deposit date: | 2020-04-21 | Release date: | 2021-04-28 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Toxin-antitoxin complex from klebsiella pneumoniae To Be Published
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6SD6
| Structure of VapBC from Shigella sonnei | Descriptor: | Antitoxin, tRNA(fMet)-specific endonuclease VapC | Authors: | Lea, S.M, Hollingshead, S. | Deposit date: | 2019-07-26 | Release date: | 2020-08-26 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Polymorphisms in the VapBC toxin:antitoxin system mediate high frequency plasmid loss in Shigella sonnei To Be Published
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6IFM
| Crystal structure of DNA bound VapBC from Salmonella typhimurium | Descriptor: | Antitoxin VapB, DNA backward (27-MER), DNA forward (27-MER), ... | Authors: | Park, D.W, Lee, B.J. | Deposit date: | 2018-09-20 | Release date: | 2020-01-29 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.804 Å) | Cite: | Crystal structure of proteolyzed VapBC and DNA-bound VapBC from Salmonella enterica Typhimurium LT2 and VapC as a putative Ca2+-dependent ribonuclease. Faseb J., 34, 2020
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6IFC
| Crystal structure of VapBC from Salmonella typhimurium | Descriptor: | Antitoxin VapB, CALCIUM ION, tRNA(fMet)-specific endonuclease VapC | Authors: | Park, D.W, Lee, B.J. | Deposit date: | 2018-09-19 | Release date: | 2020-01-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Crystal structure of proteolyzed VapBC and DNA-bound VapBC from Salmonella enterica Typhimurium LT2 and VapC as a putative Ca2+-dependent ribonuclease. Faseb J., 34, 2020
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6NKL
| 2.2 A resolution structure of VapBC-1 from nontypeable Haemophilus influenzae | Descriptor: | Antitoxin VapB1, Ribonuclease VapC | Authors: | Lovell, S, Kashipathy, M.M, Battaile, K.P, Molinaro, A.L, Daines, D.A. | Deposit date: | 2019-01-07 | Release date: | 2019-04-10 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of VapBC-1 from Nontypeable Haemophilus influenzae and the Effect of PIN Domain Mutations on Survival during Infection. J.Bacteriol., 201, 2019
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6A7V
| Crystal structure of Mycobacterium tuberculosis VapBC11 toxin-antitoxin complex | Descriptor: | Antitoxin VapB11, PENTAETHYLENE GLYCOL, Ribonuclease VapC11, ... | Authors: | Deep, A, Thakur, K.G. | Deposit date: | 2018-07-04 | Release date: | 2018-10-10 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Structural, functional and biological insights into the role of Mycobacterium tuberculosis VapBC11 toxin-antitoxin system: targeting a tRNase to tackle mycobacterial adaptation. Nucleic Acids Res., 46, 2018
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5WZ4
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5WZF
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5X3T
| VapBC from Mycobacterium tuberculosis | Descriptor: | Antitoxin VapB26, MAGNESIUM ION, Ribonuclease VapC26 | Authors: | Kang, S.M, Kim, D.H, Yoon, H.J, Lee, B.J. | Deposit date: | 2017-02-07 | Release date: | 2017-06-07 | Last modified: | 2017-12-06 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Functional details of the Mycobacterium tuberculosis VapBC26 toxin-antitoxin system based on a structural study: insights into unique binding and antibiotic peptides. Nucleic Acids Res., 45, 2017
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5L6L
| Structure of Caulobacter crescentus VapBC1 bound to operator DNA | Descriptor: | DNA (27-MER), Ribonuclease VapC, VapB family protein | Authors: | Bendtsen, K.L, Xu, K, Luckmann, M, Brodersen, D.E. | Deposit date: | 2016-05-30 | Release date: | 2016-12-28 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Toxin inhibition in C. crescentus VapBC1 is mediated by a flexible pseudo-palindromic protein motif and modulated by DNA binding. Nucleic Acids Res., 45, 2017
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5K8J
| Structure of Caulobacter crescentus VapBC1 (apo form) | Descriptor: | GLYCEROL, Ribonuclease VapC, VapB family protein | Authors: | Bendtsen, K.L, Xu, K, Luckmann, M, Brodersen, D.E. | Deposit date: | 2016-05-30 | Release date: | 2016-12-28 | Last modified: | 2018-01-17 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Toxin inhibition in C. crescentus VapBC1 is mediated by a flexible pseudo-palindromic protein motif and modulated by DNA binding. Nucleic Acids Res., 45, 2017
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5L6M
| Structure of Caulobacter crescentus VapBC1 (VapB1deltaC:VapC1 form) | Descriptor: | GLYCEROL, MALONATE ION, Ribonuclease VapC, ... | Authors: | Bendtsen, K.L, Xu, K, Luckmann, M, Brodersen, D.E. | Deposit date: | 2016-05-30 | Release date: | 2016-12-28 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Toxin inhibition in C. crescentus VapBC1 is mediated by a flexible pseudo-palindromic protein motif and modulated by DNA binding. Nucleic Acids Res., 45, 2017
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5ECY
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5SV2
| Toxin VapC21 from Mycobacterium tuberculosis | Descriptor: | Ribonuclease VapC21 | Authors: | Valadares, N.F. | Deposit date: | 2016-08-04 | Release date: | 2016-09-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.31 Å) | Cite: | Crystal structure of VapC21 from Mycobacterium tuberculosis at 1.31 angstrom resolution. Biochem.Biophys.Res.Commun., 478, 2016
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5ECW
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5ED0
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5ECD
| Structure of the Shigella flexneri VapC mutant D98N crystal form 1 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, tRNA(fMet)-specific endonuclease VapC | Authors: | Xu, K. | Deposit date: | 2015-10-20 | Release date: | 2016-02-17 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structural analysis of the active site architecture of the VapC toxin from Shigella flexneri. Proteins, 84, 2016
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4XGQ
| Crystal structure of addiction module from Mycobacterial species | Descriptor: | Antitoxin VapB30, MAGNESIUM ION, Ribonuclease VapC30 | Authors: | Lee, B.-J, Lee, I.-G, Lee, S.J. | Deposit date: | 2015-01-02 | Release date: | 2015-08-12 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and functional studies of the Mycobacterium tuberculosis VapBC30 toxin-antitoxin system: implications for the design of novel antimicrobial peptides Nucleic Acids Res., 43, 2015
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4XGR
| Crystal structure of addiction module from Mycobacterial species | Descriptor: | Antitoxin VapB30, MAGNESIUM ION, Ribonuclease VapC30 | Authors: | Lee, B.-J, Lee, I.-G, Lee, S.J. | Deposit date: | 2015-01-02 | Release date: | 2015-08-12 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and functional studies of the Mycobacterium tuberculosis VapBC30 toxin-antitoxin system: implications for the design of novel antimicrobial peptides Nucleic Acids Res., 43, 2015
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4CHG
| Crystal structure of VapBC15 complex from Mycobacterium tuberculosis | Descriptor: | ANTITOXIN VAPB15, MAGNESIUM ION, MANGANESE (II) ION, ... | Authors: | Das, U, Pogenberg, V, Tiruttani Subhramanyam, U.K, Wilmanns, M, Srinivasan, A, Gourinath, S. | Deposit date: | 2013-12-02 | Release date: | 2014-11-12 | Last modified: | 2018-03-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure of the Vapbc-15 Complex from Mycobacterium Tuberculosis Reveals a Two-Metal Ion Dependent Pin-Domain Ribonuclease And a Variable Mode of Toxin-Antitoxin Assembly. J.Struct.Biol., 188, 2014
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3ZVK
| Crystal structure of VapBC2 from Rickettsia felis bound to a DNA fragment from their promoter | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ANTITOXIN OF TOXIN-ANTITOXIN SYSTEM VAPB, DNA, ... | Authors: | Mate, M.J, Ortiz-Lombardia, M, Cambillau, C. | Deposit date: | 2011-07-25 | Release date: | 2011-12-14 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of the DNA-Bound Vapbc2 Antitoxin/Toxin Pair from Rickettsia Felis. Nucleic Acids Res., 40, 2012
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3TND
| Crystal structure of Shigella flexneri VapBC toxin-antitoxin complex | Descriptor: | Antitoxin VapB, SODIUM ION, SULFATE ION, ... | Authors: | Dienemann, C, Boggild, A, Winther, K.S, Gerdes, K, Brodersen, D.E. | Deposit date: | 2011-09-01 | Release date: | 2011-11-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structure of the VapBC Toxin-Antitoxin Complex from Shigella flexneri Reveals a Hetero-Octameric DNA-Binding Assembly. J.Mol.Biol., 414, 2011
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3IX7
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