6W9N
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3T7L
| Crystal structure of the FYVE domain of endofin (ZFYVE16) at 1.1A resolution | Descriptor: | 1,2-ETHANEDIOL, ZINC ION, Zinc finger FYVE domain-containing protein 16 | Authors: | Chaikuad, A, Williams, E, Guo, K, Sanvitale, C, Berridge, G, Krojer, T, Muniz, J.R.C, Canning, P, Phillips, C, Shrestha, A, von Delft, F, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A, Structural Genomics Consortium (SGC) | Deposit date: | 2011-07-30 | Release date: | 2011-08-31 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.09 Å) | Cite: | Crystal structure of the FYVE domain of endofin (ZFYVE16) at 1.1A resolution To be Published
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1JOC
| EEA1 homodimer of C-terminal FYVE domain bound to inositol 1,3-diphosphate | Descriptor: | Early Endosomal Autoantigen 1, PHOSPHORIC ACID MONO-(2,3,4,6-TETRAHYDROXY-5-PHOSPHONOOXY-CYCLOHEXYL) ESTER, ZINC ION | Authors: | Dumas, J.J, Merithew, E, Rajamani, D, Hayes, S, Lawe, D, Corvera, S, Lambright, D.G. | Deposit date: | 2001-07-27 | Release date: | 2001-12-28 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Multivalent endosome targeting by homodimeric EEA1. Mol.Cell, 8, 2001
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2YW8
| Crystal structure of human RUN and FYVE domain-containing protein | Descriptor: | RUN and FYVE domain-containing protein 1, SULFATE ION, ZINC ION | Authors: | Wang, H, Kishishita, S, Murayama, K, Takemoto, C, Terada, T, Shirouzu, M, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-04-20 | Release date: | 2008-04-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of human RUN and FYVE domain-containing protein To be Published
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2YQM
| Solution structure of the FYVE domain in zinc finger FYVE domain-containing protein 12 | Descriptor: | RUN and FYVE domain-containing protein 1, ZINC ION | Authors: | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2007-03-30 | Release date: | 2007-10-02 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the FYVE domain in zinc finger FYVE domain-containing protein 12 To be Published
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1HYJ
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1HYI
| SOLUTION STRUCTURE OF THE EEA1 FYVE DOMAIN COMPLEXED WITH INOSITOL 1,3-BISPHOSPHATE | Descriptor: | ENDOSOME-ASSOCIATED PROTEIN, PHOSPHORIC ACID MONO-(2,3,4,6-TETRAHYDROXY-5-PHOSPHONOOXY-CYCLOHEXYL) ESTER, ZINC ION | Authors: | Kutateladze, T, Overduin, M. | Deposit date: | 2001-01-19 | Release date: | 2001-03-14 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural mechanism of endosome docking by the FYVE domain. Science, 291, 2001
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1VFY
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1X4U
| Solution structure of the FYVE domain from human FYVE domain containing 27 isoform b protein | Descriptor: | ZINC ION, Zinc finger, FYVE domain containing 27 isoform b | Authors: | Tomizawa, T, Kigawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-05-15 | Release date: | 2005-11-15 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the FYVE domain from human FYVE domain containing 27 isoform b protein To be Published
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1WFK
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4AVX
| Hepatocyte Growth Factor-Regulated Tyrosine Kinase Substrate (Hgs-Hrs) bound to an IP2 compound at 1.68 A Resolution | Descriptor: | 1,2-ETHANEDIOL, HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE, PHOSPHORIC ACID MONO-(2,3,4,6-TETRAHYDROXY-5-PHOSPHONOOXY-CYCLOHEXYL) ESTER, ... | Authors: | Williams, E, Canning, P, Shrestha, L, Krojer, T, Vollmar, M, Slowey, A, Conway, S, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Bullock, A. | Deposit date: | 2012-05-30 | Release date: | 2012-06-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Crystal Structure of the Tandem Vhs and Fyve Domains of Hepatocyte Growth Factor-Regulated Tyrosine Kinase Substrate (Hgs-Hrs) Bound to an Ip2 Compound at 1.68 A Resolution To be Published
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1DVP
| CRYSTAL STRUCTURE OF THE VHS AND FYVE TANDEM DOMAINS OF HRS, A PROTEIN INVOLVED IN MEMBRANE TRAFFICKING AND SIGNAL TRANSDUCTION | Descriptor: | CITRIC ACID, HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE, ZINC ION | Authors: | Mao, Y, Nickitenko, A, Duan, X, Lloyd, T.E, Wu, M.N, Bellen, H, Quiocho, F.A. | Deposit date: | 2000-01-21 | Release date: | 2000-03-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of the VHS and FYVE tandem domains of Hrs, a protein involved in membrane trafficking and signal transduction. Cell(Cambridge,Mass.), 100, 2000
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3ZYQ
| Crystal structure of the tandem VHS and FYVE domains of Hepatocyte growth factor-regulated tyrosine kinase substrate (HGS-Hrs) at 1.48 A resolution | Descriptor: | 1,2-ETHANEDIOL, HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE, SULFATE ION, ... | Authors: | Muniz, J.R.C, Ayinampudi, V, Shrestha, L, Krojer, T, Vollmar, M, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Bullock, A. | Deposit date: | 2011-08-24 | Release date: | 2011-09-07 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Crystal Structure of the Tandem Vhs and Fyve Domains of Hepatocyte Growth Factor-Regulated Tyrosine Kinase Substrate (Hgs-Hrs) at 1.48 A Resolution To be Published
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3MPX
| Crystal structure of the DH and PH-1 domains of human FGD5 | Descriptor: | FYVE, RhoGEF and PH domain-containing protein 5, UNKNOWN ATOM OR ION | Authors: | Shen, Y, Nedyalkova, L, Tong, Y, Tempel, W, Crombet, L, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | Deposit date: | 2010-04-27 | Release date: | 2010-06-23 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of the DH and PH-1 domains of human FGD5 TO BE PUBLISHED
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9F43
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9F45
| cryo-EM structure of human LST2 bound to human mTOR complex 1 | Descriptor: | INOSITOL HEXAKISPHOSPHATE, Lateral signaling target protein 2 homolog, Regulatory-associated protein of mTOR, ... | Authors: | Craigie, L.M, Maier, T. | Deposit date: | 2024-04-26 | Release date: | 2024-08-14 | Last modified: | 2024-08-28 | Method: | ELECTRON MICROSCOPY (3.74 Å) | Cite: | mTORC1 phosphorylates and stabilizes LST2 to negatively regulate EGFR. Proc.Natl.Acad.Sci.USA, 121, 2024
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