2PRH
| The structures of apo- and inhibitor bound human dihydroorotate dehydrogenase reveal conformational flexibility within the inhibitor binding site | Descriptor: | 6-CHLORO-2-(2'-FLUOROBIPHENYL-4-YL)-3-METHYLQUINOLINE-4-CARBOXYLIC ACID, DECYLAMINE-N,N-DIMETHYL-N-OXIDE, Dihydroorotate dehydrogenase, ... | Authors: | Walse, B, Dufe, V.T, Al-Karadaghi, S. | Deposit date: | 2007-05-04 | Release date: | 2008-05-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | The structures of human dihydroorotate dehydrogenase with and without inhibitor reveal conformational flexibility in the inhibitor and substrate binding sites Biochemistry, 47, 2008
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2PZW
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2PQD
| A100G CP4 EPSPS liganded with (R)-difluoromethyl tetrahedral reaction intermediate analog | Descriptor: | (3R,4S,5R)-5-[(1R)-1-CARBOXY-2,2-DIFLUORO-1-(PHOSPHONOOXY)ETHOXY]-4-HYDROXY-3-(PHOSPHONOOXY)CYCLOHEX-1-ENE-1-CARBOXYLIC ACID, 3-phosphoshikimate 1-carboxyvinyltransferase | Authors: | Healy-Fried, M.L, Funke, T, Han, H, Schonbrunn, E. | Deposit date: | 2007-05-01 | Release date: | 2008-03-11 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Differential inhibition of class I and class II 5-enolpyruvylshikimate-3-phosphate synthases by tetrahedral reaction intermediate analogues. Biochemistry, 46, 2007
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2Q42
| Ensemble refinement of the protein crystal structure of glyoxalase II from Arabidopsis thaliana gene At2g31350 | Descriptor: | ACETIC ACID, DI(HYDROXYETHYL)ETHER, FE (III) ION, ... | Authors: | Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2007-05-31 | Release date: | 2007-06-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.742 Å) | Cite: | Ensemble refinement of protein crystal structures: validation and application. Structure, 15, 2007
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2Q4N
| Ensemble refinement of the crystal structure of protein from Arabidopsis thaliana At1g79260 | Descriptor: | Uncharacterized protein At1g79260 | Authors: | Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2007-05-31 | Release date: | 2007-06-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.32 Å) | Cite: | Ensemble refinement of protein crystal structures: validation and application. Structure, 15, 2007
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2Q4R
| Ensemble refinement of the protein crystal structure of human phosphomannomutase 2 (PMM2) | Descriptor: | 1,2-ETHANEDIOL, GLYCINE, Phosphomannomutase 2 | Authors: | Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2007-05-31 | Release date: | 2007-06-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Ensemble refinement of protein crystal structures: validation and application. Structure, 15, 2007
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2PW7
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2NQ9
| High resolution crystal structure of Escherichia coli endonuclease IV (Endo IV) Y72A mutant bound to damaged DNA | Descriptor: | 5'-D(*AP*TP*AP*TP*CP*T)-3', 5'-D(*AP*TP*CP*TP*GP*AP*AP*GP*TP*AP*T)-3', 5'-D(P*(3DR)P*AP*GP*AP*T)-3', ... | Authors: | Garcin-Hosfield, E.D, Hosfield, D.J, Tainer, J.A. | Deposit date: | 2006-10-30 | Release date: | 2007-11-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | DNA apurinic-apyrimidinic site binding and excision by endonuclease IV. Nat.Struct.Mol.Biol., 15, 2008
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2NQK
| MoeA D59N mutant | Descriptor: | Molybdopterin biosynthesis protein moeA | Authors: | Nicolas, J, Xiang, S, Schindelin, H, Rajagopalan, K.V. | Deposit date: | 2006-10-31 | Release date: | 2007-01-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Mutational Analysis of Escherichia coli MoeA: Two Functional Activities Map to the Active Site Cleft. Biochemistry, 46, 2007
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2NQ2
| An inward-facing conformation of a putative metal-chelate type ABC transporter. | Descriptor: | Hypothetical ABC transporter ATP-binding protein HI1470, Hypothetical ABC transporter permease protein HI1471 | Authors: | Pinkett, H.P, Lee, A.T, Lum, P, Locher, K.P, Rees, D.C. | Deposit date: | 2006-10-30 | Release date: | 2007-01-02 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | An inward-facing conformation of a putative metal-chelate-type ABC transporter. Science, 315, 2007
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2NQS
| MoeA E188A | Descriptor: | GLYCEROL, Molybdopterin biosynthesis protein moeA | Authors: | Nicolas, J, Xiang, S, Schindelin, H, Rajagopalan, K.V. | Deposit date: | 2006-10-31 | Release date: | 2007-01-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Mutational Analysis of Escherichia coli MoeA: Two Functional Activities Map to the Active Site Cleft. Biochemistry, 46, 2007
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2NNQ
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2NL9
| Crystal structure of the Mcl-1:Bim BH3 complex | Descriptor: | Bcl-2-like protein 11, CHLORIDE ION, FUSION PROTEIN CONSISTING OF Induced myeloid leukemia cell differentiation protein Mcl-1 homolog, ... | Authors: | Czabotar, P.E, Colman, P.M. | Deposit date: | 2006-10-19 | Release date: | 2007-03-27 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structural insights into the degradation of Mcl-1 induced by BH3 domains. Proc.Natl.Acad.Sci.USA, 104, 2007
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2NOV
| Breakage-reunion domain of S.pneumoniae topo IV: crystal structure of a gram-positive quinolone target | Descriptor: | DNA topoisomerase 4 subunit A | Authors: | Laponogov, I, Veselkov, D.A, Sohi, M.K, Pan, X.S, Achari, A, Yang, C, Ferrara, J.D, Fisher, L.M, Sanderson, M.R. | Deposit date: | 2006-10-26 | Release date: | 2006-11-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.67 Å) | Cite: | Breakage-Reunion Domain of Streptococcus pneumoniae Topoisomerase IV: Crystal Structure of a Gram-Positive Quinolone Target. PLoS ONE, 2, 2007
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2NQM
| MoeA T100A mutant | Descriptor: | Molybdopterin biosynthesis protein moeA | Authors: | Nicoas, J, Xiang, S, Schindelin, H, Rajagopalan, K.V. | Deposit date: | 2006-10-31 | Release date: | 2007-01-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Mutational Analysis of Escherichia coli MoeA: Two Functional Activities Map to the Active Site Cleft. Biochemistry, 46, 2007
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2NPH
| Crystal structure of HIV1 protease in situ product complex | Descriptor: | PROTEASE RETROPEPSIN, pentapeptide fragment, tetrapeptide fragment | Authors: | Hosur, M.V, Das, A, Prashar, V. | Deposit date: | 2006-10-27 | Release date: | 2006-12-19 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal structure of HIV-1 protease in situ product complex and observation of a low-barrier hydrogen bond between catalytic aspartates Proc.Natl.Acad.Sci.Usa, 103, 2006
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2NQU
| MoeA E188Q | Descriptor: | GLYCEROL, Molybdopterin biosynthesis protein moeA | Authors: | Nicolas, J, Xiang, S, Schindelin, H, Rajagopalan, K.V. | Deposit date: | 2006-10-31 | Release date: | 2007-01-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Mutational Analysis of Escherichia coli MoeA: Two Functional Activities Map to the Active Site Cleft. Biochemistry, 46, 2007
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2NQH
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2NQQ
| MoeA R137Q | Descriptor: | GLYCEROL, Molybdopterin biosynthesis protein moeA | Authors: | Nicolas, J, Xiang, S, Schindelin, H, Rajagopalan, K.V. | Deposit date: | 2006-10-31 | Release date: | 2007-01-16 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Mutational Analysis of Escherichia coli MoeA: Two Functional Activities Map to the Active Site Cleft. Biochemistry, 46, 2007
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2Q3M
| Ensemble refinement of the protein crystal structure of an Arabidopsis thaliana putative steroid sulphotransferase | Descriptor: | Flavonol sulfotransferase-like, MALONIC ACID | Authors: | Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2007-05-30 | Release date: | 2007-06-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Ensemble refinement of protein crystal structures: validation and application. Structure, 15, 2007
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2Q4B
| Ensemble refinement of the protein crystal structure of selenomethionyl gene product from Arabidopsis thaliana At5g02240 in space group P21212 | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Protein At5g02240 | Authors: | Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2007-05-31 | Release date: | 2007-06-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.096 Å) | Cite: | Ensemble refinement of protein crystal structures: validation and application. Structure, 15, 2007
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2Q4V
| Ensemble refinement of the protein crystal structure of thialysine n-acetyltransferase (SSAT2) from Homo sapiens | Descriptor: | ACETYL COENZYME *A, Diamine acetyltransferase 2 | Authors: | Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2007-05-31 | Release date: | 2007-06-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.842 Å) | Cite: | Ensemble refinement of protein crystal structures: validation and application. Structure, 15, 2007
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2Q3O
| Ensemble refinement of the protein crystal structure of 12-oxo-phytodienoate reductase isoform 3 | Descriptor: | 12-oxophytodienoate reductase 3, FLAVIN MONONUCLEOTIDE | Authors: | Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2007-05-30 | Release date: | 2007-06-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Ensemble refinement of protein crystal structures: validation and application. Structure, 15, 2007
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2Q4U
| Ensemble refinement of the crystal structure of an EF-hand protein from Danio rerio Dr.36843 | Descriptor: | Protein Zgc:100843 | Authors: | Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2007-05-31 | Release date: | 2007-06-19 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Ensemble refinement of protein crystal structures: validation and application. Structure, 15, 2007
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2Q7D
| Crystal Structure of Human Inositol 1,3,4-Trisphosphate 5/6-kinase (ITPK1) in complex with AMPPNP and Mn2+ | Descriptor: | Inositol-tetrakisphosphate 1-kinase, MANGANESE (II) ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Chamberlain, P.P, Lesley, S.A, Spraggon, G. | Deposit date: | 2007-06-06 | Release date: | 2007-07-03 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Integration of inositol phosphate signaling pathways via human ITPK1. J.Biol.Chem., 282, 2007
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