5DJ3
 
 | | Structure of the PLP-Dependent L-Arginine Hydroxylase MppP with D-Arginine Bound | | Descriptor: | (E)-N~2~-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-D-arginine, MAGNESIUM ION, PLP-Dependent L-Arginine Hydroxylase MppP | | Authors: | Silvaggi, N.R, Han, L. | | Deposit date: | 2015-09-01 | | Release date: | 2015-11-25 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.227 Å) | | Cite: | Streptomyces wadayamensis MppP Is a Pyridoxal 5'-Phosphate-Dependent l-Arginine alpha-Deaminase, gamma-Hydroxylase in the Enduracididine Biosynthetic Pathway.
Biochemistry, 54, 2015
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1HTZ
 | | CRYSTAL STRUCTURE OF TEM52 BETA-LACTAMASE | | Descriptor: | BETA-LACTAMASE MUTANT TEM52 | | Authors: | Stevens, R.C, Orencia, M.C. | | Deposit date: | 2001-01-03 | | Release date: | 2001-03-21 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Predicting the emergence of antibiotic resistance by directed evolution and structural analysis.
Nat.Struct.Biol., 8, 2001
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5DJP
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2I9D
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2I3V
 | | Measurement of conformational changes accompanying desensitization in an ionotropic glutamate receptor: Structure of G725C mutant | | Descriptor: | GLUTAMIC ACID, Glutamate receptor 2, ZINC ION | | Authors: | Armstrong, N, Jasti, J, Beich-Frandsen, M, Gouaux, E. | | Deposit date: | 2006-08-21 | | Release date: | 2006-10-17 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Measurement of Conformational Changes accompanying Desensitization in an Ionotropic Glutamate Receptor.
Cell(Cambridge,Mass.), 127, 2006
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5XRU
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1I0I
 | | ANALYSIS OF AN INVARIANT ASPARTIC ACID IN HPRTS-GLUTAMINE MUTANT | | Descriptor: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 7-HYDROXY-PYRAZOLO[4,3-D]PYRIMIDINE, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE, ... | | Authors: | Canyuk, B, Focia, P.J, Eakin, A.E. | | Deposit date: | 2001-01-29 | | Release date: | 2002-05-29 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.06 Å) | | Cite: | The role for an invariant aspartic acid in hypoxanthine phosphoribosyltransferases is examined using saturation mutagenesis, functional analysis, and X-ray crystallography.
Biochemistry, 40, 2001
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2Y7Q
 | | THE HIGH-AFFINITY COMPLEX BETWEEN IGE AND ITS RECEPTOR FC EPSILON RI | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HIGH AFFINITY IMMUNOGLOBULIN EPSILON RECEPTOR SUBUNIT ALPHA, IG EPSILON CHAIN C REGION, ... | | Authors: | Davies, A.M, Holdom, M.D, Nettleship, J.E, Beavil, A.J, Owens, R.J, Sutton, B.J. | | Deposit date: | 2011-02-01 | | Release date: | 2011-04-20 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Conformational Changes in Ige Contribute to its Uniquely Slow Dissociation Rate from Receptor Fceri
Nat.Struct.Mol.Biol., 18, 2011
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3DE8
 | | Crystal Structure of a Dimeric Cytochrome cb562 Assembly Induced by Copper Coordination | | Descriptor: | CALCIUM ION, COPPER (II) ION, PROTOPORPHYRIN IX CONTAINING FE, ... | | Authors: | Salgado, E.N, Lewis, R.A, Rheingold, A.L, Tezcan, F.A. | | Deposit date: | 2008-06-08 | | Release date: | 2009-04-21 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.72 Å) | | Cite: | Control of protein oligomerization symmetry by metal coordination: C2 and C3 symmetrical assemblies through Cu(II) and Ni(II) coordination.
Inorg.Chem., 48, 2009
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1S88
 | | NMR structure of a DNA duplex with two INA nucleotides inserted opposite each other, dCTCAACXCAAGCT:dAGCTTGXGTTGAG | | Descriptor: | 5'-D(*AP*GP*CP*TP*TP*GP*(2DM)P*GP*TP*TP*GP*AP*G)-3', 5'-D(*CP*TP*CP*AP*AP*CP*(2DM)P*CP*AP*AP*GP*CP*T)-3' | | Authors: | Nielsen, C.B, Petersen, M, Pedersen, E.B, Hansen, P.E, Christensen, U.B. | | Deposit date: | 2004-01-31 | | Release date: | 2004-05-25 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | NMR structure determination of a modified DNA oligonucleotide containing a new intercalating nucleic acid.
Bioconjug.Chem., 15, 2004
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6U0X
 | | Crystal structure of Staphylococcal nuclease variant Delta+PHS Q123D at cryogenic temperature | | Descriptor: | CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease | | Authors: | Jeliazkov, J.R, Robinson, A.C, Berger, J.M, Garcia-Moreno E, B, Gray, J.G. | | Deposit date: | 2019-08-15 | | Release date: | 2019-08-28 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Toward the computational design of protein crystals with improved resolution.
Acta Crystallogr D Struct Biol, 75, 2019
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5OOT
 | | Structure of CHK1 10-pt. mutant complex with aminopyrimido-benzodiazepinone LRRK2 inhibitor | | Descriptor: | 2-[(2-methoxy-4-{[4-(4-methylpiperazin-1-yl)piperidin-1-yl]carbonyl}phenyl)amino]-5,11-dimethyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one, Serine/threonine-protein kinase Chk1 | | Authors: | Dokurno, P, Williamson, D.S, Acheson-Dossang, P, Chen, I, Murray, J.B, Shaw, T, Surgenor, A.E. | | Deposit date: | 2017-08-08 | | Release date: | 2017-10-25 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Design of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Crystallographic Surrogate Derived from Checkpoint Kinase 1 (CHK1).
J. Med. Chem., 60, 2017
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2HYR
 | | Crystal structure of a complex of griffithsin with maltose | | Descriptor: | 1,2-ETHANEDIOL, Griffithsin, MAGNESIUM ION, ... | | Authors: | Ziolkowska, N.E, Wlodawer, A. | | Deposit date: | 2006-08-07 | | Release date: | 2007-04-24 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.51 Å) | | Cite: | Crystallographic, thermodynamic, and molecular modeling studies of the mode of binding of oligosaccharides to the potent antiviral protein griffithsin.
Proteins, 67, 2007
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1WSE
 | | Co-crystal structure of E.coli RNase HI active site mutant (E48A*) with Mn2+ | | Descriptor: | MANGANESE (II) ION, Ribonuclease HI | | Authors: | Tsunaka, Y, Takano, K, Matsumura, H, Yamagata, Y, Kanaya, S. | | Deposit date: | 2004-11-05 | | Release date: | 2005-02-08 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Identification of Single Mn(2+) Binding Sites Required for Activation of the Mutant Proteins of E.coli RNase HI at Glu48 and/or Asp134 by X-ray Crystallography
J.Mol.Biol., 345, 2005
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1I0L
 | | ANALYSIS OF AN INVARIANT ASPARTIC ACID IN HPRTS-ASPARAGINE MUTANT | | Descriptor: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 7-HYDROXY-PYRAZOLO[4,3-D]PYRIMIDINE, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE, ... | | Authors: | Canyuk, B, Focia, P.J, Eakin, A.E. | | Deposit date: | 2001-01-29 | | Release date: | 2002-05-29 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.72 Å) | | Cite: | The role for an invariant aspartic acid in hypoxanthine phosphoribosyltransferases is examined using saturation mutagenesis, functional analysis, and X-ray crystallography.
Biochemistry, 40, 2001
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5OQ8
 | | Structure of CHK1 12-pt. mutant complex with arylbenzamide LRRK2 inhibitor | | Descriptor: | 5-(4-methylpiperazin-1-yl)-2-phenylmethoxy-~{N}-pyridin-3-yl-benzamide, Serine/threonine-protein kinase Chk1 | | Authors: | Dokurno, P, Williamson, D.S, Acheson-Dossang, P, Chen, I, Murray, J.B, Shaw, T, Surgenor, A.E. | | Deposit date: | 2017-08-10 | | Release date: | 2017-10-25 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Design of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Crystallographic Surrogate Derived from Checkpoint Kinase 1 (CHK1).
J. Med. Chem., 60, 2017
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4C0J
 | | Crystal structure of Drosophila Miro EF hand and cGTPase domains in the apo state (Apo-MiroS) | | Descriptor: | L-HOMOSERINE, MITOCHONDRIAL RHO GTPASE, SODIUM ION, ... | | Authors: | Klosowiak, J.L, Focia, P.J, Wawrzak, Z, Chakravarthy, S, Landahl, E.C, Freymann, D.M, Rice, S.E. | | Deposit date: | 2013-08-05 | | Release date: | 2013-10-09 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.82 Å) | | Cite: | Structural Coupling of the EF Hand and C-Terminal Gtpase Domains in the Mitochondrial Protein Miro.
Embo Rep., 14, 2013
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5DKU
 | | C-terminal His tagged apPOL exonuclease mutant | | Descriptor: | MAGNESIUM ION, Prex DNA polymerase | | Authors: | Milton, M.E, Honzatko, R.B, Choe, J.Y, Nelson, S.W. | | Deposit date: | 2015-09-04 | | Release date: | 2016-08-10 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal Structure of the Apicoplast DNA Polymerase from Plasmodium falciparum: The First Look at a Plastidic A-Family DNA Polymerase.
J.Mol.Biol., 428, 2016
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4C0K
 | | Crystal structure of Drosophila Miro EF hand and cGTPase domains bound to one calcium ion (Ca-MiroS) | | Descriptor: | CALCIUM ION, L-HOMOSERINE, MITOCHONDRIAL RHO GTPASE, ... | | Authors: | Klosowiak, J.L, Focia, P.J, Wawrzak, Z, Chakravarthy, S, Landahl, E.C, Freymann, D.M, Rice, S.E. | | Deposit date: | 2013-08-05 | | Release date: | 2013-10-09 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.801 Å) | | Cite: | Structural Coupling of the EF Hand and C-Terminal Gtpase Domains in the Mitochondrial Protein Miro.
Embo Rep., 14, 2013
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4C0L
 | | Crystal structure of Drosophila Miro EF hand and cGTPase domains bound to one magnesium ion and Mg:GDP (MgGDP-MiroS) | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, L-HOMOSERINE, MAGNESIUM ION, ... | | Authors: | Klosowiak, J.L, Focia, P.J, Wawrzak, Z, Chakravarthy, S, Landahl, E.C, Freymann, D.M, Rice, S.E. | | Deposit date: | 2013-08-05 | | Release date: | 2013-10-09 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural Coupling of the EF Hand and C-Terminal Gtpase Domains in the Mitochondrial Protein Miro.
Embo Rep., 14, 2013
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5XJV
 | | Two intermediate states of conformation switch in dual specificity phosphatase 13a | | Descriptor: | Dual specificity protein phosphatase 13 isoform A, PHOSPHATE ION | | Authors: | Wei, C.H, Min, H.G, Chun, H.J, Ryu, S.E. | | Deposit date: | 2017-05-04 | | Release date: | 2018-04-11 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Two intermediate states of the conformational switch in dual specificity phosphatase 13a
Pharmacol. Res., 128, 2018
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1I13
 | | ANALYSIS OF AN INVARIANT ASPARTIC ACID IN HPRTS-ALANINE MUTANT | | Descriptor: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 7-HYDROXY-PYRAZOLO[4,3-D]PYRIMIDINE, FORMIC ACID, ... | | Authors: | Canyuk, B, Focia, P.J, Eakin, A.E. | | Deposit date: | 2001-01-30 | | Release date: | 2002-05-29 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.84 Å) | | Cite: | The role for an invariant aspartic acid in hypoxanthine phosphoribosyltransferases is examined using saturation mutagenesis, functional analysis, and X-ray crystallography.
Biochemistry, 40, 2001
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126D
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1I14
 | | ANALYSIS OF AN INVARIANT ASPARTIC ACID IN HPRTS-GLUTAMIC ACID MUTANT | | Descriptor: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 7-HYDROXY-PYRAZOLO[4,3-D]PYRIMIDINE, HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE, ... | | Authors: | Canyuk, B, Focia, P.J, Eakin, A.E. | | Deposit date: | 2001-01-30 | | Release date: | 2002-05-29 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (1.92 Å) | | Cite: | The role for an invariant aspartic acid in hypoxanthine phosphoribosyltransferases is examined using saturation mutagenesis, functional analysis, and X-ray crystallography.
Biochemistry, 40, 2001
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1IBT
 | | STRUCTURE OF THE D53,54N MUTANT OF HISTIDINE DECARBOXYLASE AT-170 C | | Descriptor: | HISTIDINE DECARBOXYLASE ALPHA CHAIN, HISTIDINE DECARBOXYLASE BETA CHAIN | | Authors: | Worley, S, Schelp, E, Monzingo, A.F, Ernst, S, Robertus, J.D. | | Deposit date: | 2001-03-29 | | Release date: | 2002-03-13 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure and cooperativity of a T-state mutant of histidine decarboxylase from Lactobacillus 30a.
Proteins, 46, 2002
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