2ENV
| |
6NMD
| cryo-EM Structure of the LbCas12a-crRNA-AcrVA1 complex | Descriptor: | AcrVA1, Cpf1, MAGNESIUM ION, ... | Authors: | Chang, L, Li, Z, Zhang, H. | Deposit date: | 2019-01-10 | Release date: | 2019-06-12 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.49 Å) | Cite: | Structural Basis for the Inhibition of CRISPR-Cas12a by Anti-CRISPR Proteins. Cell Host Microbe, 25, 2019
|
|
6NMA
| CryoEM structure of the LbCas12a-crRNA-AcrVA4 complex | Descriptor: | AcrVA1, Cpf1, MAGNESIUM ION, ... | Authors: | Chang, L, Li, Z, Zhang, H. | Deposit date: | 2019-01-10 | Release date: | 2019-06-12 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.38 Å) | Cite: | Structural Basis for the Inhibition of CRISPR-Cas12a by Anti-CRISPR Proteins. Cell Host Microbe, 25, 2019
|
|
6GBZ
| 50S ribosomal subunit assembly intermediate state 5 | Descriptor: | 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | Authors: | Nikolay, R, Hilal, T, Qin, B, Loerke, J, Buerger, J, Mielke, T, Spahn, C.M.T. | Deposit date: | 2018-04-16 | Release date: | 2018-06-20 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural Visualization of the Formation and Activation of the 50S Ribosomal Subunit during In Vitro Reconstitution. Mol. Cell, 70, 2018
|
|
7KYM
| |
7L19
| Crystal structure of the MarR family transcriptional regulator from Enterobacter soli strain LF7 bound to Indole 3 acetic acid | Descriptor: | 1H-INDOL-3-YLACETIC ACID, MarR family transcriptional regulator, NICKEL (II) ION | Authors: | Lietzan, A.D, Walton, W.G, Redinbo, M.R, Dangl, J.L. | Deposit date: | 2020-12-14 | Release date: | 2021-12-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.77 Å) | Cite: | Diverse MarR bacterial regulators of auxin catabolism in the plant microbiome. Nat Microbiol, 7, 2022
|
|
7L1I
| Crystal structure of the MarR family transcriptional regulator from Acineotobacter baumannii bound to Indole 3 acetic acid | Descriptor: | 1H-INDOL-3-YLACETIC ACID, MarR family multidrug resistance pump transcriptional regulator, NICKEL (II) ION | Authors: | Walton, W.G, Lietzan, A.D, Redinbo, M.R, Dangl, J.L. | Deposit date: | 2020-12-14 | Release date: | 2022-02-09 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Diverse MarR bacterial regulators of auxin catabolism in the plant microbiome. Nat Microbiol, 7, 2022
|
|
3ZMS
| LSD1-CoREST in complex with INSM1 peptide | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, INSULINOMA-ASSOCIATED PROTEIN 1, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A, ... | Authors: | Tortorici, M, Borrello, M.T, Tardugno, M, Chiarelli, L.R, Pilotto, S, Ciossani, G, Vellore, N.A, Cowan, J, O'Connell, M, Mai, A, Baron, R, Ganesan, A, Mattevi, A. | Deposit date: | 2013-02-12 | Release date: | 2013-06-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.96 Å) | Cite: | Protein Recognition by Small Peptide Reversible Inhibitors of the Chromatin-Modifying Lsd1/Corest Lysine Demethylase. Acs Chem.Biol., 8, 2013
|
|
2ZFW
| |
1H26
| CDK2/CyclinA in complex with an 11-residue recruitment peptide from p53 | Descriptor: | CELL DIVISION PROTEIN KINASE 2, CELLULAR TUMOR ANTIGEN P53, CYCLIN A2 | Authors: | Tews, I, Cheng, K.Y, Lowe, E.D, Noble, M.E.M, Brown, N.R, Gul, S, Gamblin, S, Johnson, L.N. | Deposit date: | 2002-07-31 | Release date: | 2003-02-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Specificity Determinants of Recruitment Peptides Bound to Phospho-Cdk2/Cyclin A Biochemistry, 41, 2002
|
|
4LDZ
| Crystal structure of the full-length response regulator DesR in the active state | Descriptor: | BERYLLIUM TRIFLUORIDE ION, GLYCEROL, MAGNESIUM ION, ... | Authors: | Trajtenberg, F, Larrieux, N, Buschiazzo, A. | Deposit date: | 2013-06-25 | Release date: | 2014-07-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Allosteric activation of bacterial response regulators: the role of the cognate histidine kinase beyond phosphorylation. MBio, 5, 2014
|
|
2EV0
| Bacillus subtilis manganese transport regulator (MNTR) bound to cadmium | Descriptor: | CADMIUM ION, Transcriptional regulator mntR | Authors: | Kliegman, J.I, Griner, S.L, Helmann, J.D, Brennan, R.G, Glasfeld, A. | Deposit date: | 2005-10-30 | Release date: | 2006-03-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural Basis for the Metal-Selective Activation of the Manganese Transport Regulator of Bacillus subtilis. Biochemistry, 45, 2006
|
|
2EV5
| Bacillus subtilis manganese transport regulator (MNTR) bound to calcium | Descriptor: | CALCIUM ION, Transcriptional regulator mntR | Authors: | Kliegman, J.I, Griner, S.L, Helmann, J.D, Brennan, R.G, Glasfeld, A. | Deposit date: | 2005-10-31 | Release date: | 2006-03-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Basis for the Metal-Selective Activation of the Manganese Transport Regulator of Bacillus subtilis. Biochemistry, 45, 2006
|
|
2EV6
| Bacillus subtilis manganese transport regulator (MNTR) bound to zinc | Descriptor: | CITRATE ANION, GLYCEROL, Transcriptional regulator mntR, ... | Authors: | Kliegman, J.I, Griner, S.L, Helmann, J.D, Brennan, R.G, Glasfeld, A. | Deposit date: | 2005-10-31 | Release date: | 2006-03-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural Basis for the Metal-Selective Activation of the Manganese Transport Regulator of Bacillus subtilis. Biochemistry, 45, 2006
|
|
2F5E
| Bacillus subtilis manganese transport regulator (MNTR) bound to manganese, AB conformation, pH 6.5 | Descriptor: | MANGANESE (II) ION, Transcriptional regulator mntR | Authors: | Kliegman, J.I, Griner, S.L, Helmann, J.D, Brennan, R.G, Glasfeld, A. | Deposit date: | 2005-11-25 | Release date: | 2006-03-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Basis for the Metal-Selective Activation of the Manganese Transport Regulator of Bacillus subtilis. Biochemistry, 45, 2006
|
|
1H25
| CDK2/Cyclin A in complex with an 11-residue recruitment peptide from retinoblastoma-associated protein | Descriptor: | CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, RETINOBLASTOMA-ASSOCIATED PROTEIN | Authors: | Tews, I, Cheng, K.Y, Lowe, E.D, Noble, M.E.M, Brown, N.R, Gul, S, Gamblin, S, Johnson, L.N. | Deposit date: | 2002-07-31 | Release date: | 2003-02-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Specificity Determinants of Recruitment Peptides Bound to Phospho-Cdk2/Cyclin A Biochemistry, 41, 2002
|
|
1H24
| CDK2/CyclinA in complex with a 9 residue recruitment peptide from E2F | Descriptor: | CELL DIVISION PROTEIN KINASE 2, CYCLIN A2, TRANSCRIPTION FACTOR E2F1 | Authors: | Tews, I, Cheng, K.Y, Lowe, E.D, Noble, M.E.M, Brown, N.R, Gul, S, Gamblin, S, Johnson, L.N. | Deposit date: | 2002-07-31 | Release date: | 2003-02-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Specificity Determinants of Recruitment Peptides Bound to Phospho-Cdk2/Cyclin A Biochemistry, 41, 2002
|
|
2F5F
| Bacillus subtilis manganese transport regulator (MNTR) bound to manganese, AC conformation, pH 8.5 | Descriptor: | MANGANESE (II) ION, Transcriptional regulator mntR | Authors: | Kliegman, J.I, Griner, S.L, Helmann, J.D, Brennan, R.G, Glasfeld, A. | Deposit date: | 2005-11-25 | Release date: | 2006-03-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Basis for the Metal-Selective Activation of the Manganese Transport Regulator of Bacillus subtilis. Biochemistry, 45, 2006
|
|
2FBI
| The crystal structure of transcriptional regulator PA4135 | Descriptor: | probable transcriptional regulator | Authors: | Lunin, V.V, Evdokimova, E, Kudritska, M, Cuff, M.E, Joachimiak, A, Edwards, A.M, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-12-09 | Release date: | 2005-12-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The crystal structure of transcriptional regulator PA4135 To be Published
|
|
2F5D
| Bacillus subtilis manganese transport regulator (MNTR) bound to manganese, AC conformation, pH 6.5 | Descriptor: | MANGANESE (II) ION, Transcriptional regulator mntR | Authors: | Kliegman, J.I, Griner, S.L, Helmann, J.D, Brennan, R.G, Glasfeld, A. | Deposit date: | 2005-11-25 | Release date: | 2006-03-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Basis for the Metal-Selective Activation of the Manganese Transport Regulator of Bacillus subtilis. Biochemistry, 45, 2006
|
|
3TI1
| CDK2 in complex with SUNITINIB | Descriptor: | 1,2-ETHANEDIOL, Cyclin-dependent kinase 2, N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbo xamide | Authors: | Alam, R, Schonbrunn, E. | Deposit date: | 2011-08-19 | Release date: | 2012-08-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | A Novel Approach to the Discovery of Small-Molecule Ligands of CDK2. Chembiochem, 13, 2012
|
|
1DI8
| THE STRUCTURE OF CYCLIN-DEPENDENT KINASE 2 (CDK2) IN COMPLEX WITH 4-[3-HYDROXYANILINO]-6,7-DIMETHOXYQUINAZOLINE | Descriptor: | 4-[3-HYDROXYANILINO]-6,7-DIMETHOXYQUINAZOLINE, CYCLIN-DEPENDENT KINASE 2 | Authors: | Shewchuk, L, Hassell, A, Kuyper, L.F. | Deposit date: | 1999-11-29 | Release date: | 2000-11-29 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Binding mode of the 4-anilinoquinazoline class of protein kinase inhibitor: X-ray crystallographic studies of 4-anilinoquinazolines bound to cyclin-dependent kinase 2 and p38 kinase. J.Med.Chem., 43, 2000
|
|
3TIY
| CDK2 in complex with NSC 35676 | Descriptor: | 1,2-ETHANEDIOL, 2,3,4,6-tetrahydroxy-5H-benzo[7]annulen-5-one, Cyclin-dependent kinase 2 | Authors: | Alam, R, Schonbrunn, E. | Deposit date: | 2011-08-22 | Release date: | 2012-08-22 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | A Novel Approach to the Discovery of Small-Molecule Ligands of CDK2. Chembiochem, 13, 2012
|
|
4ENY
| Crystal Structure of Pim-1 kinase in complex with (2E,5Z)-2-(2-chlorophenylimino)-5-(4-hydroxy-3-methoxybenzylidene)thiazolidin-4-one | Descriptor: | (2Z,5Z)-2-[(2-chlorophenyl)imino]-5-(4-hydroxy-3-methoxybenzylidene)-1,3-thiazolidin-4-one, DIMETHYL SULFOXIDE, GLYCEROL, ... | Authors: | Parker, L.J, Handa, N, Yokoyama, S. | Deposit date: | 2012-04-13 | Release date: | 2012-08-08 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.801 Å) | Cite: | Flexibility of the P-loop of Pim-1 kinase: observation of a novel conformation induced by interaction with an inhibitor Acta Crystallogr.,Sect.F, 68, 2012
|
|
6DMX
| HBZ56 in complex with KIX and c-Myb | Descriptor: | BZIP factor, CREB-binding protein, Transcriptional activator Myb | Authors: | Yang, K, Wright, P.E, Stanfield, R.L. | Deposit date: | 2018-06-05 | Release date: | 2018-09-19 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis for cooperative regulation of KIX-mediated transcription pathways by the HTLV-1 HBZ activation domain. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|