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1PV7
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Crystal structure of lactose permease with TDG
Descriptor: Lactose permease, beta-D-galactopyranose-(1-1)-1-thio-beta-D-galactopyranose
Authors:Abramson, J, Smirnova, I, Kasho, V, Verner, G, Kaback, H.R, Iwata, S.
Deposit date:2003-06-26
Release date:2003-08-12
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structure and mechanism of the lactose permease of Escherichia coli
SCIENCE, 301, 2003
1PVF
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BU of 1pvf by Molmil
E.coli IPP isomerase in complex with diphosphate
Descriptor: DIPHOSPHATE, Isopentenyl-diphosphate delta-isomerase, MAGNESIUM ION, ...
Authors:Wouters, J, Durisotti, V, Oudjama, Y, Stalon, V, Droogmans, L.
Deposit date:2003-06-27
Release date:2004-07-06
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:E.coli Isopentenyl Diphosphate: Dimethylallyl Diphosphate isomerase in complex with diphosphate
To be Published
1HNA
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BU of 1hna by Molmil
CRYSTAL STRUCTURE OF HUMAN CLASS MU GLUTATHIONE TRANSFERASE GSTM2-2: EFFECTS OF LATTICE PACKING ON CONFORMATIONAL HETEROGENEITY
Descriptor: GLUTATHIONE S-(2,4 DINITROBENZENE), GLUTATHIONE S-TRANSFERASE
Authors:Raghunathan, S, Chandross, R.J, Kretsinger, R.H, Allison, T.J, Penington, C.J, Rule, G.S.
Deposit date:1993-10-15
Release date:1994-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of human class mu glutathione transferase GSTM2-2. Effects of lattice packing on conformational heterogeneity.
J.Mol.Biol., 238, 1994
1HUG
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BU of 1hug by Molmil
Differences in anionic inhibition of Human Carbonic Anhydrase I revealed from the structures of iodide and gold cyanide inhibitor complexes
Descriptor: CARBONIC ANHYDRASE I, GOLD (I) CYANIDE ION, ZINC ION
Authors:Kumar, V, Kannan, K.K.
Deposit date:1993-10-28
Release date:1994-04-30
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Differences in anionic inhibition of human carbonic anhydrase I revealed from the structures of iodide and gold cyanide inhibitor complexes.
Acta Crystallogr.,Sect.D, 50, 1994
8OE4
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BU of 8oe4 by Molmil
Cryo-EM structure of a pre-dimerized human IL-23 complete extracellular signaling complex.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1,Death-associated protein kinase 1, ...
Authors:Bloch, Y, Felix, J, Savvides, S.N.
Deposit date:2023-03-10
Release date:2024-02-07
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024
1HUW
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BU of 1huw by Molmil
THE CRYSTAL STRUCTURE OF AFFINITY-MATURED HUMAN GROWTH HORMONE AT 2 ANGSTROMS RESOLUTION
Descriptor: HUMAN GROWTH HORMONE
Authors:Ultsch, M.H, Somers, W.S, Kossiakoff, A.A, De Vos, A.M.
Deposit date:1993-09-22
Release date:1994-01-31
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of affinity-matured human growth hormone at 2 A resolution.
J.Mol.Biol., 236, 1994
1HXY
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BU of 1hxy by Molmil
CRYSTAL STRUCTURE OF STAPHYLOCOCCAL ENTEROTOXIN H IN COMPLEX WITH HUMAN MHC CLASS II
Descriptor: ENTEROTOXIN H, HEMAGGLUTININ, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, ...
Authors:Petersson, K, Hakansson, M, Nilsson, H, Forsberg, G, Svensson, L.A, Liljas, A, Walse, B.
Deposit date:2001-01-17
Release date:2001-06-27
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of a Superantigen Bound to MHC Class II Displays Zinc and Peptide Dependence
Embo J., 20, 2001
8ODX
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BU of 8odx by Molmil
Interleukin 12 receptor subunit beta-1 Fn domains in complex with antagonistic FAb4 fragment and VHH.
Descriptor: FAb4 Heavy chain, FAb4 Light chain, Interleukin-12 receptor subunit beta-1, ...
Authors:Bloch, Y, Savvides, S.N.
Deposit date:2023-03-09
Release date:2024-02-07
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (4.4 Å)
Cite:Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024
8OE0
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BU of 8oe0 by Molmil
Cryo-EM structure of a pre-dimerized murine IL-12 complete extracellular signaling complex (Class 2).
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1,Death-associated protein kinase 1, ...
Authors:Felix, J, Bloch, Y, Savvides, S.N.
Deposit date:2023-03-10
Release date:2024-02-07
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024
1HKI
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BU of 1hki by Molmil
Crystal structure of human chitinase in complex with glucoallosamidin B
Descriptor: 2-acetamido-2-deoxy-6-O-methyl-alpha-D-allopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHITOTRIOSIDASE, METHYL N-ACETYL ALLOSAMINE
Authors:Rao, F.V, Houston, D.R, Boot, R.G, Aerts, J.M.F.G, Sakuda, S, Van Aalten, D.M.F.
Deposit date:2003-03-10
Release date:2004-03-11
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal Structures of Allosamidin Derivatives in Complex with Human Macrophage Chitinase
J.Biol.Chem., 278, 2003
1HI3
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Eosinophil-derived Neurotoxin (EDN) - Adenosine 2'-5'-Diphosphate Complex
Descriptor: ADENOSINE-2'-5'-DIPHOSPHATE, EOSINOPHIL-DERIVED NEUROTOXIN
Authors:Leonidas, D.D, Boix, E, Prill, R, Suzuki, M, Turton, R, Minson, K, Swaminathan, G.J, Youle, R.J, Acharya, K.R.
Deposit date:2001-01-02
Release date:2001-05-31
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mapping the Ribonucleolytic Active Site of Eosinophil-Derived Neurotoxin (Edn): High Resolution Crystal Structures of Edn Complexes with Adenylic Nucleotide Inhibitors
J.Biol.Chem., 276, 2001
1Q1N
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BU of 1q1n by Molmil
APO AND HOLO STRUCTURES OF AN NADP(H)-DEPENDENT CINNAMYL ALCOHOL DEHYDROGENASE FROM SACCHAROMYCES CEREVISIAE
Descriptor: Hypothetical zinc-type alcohol dehydrogenase-like protein in PRE5-FET4 intergenic region, ZINC ION
Authors:Valencia, E, Larroy, C, Ochoa, W.F, Pares, X, Fita, I, Biosca, J.A.
Deposit date:2003-07-22
Release date:2004-08-03
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Apo and Holo Structures of an NADP(H)-dependent Cinnamyl Alcohol Dehydrogenase from Saccharomyces cerevisiae
J.Mol.Biol., 341, 2004
1Q20
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BU of 1q20 by Molmil
Crystal Structure of human cholesterol sulfotransferase (SULT2B1b) in the presence of PAP and pregnenolone
Descriptor: (3BETA)-3-HYDROXYPREGN-5-EN-20-ONE, ADENOSINE-3'-5'-DIPHOSPHATE, SODIUM ION, ...
Authors:Lee, K.A, Fuda, H, Lee, Y.C, Negishi, M, Strott, C.A, Pedersen, L.C.
Deposit date:2003-07-23
Release date:2003-11-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of human cholesterol sulfotransferase (SULT2B1b) in the presence of pregnenolone and 3'-phosphoadenosine 5'-phosphate. Rationale for specificity differences between prototypical SULT2A1 and the SULT2BG1 isoforms.
J.Biol.Chem., 278, 2003
1GAI
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BU of 1gai by Molmil
GLUCOAMYLASE-471 COMPLEXED WITH D-GLUCO-DIHYDROACARBOSE
Descriptor: 4,6-dideoxy-4-{[(1S,2S,3S,4R,5R)-2,3,4-trihydroxy-5-(hydroxymethyl)cyclohexyl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, GLUCOAMYLASE-471, alpha-D-mannopyranose, ...
Authors:Aleshin, A.E, Stoffer, B, Firsov, L.M, Svensson, B, Honzatko, R.B.
Deposit date:1996-03-06
Release date:1996-08-17
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystallographic complexes of glucoamylase with maltooligosaccharide analogs: relationship of stereochemical distortions at the nonreducing end to the catalytic mechanism.
Biochemistry, 35, 1996
1GC7
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BU of 1gc7 by Molmil
CRYSTAL STRUCTURE OF THE RADIXIN FERM DOMAIN
Descriptor: RADIXIN
Authors:Hamada, K, Shimizu, T, Matsui, T, Tsukita, S, Tsukita, S, Hakoshima, T.
Deposit date:2000-07-21
Release date:2000-09-20
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of the membrane-targeting and unmasking mechanisms of the radixin FERM domain.
EMBO J., 19, 2000
1GG3
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BU of 1gg3 by Molmil
CRYSTAL STRUCTURE OF THE PROTEIN 4.1R MEMBRANE BINDING DOMAIN
Descriptor: ERYTHROID MEMBRANE PROTEIN 4.1R
Authors:Han, B.G.
Deposit date:2000-07-11
Release date:2001-01-10
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Protein 4.1R core domain structure and insights into regulation of cytoskeletal organization.
Nat.Struct.Biol., 7, 2000
1PPJ
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BU of 1ppj by Molmil
Bovine cytochrome bc1 complex with stigmatellin and antimycin
Descriptor: 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-METHYL-BUTYRIC ACID 3-(3-FORMYLAMINO-2-HYDROXY-BENZOYLAMINO)-8-HEPTYL-2,6-DIMETHYL-4,9-DIOXO-[1,5]DIOXONAN-7-YL ESTER, AZIDE ION, ...
Authors:Huang, L.S, Cobessi, D, Tung, E.Y, Berry, E.A.
Deposit date:2003-06-16
Release date:2004-07-20
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Binding of the Respiratory Chain Inhibitor Antimycin to the Mitochondrial bc(1) Complex: A New Crystal Structure Reveals an Altered Intramolecular Hydrogen-bonding Pattern.
J.Mol.Biol., 351, 2005
1GGU
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BU of 1ggu by Molmil
HUMAN FACTOR XIII WITH CALCIUM BOUND IN THE ION SITE
Descriptor: CALCIUM ION, PROTEIN (COAGULATION FACTOR XIII)
Authors:Fox, B.A, Yee, V.C, Pederson, L.C, Trong, I.L, Bishop, P.D, Stenkamp, R.E, Teller, D.C.
Deposit date:1998-07-22
Release date:1999-09-16
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Identification of the calcium binding site and a novel ytterbium site in blood coagulation factor XIII by x-ray crystallography.
J.Biol.Chem., 274, 1999
1GLA
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BU of 1gla by Molmil
STRUCTURE OF THE REGULATORY COMPLEX OF ESCHERICHIA COLI IIIGLC WITH GLYCEROL KINASE
Descriptor: GLUCOSE-SPECIFIC PROTEIN IIIGlc, GLYCEROL, GLYCEROL KINASE
Authors:Hurley, J.H, Worthylake, D, Faber, H.R, Meadow, N.D, Roseman, S, Pettigrew, D.W, Remington, S.J.
Deposit date:1992-10-28
Release date:1993-10-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the regulatory complex of Escherichia coli IIIGlc with glycerol kinase.
Science, 259, 1993
8OES
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BU of 8oes by Molmil
MUC5B amino acids 26-1435 Three beads
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Mucin-5B
Authors:Khmelnitsky, L, Fass, D.
Deposit date:2023-03-12
Release date:2024-03-27
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Pulmonary Fibrosis Linked to Impaired Mucin 5B Supramolecular Assembly
To Be Published
8OER
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BU of 8oer by Molmil
MUC5B amino acids 26-1435
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Mucin-5B
Authors:Khmelnitsky, L, Fass, D.
Deposit date:2023-03-12
Release date:2024-03-27
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Pulmonary Fibrosis Linked to Impaired Mucin 5B Supramolecular Assembly
To Be Published
1GBM
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BU of 1gbm by Molmil
ALPHA-LYTIC PROTEASE WITH MET 190 REPLACED BY ALA COMPLEX WITH METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID
Descriptor: ALPHA-LYTIC PROTEASE, METHOXYSUCCINYL-ALA-ALA-PRO-PHENYLALANINE BORONIC ACID INHIBITOR, SULFATE ION
Authors:Mace, J.E, Agard, D.A.
Deposit date:1995-09-06
Release date:1996-01-29
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Kinetic and structural characterization of mutations of glycine 216 in alpha-lytic protease: a new target for engineering substrate specificity.
J.Mol.Biol., 254, 1995
8OMZ
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BU of 8omz by Molmil
Wide inward-open unliganded UraA in complex with a conformation-selective synthetic nanobody
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DECYL-BETA-D-MALTOPYRANOSIDE, PENTAETHYLENE GLYCOL, ...
Authors:Kuhn, B.T, Geertsma, E.R.
Deposit date:2023-03-31
Release date:2024-04-10
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Interdomain-linkers control conformational transitions in the SLC23 elevator transporter UraA.
Nat Commun, 15, 2024
1G76
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X-RAY STRUCTURE OF ESCHERICHIA COLI PYRIDOXINE 5'-PHOSPHATE OXIDASE COMPLEXED WITH PYRIDOXAL 5'-PHOSPHATE AT 2.0 A RESOLUTION
Descriptor: FLAVIN MONONUCLEOTIDE, PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Safo, M.K, Musayev, F.N, di Salvo, M.L, Schirch, V.
Deposit date:2000-11-09
Release date:2000-11-29
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:X-ray structure of Escherichia coli pyridoxine 5'-phosphate oxidase complexed with pyridoxal 5'-phosphate at 2.0 A resolution.
J.Mol.Biol., 310, 2001
1G78
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X-RAY STRUCTURE OF ESCHERICHIA COLI PYRIDOXINE 5'-PHOSPHATE OXIDASE COMPLEXED WITH PYRIDOXAL 5'-PHOSPHATE AT 2.0 A RESOLUTION
Descriptor: FLAVIN MONONUCLEOTIDE, PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Safo, M.K, Musayev, F.N, di Salvo, M.L, Schirch, V.
Deposit date:2000-11-09
Release date:2000-11-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:X-ray structure of Escherichia coli pyridoxine 5'-phosphate oxidase complexed with pyridoxal 5'-phosphate at 2.0 A resolution.
J.Mol.Biol., 310, 2001

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