1T6N
 
 | | Crystal structure of the N-terminal domain of human UAP56 | | Descriptor: | CITRATE ANION, Probable ATP-dependent RNA helicase | | Authors: | Zhao, R. | | Deposit date: | 2004-05-06 | | Release date: | 2004-08-31 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Crystal Structure of UAP56, a DExD/H-Box Protein Involved in Pre-mRNA Splicing and mRNA Export
Structure, 12, 2004
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421D
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6M0T
 | | Crystal Structure of Lysyl-tRNA Synthetase from Plasmodium falciparum complexed with L-lysine and Cladosporin derivative (CL-2) | | Descriptor: | (3R)-3-[(R)-[(2R,6S)-6-methyloxan-2-yl]-oxidanyl-methyl]-6,8-bis(oxidanyl)-3,4-dihydroisochromen-1-one, LYSINE, Lysine--tRNA ligase | | Authors: | Babbar, P, Sharma, A, Manickam, Y. | | Deposit date: | 2020-02-22 | | Release date: | 2021-04-21 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.68 Å) | | Cite: | Design, Synthesis, and Structural Analysis of Cladosporin-Based Inhibitors of Malaria Parasites.
Acs Infect Dis., 7, 2021
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5KNN
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2P7F
 | | The Novel Use of a 2',5'-Phosphodiester Linkage as a Reaction Intermediate at the Active Site of a Small Ribozyme | | Descriptor: | COBALT HEXAMMINE(III), Loop A ribozyme strand, Loop B S-turn strand, ... | | Authors: | Torelli, A.T, Krucinska, J, Wedekind, J.E. | | Deposit date: | 2007-03-20 | | Release date: | 2007-05-22 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | A comparison of vanadate to a 2'-5' linkage at the active site of a small ribozyme suggests a role for water in transition-state stabilization
Rna, 13, 2007
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2P7E
 | | Vanadate at the Active Site of a Small Ribozyme Suggests a Role for Water in Transition-State Stabilization | | Descriptor: | 3' substrate strand, octameric fragment, 5' substrate strand, ... | | Authors: | Torelli, A.T, Krucinska, J, Wedekind, J.E. | | Deposit date: | 2007-03-20 | | Release date: | 2007-05-22 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | A comparison of vanadate to a 2'-5' linkage at the active site of a small ribozyme suggests a role for water in transition-state stabilization
Rna, 13, 2007
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2P7D
 | | A Minimal, 'Hinged' Hairpin Ribozyme Construct Solved with Mimics of the Product Strands at 2.25 Angstroms Resolution | | Descriptor: | 3' substrate strand, octameric fragment, 5' substrate strand, ... | | Authors: | Torelli, A.T, Krucinska, J, Wedekind, J.E. | | Deposit date: | 2007-03-20 | | Release date: | 2007-05-22 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | A comparison of vanadate to a 2'-5' linkage at the active site of a small ribozyme suggests a role for water in transition-state stabilization
Rna, 13, 2007
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6DT8
 | | Bacteriophage N4 RNA polymerase II elongation complex 1 | | Descriptor: | DNA (5'-D(P*AP*CP*CP*CP*AP*CP*CP*AP*AP*AP*AP*A)-3'), RNA (5'-R(P*UP*GP*GP*UP*GP*G)-3'), RNAP1, ... | | Authors: | Molodtsov, V, Murakami, K.S. | | Deposit date: | 2018-06-15 | | Release date: | 2018-07-11 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Minimalism and functionality: Structural lessons from the heterodimeric N4 bacteriophage RNA polymerase II.
J. Biol. Chem., 293, 2018
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6DTA
 | | Bacteriophage N4 RNA polymerase II elongation complex 2 | | Descriptor: | DNA (5'-D(P*CP*CP*CP*AP*CP*CP*AP*AP*AP*AP*A)-3'), GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Molodtsov, V, Murakami, K.S. | | Deposit date: | 2018-06-15 | | Release date: | 2018-07-11 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.694 Å) | | Cite: | Minimalism and functionality: Structural lessons from the heterodimeric N4 bacteriophage RNA polymerase II.
J. Biol. Chem., 293, 2018
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1JZC
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1CX5
 | | ANTISENSE DNA/RNA HYBRID CONTAINING MODIFIED BACKBONE | | Descriptor: | 5'-D(*CP*GP*CP*GP*TP*T*(MMT)P*TP*GP*CP*GP*C), 5'-R(*GP*CP*GP*CP*AP*AP*AP*AP*CP*GP*CP*G) | | Authors: | Yang, X, Han, X, Cross, C, Sanghvi, Y, Gao, X. | | Deposit date: | 1999-08-28 | | Release date: | 1999-09-14 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | NMR structure of an antisense DNA.RNA hybrid duplex containing a 3'-CH(2)N(CH(3))-O-5' or an MMI backbone linker.
Biochemistry, 38, 1999
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6DT7
 | | Bacteriophage N4 RNA polymerase II and DNA complex | | Descriptor: | DNA (5'-D(P*CP*CP*AP*CP*CP*TP*GP*CP*A)-3'), RNAP1, RNAP2 | | Authors: | Molodtsov, V, Murakami, K.S. | | Deposit date: | 2018-06-15 | | Release date: | 2018-07-11 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Minimalism and functionality: Structural lessons from the heterodimeric N4 bacteriophage RNA polymerase II.
J. Biol. Chem., 293, 2018
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1T5I
 | | Crystal structure of the C-terminal domain of UAP56 | | Descriptor: | C_TERMINAL DOMAIN OF A PROBABLE ATP-DEPENDENT RNA HELICASE | | Authors: | Zhao, R, Green, M.R, Shen, J. | | Deposit date: | 2004-05-04 | | Release date: | 2004-08-31 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of UAP56, a "DEXD/H-box" protein involved in pre-mRNA splicing and mRNA export
Structure, 12, 2004
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3AY0
 | | Crystal structure of Methanocaldococcus jannaschii Trm5 in complex with adenosine | | Descriptor: | ADENOSINE, Uncharacterized protein MJ0883, ZINC ION | | Authors: | Goto-Ito, S, Ito, T, Hou, Y.M, Yokoyama, S. | | Deposit date: | 2011-04-21 | | Release date: | 2011-08-17 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (3.05 Å) | | Cite: | Differentiating analogous tRNA methyltransferases by fragments of the methyl donor.
Rna, 17, 2011
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4HVC
 | | Crystal structure of human prolyl-tRNA synthetase in complex with halofuginone and ATP analogue | | Descriptor: | 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, Bifunctional glutamate/proline--tRNA ligase, MAGNESIUM ION, ... | | Authors: | Zhou, H, Sun, L, Yang, X.L, Schimmel, P. | | Deposit date: | 2012-11-06 | | Release date: | 2013-01-02 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | ATP-directed capture of bioactive herbal-based medicine on human tRNA synthetase.
Nature, 494, 2012
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3WZI
 | | Crystal structure of AfCsx3 in complex with ssRNA | | Descriptor: | Uncharacterized protein AF_1864, ssRNA | | Authors: | Yuan, Y.A, Yan, X. | | Deposit date: | 2014-09-25 | | Release date: | 2015-07-15 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal structures of CRISPR-associated Csx3 reveal a manganese-dependent deadenylation exoribonuclease.
Rna Biol., 12, 2015
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4R8I
 | | High Resolution Structure of a Mirror-Image RNA Oligonucleotide Aptamer in Complex with the Chemokine CCL2 | | Descriptor: | C-C motif chemokine 2, Mirror-Image RNA Oligonucleotide Aptamer NOXE36, POTASSIUM ION, ... | | Authors: | Oberthuer, D, Achenbach, J, Gabdulkhakov, A, Falke, S, Buchner, K, Maasch, C, Rehders, D, Klussmann, S, Betzel, C. | | Deposit date: | 2014-09-02 | | Release date: | 2015-04-29 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Crystal structure of a mirror-image L-RNA aptamer (Spiegelmer) in complex with the natural L-protein target CCL2.
Nat Commun, 6, 2015
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1X9C
 | | An all-RNA Hairpin Ribozyme with mutation U39C | | Descriptor: | 5'-R(*CP*GP*GP*UP*GP*AP*GP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*CP*CP*(A2M)P*GP*UP*CP*CP*AP*CP*CP*G)-3', ... | | Authors: | Alam, S, Grum-Tokars, V, Krucinska, J, Kundracik, M.L, Wedekind, J.E. | | Deposit date: | 2004-08-20 | | Release date: | 2005-11-22 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.19 Å) | | Cite: | Conformational Heterogeneity at Position U37 of an All-RNA Hairpin Ribozyme with Implications for Metal Binding and the Catalytic Structure of the S-Turn.
Biochemistry, 44, 2005
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1X9K
 | | An all-RNA Hairpin Ribozyme with mutation U39C | | Descriptor: | 5'-R(*AP*AP*UP*AP*GP*AP*GP*AP*AP*GP*CP*GP*A)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*GP*CP*AP*GP*UP*CP*CP*UP*AP*UP*U)-3', ... | | Authors: | Alam, S, Grum-Tokars, V, Krucinska, J, Kundracik, M.L, Wedekind, J.E. | | Deposit date: | 2004-08-21 | | Release date: | 2005-11-22 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (3.17 Å) | | Cite: | Conformational Heterogeneity at Position U37 of an All-RNA Hairpin Ribozyme with Implications for Metal Binding and the Catalytic Structure of the S-Turn.
Biochemistry, 44, 2005
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1I2Y
 | | 1.66 A STRUCTURE OF A-DUPLEX WITH BULGED ADENOSINE, SPERMINE FORM | | Descriptor: | DNA/RNA (5'-R(*GP*CP*G)-D(P*AP*TP*AP*T)-R(P*AP*CP*GP*U)-3'), SPERMINE | | Authors: | Tereshko, V, Wallace, S, Usman, N, Wincott, F, Egli, M. | | Deposit date: | 2001-02-12 | | Release date: | 2001-04-21 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.66 Å) | | Cite: | X-ray crystallographic observation of "in-line" and "adjacent" conformations in a bulged self-cleaving RNA/DNA hybrid.
RNA, 7, 2001
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1I2X
 | | 2.4 A STRUCTURE OF A-DUPLEX WITH BULGED ADENOSINE, SPERMIDINE FORM | | Descriptor: | DNA/RNA (5'-R(*GP*CP*G)-D(P*AP*TP*AP*T)-R(P*AP*CP*GP*U)-3'), SPERMIDINE | | Authors: | Tereshko, V, Wallace, S, Usman, N, Wincott, F, Egli, M. | | Deposit date: | 2001-02-12 | | Release date: | 2001-04-21 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | X-ray crystallographic observation of "in-line" and "adjacent" conformations in a bulged self-cleaving RNA/DNA hybrid.
RNA, 7, 2001
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1RPU
 | | Crystal Structure of CIRV p19 bound to siRNA | | Descriptor: | 19 kDa protein, 5'-R(P*CP*GP*UP*AP*CP*GP*CP*GP*UP*CP*AP*CP*GP*CP*GP*UP*AP*CP*GP*UP*U)-3' | | Authors: | Vargason, J.M, Szittya, G, Burgyan, J, Hall, T.M.T. | | Deposit date: | 2003-12-03 | | Release date: | 2004-01-13 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Size selective recognition of siRNA by an RNA silencing suppressor
Cell(Cambridge,Mass.), 115, 2003
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3C46
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3C3L
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3C2P
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