8U5B
| |
7EFC
| 1.70 A cryo-EM structure of streptavidin | Descriptor: | BIOTIN, Streptavidin | Authors: | Hiraizumi, M, Yamashita, K, Nishizawa, T, Kotecha, A, Nureki, O. | Deposit date: | 2021-03-21 | Release date: | 2021-04-28 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (1.7 Å) | Cite: | 1.70 A cryo-EM structure of streptavidin using all frames (corresponding to 70 e/A^2 total dose) To Be Published
|
|
7EFD
| 1.77 A cryo-EM structure of Streptavidin using first 40 frames (corresponding to about 40 e/A^2 total dose) | Descriptor: | BIOTIN, Streptavidin | Authors: | Hiraizumi, M, Yamashita, K, Nishizawa, T, Kotecha, A, Nureki, O. | Deposit date: | 2021-03-21 | Release date: | 2021-04-28 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (1.77 Å) | Cite: | 1.77 A cryo-EM structure of Streptavidin using first 40 frames (corresponding to about 40e/A^2 total dose) To Be Published
|
|
2HL4
| Crystal structure analysis of human carbonic anhydrase II in complex with a benzenesulfonamide derivative | Descriptor: | CHLORIDE ION, Carbonic anhydrase 2, GLYCEROL, ... | Authors: | Di Fiore, A, Supuran, C.T, Winum, J.-Y, Montero, J.-L, Pedone, C, Scozzafava, A, De Simone, G. | Deposit date: | 2006-07-06 | Release date: | 2007-05-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Carbonic anhydrase inhibitors: binding of an antiglaucoma glycosyl-sulfanilamide derivative to human isoform II and its consequences for the drug design of enzyme inhibitors incorporating sugar moieties Bioorg.Med.Chem.Lett., 17, 2007
|
|
7E80
| Cryo-EM structure of the flagellar rod with hook and export apparatus from Salmonella | Descriptor: | Flagellar MS ring L1, Flagellar MS ring L2, Flagellar basal body rod protein FlgB, ... | Authors: | Tan, J.X, Chang, S.H, Wang, X.F, Xu, C.H, Zhou, Y, Zhang, X, Zhu, Y.Q. | Deposit date: | 2021-02-28 | Release date: | 2021-04-28 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.67 Å) | Cite: | Structural basis of assembly and torque transmission of the bacterial flagellar motor. Cell, 184, 2021
|
|
8U27
| Bcl-2-xL complexed with compound 35 | Descriptor: | Apoptosis regulator Bcl-2, Bcl-2-like protein 1 chimera, propan-2-yl {4-[(5S)-1-(4-bromobenzoyl)-5-phenyl-4,5-dihydro-1H-pyrazol-3-yl]phenyl}carbamate | Authors: | Rizo, J, Pan, Y.-Z. | Deposit date: | 2023-09-05 | Release date: | 2023-09-13 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural insights for selective disruption of Beclin 1 binding to Bcl-2. Commun Biol, 6, 2023
|
|
2HND
| Crystal Structure of K101E Mutant HIV-1 Reverse Transcriptase in Complex with Nevirapine | Descriptor: | 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Ren, J, Nichols, C.E, Stamp, A, Chamberlain, P.P, Stammers, D.K. | Deposit date: | 2006-07-12 | Release date: | 2006-09-05 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural insights into mechanisms of non-nucleoside drug resistance for HIV-1 reverse transcriptases mutated at codons 101 or 138. Febs J., 273, 2006
|
|
8TY1
| |
2HN8
| Structural characterization and oligomerization of PB1-F2, a pro-apoptotic influenza A virus protein | Descriptor: | Protein PB1-F2 | Authors: | Bruns, K, Studtrucker, N, Sharma, A, Fossen, T, Mitzner, D, Eissmann, A, Tessmer, U, Roder, R, Henklein, P, Wray, V, Schubert, U. | Deposit date: | 2006-07-12 | Release date: | 2006-11-07 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Structural characterization and oligomerization of PB1-F2, a pro-apoptotic influenza A virus protein. J.Biol.Chem., 282, 2007
|
|
8TZS
| Structure of human WLS | Descriptor: | Protein wntless homolog | Authors: | Qi, X, Hu, Q, Li, X. | Deposit date: | 2023-08-27 | Release date: | 2023-10-18 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.84 Å) | Cite: | Molecular basis of Wnt biogenesis, secretion, and Wnt7-specific signaling. Cell, 186, 2023
|
|
2HJP
| |
8TB7
| Cryo-EM Structure of GPR61- | Descriptor: | 6-{[(3,5-difluoropyridin-4-yl)methyl]amino}-N-(4-ethoxy-6-methylpyrimidin-2-yl)-2-methoxy-N-(2-methoxyethyl)pyridine-3-sulfonamide, Fab hinge-binding nanobody, Fab24 BAK5 heavy chain, ... | Authors: | Lees, J.A, Dias, J.M, Han, S. | Deposit date: | 2023-06-28 | Release date: | 2023-10-04 | Method: | ELECTRON MICROSCOPY (2.94 Å) | Cite: | An inverse agonist of orphan receptor GPR61 acts by a G protein-competitive allosteric mechanism. Nat Commun, 14, 2023
|
|
8TZP
| Structure of human Wnt7a bound to WLS and RECK | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, PALMITOLEIC ACID, Protein Wnt-7a, ... | Authors: | Qi, X, Hu, Q, Li, X. | Deposit date: | 2023-08-27 | Release date: | 2023-10-18 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.23 Å) | Cite: | Molecular basis of Wnt biogenesis, secretion, and Wnt7-specific signaling. Cell, 186, 2023
|
|
2HM1
| Crystal Structure of human beta-secretase (BACE) in the presence of an inhibitor (2) | Descriptor: | Beta-secretase 1, N-{(1S)-2-({(1S,2R)-1-(3,5-DIFLUOROBENZYL)-3-[(3-ETHYLBENZYL)AMINO]-2-HYDROXYPROPYL}AMINO)-2-OXO-1-[(PENTYLSULFONYL)METHYL]ETHYL}NICOTINAMIDE | Authors: | Benson, T.E, Prince, D.B, Tomasselli, A.G, Emmons, T.L, Paddock, D.J. | Deposit date: | 2006-07-10 | Release date: | 2007-01-23 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Design of potent inhibitors of human beta-secretase. Part 2. Bioorg.Med.Chem.Lett., 17, 2007
|
|
8U5Y
| human RADX trimer bound to ssDNA | Descriptor: | DNA (25-MER), RPA-related protein RADX | Authors: | Balakrishnan, S, Chazin, W.J. | Deposit date: | 2023-09-13 | Release date: | 2023-10-11 | Last modified: | 2023-10-18 | Method: | ELECTRON MICROSCOPY (3.01 Å) | Cite: | Structure of RADX and mechanism for regulation of RAD51 nucleofilaments. Biorxiv, 2023
|
|
2HMB
| THREE-DIMENSIONAL STRUCTURE OF RECOMBINANT HUMAN MUSCLE FATTY ACID-BINDING PROTEIN | Descriptor: | MUSCLE FATTY ACID BINDING PROTEIN, PALMITIC ACID | Authors: | Zanotti, G, Scapin, G, Spadon, P, Veerkamp, J.H, Sacchettini, J.C. | Deposit date: | 1992-09-11 | Release date: | 1994-01-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Three-dimensional structure of recombinant human muscle fatty acid-binding protein. J.Biol.Chem., 267, 1992
|
|
2HGL
| NMR structure of the first qRRM domain of human hnRNP F | Descriptor: | Heterogeneous nuclear ribonucleoprotein F | Authors: | Dominguez, C, Allain, F.H.-T. | Deposit date: | 2006-06-27 | Release date: | 2006-07-11 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | NMR structure of the three quasi RNA recognition motifs (qRRMs) of human hnRNP F and interaction studies with Bcl-x G-tract RNA: a novel mode of RNA recognition. Nucleic Acids Res., 34, 2006
|
|
2HOD
| Crystal Structure of Fragment D from Human Fibrinogen Complexed with Gly-hydroxyPro-Arg-Pro-amide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Fibrinogen alpha chain, ... | Authors: | Doolittle, R.F, Kollman, J.M, Chen, A, Pandi, L. | Deposit date: | 2006-07-14 | Release date: | 2007-05-29 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: |
|
|
7DWQ
| Photosystem I from a chlorophyll d-containing cyanobacterium Acaryochloris marina | Descriptor: | (6'R,11cis,11'cis,13cis,15cis)-4',5'-didehydro-5',6'-dihydro-beta,beta-carotene, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... | Authors: | Chen, J.H, Zhang, X, Shen, J.R. | Deposit date: | 2021-01-17 | Release date: | 2021-06-02 | Last modified: | 2021-10-20 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | A unique photosystem I reaction center from a chlorophyll d-containing cyanobacterium Acaryochloris marina. J Integr Plant Biol, 63, 2021
|
|
7DWB
| Human Pannexin1 model | Descriptor: | Pannexin-1 | Authors: | Zhang, S.S, Yang, M.J. | Deposit date: | 2021-01-17 | Release date: | 2021-05-26 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Structure of the full-length human Pannexin1 channel and insights into its role in pyroptosis. Cell Discov, 7, 2021
|
|
8THR
| Structure of the human vesicular monoamine transporter 2 (VMAT2) bound to tetrabenazine in an occluded conformation | Descriptor: | (3S,5R,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one, fluorescent protein mVenus,Synaptic vesicular amine transporter,GFP nano body,Synaptic vesicular amine transporter,Synaptic vesicular amine transporter | Authors: | Dalton, M.P, Coleman, J.A. | Deposit date: | 2023-07-17 | Release date: | 2023-10-25 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.12 Å) | Cite: | Structural mechanisms for VMAT2 inhibition by tetrabenazine. Elife, 12, 2024
|
|
7DZW
| Apo spike protein from SARS-CoV2 | Descriptor: | Spike glycoprotein | Authors: | Liu, Y, Soh, W.T, Li, S, Kishikawa, J, Hirose, M, Kato, T, Standley, D, Okada, M, Arase, H. | Deposit date: | 2021-01-26 | Release date: | 2021-06-02 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.45 Å) | Cite: | An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies. Cell, 184, 2021
|
|
2HO2
| |
7EJ1
| human voltage-gated potassium channel KV1.3 | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Potassium voltage-gated channel subfamily A member 3, Voltage-gated potassium channel subunit beta-2 | Authors: | Liu, S, Zhao, Y, Tian, C. | Deposit date: | 2021-04-01 | Release date: | 2021-06-09 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structures of wild-type and H451N mutant human lymphocyte potassium channel K V 1.3. Cell Discov, 7, 2021
|
|
7EJ2
| human voltage-gated potassium channel KV1.3 H451N mutant | Descriptor: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Potassium voltage-gated channel subfamily A member 3, Voltage-gated potassium channel subunit beta-2 | Authors: | Liu, S, Zhao, Y, Tian, C. | Deposit date: | 2021-04-01 | Release date: | 2021-06-09 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structures of wild-type and H451N mutant human lymphocyte potassium channel K V 1.3. Cell Discov, 7, 2021
|
|