PDB: 46200 resultsInfo pagesStatus searchChemie searchBIRD

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1WV6	X-ray structure of the A-decamer GCGTATACGC with a single 2'-O-butyl thymine in place of T6, Sr-form Descriptor: 5'-D(*GP*CP*GP*TP*AP*(2BT)P*AP*CP*GP*C)-3', STRONTIUM ION Authors: Egli, M, Minasov, G, Tereshko, V, Pallan, P.S, Teplova, M, Inamati, G.B, Lesnik, E.A, Owens, S.R, Ross, B.S, Prakash, T.P, Manoharam, M. Deposit date: 2004-12-11 Release date: 2005-06-28 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Probing the influence of stereoelectronic effects on the biophysical properties of oligonucleotides: comprehensive analysis of the RNA affinity, nuclease resistance, and crystal structure of ten 2'-O-ribonucleic acid modifications. Biochemistry, 44, 2005
2YB6	Native human Rad6 Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, UBIQUITIN-CONJUGATING ENZYME E2 B Authors: Hibbert, R.G, Sixma, T.K. Deposit date: 2011-03-02 Release date: 2011-04-20 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.5 Å) Cite: E3 Ligase Rad18 Promotes Monoubiquitination Rather Than Ubiquitin Chain Formation by E2 Enzyme Rad6. Proc.Natl.Acad.Sci.USA, 108, 2011
2L2L	Solution structure of the coiled-coil complex between MBD2 and p66alpha Descriptor: Methyl-CpG-binding domain protein 2, Transcriptional repressor p66-alpha Authors: Williams Jr, D.C, Scarsdale Jr, N. Deposit date: 2010-08-20 Release date: 2011-05-04 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: p66Alpha-MBD2 coiled-coil interaction and recruitment of Mi-2 are critical for globin gene silencing by the MBD2-NuRD complex. Proc.Natl.Acad.Sci.USA, 108, 2011
1WV5	X-ray structure of the A-decamer GCGTATACGC with a single 2'-o-butyl thymine in place of T6, Mg-form Descriptor: 5'-D(*GP*CP*GP*TP*AP*(2BT)P*AP*CP*GP*C)-3', MAGNESIUM ION Authors: Egli, M, Minasov, G, Tereshko, V, Pallan, P.S, Teplova, M, Inamati, G.B, Lesnik, E.A, Owens, S.R, Ross, B.S, Prakash, T.P, Manoharam, M. Deposit date: 2004-12-11 Release date: 2005-06-28 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Probing the influence of stereoelectronic effects on the biophysical properties of oligonucleotides: comprehensive analysis of the RNA affinity, nuclease resistance, and crystal structure of ten 2'-O-ribonucleic acid modifications. Biochemistry, 44, 2005
2YBF	Complex of Rad18 (Rad6 binding domain) with Rad6b Descriptor: BETA-MERCAPTOETHANOL, E3 UBIQUITIN-PROTEIN LIGASE RAD18, SODIUM ION, ... Authors: Hibbert, R.G, Sixma, T.K. Deposit date: 2011-03-08 Release date: 2011-04-20 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2 Å) Cite: E3 Ligase Rad18 Promotes Monoubiquitination Rather Than Ubiquitin Chain Formation by E2 Enzyme Rad6. Proc.Natl.Acad.Sci.USA, 108, 2011
5BS7	Structure of histone H3/H4 in complex with Spt2 Descriptor: Histone H3.2, Histone H4, Protein SPT2 homolog, ... Authors: Chen, S, Patel, D.J. Deposit date: 2015-06-01 Release date: 2015-07-08 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Structure-function studies of histone H3/H4 tetramer maintenance during transcription by chaperone Spt2. Genes Dev., 29, 2015
7DFY	Novel motif for left-handed G-quadruplex formation Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2xMotif2, POTASSIUM ION, ... Authors: Das, P, Winnerdy, F.R, Maity, A, Mechulam, Y, Phan, A.T. Deposit date: 2020-11-10 Release date: 2021-09-01 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.69 Å) Cite: A novel minimal motif for left-handed G-quadruplex formation. Chem.Commun.(Camb.), 57, 2021
6ETJ	HUMAN PFKFB3 IN COMPLEX WITH KAN0438241 Descriptor: 4-[[3-(5-fluoranyl-2-oxidanyl-phenyl)phenyl]sulfonylamino]-2-oxidanyl-benzoic acid, 6-O-phosphono-beta-D-fructofuranose, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3, ... Authors: Gustafsson, N.M.S, Lundback, T, Farnegardh, K, Groth, P, Wiitta, E, Jonsson, M, Hallberg, K, Pennisi, R, Huguet Ninou, A, Martinsson, J, Norstrom, C, Schultz, J, Andersson, M, Markova, N, Marttila, P, Norin, M, Olin, T, Helleday, T. Deposit date: 2017-10-26 Release date: 2018-11-07 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2.51 Å) Cite: Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination. Nat Commun, 9, 2018
8BNV	Crystal structure of Pif1 from Deferribacter desulfuricans in apo from Descriptor: AAA family ATPase, GLYCEROL, MAGNESIUM ION Authors: Rety, S, Chen, W.F, Xi, X.G. Deposit date: 2022-11-14 Release date: 2023-03-08 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.86 Å) Cite: Structural Studies of Pif1 Helicases from Thermophilic Bacteria. Microorganisms, 11, 2023
8BNX	Crystal structure of Pif1 from Deferribacter desulfuricans in complex with AMPPNP Descriptor: AAA family ATPase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER Authors: Rety, S, Chen, W.F, Xi, X.G. Deposit date: 2022-11-14 Release date: 2023-03-08 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (3.12 Å) Cite: Structural Studies of Pif1 Helicases from Thermophilic Bacteria. Microorganisms, 11, 2023
7ZCV	Rgg144 of Streptococcus pneumoniae Descriptor: Transcriptional regulator Authors: Wallis, R, Girija, U.V, Yesilkaya, H. Deposit date: 2022-03-29 Release date: 2022-06-01 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structure-function analysis for the development of peptide inhibitors for a Gram-positive quorum sensing system. Mol.Microbiol., 117, 2022
7Z21	BAF A12T bound to the lamin A/C Ig-fold domain Descriptor: Barrier-to-autointegration factor, N-terminally processed, CHLORIDE ION, ... Authors: Marcelot, A, Legrand, P, Zinn-Justin, S. Deposit date: 2022-02-25 Release date: 2022-08-24 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.629 Å) Cite: The BAF A12T mutation disrupts lamin A/C interaction, impairing robust repair of nuclear envelope ruptures in Nestor-Guillermo progeria syndrome cells. Nucleic Acids Res., 50, 2022
8BAT	Geobacter lovleyi NADAR Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Geobacter lovleyi NADAR Authors: Schuller, M, Ariza, A. Deposit date: 2022-10-11 Release date: 2023-07-12 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Molecular basis for the reversible ADP-ribosylation of guanosine bases. Mol.Cell, 83, 2023
8BAU	Phytophthora nicotianae var. parasitica NADAR in complex with ADP-ribose Descriptor: 1,2-ETHANEDIOL, NADAR domain-containing protein, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE Authors: Schuller, M, Ariza, A. Deposit date: 2022-10-11 Release date: 2023-07-12 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Molecular basis for the reversible ADP-ribosylation of guanosine bases. Mol.Cell, 83, 2023
5CW6	Structure of metal dependent enzyme DrBRCC36 Descriptor: DrBRCC36, ZINC ION Authors: Zeqiraj, E. Deposit date: 2015-07-27 Release date: 2015-09-16 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (3.193 Å) Cite: Higher-Order Assembly of BRCC36-KIAA0157 Is Required for DUB Activity and Biological Function. Mol.Cell, 59, 2015
1OB9	Holliday Junction Resolving Enzyme Descriptor: 1,2-ETHANEDIOL, FORMIC ACID, HOLLIDAY JUNCTION RESOLVASE Authors: Middleton, C.L, Parker, J.L, Richard, D.J, White, M.F, Bond, C.S. Deposit date: 2003-01-28 Release date: 2004-10-15 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Substrate Recognition and Catalysis by the Holliday Junction Resolving Enzyme Hje. Nucleic Acids Res., 32, 2004
7ZMO	Crystal structure of human RECQL5 helicase APO form in complex with engineered nanobody (Gluebody) G3-052 Descriptor: ATP-dependent DNA helicase Q5, Gluebody G3-052, SULFATE ION, ... Authors: Ye, M, Makola, M, Newman, J.A, Fairhead, M, MacLean, E, Krojer, T, Aitkenhead, H, Bountra, C, Gileadi, O, von Delft, F. Deposit date: 2022-04-19 Release date: 2022-06-22 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (3.75 Å) Cite: Gluebodies improve crystal reliability and diversity through transferable nanobody mutations that introduce constitutive crystal contacts To Be Published
7ZMV	Crystal structure of human RECQL5 helicase APO form in complex with engineered nanobody (Gluebody) G5-006 Descriptor: ATP-dependent DNA helicase Q5, Gluebody G5-006, SULFATE ION, ... Authors: Ye, M, Makola, M, Newman, J.A, Fairhead, M, MacLean, E, Krojer, T, Aitkenhead, H, Bountra, C, Gileadi, O, von Delft, F. Deposit date: 2022-04-19 Release date: 2022-06-22 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.002 Å) Cite: Gluebodies improve crystal reliability and diversity through transferable nanobody mutations that introduce constitutive crystal contacts To Be Published
7ZMT	Crystal structure of human RECQL5 helicase APO form in complex with engineered nanobody (Gluebody) G5-006 Descriptor: ATP-dependent DNA helicase Q5, Gluebody G5-006, ZINC ION Authors: Ye, M, Makola, M, Newman, J.A, Fairhead, M, MacLean, E, Krojer, T, Aitkenhead, H, Bountra, C, Gileadi, O, von Delft, F. Deposit date: 2022-04-19 Release date: 2022-06-22 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Gluebodies improve crystal reliability and diversity through transferable nanobody mutations that introduce constitutive crystal contacts To Be Published
7ZMP	Crystal structure of human RECQL5 helicase APO form in complex with engineered nanobody (Gluebody) G3-055 Descriptor: ATP-dependent DNA helicase Q5, Gluebody G3-055, ZINC ION Authors: Ye, M, Makola, M, Newman, J.A, Fairhead, M, MacLean, E, Krojer, T, Aitkenhead, H, Bountra, C, Gileadi, O, von Delft, F. Deposit date: 2022-04-19 Release date: 2022-06-22 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (3.626 Å) Cite: Gluebodies improve crystal reliability and diversity through transferable nanobody mutations that introduce constitutive crystal contacts To Be Published
7ZMR	Crystal structure of human RECQL5 helicase APO form in complex with engineered nanobody (Gluebody) G2*-011 Descriptor: ATP-dependent DNA helicase Q5, Gluebody G2*-011, SULFATE ION, ... Authors: Ye, M, Makola, M, Newman, J.A, Fairhead, M, MacLean, E, Krojer, T, Aitkenhead, H, Bountra, C, Gileadi, O, von Delft, F. Deposit date: 2022-04-19 Release date: 2022-06-22 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Gluebodies improve crystal reliability and diversity through transferable nanobody mutations that introduce constitutive crystal contacts To Be Published
7ZMQ	Crystal structure of human RECQL5 helicase APO form in complex with engineered nanobody (Gluebody) G2*-006 Descriptor: ATP-dependent DNA helicase Q5, Gluebody G2*-006, SULFATE ION, ... Authors: Ye, M, Makola, M, Newman, J.A, Fairhead, M, MacLean, E, Krojer, T, Aitkenhead, H, Bountra, C, Gileadi, O, von Delft, F. Deposit date: 2022-04-19 Release date: 2022-06-22 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Gluebodies improve crystal reliability and diversity through transferable nanobody mutations that introduce constitutive crystal contacts To Be Published
7ZML	Crystal structure of human RECQL5 helicase APO form in complex with engineered nanobody (Gluebody) G1-001 Descriptor: ATP-dependent DNA helicase Q5, Gluebody G1-001, SULFATE ION, ... Authors: Ye, M, Makola, M, Newman, J.A, Fairhead, M, MacLean, E, Krojer, T, Aitkenhead, H, Bountra, C, Gileadi, O, von Delft, F. Deposit date: 2022-04-19 Release date: 2022-06-22 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.79 Å) Cite: Gluebodies improve crystal reliability and diversity through transferable nanobody mutations that introduce constitutive crystal contacts To Be Published
7ZMM	Crystal structure of human RECQL5 helicase APO form in complex with engineered nanobody (Gluebody) G2-001 Descriptor: ATP-dependent DNA helicase Q5, Gluebody G2-001, ZINC ION Authors: Ye, M, Makola, M, Newman, J.A, Fairhead, M, MacLean, E, Krojer, T, Aitkenhead, H, Bountra, C, Gileadi, O, von Delft, F. Deposit date: 2022-04-19 Release date: 2022-06-22 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Gluebodies improve crystal reliability and diversity through transferable nanobody mutations that introduce constitutive crystal contacts To Be Published
7ZMN	Crystal structure of human RECQL5 helicase APO form in complex with engineered nanobody (Gluebody) G3-048 Descriptor: ATP-dependent DNA helicase Q5, Gluebody G3-048, SULFATE ION, ... Authors: Ye, M, Makola, M, Newman, J.A, Fairhead, M, MacLean, E, Krojer, T, Aitkenhead, H, Bountra, C, Gileadi, O, von Delft, F. Deposit date: 2022-04-19 Release date: 2022-06-22 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Gluebodies improve crystal reliability and diversity through transferable nanobody mutations that introduce constitutive crystal contacts To Be Published

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