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6IWH
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BU of 6iwh by Molmil
Crystal structure of rhesus macaque MHC class I molecule Mamu-B*05104 complexed with C14-GGGI lipopeptide
Descriptor: 1,2-ETHANEDIOL, Beta-2-microglobulin, C14-GGGI lipopeptide, ...
Authors:Yamamoto, Y, Morita, D, Sugita, M.
Deposit date:2018-12-05
Release date:2019-08-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Identification and Structure of an MHC Class I-Encoded Protein with the Potential to PresentN-Myristoylated 4-mer Peptides to T Cells.
J Immunol., 202, 2019
6P2C
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BU of 6p2c by Molmil
Structure of a nested set of N-terminally extended MHC I-peptides provides novel insights into antigen processing and presentation
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-8 alpha chain, ...
Authors:Li, L, Batliwala, M, Bouvier, M.
Deposit date:2019-05-21
Release date:2019-10-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.396 Å)
Cite:ERAP1 enzyme-mediated trimming and structural analyses of MHC I-bound precursor peptides yield novel insights into antigen processing and presentation.
J.Biol.Chem., 294, 2019
6J2F
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BU of 6j2f by Molmil
Crystal structure of bat (Pteropus Alecto) MHC class I Ptal-N*01:01 in complex with Hendra virus-derived peptide HeV2
Descriptor: HeV2, Ptal-N*01:01, beta-2 microglobulin
Authors:Lu, D, Liu, K.F, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, G.F, Liu, W.J.
Deposit date:2019-01-01
Release date:2019-09-18
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats.
Plos Biol., 17, 2019
6P2S
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BU of 6p2s by Molmil
Structure of a nested set of N-terminally extended MHC I-peptides provide novel insights into antigen processing and presentation
Descriptor: Beta-2-microglobulin, MHC I-peptide, MHC class I antigen
Authors:Li, L, Batliwala, M, Bouvier, M.
Deposit date:2019-05-22
Release date:2019-10-16
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:ERAP1 enzyme-mediated trimming and structural analyses of MHC I-bound precursor peptides yield novel insights into antigen processing and presentation.
J.Biol.Chem., 294, 2019
6J2I
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BU of 6j2i by Molmil
Crystal structure of bat (Pteropus Alecto) MHC class I Ptal-N*01:01 in complex with H17N10 influenza-like virus-derivrd peptide H17N10-NP
Descriptor: Beta-2-microglobulin, H17N10-NP, Ptal-N*01:01
Authors:Lu, D, Liu, K.F, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, G.F, Liu, W.J.
Deposit date:2019-01-01
Release date:2019-09-18
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats.
Plos Biol., 17, 2019
6IWG
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BU of 6iwg by Molmil
Crystal structure of rhesus macaque MHC class I molecule Mamu-B*05104 complexed with N-myristoylated 4-mer lipopeptide derived from SIV nef protein
Descriptor: 1,2-ETHANEDIOL, BORIC ACID, Beta-2-microglobulin, ...
Authors:Yamamoto, Y, Morita, D, Sugita, M.
Deposit date:2018-12-05
Release date:2019-08-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Identification and Structure of an MHC Class I-Encoded Protein with the Potential to PresentN-Myristoylated 4-mer Peptides to T Cells.
J Immunol., 202, 2019
6P2F
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BU of 6p2f by Molmil
Structure of a nested set of N-terminally extended MHC I-peptides provides novel insights into antigen processing and presentation
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-8 alpha chain, ...
Authors:Li, L, Batliwala, M, Bouvier, M.
Deposit date:2019-05-21
Release date:2019-10-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.482 Å)
Cite:ERAP1 enzyme-mediated trimming and structural analyses of MHC I-bound precursor peptides yield novel insights into antigen processing and presentation.
J.Biol.Chem., 294, 2019
6PBH
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BU of 6pbh by Molmil
Crystal Structure of HLA-A*68:01 in complex with NP145-156, a 12 mer influenza peptide
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, A-68 alpha chain, ...
Authors:Gras, S.
Deposit date:2019-06-13
Release date:2019-12-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Challenging immunodominance of influenza-specific CD8+T cell responses restricted by the risk-associated HLA-A*68:01 allomorph.
Nat Commun, 10, 2019
6JOZ
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BU of 6joz by Molmil
Crystal structure of BRLF peptide from EBV in complex with HLA-A1101.
Descriptor: ALA-THR-ILE-GLY-THR-ALA-MET-TYR-LYS, Beta-2-microglobulin, GLYCEROL, ...
Authors:Huan, X, Xiao, Z, Tadwal, V.S, Ren, E.C.
Deposit date:2019-03-25
Release date:2020-01-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Crystal structure of suboptimal viral fragments of Epstein Barr Virus Rta peptide-HLA complex that stimulate CD8 T cell response.
Sci Rep, 9, 2019
6P4A
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BU of 6p4a by Molmil
HyHEL10 Fab complexed with hen egg lysozyme carrying two mutations (HEL2x-rigid): R21Q and R73E
Descriptor: HyHEL10 Fab heavy chain, HyHEL10 Fab light chain, Lysozyme C
Authors:Langley, D.B, Christ, D.
Deposit date:2019-05-27
Release date:2020-05-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens.
Proc.Natl.Acad.Sci.USA, 117, 2020
6P64
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BU of 6p64 by Molmil
Alpha-beta TCR Binding to Neoantigen KQWLVWLFL Presented by HLA-A206
Descriptor: 302TIL TCR alpha chain, 302TIL TCR beta chain, Beta-2-microglobulin, ...
Authors:Devlin, J.R, Baker, B.M.
Deposit date:2019-05-31
Release date:2020-06-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:A T cell receptor peptide/MHC complex at 3.05 Angstrom resolution
To be Published
6P23
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BU of 6p23 by Molmil
Structure of a nested set of N-terminally extended MHC I-peptides provide novel insights into antigen processing presentation
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-8 alpha chain, ...
Authors:Li, L, Batliwala, M, Bouvier, M.
Deposit date:2019-05-20
Release date:2019-10-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.595 Å)
Cite:ERAP1 enzyme-mediated trimming and structural analyses of MHC I-bound precursor peptides yield novel insights into antigen processing and presentation.
J.Biol.Chem., 294, 2019
6JQ2
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BU of 6jq2 by Molmil
Crystal Structure of H2-Kb in complex with a DPAGT1 self-peptide
Descriptor: Beta-2-microglobulin, DPATG1 antigen SIIVFNLV, H-2 class I histocompatibility antigen, ...
Authors:Bai, P, Yin, L.
Deposit date:2019-03-28
Release date:2020-04-01
Last modified:2021-02-17
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy.
Oncoimmunology, 10, 2021
6JQ3
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BU of 6jq3 by Molmil
Crystal Structure of H2-Kb in complex with a DPAGT1 mutant peptide
Descriptor: Beta-2-microglobulin, DPAGT1 mutant antigen SIIVFNLL, H-2 class I histocompatibility antigen, ...
Authors:Bai, P, Zhou, Q, Wei, P, Yin, L.
Deposit date:2019-03-28
Release date:2020-05-06
Last modified:2021-02-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy.
Oncoimmunology, 10, 2021
6JXR
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BU of 6jxr by Molmil
Structure of human T cell receptor-CD3 complex
Descriptor: T cell receptor alpha variable 12-3,Possible J 11 gene segment,T cell receptor alpha constant, T cell receptor beta variable 6-5,M1-specific T cell receptor beta chain,T cell receptor beta constant 2, T-cell surface glycoprotein CD3 delta chain, ...
Authors:Dong, D, Zheng, L, Lin, J, Zhu, Y, Li, N, Zhang, B, Xie, S, Zheng, J, Wang, Y, Gao, N, Huang, Z.
Deposit date:2019-04-24
Release date:2019-09-11
Last modified:2020-09-16
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of assembly of the human T cell receptor-CD3 complex.
Nature, 573, 2019
6JTN
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BU of 6jtn by Molmil
Crystal structure of HLA-C08 in complex with a tumor mut10m peptide
Descriptor: 10-mer peptide, Beta-2-microglobulin, HLA class I antigen, ...
Authors:Bai, P, Zhou, Q, Wei, P, Yin, L.
Deposit date:2019-04-11
Release date:2020-04-15
Last modified:2021-02-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy.
Oncoimmunology, 10, 2021
6PA1
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BU of 6pa1 by Molmil
Killer cell immunoglobulin-like receptor 2DL2 in complex with HLA-C*07:02
Descriptor: ARG-TYR-ARG-PRO-GLY-THR-VAL-ALA-LEU, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Moradi, S, Rossjohn, J, Vivian, J.P.
Deposit date:2019-06-11
Release date:2020-12-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Structural plasticity of KIR2DL2 and KIR2DL3 enables altered docking geometries atop HLA-C.
Nat Commun, 12, 2021
6K7T
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BU of 6k7t by Molmil
Crystal structure of bat (Pteropus Alecto) MHC class I Ptal-N*01:01 in complex with Hendra virus-derived peptide HeV1--human beta-2 microglobulin
Descriptor: Beta-2-microglobulin, HeV1, MHC class I antigen
Authors:Lu, D, Liu, K.F, Zhang, D, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, F.G, Liu, W.J.
Deposit date:2019-06-08
Release date:2019-11-06
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats.
Plos Biol., 17, 2019
6PAG
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BU of 6pag by Molmil
Killer cell immunoglobulin-like receptor 2DL3 in complex with HLA-C*07:02
Descriptor: ARG-TYR-ARG-PRO-GLY-THR-VAL-ALA-LEU, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Moradi, S, Rossjohn, J, Vivian, J.P.
Deposit date:2019-06-11
Release date:2020-12-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Structural plasticity of KIR2DL2 and KIR2DL3 enables altered docking geometries atop HLA-C.
Nat Commun, 12, 2021
6JTP
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BU of 6jtp by Molmil
Crystal structure of HLA-C08 in complex with a tumor mut9m peptide
Descriptor: 9-mer peptide, Beta-2-microglobulin, HLA class I antigen, ...
Authors:Bai, P, Zhou, Q, Wei, P, Lei, Y.
Deposit date:2019-04-11
Release date:2020-04-15
Last modified:2021-02-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy.
Oncoimmunology, 10, 2021
6ILC
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BU of 6ilc by Molmil
CRYSTAL STRUCTURE OF BAT MHC CLASS I PTAL-N*01:01 FOR 2.2 ANGSTROM
Descriptor: Beta-2-microglobulin, HEV-1, MHC class I antigen
Authors:Qu, Z.H, Zhang, N.Z, Xia, C.
Deposit date:2018-10-17
Release date:2019-07-24
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and Peptidome of the Bat MHC Class I Molecule Reveal a Novel Mechanism Leading to High-Affinity Peptide Binding.
J Immunol., 202, 2019
6Q3K
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BU of 6q3k by Molmil
Engineered Human HLA_A2 MHC Class I molecule in complex with NV9 peptide
Descriptor: ASN-LEU-VAL-PRO-MET-VAL-ALA-THR-VAL, Beta-2-microglobulin, COBALT (II) ION, ...
Authors:Meijers, R, Anjanappa, R, Springer, S, Garcia-Alai, M.
Deposit date:2018-12-04
Release date:2019-07-24
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Engineered Human HLA_A2MHC Class I molecule in complex with NV9 peptide
Sci Immunol, 2019
6PYV
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BU of 6pyv by Molmil
Crystal Structure of HLA-B*2703-P47G in complex with LRN, a self-peptide
Descriptor: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-2703 alpha chain, ...
Authors:Gras, S.
Deposit date:2019-07-31
Release date:2019-11-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Allelic association with ankylosing spondylitis fails to correlate with human leukocyte antigen B27 homodimer formation.
J.Biol.Chem., 294, 2019
6PTE
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BU of 6pte by Molmil
Crystal Structure of ILNAMITKI peptide bound to HLA-A2
Descriptor: Beta-2-microglobulin, GLYCEROL, HAUS augmin-like complex subunit 3, ...
Authors:Smith, A.R, Arbuiso, A, Keller, G.L.J, Baker, B.M.
Deposit date:2019-07-15
Release date:2019-09-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Structure Based Prediction of Neoantigen Immunogenicity.
Front Immunol, 10, 2019
6PUK
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BU of 6puk by Molmil
Structure of human MAIT A-F7 TCR in complex with human MR1-JYM72
Descriptor: 1,2-dideoxy-1-{2,6-dioxo-5-[(1E)-3-oxobut-1-en-1-yl]-1,2,3,6-tetrahydropyrimidin-4-yl}-D-ribo-hexitol, ACETATE ION, Beta-2-microglobulin, ...
Authors:Awad, W, Keller, A.N, Rossjohn, J.
Deposit date:2019-07-18
Release date:2020-02-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:The molecular basis underpinning the potency and specificity of MAIT cell antigens.
Nat.Immunol., 21, 2020

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