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6KDK
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BU of 6kdk by Molmil
HIV-1 reverse transcriptase with Q151M/Y115F/F116Y:DNA:dCTP ternary complex
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA/RNA (38-MER), GLYCEROL, ...
Authors:Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K.
Deposit date:2019-07-02
Release date:2020-03-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine.
Sci Rep, 10, 2020
4X4G
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BU of 4x4g by Molmil
RADIATION DAMAGE TO THE NUCLEOPROTEIN COMPLEX C.Esp1396I: DOSE (DWD) 26.8 MGy
Descriptor: 35-MER DNA, Regulatory protein
Authors:Bury, C.S, McGeehan, J.E, Garman, E.F.
Deposit date:2014-12-02
Release date:2015-03-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Radiation damage to nucleoprotein complexes in macromolecular crystallography.
J.Synchrotron Radiat., 22, 2015
7KWO
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BU of 7kwo by Molmil
rFVIIIFc-VWF-XTEN (BIVV001)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COPPER (II) ION, ...
Authors:Fuller, J.R, Batchelor, J.D.
Deposit date:2020-12-01
Release date:2021-03-03
Last modified:2024-10-16
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Molecular determinants of the factor VIII/von Willebrand factor complex revealed by BIVV001 cryo-electron microscopy.
Blood, 137, 2021
1IH1
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BU of 1ih1 by Molmil
Crystal Structure of the B-DNA Hexamer GGCGCC with Cobalt Hexamine Resolved to 2.0 Angstroms
Descriptor: 5'-D(*GP*GP*CP*GP*CP*C)-3', COBALT HEXAMMINE(III), MAGNESIUM ION
Authors:Vargason, J.M, Henderson, K, Ho, P.S.
Deposit date:2001-04-18
Release date:2001-06-18
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:A crystallographic map of the transition from B-DNA to A-DNA.
Proc.Natl.Acad.Sci.USA, 98, 2001
8HSH
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BU of 8hsh by Molmil
Thermus thermophilus RNA polymerase coreenzyme
Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Murayama, Y, Ehara, H, Sekine, S.
Deposit date:2022-12-19
Release date:2023-05-03
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis of the transcription termination factor Rho engagement with transcribing RNA polymerase from Thermus thermophilus.
Sci Adv, 9, 2023
8HSG
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BU of 8hsg by Molmil
Thermus thermophilus RNA polymerase elongation complex
Descriptor: DNA (27-MER), DNA (37-MER), DNA-directed RNA polymerase subunit alpha, ...
Authors:Murayama, Y, Ehara, H, Sekine, S.
Deposit date:2022-12-19
Release date:2023-05-03
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis of the transcription termination factor Rho engagement with transcribing RNA polymerase from Thermus thermophilus.
Sci Adv, 9, 2023
4WRF
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BU of 4wrf by Molmil
Crystal Structure of Surfactant Protein-A DEDN Mutant (E171D/P175E/R197N/K203D) Complexed with Mannose
Descriptor: CALCIUM ION, CHLORIDE ION, HEXANE-1,6-DIOL, ...
Authors:Rynkiewicz, M.J, Wu, H, Cafarella, T.R, Nikolaidis, N.M, Head, J.F, Seaton, B.A, McCormack, F.X.
Deposit date:2014-10-23
Release date:2016-02-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Differential ligand binding specificities of the pulmonary collectins are determined by the conformational freedom of a surface loop
To be published
6KH5
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BU of 6kh5 by Molmil
Design and crystal structure of protein MOFs with ferritin nanocages as linkers and nickel clusters as nodes
Descriptor: FE (III) ION, Ferritin, NICKEL (II) ION
Authors:Gu, C, Chen, H, Wang, Y, Zhang, T, Wang, H, Zhao, G.
Deposit date:2019-07-12
Release date:2020-01-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.294 Å)
Cite:Structural Insight into Binary Protein Metal-Organic Frameworks with Ferritin Nanocages as Linkers and Nickel Clusters as Nodes.
Chemistry, 26, 2020
8IAH
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BU of 8iah by Molmil
Structure of mammalian spectrin-actin junctional complex of membrane skeleton, State I, Global map
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ...
Authors:Li, N, Chen, S, Gao, N.
Deposit date:2023-02-08
Release date:2023-05-03
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis of membrane skeleton organization in red blood cells.
Cell, 186, 2023
2J4S
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BU of 2j4s by Molmil
P450 BM3 heme domain in complex with DMSO
Descriptor: BIFUNCTIONAL P-450:NADPH-P450 REDUCTASE, DI(HYDROXYETHYL)ETHER, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Kuper, J, Tuck-Seng, W, Roccatano, D, Wilmanns, M, Schwaneberg, U.
Deposit date:2006-09-05
Release date:2007-05-15
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Understanding a Mechanism of Organic Cosolvent Inactivation in Heme Monooxygenase P450 Bm-3.
J.Am.Chem.Soc., 129, 2007
8HSL
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BU of 8hsl by Molmil
Thermus thermophilus RNA polymerase bound with an inverted Rho hexamer
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase subunit alpha, ...
Authors:Murayama, Y, Ehara, H, Sekine, S.
Deposit date:2022-12-19
Release date:2023-05-03
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Structural basis of the transcription termination factor Rho engagement with transcribing RNA polymerase from Thermus thermophilus.
Sci Adv, 9, 2023
7BEL
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BU of 7bel by Molmil
Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in a ternary complex with COVOX-88 and COVOX-45 Fabs
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, COVOX-45 heavy chain, ...
Authors:Zhou, D, Zhao, Y, Ren, J, Stuart, D.
Deposit date:2020-12-23
Release date:2021-03-03
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:The antigenic anatomy of SARS-CoV-2 receptor binding domain.
Cell, 184, 2021
4WGL
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BU of 4wgl by Molmil
Crystal structure of a GroEL D83A/R197A double mutant
Descriptor: 60 kDa chaperonin
Authors:Yang, D, Fei, X, LaRonde, N.A, Beckett, D, Lund, P.A, Lorimer, G.H.
Deposit date:2014-09-19
Release date:2015-09-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.13 Å)
Cite:Crystal structure of a GroEL D83A/R197A double mutant
To Be Published
7KZQ
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BU of 7kzq by Molmil
Structure of the human Fanconi anaemia Core-ID complex
Descriptor: E3 ubiquitin-protein ligase FANCL, Fanconi anemia core complex-associated protein 100, Fanconi anemia core complex-associated protein 20, ...
Authors:Wang, S.L, Pavletich, N.P.
Deposit date:2020-12-10
Release date:2021-03-10
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structure of the FA core ubiquitin ligase closing the ID clamp on DNA.
Nat.Struct.Mol.Biol., 28, 2021
7KZR
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BU of 7kzr by Molmil
Structure of the human Fanconi Anaemia Core-UBE2T-ID complex
Descriptor: E3 ubiquitin-protein ligase FANCL, Fanconi anemia core complex-associated protein 100, Fanconi anemia core complex-associated protein 20, ...
Authors:Wang, S.L, Pavletich, N.P.
Deposit date:2020-12-10
Release date:2021-03-10
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structure of the FA core ubiquitin ligase closing the ID clamp on DNA.
Nat.Struct.Mol.Biol., 28, 2021
4WJO
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BU of 4wjo by Molmil
Crystal Structure of SUMO1 in complex with PML
Descriptor: Protein PML, Small ubiquitin-related modifier 1
Authors:Cappadocia, L, Mascle, X.H, Bourdeau, V, Tremblay-Belzile, S, Chaker-Margot, M, Lussier-Price, M, Wada, J, Sakaguchi, K, Aubry, M, Ferbeyre, G, Omichinski, J.G.
Deposit date:2014-10-01
Release date:2014-12-31
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Structural and Functional Characterization of the Phosphorylation-Dependent Interaction between PML and SUMO1.
Structure, 23, 2015
1J8T
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BU of 1j8t by Molmil
Catalytic Domain of Human Phenylalanine Hydroxylase Fe(II)
Descriptor: FE (II) ION, PHENYLALANINE-4-HYDROXYLASE
Authors:Andersen, O.A, Flatmark, T, Hough, E.
Deposit date:2001-05-22
Release date:2002-05-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:High resolution crystal structures of the catalytic domain of human phenylalanine hydroxylase in its catalytically active Fe(II) form and binary complex with tetrahydrobiopterin.
J.Mol.Biol., 314, 2001
4WSS
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BU of 4wss by Molmil
The crystal structure of hemagglutinin form A/chicken/New York/14677-13/1998 in complex with LSTa
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Yang, H, Carney, P.J, Chang, J.C, Villanueva, J.M, Stevens, J.
Deposit date:2014-10-28
Release date:2015-02-25
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure and receptor binding preferences of recombinant hemagglutinins from avian and human h6 and h10 influenza a virus subtypes.
J.Virol., 89, 2015
4WSV
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BU of 4wsv by Molmil
The crystal structure of hemagglutinin from A/Taiwan/1/2013 in complex with 6'SLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ...
Authors:Yang, H, Carney, P.J, Chang, J.C, Villanueva, J.M, Stevens, J.
Deposit date:2014-10-28
Release date:2015-02-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure and receptor binding preferences of recombinant hemagglutinins from avian and human h6 and h10 influenza a virus subtypes.
J.Virol., 89, 2015
6KMV
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BU of 6kmv by Molmil
caspase-11 C254A P22/P10 in complex with mouse GSDMD-C domain
Descriptor: Caspase-4, Gasdermin-D
Authors:Ding, J, Sun, Q.
Deposit date:2019-08-01
Release date:2020-03-11
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis.
Cell, 180, 2020
4WJU
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BU of 4wju by Molmil
Crystal structure of Rsa4 from Saccharomyces cerevisiae
Descriptor: GLYCEROL, Ribosome assembly protein 4
Authors:Holdermann, I, Bassler, J, Hurt, E, Sinning, I.
Deposit date:2014-10-01
Release date:2014-11-19
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A network of assembly factors is involved in remodeling rRNA elements during preribosome maturation.
J.Cell Biol., 207, 2014
6DV5
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BU of 6dv5 by Molmil
Oligomeric complex of a Hsp27 24-mer at 3.6 A resolution
Descriptor: Heat shock protein beta-1
Authors:Aguda, A.H, Brayer, G.D.
Deposit date:2018-06-22
Release date:2019-06-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.58 Å)
Cite:Structure-Guided Discovery of Ivermectin as an Inhibitor of Heat Shock Protein-27 Phosphorylation and Depolymerization.
To Be Published
6T72
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BU of 6t72 by Molmil
Structure of the RsaA N-terminal domain bound to LPS
Descriptor: 4-acetamido-4,6-dideoxy-alpha-D-mannopyranose-(1-3)-4-acetamido-4,6-dideoxy-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-3)-4-acetamido-4,6-dideoxy-alpha-D-mannopyranose-(1-3)-4-acetamido-4,6-dideoxy-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-3)-4-acetamido-4,6-dideoxy-alpha-D-mannopyranose-(1-3)-4-acetamido-4,6-dideoxy-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-3)-4-acetamido-4,6-dideoxy-alpha-D-mannopyranose-(1-3)-4-acetamido-4,6-dideoxy-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose, CALCIUM ION, S-layer protein
Authors:von Kuegelgen, A, Bharat, T.A.M.
Deposit date:2019-10-21
Release date:2020-01-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:In Situ Structure of an Intact Lipopolysaccharide-Bound Bacterial Surface Layer.
Cell, 180, 2020
4WPD
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BU of 4wpd by Molmil
X-ray Crystal Structure of CYP119 complexed with 4-(4-flourophenyl)-1H-imidazole
Descriptor: 4-(4-fluorophenyl)-1H-imidazole, Cytochrome P450 119, PROTOPORPHYRIN IX CONTAINING FE
Authors:Madrona, Y.
Deposit date:2014-10-17
Release date:2015-02-18
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:TWO DIMENTIONAL NMR AND X-RAY ANALYSIS OF CYP119 LIGAND DEPENDENT CONFORMATIONAL DYNAMICS
To Be Published
2JE0
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BU of 2je0 by Molmil
Crystal Structure of pp32
Descriptor: ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER A, GLYCEROL
Authors:Huyton, T, Wolberger, C.
Deposit date:2007-01-12
Release date:2007-06-26
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Crystal Structure of the Tumor Suppressor Protein Pp32 (Anp32A): Structural Insights Into Anp32 Family of Proteins.
Protein Sci., 16, 2007

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