8TP9
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![BU of 8tp9 by Molmil](/molmil-images/mine/8tp9) | H2 hemagglutinin (A/Singapore/1/1957) in complex with medial-junction-targeting Fab 2-2-1G06 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 2-2-1G06, ... | Authors: | Yang, Y.R, Han, J, Perrett, H.R, Ward, A.B. | Deposit date: | 2023-08-04 | Release date: | 2023-10-11 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Immune memory shapes human polyclonal antibody responses to H2N2 vaccination. Biorxiv, 2023
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8TPA
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![BU of 8tpa by Molmil](/molmil-images/mine/8tpa) | H1 hemagglutinin (NC99) in complex with medial-junction-targeting Fab 2-2-1G06 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of Fab 2-2-1G06, ... | Authors: | Yang, Y.R, Han, J, Perrett, H.R, Ward, A.B. | Deposit date: | 2023-08-04 | Release date: | 2023-10-11 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Immune memory shapes human polyclonal antibody responses to H2N2 vaccination. Biorxiv, 2023
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2H2C
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![BU of 2h2c by Molmil](/molmil-images/mine/2h2c) | Crystal Structure of ZO-1 PDZ1 Bound to a Phage-Derived Ligand (WRRTTWV) | Descriptor: | Tight junction protein ZO-1 | Authors: | Appleton, B.A, Zhang, Y, Wu, P, Yin, J.P, Hunziker, W, Skelton, N.J, Sidhu, S.S, Wiesmann, C. | Deposit date: | 2006-05-18 | Release date: | 2006-06-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Comparative structural analysis of the Erbin PDZ domain and the first PDZ domain of ZO-1. Insights into determinants of PDZ domain specificity. J.Biol.Chem., 281, 2006
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2H2B
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![BU of 2h2b by Molmil](/molmil-images/mine/2h2b) | Crystal Structure of ZO-1 PDZ1 Bound to a Phage-Derived Ligand (WRRTTYL) | Descriptor: | ACETIC ACID, Tight junction protein ZO-1 | Authors: | Appleton, B.A, Zhang, Y, Wu, P, Yin, J.P, Hunziker, W, Skelton, N.J, Sidhu, S.S, Wiesmann, C. | Deposit date: | 2006-05-18 | Release date: | 2006-06-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Comparative structural analysis of the Erbin PDZ domain and the first PDZ domain of ZO-1. Insights into determinants of PDZ domain specificity. J.Biol.Chem., 281, 2006
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2H3M
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![BU of 2h3m by Molmil](/molmil-images/mine/2h3m) | Crystal Structure of ZO-1 PDZ1 | Descriptor: | SULFATE ION, Tight junction protein ZO-1 | Authors: | Appleton, B.A, Zhang, Y, Wu, P, Yin, J.P, Hunziker, W, Skelton, N.J, Sidhu, S.S, Wiesmann, C. | Deposit date: | 2006-05-22 | Release date: | 2006-06-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Comparative structural analysis of the Erbin PDZ domain and the first PDZ domain of ZO-1. Insights into determinants of PDZ domain specificity. J.Biol.Chem., 281, 2006
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1JIM
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![BU of 1jim by Molmil](/molmil-images/mine/1jim) | |
2H5X
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![BU of 2h5x by Molmil](/molmil-images/mine/2h5x) | RuvA from Mycobacterium tuberculosis | Descriptor: | GLYCEROL, Holliday junction ATP-dependent DNA helicase ruvA | Authors: | Prabu, J.R, Thamotharan, S, Khanduja, J.S, Alipio, E.Z, Kim, C.Y, Waldo, G.S, Terwilliger, T.C, Segelke, B, Lekin, T, Toppani, D, Hung, L.W, Yu, M, Bursey, E, Muniyappa, K, Chandra, N.R, Vijayan, M. | Deposit date: | 2006-05-28 | Release date: | 2006-08-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of Mycobacterium tuberculosis RuvA, a protein involved in recombination. ACTA CRYSTALLOGR.,SECT.F, 62, 2006
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6IWY
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![BU of 6iwy by Molmil](/molmil-images/mine/6iwy) | |
6IZ2
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![BU of 6iz2 by Molmil](/molmil-images/mine/6iz2) | |
2NPZ
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![BU of 2npz by Molmil](/molmil-images/mine/2npz) | Crystal structure of junctioned hairpin ribozyme incorporating synthetic propyl linker | Descriptor: | 5'-R(*CP*GP*GP*UP*GP*AP*GP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', 5'-R(*UP*CP*CP*CP*AP*GP*UP*CP*CP*AP*CP*CP*G)-3', ... | Authors: | MacElrevey, C, Krucinska, J, Wedekind, J.E. | Deposit date: | 2006-10-30 | Release date: | 2007-08-14 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | A posteriori design of crystal contacts to improve the X-ray diffraction properties of a small RNA enzyme. Acta Crystallogr.,Sect.D, 63, 2007
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2K7M
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![BU of 2k7m by Molmil](/molmil-images/mine/2k7m) | Structure of the Connexin40 Carboxyl terminal Domain | Descriptor: | Gap junction alpha-5 protein | Authors: | Bouvier, D, Spagnol, G, Kieken, F, Vitrac, H, Kellezi, A, Forge, V. | Deposit date: | 2008-08-14 | Release date: | 2009-07-28 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Characterization of the structure and intermolecular interactions between the connexin40 and connexin43 carboxyl-terminal and cytoplasmic loop domains. J.Biol.Chem., 284, 2009
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4X2Y
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![BU of 4x2y by Molmil](/molmil-images/mine/4x2y) | Crystal structure of a chimeric Murine Norovirus NS6 protease (inactive C139A mutant) in which the P4-P4 prime residues of the cleavage junction in the extended C-terminus have been replaced by the corresponding residues from the NS2-3 junction. | Descriptor: | NS6 Protease,NS6 Protease | Authors: | Leen, E.N, Pfeil, M.-P, Fernandes, H, Curry, S. | Deposit date: | 2014-11-27 | Release date: | 2015-02-18 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.417 Å) | Cite: | Structure determination of Murine Norovirus NS6 proteases with C-terminal extensions designed to probe protease-substrate interactions. Peerj, 3, 2015
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8UXX
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![BU of 8uxx by Molmil](/molmil-images/mine/8uxx) | Arp2/3 branch junction complex, BeFx state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | Authors: | Chavali, S.S, Chou, S.Z, Sindelar, C.V. | Deposit date: | 2023-11-11 | Release date: | 2024-01-31 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex. Nat Commun, 15, 2024
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2NPY
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![BU of 2npy by Molmil](/molmil-images/mine/2npy) | Crystal Structure of a junctioned hairpin ribozyme incorporating 9atom linker and 2'-deoxy 2'-amino U at A-1 | Descriptor: | 2-[2-(2-HYDROXYETHOXY)ETHOXY]ETHYL DIHYDROGEN PHOSPHATE, 5'-R(*CP*GP*GP*UP*GP*AP*GP*AP*AP*GP*GP*G)-3', 5'-R(*GP*GP*CP*AP*GP*AP*GP*AP*AP*AP*CP*AP*CP*AP*CP*GP*A)-3', ... | Authors: | MacElrevey, C, Krucinska, J, Wedekind, J.E. | Deposit date: | 2006-10-30 | Release date: | 2007-08-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | A posteriori design of crystal contacts to improve the X-ray diffraction properties of a small RNA enzyme. Acta Crystallogr.,Sect.D, 63, 2007
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4WCF
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![BU of 4wcf by Molmil](/molmil-images/mine/4wcf) | Trypanosoma brucei PTR1 in complex with inhibitor 9 | Descriptor: | 3-(5-amino-1,3,4-thiadiazol-2-yl)pyridin-4-amine, ACETATE ION, GLYCEROL, ... | Authors: | Mangani, S, Di Pisa, F, Pozzi, C. | Deposit date: | 2014-09-04 | Release date: | 2015-09-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery. ACS Omega, 2, 2017
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4WCD
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![BU of 4wcd by Molmil](/molmil-images/mine/4wcd) | Trypanosoma brucei PTR1 in complex with inhibitor 10 | Descriptor: | 5-(1H-benzotriazol-6-yl)-1,3,4-thiadiazol-2-amine, ACETATE ION, GLYCEROL, ... | Authors: | Mangani, S, Di Pisa, F, Pozzi, C. | Deposit date: | 2014-09-04 | Release date: | 2015-09-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery. ACS Omega, 2, 2017
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8UZ1
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![BU of 8uz1 by Molmil](/molmil-images/mine/8uz1) | Straight actin filament from Arp2/3 branch junction sample (ADP-BeFx) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ... | Authors: | Chavali, S.S, Chou, S.Z, Sindelar, C.V. | Deposit date: | 2023-11-14 | Release date: | 2024-01-31 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex. Nat Commun, 15, 2024
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8UXW
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![BU of 8uxw by Molmil](/molmil-images/mine/8uxw) | Arp2/3 branch junction complex, ADP state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | Authors: | Chavali, S.S, Chou, S.Z, Sindelar, C.V. | Deposit date: | 2023-11-11 | Release date: | 2024-01-31 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Cryo-EM structures reveal how phosphate release from Arp3 weakens actin filament branches formed by Arp2/3 complex. Nat Commun, 15, 2024
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2W19
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![BU of 2w19 by Molmil](/molmil-images/mine/2w19) | Non-covalent complex between dahp synthase and chorismate mutase from Mycobacterium tuberculosis | Descriptor: | 3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE AROG, CHORISMATE MUTASE, GLYCEROL, ... | Authors: | Okvist, M, Sasso, S, Roderer, K, Gamper, M, Codoni, G, Krengel, U, Kast, P. | Deposit date: | 2008-10-16 | Release date: | 2009-07-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structure and Function of a Complex between Chorismate Mutase and Dahp Synthase: Efficiency Boost for the Junior Partner. Embo J., 28, 2009
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2LL2
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![BU of 2ll2 by Molmil](/molmil-images/mine/2ll2) | Structure of the Cx43 C-terminal domain bound to tubulin | Descriptor: | Gap junction alpha-1 protein | Authors: | Saidi Brikci-Nigassa, A, Clement, M, Ha-Duong, T, Benmansour, K, Adjadj, E, Ziani, L, Pastre, D, Curmi, P.A. | Deposit date: | 2011-10-26 | Release date: | 2012-06-20 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Phosphorylation controls the interaction of the connexin43 C-terminal domain with tubulin and microtubules. Biochemistry, 51, 2012
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7QEO
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![BU of 7qeo by Molmil](/molmil-images/mine/7qeo) | human Connexin 26 at 55mm Hg PCO2, pH7.4: two masked subunits, class C | Descriptor: | DODECYL-BETA-D-MALTOSIDE, Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE | Authors: | Brotherton, D.H, Cameron, A.D, Savva, C.G, Ragan, T.J. | Deposit date: | 2021-12-03 | Release date: | 2022-06-22 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Conformational changes and CO 2 -induced channel gating in connexin26. Structure, 30, 2022
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7QEV
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![BU of 7qev by Molmil](/molmil-images/mine/7qev) | human Connexin 26 at 55mm Hg PCO2, pH7.4:two masked subunits, class D | Descriptor: | DODECYL-BETA-D-MALTOSIDE, Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE | Authors: | Brotherton, D.H, Cameron, A.D, Savva, C.G, Ragan, T.J. | Deposit date: | 2021-12-03 | Release date: | 2022-06-15 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Conformational changes and CO 2 -induced channel gating in connexin26. Structure, 30, 2022
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7QES
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![BU of 7qes by Molmil](/molmil-images/mine/7qes) | human Connexin 26 at 55mm Hg PCO2, pH7.4: two masked subunits, class A | Descriptor: | DODECYL-BETA-D-MALTOSIDE, Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE | Authors: | Brotherton, D.H, Cameron, A.D, Savva, C.G, Ragan, T.J. | Deposit date: | 2021-12-03 | Release date: | 2022-06-15 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Conformational changes and CO 2 -induced channel gating in connexin26. Structure, 30, 2022
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1LNH
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![BU of 1lnh by Molmil](/molmil-images/mine/1lnh) | |
7QEU
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![BU of 7qeu by Molmil](/molmil-images/mine/7qeu) | human Connexin 26 at 55mmHg PCO2, pH7.4: two masked subunits, class B | Descriptor: | DODECYL-BETA-D-MALTOSIDE, Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE | Authors: | Brotherton, D.H, Cameron, A.D, Savva, C.G, Ragan, T.J. | Deposit date: | 2021-12-03 | Release date: | 2022-06-15 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Conformational changes and CO 2 -induced channel gating in connexin26. Structure, 30, 2022
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