PDB: 55698 resultsInfo pagesStatus searchChemie searchBIRD

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8TL7	CryoEM Structure of a Computationally Designed T3 Tetrahedral Nanocage Descriptor: Computationally designed protein Authors: Weidle, C, Borst, A.J. Deposit date: 2023-07-26 Release date: 2024-03-13 Last modified: 2024-04-10 Method: ELECTRON MICROSCOPY (4.05 Å) Cite: Blueprinting extendable nanomaterials with standardized protein blocks. Nature, 627, 2024
8TYN	Cryo-EM of the GDP-bound human dynamin polymer assembled on the membrane in the super constricted state (tetramer model) Descriptor: Dynamin-1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION Authors: Jimah, J.R, Canagarajah, B.J, Hinshaw, J.E. Deposit date: 2023-08-25 Release date: 2024-06-12 Method: ELECTRON MICROSCOPY (3.26 Å) Cite: Cryo-EM structures of membrane-bound dynamin in a post-hydrolysis state primed for membrane fission. Dev.Cell, 2024
8WKL	Rauvolfia serpentina strictosidine synthase (RsSTR) in complex with a non-reactive tryptamine substitute crystallized in P1211 space group Descriptor: 2-(2-methyl-1H-indol-3-yl)ethanamine, DI(HYDROXYETHYL)ETHER, Strictosidine synthase Authors: Nitin, K, Rajakumara, E. Deposit date: 2023-09-28 Release date: 2024-02-28 Method: X-RAY DIFFRACTION (2.67 Å) Cite: Proxy-approach in understanding the bisubstrate activity of strictosidine synthases. Int.J.Biol.Macromol., 262, 2024
8TJY	Structure of Gabija AB complex Descriptor: Endonuclease GajA, Gabija protein GajB Authors: Shen, Z.F, Yang, X.Y, Fu, T.M. Deposit date: 2023-07-24 Release date: 2024-04-24 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (2.79 Å) Cite: Molecular basis of Gabija anti-phage supramolecular assemblies. Nat.Struct.Mol.Biol., 2024
1WDL	fatty acid beta-oxidation multienzyme complex from Pseudomonas fragi, form II (native4) Descriptor: 3,6,9,12,15-PENTAOXATRICOSAN-1-OL, 3-ketoacyl-CoA thiolase, ACETYL COENZYME *A, ... Authors: Ishikawa, M, Tsuchiya, D, Oyama, T, Tsunaka, Y, Morikawa, K. Deposit date: 2004-05-17 Release date: 2004-07-27 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Structural basis for channelling mechanism of a fatty acid beta-oxidation multienzyme complex Embo J., 23, 2004
8U4T	Structure of tetrameric CXCR4 in complex with REGN7663 Fab Descriptor: (2R)-1-(hexadecanoyloxy)-3-(phosphonooxy)propan-2-yl (9Z)-octadec-9-enoate, C-X-C chemokine receptor type 4, CHOLESTEROL, ... Authors: Saotome, K, McGoldrick, L.L, Franklin, M.C. Deposit date: 2023-09-11 Release date: 2024-03-13 Method: ELECTRON MICROSCOPY (3.38 Å) Cite: Structural insights into CXCR4 modulation and oligomerization Biorxiv, 2024
9AXC	Activated CRAF/MEK heterotetramer from focused refinement of CRAF/MEK/14-3-3 complex Descriptor: Dual specificity mitogen-activated protein kinase kinase 1, GST26/CRAF chimera, N-[3-fluoro-4-({7-[(3-fluoropyridin-2-yl)oxy]-4-methyl-2-oxo-2H-1-benzopyran-3-yl}methyl)pyridin-2-yl]-N'-methylsulfuric diamide Authors: Quade, B, Cohen, S.E, Huang, X. Deposit date: 2024-03-06 Release date: 2024-04-17 Last modified: 2024-07-10 Method: ELECTRON MICROSCOPY (4.16 Å) Cite: The Pan-RAF-MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS-MAPK Pathway with Activity across Diverse RAS- and RAF-Driven Cancers. Cancer Discov, 14, 2024
8UMC	Deinococcus aerius TR0125 C-glucosyl deglycosidase (CGD), cryo-EM Descriptor: DUF6379 domain-containing protein, MANGANESE (II) ION, Xylose isomerase-like TIM barrel domain-containing protein Authors: Furlanetto, V, Kalyani, D.C, Kostelac, A, Haltrich, D, Hallberg, B.M, Divne, C. Deposit date: 2023-10-17 Release date: 2024-05-29 Method: ELECTRON MICROSCOPY (2.5 Å) Cite: Structural and Functional Characterization of a Gene Cluster Responsible for Deglycosylation of C-glucosyl Flavonoids and Xanthonoids by Deinococcus aerius. J.Mol.Biol., 436, 2024
8XC6	Crystal structure of large stokes shift red fluorescent protein tKeima Descriptor: fluorescent protein Authors: Nam, K.H. Deposit date: 2023-12-08 Release date: 2024-04-17 Last modified: 2024-07-10 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural Analysis of the Large Stokes Shift Red Fluorescent Protein tKeima. Molecules, 29, 2024
8XFQ	Structure of the alginate epimerase/lyase complexed with penta-mannuronic acid Descriptor: CALCIUM ION, DI(HYDROXYETHYL)ETHER, TRIETHYLENE GLYCOL, ... Authors: Fujiwara, T. Deposit date: 2023-12-14 Release date: 2024-05-15 Last modified: 2024-06-26 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Structural basis for the minimal bifunctional alginate epimerase AlgE3 from Azotobacter chroococcum. Febs Lett., 598, 2024
8WTQ	HUMAN SQUALENE SYNTHASE IN COMPLEX WITH {1-[2-Chloro-5-(2,2-dimethyl-propyl)-13-(2-methoxy-phenyl)-6-oxo-6,7,10,11-tetrahydro-5H,9H,13H-12-oxa-5,8-diaza-benzocycloundecene-8-carbonyl]-piperidin-4-yl}-acetic acid Descriptor: 2-[1-[[(10~{S})-13-chloranyl-2-(2,2-dimethylpropyl)-10-(2-methoxyphenyl)-3-oxidanylidene-9-oxa-2,5-diazabicyclo[9.4.0]pentadeca-1(15),11,13-trien-5-yl]carbonyl]piperidin-4-yl]ethanoic acid, PHOSPHATE ION, Squalene synthase Authors: Suzuki, M, Haginoya, N, Suzuki, M, Ishigai, Y, Terayama, K, Kanda, A, Sugita, K. Deposit date: 2023-10-19 Release date: 2024-05-22 Method: X-RAY DIFFRACTION (2 Å) Cite: Discovery of Novel 11-Membered Templates as Squalene Synthase Inhibitors. J.Med.Chem., 67, 2024
8VC2	CryoEM structure of insect gustatory receptor BmGr9 in the presence of fructose Descriptor: (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, Gustatory receptor Authors: Frank, H.M, Walsh Jr, R.M, Garrity, P.A, Gaudet, R. Deposit date: 2023-12-13 Release date: 2024-01-10 Last modified: 2024-01-24 Method: ELECTRON MICROSCOPY (3.98 Å) Cite: Structure of an insect gustatory receptor. Biorxiv, 2023
9B5E	Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - Ub(T) class 10 map and model from consensus Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, Large ribosomal subunit protein eL40B, ... Authors: Kochanczyk, T, Lima, C.D. Deposit date: 2024-03-22 Release date: 2024-06-05 Method: ELECTRON MICROSCOPY (2.81 Å) Cite: Structural basis for transthiolation intermediates in the ubiquitin pathway To be published
8VC1	CryoEM structure of insect gustatory receptor BmGr9 Descriptor: (3beta,14beta,17beta,25R)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, (7S)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, ... Authors: Frank, H.M, Walsh Jr, R.M, Garrity, P.A, Gaudet, R. Deposit date: 2023-12-13 Release date: 2024-01-10 Last modified: 2024-01-24 Method: ELECTRON MICROSCOPY (2.85 Å) Cite: Structure of an insect gustatory receptor. Biorxiv, 2023
9B5G	Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - cluster 2 map and model (Ub(A)/ATP/Mg) Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, Large ribosomal subunit protein eL40B, ... Authors: Kochanczyk, T, Lima, C.D. Deposit date: 2024-03-22 Release date: 2024-06-05 Method: ELECTRON MICROSCOPY (2.67 Å) Cite: Structural basis for transthiolation intermediates in the ubiquitin pathway To be published
9B5L	Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - Ub(T) class 10 map and model from cluster 5 (Ub(A)-AMP) Descriptor: 4-aminobutanenitrile, ADENOSINE MONOPHOSPHATE, Polyubiquitin, ... Authors: Kochanczyk, T, Lima, C.D. Deposit date: 2024-03-22 Release date: 2024-06-05 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Structural basis for transthiolation intermediates in the ubiquitin pathway To be published
9FBY	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 with (5-(4-chloro-1-((tetrahydro-2H-pyran-4-yl)methyl)-1H-imidazol-2-yl)-1,3-dimethylpyridin-2(1H)-one Descriptor: 1,2-ETHANEDIOL, 5-[4-chloranyl-1-(oxan-4-ylmethyl)imidazol-2-yl]-1,3-dimethyl-pyridin-2-one, Bromodomain-containing protein 4 Authors: Chung, C. Deposit date: 2024-05-14 Release date: 2024-06-26 Last modified: 2024-07-10 Method: X-RAY DIFFRACTION (1.853 Å) Cite: Structure- and Property-Based Optimization of Efficient Pan-Bromodomain and Extra Terminal Inhibitors to Identify Oral and Intravenous Candidate I-BET787. J.Med.Chem., 67, 2024
9B5D	Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - Ub(T) class 1 map and model from consensus Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, Large ribosomal subunit protein eL40B, ... Authors: Kochanczyk, T, Lima, C.D. Deposit date: 2024-03-22 Release date: 2024-06-05 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Structural basis for transthiolation intermediates in the ubiquitin pathway To be published
9B5H	Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - cluster 3 map and model (Ub(A)-AMP/PPi/Mg) Descriptor: 4-aminobutanenitrile, ADENOSINE MONOPHOSPHATE, Large ribosomal subunit protein eL40B, ... Authors: Kochanczyk, T, Lima, C.D. Deposit date: 2024-03-22 Release date: 2024-06-05 Method: ELECTRON MICROSCOPY (2.69 Å) Cite: Structural basis for transthiolation intermediates in the ubiquitin pathway To be published
9B5I	Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - cluster 4 map and model (Ub(A)-AMP/PPi/Mg) Descriptor: 4-aminobutanenitrile, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, ... Authors: Kochanczyk, T, Lima, C.D. Deposit date: 2024-03-22 Release date: 2024-06-05 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: Structural basis for transthiolation intermediates in the ubiquitin pathway To be published
9B5F	Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - cluster 1 map and model (Ub(A)/ATP/Mg) Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... Authors: Kochanczyk, T, Lima, C.D. Deposit date: 2024-03-22 Release date: 2024-06-05 Method: ELECTRON MICROSCOPY (2.78 Å) Cite: Structural basis for transthiolation intermediates in the ubiquitin pathway To be published
9BCB	Crystal structure of human cellular retinol binding protein 3 in complex with C11 TopFluor MG Descriptor: 1-[11-(dipyrrometheneboron difluoride)undecanoyl]-rac-glycerol, GLYCEROL, Retinol-binding protein 5 Authors: Golczak, M. Deposit date: 2024-04-08 Release date: 2024-04-17 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Interactom of cellular retinol binding protein 3. To Be Published
8XYB	hPhK gamma-delta subcomplex in inactive state Descriptor: Calmodulin-1, FARNESYL, Phosphorylase b kinase gamma catalytic chain, ... Authors: Yang, X.K, Xiao, J.Y. Deposit date: 2024-01-19 Release date: 2024-04-03 Last modified: 2024-04-10 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Architecture and activation of human muscle phosphorylase kinase. Nat Commun, 15, 2024
9B5K	Ubiquitin E1-Ub-E2 tetrahedral transthiolation intermediate mimic (doubly Ub-loaded) - Ub(T) class 1 map and model from cluster 1 (Ub(A)/ATP/Mg) Descriptor: 4-aminobutanenitrile, ADENOSINE-5'-TRIPHOSPHATE, Large ribosomal subunit protein eL40B, ... Authors: Kochanczyk, T, Lima, C.D. Deposit date: 2024-03-22 Release date: 2024-06-05 Method: ELECTRON MICROSCOPY (3.16 Å) Cite: Structural basis for transthiolation intermediates in the ubiquitin pathway To be published
8TK1	Structure of Gabija AB complex 1 Descriptor: Endonuclease GajA, Gabija protein GajB Authors: Shen, Z.F, Yang, X.Y, Fu, T.M. Deposit date: 2023-07-25 Release date: 2024-04-24 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (2.98 Å) Cite: Molecular basis of Gabija anti-phage supramolecular assemblies. Nat.Struct.Mol.Biol., 2024

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