2LTU
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3KCC
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![BU of 3kcc by Molmil](/molmil-images/mine/3kcc) | Crystal structure of D138L mutant of Catabolite Gene Activator Protein | Descriptor: | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator | Authors: | Tao, W.B, Gao, Z.Q, Zhou, J.H, Dong, Y.H, Yu, S.N. | Deposit date: | 2009-10-21 | Release date: | 2009-11-17 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | The 1.6A resolution structure of activated D138L mutant of catabolite gene activator protein with two cAMP bound in each monomer Int.J.Biol.Macromol., 48, 2011
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1ZUV
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![BU of 1zuv by Molmil](/molmil-images/mine/1zuv) | 24 NMR structures of AcAMP2-Like Peptide with Phenylalanine 18 mutated to Tryptophan | Descriptor: | AMARANTHUS CAUDATUS ANTIMICROBIAL PEPTIDE 2 | Authors: | Chavez, M.I, Andreu, C, Vidal, P, Freire, F, Aboitiz, N, Groves, P, Asensio, J.L, Asensio, G, Muraki, M, Canada, F.J, Jimenez-Barbero, J. | Deposit date: | 2005-06-01 | Release date: | 2005-12-06 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | On the Importance of Carbohydrate-Aromatic Interactions for the Molecular Recognition of Oligosaccharides by Proteins: NMR Studies of the Structure and Binding Affinity of AcAMP2-like Peptides with Non-Natural Naphthyl and Fluoroaromatic Residues Chemistry, 11, 2005
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8B70
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![BU of 8b70 by Molmil](/molmil-images/mine/8b70) | KimA from B. subtilis with nucleotide second-messenger c-di-AMP bound | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, DODECYL-BETA-D-MALTOSIDE, POTASSIUM ION, ... | Authors: | Vonck, J, Wieferig, J.P. | Deposit date: | 2022-09-28 | Release date: | 2023-01-18 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cyclic di-AMP traps proton-coupled K + transporters of the KUP family in an inward-occluded conformation. Nat Commun, 14, 2023
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8B71
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![BU of 8b71 by Molmil](/molmil-images/mine/8b71) | Upright KimA dimer with bound c-di-AMP from B. subtilis | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, Potassium transporter KimA | Authors: | Vonck, J, Wieferig, J.P. | Deposit date: | 2022-09-28 | Release date: | 2023-01-18 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Cyclic di-AMP traps proton-coupled K + transporters of the KUP family in an inward-occluded conformation. Nat Commun, 14, 2023
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3MZH
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2ONJ
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3KD6
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3LFR
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7UTT
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2XXB
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8OFG
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1Z6P
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![BU of 1z6p by Molmil](/molmil-images/mine/1z6p) | Glycogen phosphorylase AMP site inhibitor complex | Descriptor: | 4-{2-[(3-NITROBENZOYL)AMINO]PHENOXY}PHTHALIC ACID, Glycogen phosphorylase, muscle form | Authors: | Kristiansen, M, Andersen, B, Iversen, L.F, Westergaard, N. | Deposit date: | 2005-03-23 | Release date: | 2005-04-12 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Identification, synthesis and chracterization of new glycogen phosphorylase inhibitors binding to the allosteric AMP site J.Med.Chem., 47, 2004
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1Z6Q
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![BU of 1z6q by Molmil](/molmil-images/mine/1z6q) | Glycogen phosphorylase with inhibitor in the AMP site | Descriptor: | 4-{2,4-BIS[(3-NITROBENZOYL)AMINO]PHENOXY}PHTHALIC ACID, Glycogen phosphorylase, muscle form | Authors: | Kristiansen, M, Andersen, B, Iversen, L.F, Westergaard, N. | Deposit date: | 2005-03-23 | Release date: | 2005-04-12 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Identification, synthesis and chracterization of new glycogen phosphorylase inhibitors binding to the allosteric AMP site J.Med.Chem., 47, 2004
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3LW7
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![BU of 3lw7 by Molmil](/molmil-images/mine/3lw7) | The Crystal Structure of an Adenylate kinase-related protein bound to AMP from sulfolobus solfataricus to 2.3A | Descriptor: | ADENOSINE MONOPHOSPHATE, Adenylate kinase related protein (AdkA-like) | Authors: | Stein, A.J, Sather, A, Hendricks, R, Abdullah, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2010-02-23 | Release date: | 2010-03-09 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The Crystal Structure of an Adenylate kinase-related protein bound to AMP from sulfolobus solfataricus to 2.3A To be Published
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3S1Y
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![BU of 3s1y by Molmil](/molmil-images/mine/3s1y) | AMP-C BETA-LACTAMASE (PSEUDOMONAS AERUGINOSA) in complex with a beta-lactamase inhibitor | Descriptor: | Beta-lactamase, CHLORIDE ION, ISOPROPYL ALCOHOL, ... | Authors: | Scapin, G, Lu, J, Fitzgerald, P.M.D, Sharma, N. | Deposit date: | 2011-05-16 | Release date: | 2011-06-29 | Last modified: | 2013-06-26 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Side chain SAR of bicyclic Beta-lactamase inhibitors (BLIs). 2. N-Alkylated and open chain analogs of MK-8712 Bioorg.Med.Chem.Lett., 21, 2011
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3SQW
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3SQX
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1LEV
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![BU of 1lev by Molmil](/molmil-images/mine/1lev) | PORCINE KIDNEY FRUCTOSE-1,6-BISPHOSPHATASE COMPLEXED WITH AN AMP-SITE INHIBITOR | Descriptor: | 3-(2-CARBOXY-ETHYL)-4,6-DICHLORO-1H-INDOLE-2-CARBOXYLIC ACID, 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase, ... | Authors: | Wright, S.W, Carlo, A.A, Danley, D.E, Hageman, D.L, Karam, G.A, Mansour, M.N, McClure, L.D, Pandit, J, Schulte, G.K, Treadway, J.L, Wang, I.-K, Bauer, P.H. | Deposit date: | 2002-04-10 | Release date: | 2002-10-16 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | 3-(2-carboxyethyl)-4,6-dichloro-1H-indole-2-carboxylic acid: an allosteric inhibitor of fructose-1,6-bisphosphatase at the AMP site. Bioorg.Med.Chem.Lett., 13, 2003
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7C9Q
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![BU of 7c9q by Molmil](/molmil-images/mine/7c9q) | Crystal structure of Human liver fructose-1,6-bisphoaphatase complex with Mg2+ and AMP | Descriptor: | ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase 1, MAGNESIUM ION | Authors: | Huang, Y, Li, R, Wan, J. | Deposit date: | 2020-06-07 | Release date: | 2021-06-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.878 Å) | Cite: | Crystal structure of Human liver fructose-1,6-bisphoaphatase complex with Mg2+ and AMP To Be Published
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5M0B
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6ZMD
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![BU of 6zmd by Molmil](/molmil-images/mine/6zmd) | Crystal structure of HYPE covalently tethered to BiP bound to AMP-PNP | Descriptor: | Endoplasmic reticulum chaperone BiP, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Fauser, J, Gulen, B, Pett, C, Hedberg, C, Itzen, A, Pogenberg, V. | Deposit date: | 2020-07-02 | Release date: | 2021-04-14 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | Specificity of AMPylation of the human chaperone BiP is mediated by TPR motifs of FICD. Nat Commun, 12, 2021
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5M6Y
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![BU of 5m6y by Molmil](/molmil-images/mine/5m6y) | Cocrystal structure of cAMP-dependent Protein Kinase (PKA) in complex with a methylisoquinoline Fasudil-derivative | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 5-(1,4-diazepan-1-ylsulfonyl)-4-methyl-isoquinoline, cAMP-dependent protein kinase catalytic subunit alpha, ... | Authors: | Wienen-Schmidt, B, Heine, A, Klebe, G. | Deposit date: | 2016-10-26 | Release date: | 2018-06-06 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.367 Å) | Cite: | Cocrystal structure of cAMP-dependent Protein Kinase (PKA) in complex with differently methylated Fasudil-derived ligands To be Published
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5M75
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5M0U
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