7NDU
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![BU of 7ndu by Molmil](/molmil-images/mine/7ndu) | Gag:02 TCR in complex with HLA-E featuring a non-natural amino acid | Descriptor: | Beta-2-microglobulin, Gag6V(276-284 H4C), HLA class I histocompatibility antigen, ... | Authors: | Pengelly, R.J, Robinson, R.A. | Deposit date: | 2021-02-02 | Release date: | 2022-01-26 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition. Eur.J.Immunol., 52, 2022
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7NDQ
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![BU of 7ndq by Molmil](/molmil-images/mine/7ndq) | Gag:02 TCR in complex with HLA-E. | Descriptor: | Beta-2-microglobulin, Gag6V, HLA class I histocompatibility antigen, ... | Authors: | Pengelly, R.J, Robinson, R.A. | Deposit date: | 2021-02-02 | Release date: | 2022-01-26 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.551 Å) | Cite: | Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition. Eur.J.Immunol., 52, 2022
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7N9J
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![BU of 7n9j by Molmil](/molmil-images/mine/7n9j) | Crystal structure of H2DB in complex with HSF2 melanoma neoantigen | Descriptor: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... | Authors: | Patskovsky, Y, Finnigan, J, Patskovska, L, Newman, J, Bhardwaj, N, Krogsgaard, M. | Deposit date: | 2021-06-18 | Release date: | 2022-06-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Structure of the complex between H2DB and melanoma HSF2 neoantigen YGFRNVVHI To be Published
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7NA5
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![BU of 7na5 by Molmil](/molmil-images/mine/7na5) | Structure of the H2DB-TCR ternary complex with HSF2 melanoma neoantigen | Descriptor: | 47BE7 TCR alpha chain, 47BE7 TCR beta chain, Beta-2-microglobulin, ... | Authors: | Patskovsky, Y, Finnigan, J, Patskovska, L, Newman, J, Bhardwaj, N, Krogsgaard, M. | Deposit date: | 2021-06-19 | Release date: | 2022-06-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the TCR-H2DB ternary complex with melanoma HSF2 neoantigen YGFRNVVHI To be Published
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7NMD
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![BU of 7nmd by Molmil](/molmil-images/mine/7nmd) | |
7NME
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![BU of 7nme by Molmil](/molmil-images/mine/7nme) | Human MHC Class I, A24 Allele presenting QLPRLFPLL, Complex with 4C6 TCR | Descriptor: | 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4C6 Human T-cell Receptor, ... | Authors: | Rizkallah, P.J, Sewell, A.K, Cole, D.K, Wall, A. | Deposit date: | 2021-02-23 | Release date: | 2022-09-07 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Human MHC Class I, A24 Allele presenting QLPRLFPLL, Complex with 4C6 TCR To Be Published
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7NMG
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![BU of 7nmg by Molmil](/molmil-images/mine/7nmg) | Human MHC Class I, A24 Allele presenting LWM, Complex with 4C6 TCR | Descriptor: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Diabetes epitope LWMRLLPLL, ... | Authors: | Rizkallah, P.J, Sewell, A.K, Cole, D.K, Wall, A. | Deposit date: | 2021-02-23 | Release date: | 2022-09-07 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Human MHC Class I, A24 Allele presenting LWM, Complex with 4C6 TCR To Be Published
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7NMF
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![BU of 7nmf by Molmil](/molmil-images/mine/7nmf) | Human MHC Class I, A24 Allele presenting QLPRLFPLL, Complex with 4C6 TCR, monoclinic form | Descriptor: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLN-LEU-PRO-ARG-LEU-PHE-PRO-LEU-LEU, ... | Authors: | Rizkallah, P.J, Sewell, A.K, Cole, D.K, Wall, A. | Deposit date: | 2021-02-23 | Release date: | 2022-09-07 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.98 Å) | Cite: | Human MHC Class I, A24 Allele presenting QLPRLFPLL, Complex with 4C6 TCR, monoclinic form To Be Published
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7N4K
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![BU of 7n4k by Molmil](/molmil-images/mine/7n4k) | 6218 TCR in complex with H2-Db PA 224 | Descriptor: | Beta-2-microglobulin, Fusion protein of T cell receptor alpha variable 21-DV12 and T-cell receptor, sp3.4 alpha chain, ... | Authors: | Szeto, C, Gras, S. | Deposit date: | 2021-06-04 | Release date: | 2022-07-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus. Nat Commun, 13, 2022
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7N5C
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![BU of 7n5c by Molmil](/molmil-images/mine/7n5c) | 6218 TCR in complex with H2Db PA with an engineered TCR-pMHC disulfide bond | Descriptor: | Beta-2-microglobulin, Fusion protein of T cell receptor alpha variable 21-DV12 with T-cell receptor, sp3.4 alpha chain, ... | Authors: | Szeto, C, Gras, S. | Deposit date: | 2021-06-05 | Release date: | 2022-07-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus. Nat Commun, 13, 2022
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7N5P
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![BU of 7n5p by Molmil](/molmil-images/mine/7n5p) | 6218 TCR in complex with H2-Db PA224-233 with a cysteine mutant | Descriptor: | Beta-2-microglobulin, Fusion protein of T cell receptor alpha variable 21-DV12 and T-cell receptor, sp3.4 alpha chain, ... | Authors: | Szeto, C, Gras, S. | Deposit date: | 2021-06-06 | Release date: | 2022-07-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus. Nat Commun, 13, 2022
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7N5Q
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![BU of 7n5q by Molmil](/molmil-images/mine/7n5q) | |
7N2O
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![BU of 7n2o by Molmil](/molmil-images/mine/7n2o) | AS4.2-YEIH-HLA*B27 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, GLYCEROL, ... | Authors: | Yang, X, Jude, K.M, Garcia, K.C. | Deposit date: | 2021-05-29 | Release date: | 2022-12-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature, 612, 2022
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7N2Q
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![BU of 7n2q by Molmil](/molmil-images/mine/7n2q) | AS4.3-YEIH-HLA*B27 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, AS4.3 T cell receptor alpha chain, AS4.3 T cell receptor beta chain, ... | Authors: | Yang, X, Jude, K.M, Garcia, K.C. | Deposit date: | 2021-05-29 | Release date: | 2022-12-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature, 612, 2022
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7N2S
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![BU of 7n2s by Molmil](/molmil-images/mine/7n2s) | AS3.1-PRPF3-HLA*B27 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, GLYCEROL, ... | Authors: | Yang, X, Jude, K.M, Garcia, K.C. | Deposit date: | 2021-05-29 | Release date: | 2022-12-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature, 612, 2022
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7N2R
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![BU of 7n2r by Molmil](/molmil-images/mine/7n2r) | AS4.3-PRPF3-HLA*B27 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, AS4.3 T cell receptor alpha chain, ... | Authors: | Yang, X, Jude, K.M, Garcia, K.C. | Deposit date: | 2021-05-29 | Release date: | 2022-12-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature, 612, 2022
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7N2N
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![BU of 7n2n by Molmil](/molmil-images/mine/7n2n) | TCR-antigen complex AS4.2-PRPF3-HLA*B27 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, GLYCEROL, ... | Authors: | Yang, X, Jude, K.M, Garcia, K.C. | Deposit date: | 2021-05-29 | Release date: | 2022-12-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature, 612, 2022
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7N2P
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![BU of 7n2p by Molmil](/molmil-images/mine/7n2p) | AS4.3-RNASEH2b-HLA*B27 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, AS4.3 T cell receptor alpha chain, AS4.3 T cell receptor beta chain, ... | Authors: | Yang, X, Jude, K.M, Garcia, K.C. | Deposit date: | 2021-05-29 | Release date: | 2022-12-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides. Nature, 612, 2022
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7O00
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![BU of 7o00 by Molmil](/molmil-images/mine/7o00) | Crystal structure of HLA-DR4 in complex with a HSP70 peptide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chaperone protein DnaK, ... | Authors: | Ge, C, Holmdahl, R. | Deposit date: | 2021-03-25 | Release date: | 2022-05-11 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Key interactions in the trimolecular complex consisting of the rheumatoid arthritis-associated DRB1*04:01 molecule, the major glycosylated collagen II peptide and the T-cell receptor. Ann Rheum Dis, 81, 2022
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7NZE
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![BU of 7nze by Molmil](/molmil-images/mine/7nze) | Crystal structure of HLA-DR4 in complex with a human collagen type II peptide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Collagen alpha-1(II) chain, GLYCEROL, ... | Authors: | Ge, C, Dobritzsch, D, Holmdahl, R. | Deposit date: | 2021-03-24 | Release date: | 2022-06-08 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Key interactions in the trimolecular complex consisting of the rheumatoid arthritis-associated DRB1*04:01 molecule, the major glycosylated collagen II peptide and the T-cell receptor. Ann Rheum Dis, 81, 2022
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7P3D
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![BU of 7p3d by Molmil](/molmil-images/mine/7p3d) | MHC I A02 Allele presenting YLQPRTFLL | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Beta-2-microglobulin, ... | Authors: | Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A. | Deposit date: | 2021-07-07 | Release date: | 2021-07-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Emergence of immune escape at dominant SARS-CoV-2 killer T cell epitope. Cell, 185, 2022
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7P3E
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![BU of 7p3e by Molmil](/molmil-images/mine/7p3e) | MHC I A02 Allele presenting YLQLRTFLL | Descriptor: | Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, IODIDE ION, ... | Authors: | Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A. | Deposit date: | 2021-07-07 | Release date: | 2021-07-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Emergence of immune escape at dominant SARS-CoV-2 killer T cell epitope. Cell, 185, 2022
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7P0T
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![BU of 7p0t by Molmil](/molmil-images/mine/7p0t) | |
7P0A
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![BU of 7p0a by Molmil](/molmil-images/mine/7p0a) | |
7PBE
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![BU of 7pbe by Molmil](/molmil-images/mine/7pbe) | Emergence of immune escape at dominant SARS-CoV-2 killer T-cell epitope | Descriptor: | Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, Human T-cell Receptor YLQ36, ... | Authors: | Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A. | Deposit date: | 2021-08-02 | Release date: | 2022-04-27 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Emergence of immune escape at dominant SARS-CoV-2 killer T cell epitope. Cell, 185, 2022
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