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9B8N
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BU of 9b8n by Molmil
Crystal structure of ornithine decarboxylase in complex with a novel inhibitor (10-S)
Descriptor: O-{[(3S)-pyrrolidin-3-yl]methyl}hydroxylamine, Ornithine decarboxylase, PYRIDOXAL-5'-PHOSPHATE
Authors:Schultz, C.R, Aleiwi, B, Zhou, X.E, Suino-Powell, K, Melcher, K, Brunzelle, J.S, Almeida, N.M.S, Wilson, A.K, Ellsworth, E, Bachmann, A.S.
Deposit date:2024-03-31
Release date:2025-03-12
Last modified:2025-03-26
Method:X-RAY DIFFRACTION (2 Å)
Cite:Design, Synthesis, and Biological Activity of Novel Ornithine Decarboxylase (ODC) Inhibitors.
J.Med.Chem., 68, 2025
9B8M
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BU of 9b8m by Molmil
Crystal structure of ornithine decarboxylase in complex with a novel inhibitor
Descriptor: O-{[(3R)-pyrrolidin-3-yl]methyl}hydroxylamine, Ornithine decarboxylase, PYRIDOXAL-5'-PHOSPHATE
Authors:Schultz, C.R, Aleiwi, B, Zhou, X.E, Suino-Powell, K, Melcher, K, Brunzelle, J.S, Almeida, N.M.S, Wilson, A.K, Ellsworth, E, Bachmann, A.S.
Deposit date:2024-03-31
Release date:2025-03-12
Last modified:2025-03-26
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Design, Synthesis, and Biological Activity of Novel Ornithine Decarboxylase (ODC) Inhibitors.
J.Med.Chem., 68, 2025
9BUS
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BU of 9bus by Molmil
Single particle CryoEM structure of the Pf80S ribosome in the unloaded state (nrt with E-site tRNA)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Anton, L, Haile, M, Ho, C.M.
Deposit date:2024-05-17
Release date:2025-05-28
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Inhibiting elongation factor binding to the malarial 80S ribosome triggers ribosome biogenesis
To Be Published
9BUQ
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BU of 9buq by Molmil
Single particle cryoEM structure of the Pf80S ribosome in the POST state (nrt with P- and E-site tRNA)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Anton, L, Haile, M, Ho, C.M.
Deposit date:2024-05-17
Release date:2025-05-28
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Inhibition elongation factor binding to the malarial 80S ribosome triggers ribosome biogenesis
To Be Published
9BUT
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BU of 9but by Molmil
Single particle CryoEM structure of the Pf80S ribosome in the rotated-2 PRE state (rt state with P and E-site tRNA)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Anton, L, Haile, M, Ho, C.M.
Deposit date:2024-05-17
Release date:2025-05-28
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Inhibiting elongation factor binding to the malarial 80S ribosome triggers ribosome biogenesis
To Be Published
9BUU
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BU of 9buu by Molmil
Single particle CryoEM structure of the Pf80S ribosome in rotated state with E-site tRNA
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Anton, L, Haile, M, Ho, C.M.
Deposit date:2024-05-17
Release date:2025-05-28
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Inhibiting elongation factor binding to the malarial 80S ribosome triggers ribosome biogenesis
To Be Published
9BUP
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BU of 9bup by Molmil
Single particle CryoEM structure of the Pf80S ribosome in non-rotated PRE state (nrt A-P-E)
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Anton, L, Haile, M, Ho, C.M.
Deposit date:2024-05-17
Release date:2025-05-28
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Inhibiting elongation factor binding to the malarial 80S ribosome triggers ribosome biogenesis
To be published
8UJK
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BU of 8ujk by Molmil
In situ HHT and CHX treated A-P-Z state 80S ribosome
Descriptor: (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 18S rRNA, 28S rRNA, ...
Authors:Wei, Z, Yong, X.
Deposit date:2023-10-11
Release date:2025-04-16
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:In situ HHT and CHX treated human A-P-Z state 80S ribosome
To Be Published
8UJ9
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BU of 8uj9 by Molmil
In situ human P state 80S ribosome
Descriptor: 18S rRNA [Homo sapiens], 28S rRNA [Homo sapiens], 40S ribosomal protein S10, ...
Authors:Wei, Z, Yong, X.
Deposit date:2023-10-11
Release date:2025-04-16
Method:ELECTRON MICROSCOPY (3.64 Å)
Cite:In situ human P state 80S ribosome
To Be Published
8UJJ
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BU of 8ujj by Molmil
In situ HHT and CHX treated A-P state 80S ribosome
Descriptor: (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 18S rRNA, 28S rRNA, ...
Authors:Wei, Z, Yong, X.
Deposit date:2023-10-11
Release date:2025-04-16
Method:ELECTRON MICROSCOPY (3.56 Å)
Cite:In situ HHT and CHX treated human A-P state 80S ribosome
To Be Published
8UIY
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BU of 8uiy by Molmil
In situ human P-Z state 80S ribosome
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Wei, Z, Yong, X.
Deposit date:2023-10-10
Release date:2025-04-09
Method:ELECTRON MICROSCOPY (3.44 Å)
Cite:In situ human P-Z state 80S ribosome
To Be Published
8UIK
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BU of 8uik by Molmil
In situ HHT and CHX treated human 80S ribosome with EBP1 (consensus map)
Descriptor: (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 18S rRNA, 28S rRNA, ...
Authors:Wei, Z, Yong, X.
Deposit date:2023-10-10
Release date:2025-04-30
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:In situ HHT and CHX treated human 80S ribosome with EBP1 (consensus map)
To Be Published
8UJB
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BU of 8ujb by Molmil
In situ human 80S ribosome with EBP1 (consensus map)
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Wei, Z, Yong, X.
Deposit date:2023-10-11
Release date:2025-04-30
Method:ELECTRON MICROSCOPY (2.67 Å)
Cite:In situ human 80S ribosome with EBP1 (Consensus map)
To Be Published
8UIZ
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BU of 8uiz by Molmil
In situ human P-E state 80S ribosome
Descriptor: 18S rRNA [Homo sapiens], 28S rRNA, 40S ribosomal protein S10, ...
Authors:Wei, Z, Yong, X.
Deposit date:2023-10-10
Release date:2025-04-09
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:In situ human P-E state 80S ribosome
To Be Published
3HPR
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BU of 3hpr by Molmil
Crystal structure of V148G adenylate kinase from E. coli, in complex with Ap5A
Descriptor: Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE
Authors:Hilser, V.J, Travis, T.P, Bolen, D.W.
Deposit date:2009-06-04
Release date:2009-11-03
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Rational modulation of conformational fluctuations in adenylate kinase reveals a local unfolding mechanism for allostery and functional adaptation in proteins.
Proc.Natl.Acad.Sci.USA, 106, 2009
4NP6
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BU of 4np6 by Molmil
Crystal Structure of Adenylate Kinase from Vibrio cholerae O1 biovar eltor
Descriptor: Adenylate kinase
Authors:Kim, Y, Zhou, M, Grimshaw, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2013-11-20
Release date:2013-12-18
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.004 Å)
Cite:Crystal Structure of Adenylate Kinase from Vibrio cholerae O1 biovar eltor
To be Published
5XJ5
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BU of 5xj5 by Molmil
Crystal structure of PlsY (YgiH), an integral membrane glycerol 3-phosphate acyltransferase - the monoacylglycerol form
Descriptor: (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, GLYCINE, Glycerol-3-phosphate acyltransferase, ...
Authors:Li, Z, Li, D.
Deposit date:2017-04-30
Release date:2017-12-06
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.481 Å)
Cite:Structural insights into the committed step of bacterial phospholipid biosynthesis.
Nat Commun, 8, 2017
5X6I
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BU of 5x6i by Molmil
Crystal structure of B. subtilis adenylate kinase variant
Descriptor: Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, CALCIUM ION, ...
Authors:Moon, S, Bae, E.
Deposit date:2017-02-22
Release date:2018-02-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and mutational analyses of psychrophilic and mesophilic adenylate kinases highlight the role of hydrophobic interactions in protein thermal stability.
Struct Dyn., 6, 2019
9DA9
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BU of 9da9 by Molmil
Crystal structure of GluN1/GluN2A agonist-binding domains in complex with 7CKA and glutamate
Descriptor: 7-Chlorokynurenic acid, GLUTAMIC ACID, Glutamate receptor ionotropic, ...
Authors:Bosco, J, Yates-Hansen, C.K, McClelland, L.J, Voronina, E, Hansen, K.B.
Deposit date:2024-08-22
Release date:2025-03-12
Last modified:2025-04-16
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:A galactose-based auto-expression system improves T7-inducible protein production in Escherichia coli.
Sci Rep, 15, 2025
3J16
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BU of 3j16 by Molmil
Models of ribosome-bound Dom34p and Rli1p and their ribosomal binding partners
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S24-A, ...
Authors:Becker, T, Franckenberg, S, Wickles, S, Shoemaker, C.J, Anger, A.M, Armache, J.-P, Sieber, H, Ungewickell, C, Berninghausen, O, Daberkow, I, Karcher, A, Thomm, M, Hopfner, K.-P, Green, R, Beckmann, R.
Deposit date:2011-12-12
Release date:2012-02-22
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Structural basis of highly conserved ribosome recycling in eukaryotes and archaea.
Nature, 482, 2012
5X6J
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BU of 5x6j by Molmil
Crystal structure of B. globisporus adenylate kinase variant
Descriptor: Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, ZINC ION
Authors:Moon, S, Bae, E.
Deposit date:2017-02-22
Release date:2018-02-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and mutational analyses of psychrophilic and mesophilic adenylate kinases highlight the role of hydrophobic interactions in protein thermal stability.
Struct Dyn., 6, 2019
3NDP
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BU of 3ndp by Molmil
Crystal structure of human AK4(L171P)
Descriptor: Adenylate kinase isoenzyme 4, SULFATE ION
Authors:Liu, R, Wang, Y, Wei, Z, Gong, W.
Deposit date:2010-06-07
Release date:2010-06-23
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of human adenylate kinase 4 (L171P) suggests the role of hinge region in protein domain motion
Biochem.Biophys.Res.Commun., 379, 2009
3J7A
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BU of 3j7a by Molmil
Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, small subunit
Descriptor: 18S ribosomal RNA, 40S ribosomal protein eS1, 40S ribosomal protein eS10, ...
Authors:Wong, W, Bai, X.C, Brown, A, Fernandez, I.S, Hanssen, E, Condron, M, Tan, Y.H, Baum, J, Scheres, S.H.W.
Deposit date:2014-06-03
Release date:2014-07-16
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine.
Elife, 3, 2014
3JBO
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BU of 3jbo by Molmil
Cryo-electron microscopy reconstruction of the Plasmodium falciparum 80S ribosome bound to P/E-tRNA
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein eS1, ...
Authors:Sun, M, Li, W, Blomqvist, K, Das, S, Hashem, Y, Dvorin, J.D, Frank, J.
Deposit date:2015-09-16
Release date:2015-10-14
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Dynamical features of the Plasmodium falciparum ribosome during translation.
Nucleic Acids Res., 43, 2015
3J7R
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BU of 3j7r by Molmil
Structure of the translating mammalian ribosome-Sec61 complex
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S.
Deposit date:2014-08-01
Release date:2014-09-03
Last modified:2024-11-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution.
Cell(Cambridge,Mass.), 157, 2014

238895

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