1XL9
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![BU of 1xl9 by Molmil](/molmil-images/mine/1xl9) | Crystal Structure of Dihydrodipicolinate Synthase DapA-2 (BA3935) from Bacillus Anthracis. | Descriptor: | dihydrodipicolinate synthase | Authors: | Blagova, E, Levdikov, V, Milioti, N, Fogg, M.J, Kalliomaa, A.K, Brannigan, J.A, Wilson, K.S, Wilkinson, A.J. | Deposit date: | 2004-09-30 | Release date: | 2005-10-04 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Crystal structure of dihydrodipicolinate synthase (BA3935) from Bacillus anthracis at 1.94 A resolution. Proteins, 62, 2006
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1XKY
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![BU of 1xky by Molmil](/molmil-images/mine/1xky) | Crystal Structure of Dihydrodipicolinate Synthase DapA-2 (BA3935) from Bacillus Anthracis at 1.94A Resolution. | Descriptor: | POTASSIUM ION, dihydrodipicolinate synthase | Authors: | Levdikov, V, Blagova, E, Fogg, M.J, Brannigan, J.A, Milioti, N, Wilkinson, A.J, Wilson, K.S. | Deposit date: | 2004-09-30 | Release date: | 2005-10-04 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Crystal structure of dihydrodipicolinate synthase (BA3935) from Bacillus anthracis at 1.94 A resolution Proteins, 62, 2006
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1W3N
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![BU of 1w3n by Molmil](/molmil-images/mine/1w3n) | Sulfolobus solfataricus 2-keto-3-deoxygluconate (KDG) aldolase complex with D-KDG | Descriptor: | 2-KETO-3-DEOXY GLUCONATE ALDOLASE, 3-DEOXY-D-ARABINO-HEXONIC ACID, GLYCEROL | Authors: | Theodossis, A, Walden, H, Westwick, E.J, Connaris, H, Lamble, H.J, Hough, D.W, Danson, M.J, Taylor, G.L. | Deposit date: | 2004-07-17 | Release date: | 2004-09-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The structural basis for substrate promiscuity in 2-keto-3-deoxygluconate aldolase from the Entner-Doudoroff pathway in Sulfolobus solfataricus. J. Biol. Chem., 279, 2004
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6H4E
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![BU of 6h4e by Molmil](/molmil-images/mine/6h4e) | Proteus mirabilis N-acetylneuraminate lyase | Descriptor: | Putative N-acetylneuraminate lyase, SULFATE ION | Authors: | North, R.A, Garcia-Bonete, M.J, Goyal, P, Katona, G, Dobson, R.C.J, Friemann, R. | Deposit date: | 2018-07-21 | Release date: | 2019-06-26 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.561 Å) | Cite: | The structure of Proteus mirabilis N-acetylneuraminate lyase reveals an intermolecular disulphide bond To Be Published
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6H2R
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3G0S
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![BU of 3g0s by Molmil](/molmil-images/mine/3g0s) | Dihydrodipicolinate synthase from Salmonella typhimurium LT2 | Descriptor: | CHLORIDE ION, Dihydrodipicolinate synthase, GLYCEROL, ... | Authors: | Osipiuk, J, Maltseva, N, Stam, J, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2009-01-28 | Release date: | 2009-02-10 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | X-ray crystal structure of dihydrodipicolinate synthase from Salmonella typhimurium LT2. To be Published
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1W3I
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![BU of 1w3i by Molmil](/molmil-images/mine/1w3i) | Sulfolobus solfataricus 2-keto-3-deoxygluconate (KDG) aldolase complex with pyruvate | Descriptor: | 2-KETO-3-DEOXY GLUCONATE ALDOLASE, GLYCEROL, PYRUVIC ACID | Authors: | Theodossis, A, Walden, H, Westwick, E.J, Connaris, H, Lamble, H.J, Hough, D.W, Danson, M.J, Taylor, G.L. | Deposit date: | 2004-07-15 | Release date: | 2004-09-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The structural basis for substrate promiscuity in 2-keto-3-deoxygluconate aldolase from the Entner-Doudoroff pathway in Sulfolobus solfataricus. J. Biol. Chem., 279, 2004
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1W37
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![BU of 1w37 by Molmil](/molmil-images/mine/1w37) | 2-keto-3-deoxygluconate(KDG) aldolase of Sulfolobus solfataricus | Descriptor: | 2-KETO-3-DEOXY GLUCONATE ALDOLASE, GLYCEROL, SODIUM ION | Authors: | Theodossis, A, Walden, H, Westwick, E.J, Connaris, H, Lamble, H.J, Hough, D.W, Danson, M.J, Taylor, G.L. | Deposit date: | 2004-07-13 | Release date: | 2004-09-02 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The structural basis for substrate promiscuity in 2-keto-3-deoxygluconate aldolase from the Entner-Doudoroff pathway in Sulfolobus solfataricus. J. Biol. Chem., 279, 2004
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1DHP
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![BU of 1dhp by Molmil](/molmil-images/mine/1dhp) | DIHYDRODIPICOLINATE SYNTHASE | Descriptor: | DIHYDRODIPICOLINATE SYNTHASE, POTASSIUM ION | Authors: | Mirwaldt, C, Korndoerfer, I, Huber, R. | Deposit date: | 1995-02-09 | Release date: | 1997-02-12 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The crystal structure of dihydrodipicolinate synthase from Escherichia coli at 2.5 A resolution. J.Mol.Biol., 246, 1995
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1W3T
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![BU of 1w3t by Molmil](/molmil-images/mine/1w3t) | Sulfolobus solfataricus 2-keto-3-deoxygluconate (KDG) aldolase complex with D-KDGal, D-Glyceraldehyde and pyruvate | Descriptor: | 2-KETO-3-DEOXY GLUCONATE ALDOLASE, 3-DEOXY-D-LYXO-HEXONIC ACID, D-Glyceraldehyde, ... | Authors: | Theodossis, A, Walden, H, Westwick, E.J, Connaris, H, Lamble, H.J, Hough, D.W, Danson, M.J, Taylor, G.L. | Deposit date: | 2004-07-19 | Release date: | 2004-09-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The structural basis for substrate promiscuity in 2-keto-3-deoxygluconate aldolase from the Entner-Doudoroff pathway in Sulfolobus solfataricus. J. Biol. Chem., 279, 2004
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3I7Q
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![BU of 3i7q by Molmil](/molmil-images/mine/3i7q) | Dihydrodipicolinate synthase mutant - K161A | Descriptor: | Dihydrodipicolinate synthase, GLYCEROL, PHOSPHATE ION, ... | Authors: | Dobson, R.C.J, Jameson, G.B, Gerrard, J.A, Soares da Costa, T.P. | Deposit date: | 2009-07-08 | Release date: | 2010-04-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | How essential is the 'essential' active-site lysine in dihydrodipicolinate synthase? Biochimie, 92, 2010
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6GSO
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![BU of 6gso by Molmil](/molmil-images/mine/6gso) | Sulfolobus solfataricus 2-keto-3-deoxygluconate aldolase Y132V,T157C variant | Descriptor: | 1,2-ETHANEDIOL, 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase, GLYCEROL | Authors: | Crennell, S.J, Danson, M.J, Royer, S. | Deposit date: | 2018-06-15 | Release date: | 2019-06-26 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Sulfolobus solfataricus 2-keto-3-deoxygluconate aldolase Y132V,T157C variant To Be Published
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6GV2
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![BU of 6gv2 by Molmil](/molmil-images/mine/6gv2) | Sulfolobus solfataricus 2-keto-3-deoxygluconate aldolase Y103F,Y130F,A198F variant in complex with L-2-keto, 3-deoxy-galactonate | Descriptor: | 1,2-ETHANEDIOL, 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase, 3-DEOXY-D-ARABINO-HEXONIC ACID, ... | Authors: | Crennell, S.J, Danson, M.J, Royer, S. | Deposit date: | 2018-06-20 | Release date: | 2019-07-03 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.101 Å) | Cite: | Sulfolobus solfataricus 2-keto-3-deoxygluconate aldolase Y132V,T157C variant To Be Published
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1FDY
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![BU of 1fdy by Molmil](/molmil-images/mine/1fdy) | N-ACETYLNEURAMINATE LYASE IN COMPLEX WITH HYDROXYPYRUVATE | Descriptor: | 3-HYDROXYPYRUVIC ACID, N-ACETYLNEURAMINATE LYASE | Authors: | Lawrence, M.C, Barbosa, J.A.R.G, Smith, B.J, Hall, N.E, Pilling, P.A, Ooi, H.C, Marcuccio, S.M. | Deposit date: | 1996-07-08 | Release date: | 1997-10-22 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structure and mechanism of a sub-family of enzymes related to N-acetylneuraminate lyase. J.Mol.Biol., 266, 1997
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1FDZ
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![BU of 1fdz by Molmil](/molmil-images/mine/1fdz) | N-ACETYLNEURAMINATE LYASE IN COMPLEX WITH PYRUVATE VIA BOROHYDRIDE REDUCTION | Descriptor: | N-ACETYLNEURAMINATE LYASE, PYRUVIC ACID | Authors: | Lawrence, M.C, Barbosa, J.A.R.G, Smith, B.J, Hall, N.E, Pilling, P.A, Ooi, H.C, Marcuccio, S.M. | Deposit date: | 1996-07-08 | Release date: | 1997-10-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure and mechanism of a sub-family of enzymes related to N-acetylneuraminate lyase. J.Mol.Biol., 266, 1997
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1YXD
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![BU of 1yxd by Molmil](/molmil-images/mine/1yxd) | Structure of E. coli dihydrodipicolinate synthase bound with allosteric inhibitor (S)-lysine to 2.0 A | Descriptor: | CHLORIDE ION, LYSINE, POTASSIUM ION, ... | Authors: | Dobson, R.C.J, Griffin, M.D.W, Jameson, G.B, Gerrard, J.A. | Deposit date: | 2005-02-20 | Release date: | 2005-08-02 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance. Acta Crystallogr.,Sect.D, 61, 2005
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3I7R
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![BU of 3i7r by Molmil](/molmil-images/mine/3i7r) | Dihydrodipicolinate synthase - K161R | Descriptor: | CHLORIDE ION, Dihydrodipicolinate synthase, GLYCEROL, ... | Authors: | Dobson, R.C.J, Jameson, G.B, Gerrard, J.A, Soares da Costa, T.P. | Deposit date: | 2009-07-08 | Release date: | 2010-04-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | How essential is the 'essential' active-site lysine in dihydrodipicolinate synthase? Biochimie, 92, 2010
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3HIJ
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![BU of 3hij by Molmil](/molmil-images/mine/3hij) | Crystal structure of dihydrodipicolinate synthase from Bacillus anthracis in complex with its substrate, pyruvate | Descriptor: | Dihydrodipicolinate synthase, GLYCEROL, SODIUM ION | Authors: | Voss, J.E, Scally, S.W, Dobson, R.C.J, Perugini, M.A. | Deposit date: | 2009-05-20 | Release date: | 2009-11-24 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Substrate-mediated Stabilization of a Tetrameric Drug Target Reveals Achilles Heel in Anthrax. J.Biol.Chem., 285, 2010
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1XXX
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![BU of 1xxx by Molmil](/molmil-images/mine/1xxx) | Crystal structure of Dihydrodipicolinate Synthase (DapA, Rv2753c) from Mycobacterium tuberculosis | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CHLORIDE ION, Dihydrodipicolinate synthase, ... | Authors: | Kefala, G, Panjikar, S, Janowski, R, Weiss, M.S, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2004-11-09 | Release date: | 2006-02-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis. Biochem.J., 411, 2008
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3I7S
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![BU of 3i7s by Molmil](/molmil-images/mine/3i7s) | Dihydrodipicolinate synthase mutant - K161A - with the substrate pyruvate bound in the active site. | Descriptor: | Dihydrodipicolinate synthase, GLYCEROL, PHOSPHATE ION, ... | Authors: | Dobson, R.C.J, Jameson, G.B, Gerrard, J.A, Soares da Costa, T.P. | Deposit date: | 2009-07-08 | Release date: | 2010-04-14 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | How essential is the 'essential' active-site lysine in dihydrodipicolinate synthase? Biochimie, 92, 2010
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3FLU
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3IRD
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1F6K
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![BU of 1f6k by Molmil](/molmil-images/mine/1f6k) | CRYSTAL STRUCTURE ANALYSIS OF N-ACETYLNEURAMINATE LYASE FROM HAEMOPHILUS INFLUENZAE: CRYSTAL FORM II | Descriptor: | GLYCEROL, N-ACETYLNEURAMINATE LYASE, SULFATE ION | Authors: | Barbosa, J.A.R.G, Smith, B.J, DeGori, R, Lawrence, M.C. | Deposit date: | 2000-06-21 | Release date: | 2000-12-20 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Active site modulation in the N-acetylneuraminate lyase sub-family as revealed by the structure of the inhibitor-complexed Haemophilus influenzae enzyme. J.Mol.Biol., 303, 2000
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1YXC
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![BU of 1yxc by Molmil](/molmil-images/mine/1yxc) | Structure of E. coli dihydrodipicolinate synthase to 1.9 A | Descriptor: | CHLORIDE ION, POTASSIUM ION, dihydrodipicolinate synthase | Authors: | Dobson, R.C.J, Griffin, M.D.W, Jameson, G.B, Gerrard, J.A. | Deposit date: | 2005-02-20 | Release date: | 2005-08-02 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The crystal structures of native and (S)-lysine-bound dihydrodipicolinate synthase from Escherichia coli with improved resolution show new features of biological significance. Acta Crystallogr.,Sect.D, 61, 2005
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1F5Z
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