1SE6
| Crystal Structure of Streptomyces Coelicolor A3(2) CYP158A2 from antibiotic biosynthetic pathways | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, PROTOPORPHYRIN IX CONTAINING FE, SPERMINE (FULLY PROTONATED FORM), ... | Authors: | Zhao, B, Lamb, D.C, Lei, L, Sundaramoorthy, M, Podust, L.M, Waterman, M.R. | Deposit date: | 2004-02-16 | Release date: | 2005-01-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Binding of Two Flaviolin Substrate Molecules, Oxidative Coupling, and Crystal Structure of Streptomyces coelicolor A3(2) Cytochrome P450 158A2. J.Biol.Chem., 280, 2005
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1T93
| Evidence for Multiple Substrate Recognition and Molecular Mechanism of C-C reaction by Cytochrome P450 CYP158A2 from Streptomyces Coelicolor A3(2) | Descriptor: | FLAVIOLIN, PROTOPORPHYRIN IX CONTAINING FE, putative cytochrome P450 | Authors: | Zhao, B, Sundaramoorthy, M, Waterman, M.R. | Deposit date: | 2004-05-14 | Release date: | 2005-01-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Binding of Two Flaviolin Substrate Molecules, Oxidative Coupling, and Crystal Structure of Streptomyces coelicolor A3(2) Cytochrome P450 158A2. J.Biol.Chem., 280, 2005
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1YRC
| X-ray Crystal Structure of hydrogenated Cytochrome P450cam | Descriptor: | CAMPHOR, Cytochrome P450-cam, POTASSIUM ION, ... | Authors: | Meilleur, F, Dauvergne, M.-T, Schlichting, I, Myles, D.A.A. | Deposit date: | 2005-02-03 | Release date: | 2005-02-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Production and X-ray crystallographic analysis of fully deuterated cytochrome P450cam. Acta Crystallogr.,Sect.D, 61, 2005
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1YRD
| X-ray crystal structure of PERDEUTERATED Cytochrome P450cam | Descriptor: | CAMPHOR, Cytochrome P450-cam, POTASSIUM ION, ... | Authors: | Meilleur, F, Dauvergne, M.-T, Schlichting, I, Myles, D.A.A. | Deposit date: | 2005-02-03 | Release date: | 2005-02-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Production and X-ray crystallographic analysis of fully deuterated cytochrome P450cam. Acta Crystallogr.,Sect.D, 61, 2005
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1UYU
| Xenon COMPLEX OF wildtype P450CAM FROM PSEUDOMONAS PUTIDA | Descriptor: | CAMPHOR, CYTOCHROME P450-CAM, POTASSIUM ION, ... | Authors: | Wade, R.C, Winn, P.J, Schlichting, I, Sudarko, X. | Deposit date: | 2004-03-02 | Release date: | 2005-03-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A Survey of Active Site Access Channels in Cytochromes P450 J.Inorg.Biochem., 98, 2004
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1Z8P
| Ferrous dioxygen complex of the A245S cytochrome P450eryF | Descriptor: | 6-DEOXYERYTHRONOLIDE B, 6-deoxyerythronolide B hydroxylase, OXYGEN MOLECULE, ... | Authors: | Poulos, T.L, Nagano, S. | Deposit date: | 2005-03-31 | Release date: | 2005-04-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structures of the ferrous dioxygen complex of wild-type cytochrome P450eryF and its mutants, A245S and A245T: investigation of the proton transfer system in P450eryF. J.Biol.Chem., 280, 2005
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1Z8Q
| Ferrous dioxygen complex of the A245T cytochrome P450eryF | Descriptor: | 6-DEOXYERYTHRONOLIDE B, 6-deoxyerythronolide B hydroxylase, OXYGEN MOLECULE, ... | Authors: | Nagano, S, Cupp-Vickery, J.R, Poulos, T.L. | Deposit date: | 2005-03-31 | Release date: | 2005-04-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of the ferrous dioxygen complex of wild-type cytochrome P450eryF and its mutants, A245S and A245T: investigation of the proton transfer system in P450eryF. J.Biol.Chem., 280, 2005
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1Z8O
| Ferrous dioxygen complex of the wild-type cytochrome P450eryF | Descriptor: | 6-DEOXYERYTHRONOLIDE B, 6-deoxyerythronolide B hydroxylase, OXYGEN MOLECULE, ... | Authors: | Nagano, S, Cupp-Vickery, J.R, Poulos, T.L. | Deposit date: | 2005-03-31 | Release date: | 2005-04-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structures of the ferrous dioxygen complex of wild-type cytochrome P450eryF and its mutants, A245S and A245T: investigation of the proton transfer system in P450eryF. J.Biol.Chem., 280, 2005
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1T2B
| Crystal Structure of cytochrome P450cin complexed with its substrate 1,8-cineole | Descriptor: | 1,3,3-TRIMETHYL-2-OXABICYCLO[2.2.2]OCTANE, P450cin, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Meharenna, Y.T, Li, H, Hawkes, D.B, Pearson, A.G, De Voss, J, Poulos, T.L. | Deposit date: | 2004-04-20 | Release date: | 2005-04-26 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure of P450cin in a complex with its substrate, 1,8-cineole, a close structural homologue to D-camphor, the substrate for P450cam Biochemistry, 43, 2004
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2A1O
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2A1N
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2A1M
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1Z11
| Crystal Structure of Human Microsomal P450 2A6 with Methoxsalen Bound | Descriptor: | METHOXSALEN, PROTOPORPHYRIN IX CONTAINING FE, cytochrome P450, ... | Authors: | Yano, J.K, Hsu, M.H, Griffin, K.J, Stout, C.D, Johnson, E.F. | Deposit date: | 2005-03-02 | Release date: | 2005-08-16 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen Nat.Struct.Mol.Biol., 12, 2005
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1Z10
| Crystal Structure of Human Microsomal P450 2A6 with Coumarin Bound | Descriptor: | COUMARIN, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Yano, J.K, Hsu, M.H, Griffin, K.J, Stout, C.D, Johnson, E.F. | Deposit date: | 2005-03-02 | Release date: | 2005-08-16 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen Nat.Struct.Mol.Biol., 12, 2005
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2D09
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2D0E
| Substrate assited in Oxygen Activation in Cytochrome P450 158A2 | Descriptor: | 2-HYDROXYNAPHTHOQUINONE, PROTOPORPHYRIN IX CONTAINING FE, putative cytochrome P450 | Authors: | Zhao, B, Waterman, M.R. | Deposit date: | 2005-08-02 | Release date: | 2005-10-25 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Role of active site water molecules and substrate hydroxyl groups in oxygen activation by cytochrome P450 158A2: a new mechanism of proton transfer J.Biol.Chem., 280, 2005
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2F9Q
| Crystal Structure of Human Cytochrome P450 2D6 | Descriptor: | Cytochrome P450 2D6, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | Authors: | Rowland, P. | Deposit date: | 2005-12-06 | Release date: | 2005-12-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.002 Å) | Cite: | Crystal Structure of Human Cytochrome P450 2D6 J.Biol.Chem., 281, 2006
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2BDM
| Structure of Cytochrome P450 2B4 with Bound Bifonazole | Descriptor: | 1-[PHENYL-(4-PHENYLPHENYL)-METHYL]IMIDAZOLE, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B4, ... | Authors: | Zhao, Y, White, M.A, Muralidhara, B.K, Sun, L, Halpert, J.R, Stout, C.D. | Deposit date: | 2005-10-20 | Release date: | 2005-12-27 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of microsomal cytochrome P450 2B4 complexed with the antifungal drug bifonazole: insight into P450 conformational plasticity and membrane interaction. J.Biol.Chem., 281, 2006
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1YQO
| T268A mutant heme domain of flavocytochrome P450 BM3 | Descriptor: | Bifunctional P-450:NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Clark, J.P, Miles, C.S, Mowat, C.G, Walkinshaw, M.D, Reid, G.A, Daff, S.N, Chapman, S.K. | Deposit date: | 2005-02-02 | Release date: | 2006-01-31 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The role of Thr268 and Phe393 in cytochrome P450 BM3. J.Inorg.Biochem., 100, 2006
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1YQP
| T268N mutant cytochrome domain of flavocytochrome P450 BM3 | Descriptor: | Bifunctional P-450:NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Clark, J.P, Miles, C.S, Mowat, C.G, Walkinshaw, M.D, Reid, G.A, Daff, S.N, Chapman, S.K. | Deposit date: | 2005-02-02 | Release date: | 2006-01-31 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The role of Thr268 and Phe393 in cytochrome P450 BM3. J.Inorg.Biochem., 100, 2006
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2FE6
| P450CAM from Pseudomonas putida reconstituted with manganic protoporphyrin IX | Descriptor: | Cytochrome P450-cam, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING MN | Authors: | von Koenig, K, Makris, T.M, Sligar, S.G, Schlichting, I. | Deposit date: | 2005-12-15 | Release date: | 2006-03-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The status of high-valent metal oxo complexes in the P450 cytochromes. J.Inorg.Biochem., 100, 2006
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2FER
| P450CAM from Pseudomonas putida reconstituted with manganic protoporphyrin IX | Descriptor: | Cytochrome P450-cam, POTASSIUM ION, PROTOPORPHYRIN IX CONTAINING MN | Authors: | von Koenig, K, Makris, T.M, Sligar, S.G, Schlichting, I. | Deposit date: | 2005-12-16 | Release date: | 2006-03-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The status of high-valent metal oxo complexes in the P450 cytochromes. J.Inorg.Biochem., 100, 2006
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2FEU
| P450CAM from Pseudomonas putida reconstituted with manganic protoporphyrin IX | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, Cytochrome P450-cam, ... | Authors: | von Koenig, K, Makris, T.M, Sligar, S.G, Schlichting, I. | Deposit date: | 2005-12-16 | Release date: | 2006-03-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The status of high-valent metal oxo complexes in the P450 cytochromes. J.Inorg.Biochem., 100, 2006
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2C6H
| Crystal structure of YC-17-bound cytochrome P450 PikC (CYP107L1) | Descriptor: | 4-{[4-(DIMETHYLAMINO)-3-HYDROXY-6-METHYLTETRAHYDRO-2H-PYRAN-2-YL]OXY}-12-ETHYL-3,5,7,11-TETRAMETHYLOXACYCLODODEC-9-ENE-2,8-DIONE, CYTOCHROME P450 MONOOXYGENASE, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Sherman, D.H, Li, S, Yermalitskaya, L.V, Kim, Y, Smith, J.A, Waterman, M.R, Podust, L.M. | Deposit date: | 2005-11-09 | Release date: | 2006-07-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | The Structural Basis for Substrate Anchoring, Active Site Selectivity, and Product Formation by P450 Pikc from Streptomyces Venezuelae. J.Biol.Chem., 281, 2006
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2BVJ
| Ligand-free structure of cytochrome P450 PikC (CYP107L1) | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, BETA-MERCAPTOETHANOL, CYTOCHROME P450 MONOOXYGENASE, ... | Authors: | Sherman, D.H, Li, S, Yermalitskaya, L.V, Kim, Y, Smith, J.A, Waterman, M.R, Podust, L.M. | Deposit date: | 2005-06-28 | Release date: | 2006-07-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The Structural Basis for Substrate Anchoring, Active Site Selectivity, and Product Formation by P450 Pikc from Streptomyces Venezuelae. J.Biol.Chem., 281, 2006
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