5WFN
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![BU of 5wfn by Molmil](/molmil-images/mine/5wfn) | Revised model of leiomodin 2-mediated actin regulation (alternate refinement of PDB 4RWT) | Descriptor: | Actin-5C, Leiomodin-2, MAGNESIUM ION, ... | Authors: | Yurtsever, Z, Eck, M.J, Dominguez, R. | Deposit date: | 2017-07-12 | Release date: | 2017-08-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of leiomodin 2 in complex with actin: a structural and functional reexamination Biophys.J., 113, 2017
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5H9S
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![BU of 5h9s by Molmil](/molmil-images/mine/5h9s) | Crystal Structure of Human Galectin-7 in Complex with TAZTDG | Descriptor: | (2~{S},3~{R},4~{S},5~{R},6~{R})-2-[(2~{S},3~{R},4~{S},5~{R},6~{R})-4-[4-(3-fluorophenyl)-1,2,3-triazol-1-yl]-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]sulfanyl-6-(hydroxymethyl)oxane-3,4,5-triol, Galectin-7 | Authors: | Hsieh, T.J, Lin, H.Y, Lin, C.H. | Deposit date: | 2015-12-29 | Release date: | 2016-06-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.821 Å) | Cite: | Dual thio-digalactoside-binding modes of human galectins as the structural basis for the design of potent and selective inhibitors Sci Rep, 6, 2016
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5WKU
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![BU of 5wku by Molmil](/molmil-images/mine/5wku) | Structure of an acid sensing ion channel in a resting state with barium | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, ... | Authors: | Yoder, N, Gouaux, E. | Deposit date: | 2017-07-25 | Release date: | 2018-03-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Gating mechanisms of acid-sensing ion channels. Nature, 555, 2018
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5HF9
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![BU of 5hf9 by Molmil](/molmil-images/mine/5hf9) | Crystal structure of human acetylcholinesterase in complex with paraoxon and HI6 | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Franklin, M.F, Rudolph, M.J, Ginter, C, Cassidy, M.S, Cheung, J. | Deposit date: | 2016-01-06 | Release date: | 2016-06-22 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structures of paraoxon-inhibited human acetylcholinesterase reveal perturbations of the acyl loop and the dimer interface. Proteins, 84, 2016
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5WMI
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![BU of 5wmi by Molmil](/molmil-images/mine/5wmi) | Arabidopsis thaliana Prephenate Aminotransferase mutant- T84V | Descriptor: | 2-OXOGLUTARIC ACID, Bifunctional aspartate aminotransferase and glutamate/aspartate-prephenate aminotransferase | Authors: | Jez, J.M, Holland, C.K. | Deposit date: | 2017-07-28 | Release date: | 2018-08-08 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for substrate recognition and inhibition of prephenate aminotransferase from Arabidopsis. Plant J., 94, 2018
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5WN5
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![BU of 5wn5 by Molmil](/molmil-images/mine/5wn5) | APE1 exonuclease substrate complex with a C/T mismatch and Mn2+ | Descriptor: | 1,2-ETHANEDIOL, DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*(DV3))-3'), DNA (5'-D(*GP*GP*AP*TP*CP*CP*GP*TP*CP*GP*AP*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... | Authors: | Freudenthal, B.D, Whitaker, A.M. | Deposit date: | 2017-07-31 | Release date: | 2018-02-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Molecular snapshots of APE1 proofreading mismatches and removing DNA damage. Nat Commun, 9, 2018
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5GAH
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![BU of 5gah by Molmil](/molmil-images/mine/5gah) | RNC in complex with SRP with detached NG domain | Descriptor: | 1A9L SS, 23S rRNA, 50S ribosomal protein L10, ... | Authors: | Jomaa, A, Boehringer, D, Leibundgut, M, Ban, N. | Deposit date: | 2015-11-26 | Release date: | 2016-01-27 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon. Nat Commun, 7, 2016
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5GL1
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![BU of 5gl1 by Molmil](/molmil-images/mine/5gl1) | Structure of RyR1 in an open state | Descriptor: | Peptidyl-prolyl cis-trans isomerase FKBP1A, Ryanodine receptor 1, ZINC ION | Authors: | Bai, X.C, Yan, Z, Wu, J.P, Yan, N. | Deposit date: | 2016-07-07 | Release date: | 2016-08-24 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (5.7 Å) | Cite: | The Central domain of RyR1 is the transducer for long-range allosteric gating of channel opening Cell Res., 26, 2016
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5GQ0
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![BU of 5gq0 by Molmil](/molmil-images/mine/5gq0) | |
5WXP
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![BU of 5wxp by Molmil](/molmil-images/mine/5wxp) | Crystal structure of uPA in complex with upain-2-3-W3A | Descriptor: | ALANINE, CYSTEINE, Urokinase-type plasminogen activator chain B, ... | Authors: | Jiang, L, Huang, M. | Deposit date: | 2017-01-08 | Release date: | 2018-07-11 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Cleavage of peptidic inhibitors by target protease is caused by peptide conformational transition. Biochim. Biophys. Acta, 1862, 2018
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5Z3F
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![BU of 5z3f by Molmil](/molmil-images/mine/5z3f) | Glycosidase E335A in complex with glucose | Descriptor: | CITRIC ACID, GLYCEROL, Glycoside hydrolase 15-related protein, ... | Authors: | Tanaka, Y, Chen, M, Tagami, T, Yao, M, Kimura, A. | Deposit date: | 2018-01-05 | Release date: | 2019-05-15 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Structural insights reveal the second base catalyst of isomaltose glucohydrolase. Febs J., 289, 2022
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5GTH
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![BU of 5gth by Molmil](/molmil-images/mine/5gth) | Native XFEL structure of photosystem II (dark dataset) | Descriptor: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, ... | Authors: | Suga, M, Shen, J.R. | Deposit date: | 2016-08-20 | Release date: | 2017-03-15 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Light-induced structural changes and the site of O=O bond formation in PSII caught by XFEL. Nature, 543, 2017
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5GWK
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![BU of 5gwk by Molmil](/molmil-images/mine/5gwk) | Human topoisomerase IIalpha in complex with DNA and etoposide | Descriptor: | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(P*AP*GP*CP*CP*GP*AP*GP*C)-3'), DNA (5'-D(P*TP*GP*CP*AP*GP*CP*TP*CP*GP*GP*CP*T)-3'), ... | Authors: | Wang, Y.R, Wu, C.C, Chan, N.L. | Deposit date: | 2016-09-12 | Release date: | 2017-08-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.152 Å) | Cite: | Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry Nucleic Acids Res., 45, 2017
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5GZ6
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![BU of 5gz6 by Molmil](/molmil-images/mine/5gz6) | Structure of D-amino acid dehydrogenase in complex with NADPH and 2-keto-6-aminocapronic acid | Descriptor: | 6-azanyl-2-oxidanylidene-hexanoic acid, ACETATE ION, Meso-diaminopimelate D-dehydrogenase, ... | Authors: | Sakuraba, H, Seto, T, Hayashi, J, Akita, H, Yoneda, K, Ohshima, T. | Deposit date: | 2016-09-26 | Release date: | 2017-04-12 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.74 Å) | Cite: | Structure-Based Engineering of an Artificially Generated NADP+-Dependent d-Amino Acid Dehydrogenase Appl. Environ. Microbiol., 83, 2017
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5H47
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![BU of 5h47 by Molmil](/molmil-images/mine/5h47) | Crystal structure of AOL complexed with 2-MeSe-Fuc | Descriptor: | Uncharacterized protein, methyl 6-deoxy-2-Se-methyl-2-seleno-alpha-L-galactopyranoside | Authors: | Kato, R, Nishikawa, Y, Makyio, H. | Deposit date: | 2016-10-31 | Release date: | 2017-01-25 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Synthesis of seleno-fucose compounds and their application to the X-ray structural determination of carbohydrate-lectin complexes using single/multi-wavelength anomalous dispersion phasing Bioorg. Med. Chem., 25, 2017
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5G6A
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![BU of 5g6a by Molmil](/molmil-images/mine/5g6a) | Structure of Bacillus subtilis Nitric Oxide Synthase in complex with 7-((3-Fluorophenethylamino)ethyl)quinolin-2-amine | Descriptor: | 5,6,7,8-TETRAHYDROBIOPTERIN, 7-[2-[2-(3-fluorophenyl)ethylamino]ethyl]quinolin-2-amine, CHLORIDE ION, ... | Authors: | Holden, J.K, Poulos, T.L. | Deposit date: | 2016-06-18 | Release date: | 2016-09-21 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Targeting Bacterial Nitric Oxide Synthase with Aminoquinoline-Based Inhibitors. Biochemistry, 55, 2016
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5H2M
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![BU of 5h2m by Molmil](/molmil-images/mine/5h2m) | A three dimensional movie of structural changes in bacteriorhodopsin: structure obtained 13.8 us after photoexcitation | Descriptor: | 2,3-DI-PHYTANYL-GLYCEROL, Bacteriorhodopsin, DECANE, ... | Authors: | Royant, A, Nango, E, Nakane, T, Tanaka, T, Arima, T, Neutze, R, Iwata, S. | Deposit date: | 2016-10-15 | Release date: | 2016-12-21 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A three-dimensional movie of structural changes in bacteriorhodopsin Science, 354, 2016
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5Z84
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![BU of 5z84 by Molmil](/molmil-images/mine/5z84) | The structure of azide-bound cytochrome c oxidase determined using the crystals exposed to 20 mM azide solution for 4 days | Descriptor: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ... | Authors: | Shimada, A, Hatano, K, Tadehara, H, Tsukihara, T. | Deposit date: | 2018-01-31 | Release date: | 2018-08-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | X-ray structural analyses of azide-bound cytochromecoxidases reveal that the H-pathway is critically important for the proton-pumping activity. J. Biol. Chem., 293, 2018
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5Z85
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![BU of 5z85 by Molmil](/molmil-images/mine/5z85) | The structure of azide-bound cytochrome c oxidase determined using the another batch crystals exposed to 20 mM azide solution for 2 days | Descriptor: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ... | Authors: | Shimada, A, Hatano, K, Tadehara, H, Tsukihara, T. | Deposit date: | 2018-01-31 | Release date: | 2018-08-15 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | X-ray structural analyses of azide-bound cytochromecoxidases reveal that the H-pathway is critically important for the proton-pumping activity. J. Biol. Chem., 293, 2018
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5GAE
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![BU of 5gae by Molmil](/molmil-images/mine/5gae) | RNC in complex with a translocating SecYEG | Descriptor: | 23S rRNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... | Authors: | Jomaa, A, Boehringer, D, Leibundgut, M, Ban, N. | Deposit date: | 2015-11-25 | Release date: | 2016-01-27 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon. Nat Commun, 7, 2016
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5ZE0
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![BU of 5ze0 by Molmil](/molmil-images/mine/5ze0) | Hairpin Forming Complex, RAG1/2-Nicked(with Dideoxy) 12RSS/23RSS complex in Mg2+ | Descriptor: | 1,2-ETHANEDIOL, DNA (30-MER), DNA (39-MER), ... | Authors: | Kim, M.S, Chuenchor, W, Chen, X, Gellert, M, Yang, W. | Deposit date: | 2018-02-25 | Release date: | 2018-04-25 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Cracking the DNA Code for V(D)J Recombination Mol. Cell, 70, 2018
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5ZHH
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![BU of 5zhh by Molmil](/molmil-images/mine/5zhh) | |
5ZI5
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![BU of 5zi5 by Molmil](/molmil-images/mine/5zi5) | |
5ZET
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![BU of 5zet by Molmil](/molmil-images/mine/5zet) | M. smegmatis P/P state 50S ribosomal subunit | Descriptor: | 23S rRNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... | Authors: | Mishra, S, Ahmed, T, Tyagi, A, Shi, J, Bhushan, S. | Deposit date: | 2018-02-28 | Release date: | 2018-09-26 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structures of Mycobacterium smegmatis 70S ribosomes in complex with HPF, tmRNA, and P-tRNA. Sci Rep, 8, 2018
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5ZJI
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![BU of 5zji by Molmil](/molmil-images/mine/5zji) | Structure of photosystem I supercomplex with light-harvesting complexes I and II | Descriptor: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, ... | Authors: | Pan, X.W, Ma, J, Su, X.D, Cao, P, Liu, Z.F, Zhang, X.Z, Li, M. | Deposit date: | 2018-03-20 | Release date: | 2018-06-20 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of the maize photosystem I supercomplex with light-harvesting complexes I and II. Science, 360, 2018
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