1WUA
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![BU of 1wua by Molmil](/molmil-images/mine/1wua) | The structure of Aplyronine A-actin complex | Descriptor: | (8R,9R,10R,11R,14S,18S,20S,24S)-24-{(1R,2S,3R,6R,7R,8R,9S,10E)-8-(ACETYLOXY)-6-[(N,N-DIMETHYLALANYL)OXY]-11-[FORMYL(MET HYL)AMINO]-2-HYDROXY-1,3,7,9-TETRAMETHYLUNDEC-10-ENYL}-10-HYDROXY-14,20-DIMETHOXY-9,11,15,18-TETRAMETHYL-2-OXOOXACYCLOTE TRACOSA-3,5,15,21-TETRAEN-8-YL N,N,O-TRIMETHYLSERINATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... | Authors: | Hirata, K, Muraoka, S, Suenaga, K, Kuroda, T, Kato, K, Tanaka, H, Yamamoto, M, Takata, M, Yamada, K, Kigoshi, H. | Deposit date: | 2004-12-03 | Release date: | 2006-02-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure basis for antitumor effect of aplyronine a J.Mol.Biol., 356, 2006
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6F95
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![BU of 6f95 by Molmil](/molmil-images/mine/6f95) | |
5MV7
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![BU of 5mv7 by Molmil](/molmil-images/mine/5mv7) | Structure of human Myosin 7b C-terminal MyTH4-FERM MF2 domain | Descriptor: | SULFATE ION, TRIS(HYDROXYETHYL)AMINOMETHANE, Unconventional myosin-VIIb | Authors: | Planelles-Herrero, V.J, Sourigues, Y, Titus, M.A, Houdusse, A. | Deposit date: | 2017-01-15 | Release date: | 2017-07-05 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.44 Å) | Cite: | Myosin 7 and its adaptors link cadherins to actin. Nat Commun, 8, 2017
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5MV9
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![BU of 5mv9 by Molmil](/molmil-images/mine/5mv9) | Structure of human Myosin 7a C-terminal MyTH4-FERM domain in complex with harmonin-a PDZ3 domain | Descriptor: | ACETATE ION, Unconventional myosin-VIIa, cDNA FLJ51329, ... | Authors: | Yu, I, Sourigues, Y, Titus, M.A, Houdusse, A. | Deposit date: | 2017-01-16 | Release date: | 2017-07-05 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Myosin 7 and its adaptors link cadherins to actin. Nat Commun, 8, 2017
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5MV8
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![BU of 5mv8 by Molmil](/molmil-images/mine/5mv8) | Structure of human Myosin 7b C-terminal MyTH4-FERM domain in complex with harmonin-a PDZ3 domain | Descriptor: | GLYCEROL, MAGNESIUM ION, Unconventional myosin-VIIb, ... | Authors: | Yu, I, Sourigues, Y, Titus, M.A, Houdusse, A. | Deposit date: | 2017-01-16 | Release date: | 2017-07-05 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Myosin 7 and its adaptors link cadherins to actin. Nat Commun, 8, 2017
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3FER
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![BU of 3fer by Molmil](/molmil-images/mine/3fer) | Crystal structure of n-terminal actin-binding domain from human filamin b (tandem ch-domains). northeast structural genomics consortium target hr5571a. | Descriptor: | ACETIC ACID, Filamin-B | Authors: | Kuzin, A.P, Abashidze, M, Seetharaman, R, Shastry, R, Sahdev, S, Ciccosanti, C, Xiao, R, Everett, J.K, Huang, Y, Acton, T, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2008-11-30 | Release date: | 2009-01-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of n-terminal actin-binding domain from human filamin b (tandem ch-domains). northeast structural genomics consortium target hr5571a. To be Published
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1M4J
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![BU of 1m4j by Molmil](/molmil-images/mine/1m4j) | CRYSTAL STRUCTURE OF THE N-TERMINAL ADF-H DOMAIN OF MOUSE TWINFILIN ISOFORM-1 | Descriptor: | A6 gene product | Authors: | Paavilainen, V.O, Merckel, M.C, Falck, S, Ojala, P.J, Pohl, E, Wilmanns, M, Lappalainen, P. | Deposit date: | 2002-07-03 | Release date: | 2002-11-13 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural Conservation Between the Actin Monomer-binding Sites of Twinfilin and Actin-depolymerizing Factor (ADF)/Cofilin J.Biol.Chem., 277, 2002
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1K4Z
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![BU of 1k4z by Molmil](/molmil-images/mine/1k4z) | C-terminal Domain of Cyclase Associated Protein | Descriptor: | Adenylyl Cyclase-Associated Protein | Authors: | Rozwarski, D.A, Fedorov, A.A, Dodatko, T, Almo, S.C, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2001-10-09 | Release date: | 2002-03-13 | Last modified: | 2021-02-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of the actin binding domain of the cyclase-associated protein Biochemistry, 43, 2004
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2JSW
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![BU of 2jsw by Molmil](/molmil-images/mine/2jsw) | Solution Structure of the R13 Domain of Talin | Descriptor: | Talin-1 | Authors: | Goult, B.T, Gingras, A.R, Bate, N, Critchley, D.R.C, Barsukov, I.L. | Deposit date: | 2007-07-17 | Release date: | 2008-01-29 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | The structure of the C-terminal actin-binding domain of talin. Embo J., 27, 2007
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4OZU
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![BU of 4ozu by Molmil](/molmil-images/mine/4ozu) | Crystal Structure of WD40 domain from Toxoplasma gondii coronin | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, Coronin | Authors: | Kallio, J.P, Kursula, I. | Deposit date: | 2014-02-19 | Release date: | 2014-08-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structure of Toxoplasma gondii coronin, an actin-binding protein that relocalizes to the posterior pole of invasive parasites and contributes to invasion and egress. Faseb J., 28, 2014
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5YED
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![BU of 5yed by Molmil](/molmil-images/mine/5yed) | Crystal structure of LokiProfilin1 | Descriptor: | Uncharacterized protein | Authors: | Robinson, R.C, Akil, C. | Deposit date: | 2017-09-16 | Release date: | 2018-09-19 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Genomes of Asgard archaea encode profilins that regulate actin. Nature, 562, 2018
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7NIP
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![BU of 7nip by Molmil](/molmil-images/mine/7nip) | |
6RSQ
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![BU of 6rsq by Molmil](/molmil-images/mine/6rsq) | Helical folded domain of mouse CAP1 | Descriptor: | Adenylyl cyclase-associated protein 1, GLYCEROL | Authors: | Kotila, T, Kogan, K, Lappalainen, P. | Deposit date: | 2019-05-22 | Release date: | 2019-11-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Mechanism of synergistic actin filament pointed end depolymerization by cyclase-associated protein and cofilin. Nat Commun, 10, 2019
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4Q57
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![BU of 4q57 by Molmil](/molmil-images/mine/4q57) | Crystal structure of the plectin 1a actin-binding domain/N-terminal domain of calmodulin complex | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | Authors: | Song, J.-G, Kostan, J, Grishkovskaya, I, Djinovic-Carugo, K. | Deposit date: | 2014-04-16 | Release date: | 2014-07-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the plectin 1a actin-binding domain/N-terminal domain of calmodulin complex To be Published
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1S5G
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![BU of 1s5g by Molmil](/molmil-images/mine/1s5g) | Structure of Scallop myosin S1 reveals a novel nucleotide conformation | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, MAGNESIUM ION, ... | Authors: | Risal, D, Gourinath, S, Himmel, D.M, Szent-Gyorgyi, A.G, Cohen, C. | Deposit date: | 2004-01-20 | Release date: | 2004-06-22 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Myosin subfragment 1 structures reveal a partially bound nucleotide and a complex salt bridge that helps couple nucleotide and actin binding. Proc.Natl.Acad.Sci.Usa, 101, 2004
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2QDQ
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![BU of 2qdq by Molmil](/molmil-images/mine/2qdq) | Crystal structure of the talin dimerisation domain | Descriptor: | Talin-1 | Authors: | Gingras, A.R, Putz, N.S.M, Bate, N, Barsukov, I.L, Critchley, D.R.C. | Deposit date: | 2007-06-21 | Release date: | 2008-01-29 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The structure of the C-terminal actin-binding domain of talin. Embo J., 27, 2008
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1YU5
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![BU of 1yu5 by Molmil](/molmil-images/mine/1yu5) | Crystal Structure of the Headpiece Domain of Chicken Villin | Descriptor: | Villin | Authors: | Meng, J, Vardar, D, Wang, Y, Guo, H.C, Head, J.F, McKnight, C.J. | Deposit date: | 2005-02-11 | Release date: | 2005-09-06 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | High-resolution crystal structures of villin headpiece and mutants with reduced f-actin binding activity. Biochemistry, 44, 2005
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1YU8
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![BU of 1yu8 by Molmil](/molmil-images/mine/1yu8) | Crystal Structure of the R37A Mutant of Villin Headpiece | Descriptor: | Villin | Authors: | Meng, J, Vardar, D, Wang, Y, Guo, H.C, Head, J.F, McKnight, C.J. | Deposit date: | 2005-02-12 | Release date: | 2005-09-06 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | High-resolution crystal structures of villin headpiece and mutants with reduced F-actin binding activity. Biochemistry, 44, 2005
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1YU7
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![BU of 1yu7 by Molmil](/molmil-images/mine/1yu7) | Crystal Structure of the W64Y mutant of Villin Headpiece | Descriptor: | Villin | Authors: | Meng, J, Vardar, D, Wang, Y, Guo, H.C, Head, J.F, McKnight, C.J. | Deposit date: | 2005-02-12 | Release date: | 2005-09-06 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | High-resolution crystal structures of villin headpiece and mutants with reduced F-actin binding activity. Biochemistry, 44, 2005
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4Q58
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![BU of 4q58 by Molmil](/molmil-images/mine/4q58) | |
4Q59
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![BU of 4q59 by Molmil](/molmil-images/mine/4q59) | |
1SR6
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![BU of 1sr6 by Molmil](/molmil-images/mine/1sr6) | Structure of nucleotide-free scallop myosin S1 | Descriptor: | CALCIUM ION, MAGNESIUM ION, Myosin essential light chain, ... | Authors: | Risal, D, Gourinath, S, Himmel, D.M, Szent-Gyorgyi, A.G, Cohen, C. | Deposit date: | 2004-03-22 | Release date: | 2004-06-15 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Myosin subfragment 1 structures reveal a partially bound nucleotide and a complex salt bridge that helps couple nucleotide and actin binding. Proc.Natl.Acad.Sci.Usa, 101, 2004
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2X1P
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![BU of 2x1p by Molmil](/molmil-images/mine/2x1p) | Gelsolin Nanobody | Descriptor: | GELSOLIN NANOBODY | Authors: | Van Den Abbeele, A, Declercq, S, De Ganck, A, De Corte, V, Van Loo, B, Srinivasan, V, Steyaert, J, Van De Kerckhove, J, Gettemans, J. | Deposit date: | 2010-01-03 | Release date: | 2011-01-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | A Llama-Derived Gelsolin Single-Domain Antibody Blocks Gelsolin-G-Actin Interaction. Cell.Mol.Life Sci., 67, 2010
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2X1Q
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![BU of 2x1q by Molmil](/molmil-images/mine/2x1q) | Gelsolin Nanobody | Descriptor: | GELSOLIN NANOBODY | Authors: | Van Den Abbeele, A, Declercq, S, De Ganck, A, De Corte, V, Van Loo, B, Srinivasan, V, Steyaert, J, Van De Kerckhove, J, Gettemans, J. | Deposit date: | 2010-01-03 | Release date: | 2011-01-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.06 Å) | Cite: | A Llama-Derived Gelsolin Single-Domain Antibody Blocks Gelsolin-G-Actin Interaction. Cell.Mol.Life Sci., 67, 2010
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2X1O
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![BU of 2x1o by Molmil](/molmil-images/mine/2x1o) | Gelsolin Nanobody | Descriptor: | GELSOLIN NANOBODY | Authors: | Van Den Abbeele, A, Declercq, S, De Ganck, A, De Corte, V, Van Loo, B, Srinivasan, V, Steyaert, J, Van De Kerckhove, J, Gettemans, J. | Deposit date: | 2010-01-03 | Release date: | 2011-01-12 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.34 Å) | Cite: | A Llama-Derived Gelsolin Single-Domain Antibody Blocks Gelsolin-G-Actin Interaction. Cell.Mol.Life Sci., 67, 2010
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