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6OLE
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BU of 6ole by Molmil
Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AP and PE tRNAs
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Li, W, Cate, J.H.D.
Deposit date:2019-04-16
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OKP
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BU of 6okp by Molmil
B41 SOSIP.664 in complex with the silent-face antibody SF12 and V3-targeting antibody 10-1074
Descriptor: 10-1074 Heavy Chain,10-1074 Heavy Chain, 10-1074 Light Chain,10-1074 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Barnes, C.O, Bjorkman, P.J.
Deposit date:2019-04-14
Release date:2019-06-05
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope.
Immunity, 50, 2019
6OLF
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BU of 6olf by Molmil
Human ribosome nascent chain complex (CDH1-RNC) stalled by a drug-like molecule with AA and PE tRNAs
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Li, W, Cate, J.H.D.
Deposit date:2019-04-16
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
8G5Z
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BU of 8g5z by Molmil
mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state)
Descriptor: 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ...
Authors:Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C.
Deposit date:2023-02-14
Release date:2023-04-19
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.64 Å)
Cite:mRNA decoding in human is kinetically and structurally distinct from bacteria.
Nature, 617, 2023
8G6J
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BU of 8g6j by Molmil
mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2)
Descriptor: (3R,6R,9S,12S,15S,18S,20R,24aR)-6-[(2S)-butan-2-yl]-3,12-bis[(1R)-1-hydroxy-2-methylpropyl]-8,9,11,17,18-pentamethyl-15-[(2S)-2-methylbutyl]hexadecahydropyrido[1,2-a][1,4,7,10,13,16,19]heptaazacyclohenicosine-1,4,7,10,13,16,19(21H)-heptone, (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 1,4-DIAMINOBUTANE, ...
Authors:Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C.
Deposit date:2023-02-15
Release date:2023-04-19
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:mRNA decoding in human is kinetically and structurally distinct from bacteria.
Nature, 617, 2023
8G5Y
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BU of 8g5y by Molmil
mRNA decoding in human is kinetically and structurally distinct from bacteria (IC state)
Descriptor: 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ...
Authors:Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C.
Deposit date:2023-02-14
Release date:2023-04-19
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.29 Å)
Cite:mRNA decoding in human is kinetically and structurally distinct from bacteria.
Nature, 617, 2023
8GHU
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BU of 8ghu by Molmil
Methyltransferase RmtC bound to the 30S ribosomal subunit
Descriptor: 16S rRNA, 16S rRNA (guanine(1405)-N(7))-methyltransferase, 30S ribosomal protein S12, ...
Authors:Srinivas, P, Conn, G.L, Dunham, C.M.
Deposit date:2023-03-12
Release date:2023-04-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3 Å)
Cite:30S subunit recognition and G1405 modification by the aminoglycoside-resistance 16S ribosomal RNA methyltransferase RmtC.
Biorxiv, 2023
4OSL
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BU of 4osl by Molmil
Crystal structure of TAL effector reveals the recognition between histidine and guanine
Descriptor: DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*CP*AP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*TP*GP*TP*CP*TP*CP*TP*CP*T)-3'), Hax3, ...
Authors:Deng, D, Wu, J.P, Yan, C.Y, Pan, X.J, Yan, N.
Deposit date:2014-02-13
Release date:2014-05-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.447 Å)
Cite:Revisiting the TALE repeat
Protein Cell, 5, 2014
8G60
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BU of 8g60 by Molmil
mRNA decoding in human is kinetically and structurally distinct from bacteria (CR state)
Descriptor: 1,4-DIAMINOBUTANE, 18S rRNA, 28S rRNA, ...
Authors:Holm, M, Natchiar, K.S, Rundlet, E.J, Myasnikov, A.G, Altman, R.B, Blanchard, S.C.
Deposit date:2023-02-14
Release date:2023-04-19
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.54 Å)
Cite:mRNA decoding in human is kinetically and structurally distinct from bacteria.
Nature, 617, 2023
8FL2
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BU of 8fl2 by Molmil
Human nuclear pre-60S ribosomal subunit (State I1)
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Vanden Broeck, A, Klinge, S.
Deposit date:2022-12-21
Release date:2023-07-12
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (2.67 Å)
Cite:Principles of human pre-60 S biogenesis.
Science, 381, 2023
8FL4
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BU of 8fl4 by Molmil
Human nuclear pre-60S ribosomal subunit (State I3)
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Vanden Broeck, A, Klinge, S.
Deposit date:2022-12-21
Release date:2023-07-12
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (2.89 Å)
Cite:Principles of human pre-60 S biogenesis.
Science, 381, 2023
8FL6
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BU of 8fl6 by Molmil
Human nuclear pre-60S ribosomal subunit (State J1)
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Vanden Broeck, A, Klinge, S.
Deposit date:2022-12-21
Release date:2023-07-12
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (2.62 Å)
Cite:Principles of human pre-60 S biogenesis.
Science, 381, 2023
8FLC
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BU of 8flc by Molmil
Human nuclear pre-60S ribosomal subunit (State K3)
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Vanden Broeck, A, Klinge, S.
Deposit date:2022-12-21
Release date:2023-07-12
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Principles of human pre-60 S biogenesis.
Science, 381, 2023
8FKZ
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BU of 8fkz by Molmil
Human nucleolar pre-60S ribosomal subunit (State G)
Descriptor: 28S rRNA, 5.8S rRNA, 60S ribosomal protein L12, ...
Authors:Vanden Broeck, A, Klinge, S.
Deposit date:2022-12-21
Release date:2023-07-12
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Principles of human pre-60 S biogenesis.
Science, 381, 2023
8FLD
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BU of 8fld by Molmil
Human nuclear pre-60S ribosomal subunit (State L1)
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Vanden Broeck, A, Klinge, S.
Deposit date:2022-12-21
Release date:2023-07-12
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (2.58 Å)
Cite:Principles of human pre-60 S biogenesis.
Science, 381, 2023
8FL7
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BU of 8fl7 by Molmil
Human nuclear pre-60S ribosomal subunit (State J2)
Descriptor: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Vanden Broeck, A, Klinge, S.
Deposit date:2022-12-21
Release date:2023-07-12
Last modified:2023-07-26
Method:ELECTRON MICROSCOPY (2.55 Å)
Cite:Principles of human pre-60 S biogenesis.
Science, 381, 2023
4OSM
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BU of 4osm by Molmil
Crystal structure of the S505H mutant of TAL effector dHax3
Descriptor: DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*TP*AP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*TP*AP*TP*CP*TP*CP*TP*CP*T)-3'), Hax3
Authors:Deng, D, Wu, J.P, Yan, C.Y, Pan, X.J, Yan, N.
Deposit date:2014-02-13
Release date:2014-05-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.454 Å)
Cite:Revisiting the TALE repeat
Protein Cell, 5, 2014
6OM7
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BU of 6om7 by Molmil
Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like small molecule with AA and PE tRNAs
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Li, W, Cate, J.H.D.
Deposit date:2019-04-18
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OY7
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BU of 6oy7 by Molmil
X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter at 7 min
Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*TP*CP*TP*GP*AP*TP*GP*CP*AP*GP*G)-3'), DNA (5'-D(P*CP*CP*TP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*AP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Shin, Y, Murakami, K.S.
Deposit date:2019-05-14
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.04 Å)
Cite:Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase.
Nucleic Acids Res., 48, 2020
6OLZ
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BU of 6olz by Molmil
Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with PP tRNA
Descriptor: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ...
Authors:Li, W, Cate, J.H.D.
Deposit date:2019-04-17
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6BOK
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BU of 6bok by Molmil
E. coli release factor 1 (containing deletion 302-304) bound to the 70S ribosome
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Svidritskiy, E, Korostelev, A.A.
Deposit date:2017-11-20
Release date:2018-05-23
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (3.55 Å)
Cite:Conformational Control of Translation Termination on the 70S Ribosome.
Structure, 26, 2018
6ENU
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BU of 6enu by Molmil
Polyproline-stalled ribosome in the presence of elongation-factor P (EF-P)
Descriptor: 16S ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Huter, P, Arenz, S, Wilson, D.N.
Deposit date:2017-10-06
Release date:2017-11-22
Last modified:2018-01-31
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural Basis for Polyproline-Mediated Ribosome Stalling and Rescue by the Translation Elongation Factor EF-P.
Mol. Cell, 68, 2017
8G4L
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BU of 8g4l by Molmil
Cryo-EM structure of the human cardiac myosin filament
Descriptor: Myosin light chain 3, Myosin regulatory light chain 2, ventricular/cardiac muscle isoform, ...
Authors:Dutta, D, Nguyen, V, Padron, R, Craig, R.
Deposit date:2023-02-10
Release date:2023-11-01
Last modified:2023-12-06
Method:ELECTRON MICROSCOPY (6.4 Å)
Cite:Cryo-EM structure of the human cardiac myosin filament.
Nature, 623, 2023
3UMW
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BU of 3umw by Molmil
Crystal structure of Pim1 kinase in complex with inhibitor (Z)-2-[(1H-indazol-3-yl)methylene]-6-methoxy-7-(piperazin-1-ylmethyl)benzofuran-3(2H)-one
Descriptor: (2Z)-2-(1H-indazol-3-ylmethylidene)-6-methoxy-7-(piperazin-1-ylmethyl)-1-benzofuran-3(2H)-one, GLYCEROL, Proto-oncogene serine/threonine-protein kinase pim-1, ...
Authors:Parker, L.J, Handa, N, Yokoyama, S.
Deposit date:2011-11-14
Release date:2012-10-03
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Rational evolution of a novel type of potent and selective proviral integration site in Moloney murine leukemia virus kinase 1 (PIM1) inhibitor from a screening-hit compound.
J.Med.Chem., 55, 2012
6OVY
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BU of 6ovy by Molmil
X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter variant -1C
Descriptor: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*TP*CP*TP*GP*AP*TP*G)-3'), DNA (5'-D(P*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*CP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ...
Authors:Shin, Y, Murakami, K.S.
Deposit date:2019-05-08
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.999 Å)
Cite:Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase.
Nucleic Acids Res., 48, 2020

223532

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