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4OMP
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BU of 4omp by Molmil
Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant Q128K
Descriptor: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, TRIETHYLENE GLYCOL
Authors:Camara-Artigas, A, Bacarizo, J.
Deposit date:2014-01-27
Release date:2014-12-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation.
Plos One, 9, 2014
4OMM
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BU of 4omm by Molmil
Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant N113S
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Proto-oncogene tyrosine-protein kinase Src, ...
Authors:Camara-Artigas, A, Bacarizo, J.
Deposit date:2014-01-27
Release date:2015-01-28
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The role of Gutamine 128 of the SH3 domain of the c-Src tyrosine kinase in 3D domain swapping and amyloid formation
To be Published
5UL6
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BU of 5ul6 by Molmil
The molecular mechanisms by which NS1 of the 1918 Spanish influenza A virus hijack host protein-protein interactions
Descriptor: Adapter molecule crk, Proline-rich motif of nonstructural protein 1 of influenza a virus
Authors:Shen, Q, Zeng, D, Zhao, B, Li, P, Cho, J.H.
Deposit date:2017-01-24
Release date:2017-08-09
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The Molecular Mechanisms Underlying the Hijack of Host Proteins by the 1918 Spanish Influenza Virus.
ACS Chem. Biol., 12, 2017
4QT7
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BU of 4qt7 by Molmil
Crystal structure of the c-Src SH3 domain in complex with a peptide from the Hepatitis C virus NS5A-protein
Descriptor: NS5A, Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A, Bacarizo, J.
Deposit date:2014-07-07
Release date:2014-12-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure of the c-Src-SH3 domain in complex with a proline-rich motif of NS5A protein from the hepatitis C virus.
J.Struct.Biol., 189, 2015
5VEI
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BU of 5vei by Molmil
Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2
Descriptor: Sorbin and SH3 domain-containing protein 2, UNKNOWN ATOM OR ION
Authors:Liu, Y, Tempel, W, Huang, H, Gu, J, Liu, K, Sidhu, S.S, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2017-04-04
Release date:2017-08-02
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Crystal structure of the SH3 domain of human sorbin and SH3 domain-containing protein 2
To be Published
5NP3
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BU of 5np3 by Molmil
Abl2 SH3
Descriptor: Abelson tyrosine-protein kinase 2
Authors:Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L.
Deposit date:2017-04-13
Release date:2018-05-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions.
J.Biol.Chem., 294, 2019
5NP5
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BU of 5np5 by Molmil
Abl2 SH3 pTyr116/161
Descriptor: Abelson tyrosine-protein kinase 2, SULFATE ION
Authors:Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L.
Deposit date:2017-04-13
Release date:2018-05-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions.
J.Biol.Chem., 294, 2019
5NP2
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BU of 5np2 by Molmil
Abl1 SH3 pTyr89/134
Descriptor: Tyrosine-protein kinase ABL1
Authors:Mero, B, Radnai, L, Gogl, G, Leveles, I, Buday, L.
Deposit date:2017-04-13
Release date:2018-05-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions.
J.Biol.Chem., 294, 2019
5O2P
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BU of 5o2p by Molmil
p130Cas SH3 domain PTP-PEST peptide chimera
Descriptor: Breast cancer anti-estrogen resistance 1,Tyrosine-protein phosphatase non-receptor type 12
Authors:Hexnerova, R, Veverka, V.
Deposit date:2017-05-22
Release date:2017-09-20
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners.
Sci Rep, 7, 2017
5OAZ
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BU of 5oaz by Molmil
Crystal structure of the Abl-SH3 domain at pH 7.5
Descriptor: DI(HYDROXYETHYL)ETHER, Tyrosine-protein kinase ABL1
Authors:Camara-Artigas, A.
Deposit date:2017-06-25
Release date:2017-07-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.03 Å)
Cite:Crystal structure of the Abl-SH3 domain at pH 7.5
to be published
5O2M
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BU of 5o2m by Molmil
p130Cas SH3 domain
Descriptor: Breast cancer anti-estrogen resistance 1
Authors:Hexnerova, R, Veverka, V.
Deposit date:2017-05-22
Release date:2017-09-20
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners.
Sci Rep, 7, 2017
5OB0
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BU of 5ob0 by Molmil
Crystal structure of the c-Src-SH3 domain Q128E mutant in complex with the high affinity peptide APP12
Descriptor: APP12, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION
Authors:Camara-Artigas, A.
Deposit date:2017-06-25
Release date:2017-07-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.172 Å)
Cite:Crystal structure of the c-Src-SH3 domain Q128E mutant in complex with the high affinity peptide APP12
to be published
5OB2
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BU of 5ob2 by Molmil
Crystal structure of the c-Src-SH3 domain E97T mutant in complex with the high affinity peptide APP12
Descriptor: APP12, Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A.
Deposit date:2017-06-25
Release date:2017-07-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the c-Src-SH3 domain E97T mutant in complex with the high affinity peptide APP12
to be published
5OAV
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BU of 5oav by Molmil
High resolution crystal structure of the c-Src-SH3 domain mutant E93V in complex with the high affinity synthetic peptide APP12: monoclinic crystal
Descriptor: APP12, Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A.
Deposit date:2017-06-23
Release date:2017-07-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:High resolution crystal structure of the c-Src-SH3 domain mutant E93V in complex with the high affinity synthetic peptide APP12: monoclinic crystal
to be published
5OB1
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BU of 5ob1 by Molmil
Crystal structure of the c-Src-SH3 domain Q128R mutant in complex with the high affinity peptide APP12
Descriptor: APP12, Proto-oncogene tyrosine-protein kinase Src
Authors:Camara-Artigas, A.
Deposit date:2017-06-25
Release date:2017-07-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.172 Å)
Cite:Crystal structure of the c-Src-SH3 domain Q128R mutant in complex with the high affinity peptide APP12
to be published
5O2Q
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BU of 5o2q by Molmil
p130Cas SH3 domain Vinculin peptide chimera
Descriptor: Breast cancer anti-estrogen resistance 1,Vinculin
Authors:Hexnerova, R, Veverka, V.
Deposit date:2017-05-22
Release date:2017-09-20
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural characterization of CAS SH3 domain selectivity and regulation reveals new CAS interaction partners.
Sci Rep, 7, 2017
3C0C
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BU of 3c0c by Molmil
X-ray Crystal Structure of the Rat Endophilin A2 SH3 Domain
Descriptor: Endophilin-A2
Authors:Loll, P.J, Swain, E.
Deposit date:2008-01-19
Release date:2008-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of the SH3 domain of rat endophilin A2
To be Published
3CQT
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BU of 3cqt by Molmil
N53I V55L MUTANT of FYN SH3 DOMAIN
Descriptor: Proto-oncogene tyrosine-protein kinase Fyn
Authors:Neculai, A.M, Zarrine-Afsar, A, Howell, P.L, Davidson, A, Chan, H.S.
Deposit date:2008-04-03
Release date:2008-07-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Theoretical and experimental demonstration of the importance of specific nonnative interactions in protein folding.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3EG2
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BU of 3eg2 by Molmil
Crystal structure of the N114Q mutant of ABL-SH3 domain
Descriptor: GLYCEROL, Proto-oncogene tyrosine-protein kinase ABL1
Authors:Camara-Artigas, A.
Deposit date:2008-09-10
Release date:2009-09-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Role of interfacial water molecules in proline-rich ligand recognition by the Src homology 3 domain of Abl.
J.Biol.Chem., 285, 2010
3EG1
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BU of 3eg1 by Molmil
Crystal structure of the N114Q mutant of ABL-SH3 domain complexed with a designed high-affinity peptide ligand: implications for SH3-ligand interactions
Descriptor: Proto-oncogene tyrosine-protein kinase ABL1, SULFATE ION, p41 peptide
Authors:Camara-Artigas, A.
Deposit date:2008-09-10
Release date:2009-09-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Role of interfacial water molecules in proline-rich ligand recognition by the Src homology 3 domain of Abl.
J.Biol.Chem., 285, 2010
3EGU
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BU of 3egu by Molmil
Crystal structure of the N114A mutant of ABL-SH3 domain
Descriptor: GLYCEROL, Proto-oncogene tyrosine-protein kinase ABL1, SULFATE ION
Authors:Camara-Artigas, A.
Deposit date:2008-09-11
Release date:2009-09-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Role of interfacial water molecules in proline-rich ligand recognition by the Src homology 3 domain of Abl.
J.Biol.Chem., 285, 2010
3EG3
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BU of 3eg3 by Molmil
Crystal structure of the N114A mutant of ABL-SH3 domain
Descriptor: GLYCEROL, Proto-oncogene tyrosine-protein kinase ABL1
Authors:Camara-Artigas, A.
Deposit date:2008-09-10
Release date:2009-09-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Role of interfacial water molecules in proline-rich ligand recognition by the Src homology 3 domain of Abl.
J.Biol.Chem., 285, 2010
3EG0
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BU of 3eg0 by Molmil
Crystal structure of the N114T mutant of ABL-SH3 domain
Descriptor: GLYCEROL, Proto-oncogene tyrosine-protein kinase ABL1
Authors:Camara-Artigas, A.
Deposit date:2008-09-10
Release date:2009-09-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Role of interfacial water molecules in proline-rich ligand recognition by the Src homology 3 domain of Abl.
J.Biol.Chem., 285, 2010
3FJ5
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BU of 3fj5 by Molmil
Crystal structure of the c-src-SH3 domain
Descriptor: ACETATE ION, GLYCEROL, Proto-oncogene tyrosine-protein kinase Src, ...
Authors:Camara-Artigas, A.
Deposit date:2008-12-14
Release date:2009-03-03
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Intertwined dimeric structure for the SH3 domain of the c-Src tyrosine kinase induced by polyethylene glycol binding
Febs Lett., 583, 2009
3GBQ
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BU of 3gbq by Molmil
SOLUTION NMR STRUCTURE OF THE GRB2 N-TERMINAL SH3 DOMAIN COMPLEXED WITH A TEN-RESIDUE PEPTIDE DERIVED FROM SOS DIRECT REFINEMENT AGAINST NOES, J-COUPLINGS, AND 1H AND 13C CHEMICAL SHIFTS, MINIMIZED AVERAGE STRUCTURE
Descriptor: GRB2, SOS-1
Authors:Wittekind, M, Mapelli, C, Lee, V, Goldfarb, V, Friedrichs, M.S, Meyers, C.A, Mueller, L.
Deposit date:1996-12-23
Release date:1997-09-04
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Solution structure of the Grb2 N-terminal SH3 domain complexed with a ten-residue peptide derived from SOS: direct refinement against NOEs, J-couplings and 1H and 13C chemical shifts.
J.Mol.Biol., 267, 1997

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