5VKL
 
 | | SPT6 tSH2-RPB1 1476-1500 pS1493 | | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, Transcription elongation factor SPT6 | | Authors: | Sdano, M.A, Whitby, F.G, Hill, C.P. | | Deposit date: | 2017-04-21 | | Release date: | 2017-10-25 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.198 Å) | | Cite: | A novel SH2 recognition mechanism recruits Spt6 to the doubly phosphorylated RNA polymerase II linker at sites of transcription.
Elife, 6, 2017
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6YHZ
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6YI2
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5VKO
 | | SPT6 tSH2-RPB1 1468-1500 pT1471, pS1493 | | Descriptor: | DNA-directed RNA polymerase II subunit RPB1, ISOPROPYL ALCOHOL, Transcription elongation factor SPT6 | | Authors: | Sdano, M.A, Whitby, F.G, Hill, C.P. | | Deposit date: | 2017-04-21 | | Release date: | 2017-09-20 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | A novel SH2 recognition mechanism recruits Spt6 to the doubly phosphorylated RNA polymerase II linker at sites of transcription.
Elife, 6, 2017
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4QJF
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1KU7
 | | Crystal Structure of Thermus aquatics RNA Polymerase SigmaA Subunit Region 4 Bound to-35 Element DNA | | Descriptor: | 5'-D(*CP*CP*TP*TP*GP*AP*CP*AP*AP*AP*G)-3', 5'-D(*CP*CP*TP*TP*TP*GP*TP*CP*AP*AP*G)-3', sigma factor sigA | | Authors: | Campbell, E.A, Muzzin, O, Chlenov, M, Sun, J.L, Olson, C.A, Weinman, O, Trester-Zedlitz, M.L, Darst, S.A. | | Deposit date: | 2002-01-21 | | Release date: | 2002-03-29 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of the bacterial RNA polymerase promoter specificity sigma subunit.
Mol.Cell, 9, 2002
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1KU3
 | | Crystal Structure of Thermus aquaticus RNA Polymerase Sigma Subunit Fragment, Region 4 | | Descriptor: | sigma factor sigA | | Authors: | Campbell, E.A, Muzzin, O, Chlenov, M, Sun, J.L, Olson, C.A, Weinman, O, Trester-Zedlitz, M.L, Darst, S.A. | | Deposit date: | 2002-01-21 | | Release date: | 2002-04-03 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure of the bacterial RNA polymerase promoter specificity sigma subunit.
Mol.Cell, 9, 2002
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1KU2
 | | Crystal Structure of Thermus aquaticus RNA Polymerase Sigma Subunit Fragment Containing Regions 1.2 to 3.1 | | Descriptor: | SULFATE ION, sigma factor sigA | | Authors: | Campbell, E.A, Muzzin, O, Chlenov, M, Sun, J.L, Olson, C.A, Weinman, O, Trester-Zedlitz, M.L, Darst, S.A. | | Deposit date: | 2002-01-21 | | Release date: | 2002-04-03 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structure of the bacterial RNA polymerase promoter specificity sigma subunit.
Mol.Cell, 9, 2002
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2J7W
 | | Dengue virus NS5 RNA dependent RNA polymerase domain complexed with 3' dGTP | | Descriptor: | DI(HYDROXYETHYL)ETHER, GUANOSINE-5'-TRIPHOSPHATE, POLYPROTEIN, ... | | Authors: | Yap, T.L, Xu, T, Chen, Y.L, Malet, H, Egloff, M.P, Canard, B, Vasudevan, S.G, Lescar, J. | | Deposit date: | 2006-10-17 | | Release date: | 2007-03-13 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal Structure of the Dengue Virus RNA- Dependent RNA Polymerase Catalytic Domain at 1.85 Angstrom Resolution.
J.Virol., 81, 2007
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2L0I
 | | Solution structure of Rtt103 CTD-interacting domain bound to a Ser2 phosphorylated CTD peptide | | Descriptor: | DNA-directed RNA polymerase, Regulator of Ty1 transposition protein 103 | | Authors: | Lunde, B.M, Reichow, S.L, Kim, M, Suh, H, Leeper, T.C, Yang, F, Mutschler, H, Buratowski, S, Meinhart, A, Varani, G. | | Deposit date: | 2010-07-06 | | Release date: | 2010-09-08 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Cooperative interaction of transcription termination factors with the RNA polymerase II C-terminal domain.
Nat.Struct.Mol.Biol., 17, 2010
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2YU3
 | | Solution structure of the domain swapped WingedHelix in DNA-directed RNA polymerase III 39 kDa polypeptide | | Descriptor: | DNA-directed RNA polymerase III 39 kDa polypeptide F variant | | Authors: | He, F, Muto, Y, Inoue, M, Kigawa, T, Shirouzu, M, Terada, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2007-04-05 | | Release date: | 2007-10-09 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the domain swapped WingedHelix in DNA-directed RNA polymerase III 39 kDa polypeptide
To be Published
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2F88
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1Z31
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2KRC
 | | Solution structure of the N-terminal domain of Bacillus subtilis delta subunit of RNA polymerase | | Descriptor: | DNA-directed RNA polymerase subunit delta | | Authors: | Motackova, V, Sanderova, H, Zidek, L, Novacek, J, Padrta, P, Svenkova, A, Jonak, J, Krasny, L, Sklenar, V. | | Deposit date: | 2009-12-16 | | Release date: | 2010-04-07 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the N-terminal domain of Bacillus subtilis delta subunit of RNA polymerase and its classification based on structural homologs
Proteins, 78, 2010
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3PJP
 | | A Tandem SH2 Domain in Transcription Elongation Factor Spt6 Binds the Phosphorylated RNA Polymerase II C-terminal Repeat Domain(CTD) | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, Transcription elongation factor SPT6 | | Authors: | Sun, M, Lariviere, L, Dengl, S, Mayer, A, Cramer, P. | | Deposit date: | 2010-11-10 | | Release date: | 2010-11-24 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | A tandem SH2 domain in transcription elongation factor Spt6 binds the phosphorylated RNA polymerase II C-terminal repeat domain (CTD).
J.Biol.Chem., 285, 2010
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2IJD
 | | Crystal Structure of the Poliovirus Precursor Protein 3CD | | Descriptor: | Picornain 3C, RNA-directed RNA polymerase, SULFATE ION, ... | | Authors: | Marcotte, L.L, Gohara, D.W, Filman, D.J, Hogle, J.M. | | Deposit date: | 2006-09-29 | | Release date: | 2007-02-13 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Crystal structure of poliovirus 3CD: virally-encoded protease and precursor to the RNA-dependent RNA polymerase.
J.Virol., 81, 2007
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7ZPM
 | | Influenza A/H7N9 polymerase apo-protein dimer complex | | Descriptor: | Polymerase acidic protein, Polymerase basic protein 2, RNA-directed RNA polymerase catalytic subunit | | Authors: | Cusack, S, Kouba, T. | | Deposit date: | 2022-04-27 | | Release date: | 2022-12-28 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (2.81 Å) | | Cite: | Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106.
Cell Rep, 42, 2023
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7NKY
 | | RNA Polymerase II-Spt4/5-nucleosome-FACT structure | | Descriptor: | Chromatin elongation factor SPT4, DNA (138-MER), DNA (148-MER), ... | | Authors: | Farnung, L, Ochmann, M, Engeholm, M, Cramer, P. | | Deposit date: | 2021-02-19 | | Release date: | 2021-07-07 | | Last modified: | 2024-07-10 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structural basis of nucleosome transcription mediated by Chd1 and FACT.
Nat.Struct.Mol.Biol., 28, 2021
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4ZPB
 | | Coxsackievirus B3 Polymerase - F364W mutant | | Descriptor: | RNA-directed RNA polymerase | | Authors: | Peersen, O.B, McDonald, S.M. | | Deposit date: | 2015-05-07 | | Release date: | 2016-05-11 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.797 Å) | | Cite: | Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo.
J.Biol.Chem., 291, 2016
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4ZPD
 | | Coxsackievirus B3 Polymerase - A345V mutant | | Descriptor: | RNA-directed RNA polymerase | | Authors: | Peersen, O.B, McDonald, S.M. | | Deposit date: | 2015-05-07 | | Release date: | 2016-05-11 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.797 Å) | | Cite: | Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo.
J.Biol.Chem., 291, 2016
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4ZP8
 | | Coxsackievirus B3 Polymerase - F364L mutant | | Descriptor: | RNA-dependent RNA polymerase | | Authors: | Peersen, O.B, McDonald, S.M. | | Deposit date: | 2015-05-07 | | Release date: | 2016-05-11 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.894 Å) | | Cite: | Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo.
J.Biol.Chem., 291, 2016
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4ZP9
 | | Coxsackievirus B3 Polymerase - F364I mutant | | Descriptor: | RNA-dependent RNA polymerase | | Authors: | Peersen, O.B, McDonald, S.M. | | Deposit date: | 2015-05-07 | | Release date: | 2016-05-11 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.799 Å) | | Cite: | Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo.
J.Biol.Chem., 291, 2016
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4ZPA
 | | Coxsackievirus B3 Polymerase - F364Y mutant | | Descriptor: | RNA-directed RNA polymerase, SULFATE ION | | Authors: | Peersen, O.B, McDonald, S.M. | | Deposit date: | 2015-05-07 | | Release date: | 2016-05-11 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.665 Å) | | Cite: | Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo.
J.Biol.Chem., 291, 2016
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4ZPC
 | | Coxsackievirus B3 Polymerase - A341G mutant | | Descriptor: | RNA-dependent RNA polymerase | | Authors: | Peersen, O.B, McDonald, S.M. | | Deposit date: | 2015-05-07 | | Release date: | 2016-05-11 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.59 Å) | | Cite: | Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo.
J.Biol.Chem., 291, 2016
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5CCV
 | | Crystal structure of full-length NS5 from dengue virus type 3 | | Descriptor: | RNA-directed RNA polymerase NS5, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION | | Authors: | Klema, V.J, Choi, K.H. | | Deposit date: | 2015-07-02 | | Release date: | 2016-02-03 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Dengue Virus Nonstructural Protein 5 (NS5) Assembles into a Dimer with a Unique Methyltransferase and Polymerase Interface.
Plos Pathog., 12, 2016
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