PDB: 13488 resultsInfo pagesStatus searchChemie searchBIRD

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3MSH	Crystal structure of Hepatitis B X-Interacting Protein at high resolution Descriptor: GLYCEROL, Hepatitis B virus X-interacting protein, ISOPROPYL ALCOHOL, ... Authors: Garcia-Saez, I, Skoufias, D. Deposit date: 2010-04-29 Release date: 2010-11-10 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.51 Å) Cite: Structural Characterization of HBXIP: The Protein That Interacts with the Anti-Apoptotic Protein Survivin and the Oncogenic Viral Protein HBx. J.Mol.Biol., 405, 2011
7AW9	CCAAT-binding complex and HapX bound to Aspergillus fumigatus cccA DNA Descriptor: BZIP domain-containing protein, CBFD_NFYB_HMF domain-containing protein, CHLORIDE ION, ... Authors: Huber, E.M, Groll, M. Deposit date: 2020-11-06 Release date: 2022-04-13 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Structural insights into cooperative DNA recognition by the CCAAT-binding complex and its bZIP transcription factor HapX. Structure, 30, 2022
7AW7	CCAAT-binding complex and HapX bound to Aspergillus nidulans cccA DNA Descriptor: BZIP domain-containing protein, CBFD_NFYB_HMF domain-containing protein, CHLORIDE ION, ... Authors: Huber, E.M, Groll, M. Deposit date: 2020-11-06 Release date: 2022-04-13 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Structural insights into cooperative DNA recognition by the CCAAT-binding complex and its bZIP transcription factor HapX. Structure, 30, 2022
3MSV	The hypoxic regulator of sterol synthesis Nro1 is a nuclear import adaptor Descriptor: Nuclear import adaptor, Nro1 Authors: Yeh, T.L, Amzel, L.M, Bianchet, M.A. Deposit date: 2010-04-29 Release date: 2011-04-20 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.18 Å) Cite: The hypoxic regulator of sterol synthesis nro1 is a nuclear import adaptor. Structure, 19, 2011
7EL2	Crystal structure of apo-HpaR from Acinetobacter baumannii Descriptor: Homoprotocatechuate degradation operon regulator HpaR Authors: Permsirivisarn, P, Pakotiprapha, D. Deposit date: 2021-04-07 Release date: 2022-01-19 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Mechanism of transcription regulation by Acinetobacter baumannii HpaR in the catabolism of p-hydroxyphenylacetate. Febs J., 289, 2022
7EL3	Crystal structure of HpaR-DNA complex from Acinetobacter baumannii Descriptor: Chains: C, Chains: D, GLYCEROL, ... Authors: Permsirivisarn, P, Pakotiprapha, D. Deposit date: 2021-04-07 Release date: 2022-01-19 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Mechanism of transcription regulation by Acinetobacter baumannii HpaR in the catabolism of p-hydroxyphenylacetate. Febs J., 289, 2022
3MZ6	Crystal structure of D101L Fe2+ HDAC8 complexed with M344 Descriptor: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, FE (II) ION, Histone deacetylase 8, ... Authors: Dowling, D.P, Gattis, S.G, Fierke, C.A, Christianson, D.W. Deposit date: 2010-05-11 Release date: 2010-06-23 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2 Å) Cite: Structures of metal-substituted human histone deacetylase 8 provide mechanistic inferences on biological function. Biochemistry, 49, 2010
3MZ7	Crystal structure of D101L Co2+ HDAC8 complexed with M344 Descriptor: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, COBALT (II) ION, GLYCEROL, ... Authors: Dowling, D.P, Gattis, S.G, Fierke, C.A, Christianson, D.W. Deposit date: 2010-05-11 Release date: 2010-06-23 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structures of metal-substituted human histone deacetylase 8 provide mechanistic inferences on biological function. Biochemistry, 49, 2010
2K2F	Solution structure of Ca2+-S100A1-RyRP12 Descriptor: CALCIUM ION, Protein S100-A1, Ryanodine receptor 1 peptide Authors: Wright, N.T, Varney, K.M, Weber, D.J. Deposit date: 2008-04-01 Release date: 2008-07-29 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: S100A1 and Calmodulin Compete for the Same Binding Site on Ryanodine Receptor. J.Biol.Chem., 283, 2008
3MZ3	Crystal structure of Co2+ HDAC8 complexed with M344 Descriptor: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, COBALT (II) ION, Histone deacetylase 8, ... Authors: Dowling, D.P, Gattis, S.G, Fierke, C.A, Christianson, D.W. Deposit date: 2010-05-11 Release date: 2010-06-23 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Structures of metal-substituted human histone deacetylase 8 provide mechanistic inferences on biological function. Biochemistry, 49, 2010
3MZ4	Crystal structure of D101L Mn2+ HDAC8 complexed with M344 Descriptor: 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, GLYCEROL, Histone deacetylase 8, ... Authors: Dowling, D.P, Gattis, S.G, Fierke, C.A, Christianson, D.W. Deposit date: 2010-05-11 Release date: 2010-06-23 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.845 Å) Cite: Structures of metal-substituted human histone deacetylase 8 provide mechanistic inferences on biological function. Biochemistry, 49, 2010
5WS1	Structure of human PARP1 catalytic domain bound to a benzoimidazole inhibitor Descriptor: 2-[(3R)-3-azanylpyrrolidin-1-yl]carbonyl-1H-benzimidazole-4-carboxamide, Poly [ADP-ribose] polymerase 1 Authors: Cao, R, Wang, Y.L, Zhou, J, Huang, N, Xu, B.L. Deposit date: 2016-12-04 Release date: 2017-01-25 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structure of human PARP1 catalytic domain bound to a benzoimidazole inhibitor To Be Published
7BA7	Cys-42-tethered stabilizer 9 of 14-3-3(sigma)/ERa PPI Descriptor: 14-3-3 protein sigma, 2-[3,5-bis(chloranyl)phenoxy]-2-methyl-~{N}-(2-sulfanylethyl)propanamide, Estrogen receptor, ... Authors: Sijbesma, E, Ottmann, C. Deposit date: 2020-12-15 Release date: 2021-07-07 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers. Acs Med.Chem.Lett., 12, 2021
7BA5	Cys-42-tethered stabilizer 7 of 14-3-3(sigma)/ERa PPI Descriptor: 14-3-3 protein sigma, 2-(4-fluoranylphenoxy)-2-methyl-~{N}-(2-sulfanylethyl)propanamide, Estrogen receptor, ... Authors: Sijbesma, E, Ottmann, C. Deposit date: 2020-12-15 Release date: 2021-07-07 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers. Acs Med.Chem.Lett., 12, 2021
7BA9	Cys-42-tethered stabilizer 11 of 14-3-3(sigma)/ERa PPI Descriptor: 14-3-3 protein sigma, 2-methyl-2-(4-methylphenoxy)-~{N}-(2-sulfanylethyl)propanamide, Estrogen receptor, ... Authors: Sijbesma, E, Ottmann, C. Deposit date: 2020-12-15 Release date: 2021-07-07 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.48 Å) Cite: Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers. Acs Med.Chem.Lett., 12, 2021
7BAA	Cys-42-tethered stabilizer 12 of 14-3-3(sigma)/ERa PPI Descriptor: 14-3-3 protein sigma, 2-(4-bromanyl-3-methoxy-phenoxy)-2-methyl-~{N}-(2-sulfanylethyl)propanamide, Estrogen receptor, ... Authors: Sijbesma, E, Ottmann, C. Deposit date: 2020-12-15 Release date: 2021-07-07 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.1 Å) Cite: Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers. Acs Med.Chem.Lett., 12, 2021
7BA8	Cys-42-tethered stabilizer 10 of 14-3-3(sigma)/ERa PPI Descriptor: 14-3-3 protein sigma, 2-methyl-2-phenoxy-~{N}-(2-sulfanylethyl)propanamide, Estrogen receptor, ... Authors: Sijbesma, E, Ottmann, C. Deposit date: 2020-12-15 Release date: 2021-07-07 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.2 Å) Cite: Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers. Acs Med.Chem.Lett., 12, 2021
7B9T	Cys-45-tethered stabilizer 5 of 14-3-3(sigma)/ERa PPI Descriptor: 14-3-3 protein sigma, 2-(4-chlorophenyl)sulfanyl-~{N}-(3-sulfanylpropyl)ethanamide, Estrogen receptor, ... Authors: Sijbesma, E, Ottmann, C. Deposit date: 2020-12-14 Release date: 2021-07-07 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (1.15 Å) Cite: Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers. Acs Med.Chem.Lett., 12, 2021
7BA6	Cys-42-tethered stabilizer 8 of 14-3-3(sigma)/ERa PPI Descriptor: 14-3-3 protein sigma, 2-[3,5-bis(fluoranyl)phenoxy]-2-methyl-~{N}-(2-sulfanylethyl)propanamide, Estrogen receptor, ... Authors: Sijbesma, E, Ottmann, C. Deposit date: 2020-12-15 Release date: 2021-07-07 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers. Acs Med.Chem.Lett., 12, 2021
7BAB	Cys-42-tethered stabilizer 13 of 14-3-3(sigma)/ERa PPI Descriptor: 14-3-3 protein sigma, 2-[2-chloranyl-4-[oxidanyl(oxidanylidene)-$l^{4}-azanyl]phenoxy]-2-methyl-~{N}-(2-sulfanylethyl)propanamide, Estrogen receptor, ... Authors: Sijbesma, E, Ottmann, C. Deposit date: 2020-12-15 Release date: 2021-07-07 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers. Acs Med.Chem.Lett., 12, 2021
7B9M	Cys-45-tethered stabilizer 3 of 14-3-3(sigma)/ERa PPI Descriptor: 14-3-3 protein sigma, 2-(2-cyanophenyl)sulfanyl-~{N}-(2-sulfanylethyl)benzamide, Estrogen receptor, ... Authors: Sijbesma, E, Ottmann, C. Deposit date: 2020-12-14 Release date: 2021-07-07 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers. Acs Med.Chem.Lett., 12, 2021
7B9R	Cys-45-tethered stabilizer 4 of 14-3-3(sigma)/ERa PPI Descriptor: 14-3-3 protein sigma, 2-(2-cyanophenyl)sulfanyl-~{N}-(3-sulfanylpropyl)benzamide, Estrogen receptor, ... Authors: Sijbesma, E, Ottmann, C. Deposit date: 2020-12-14 Release date: 2021-07-07 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.15 Å) Cite: Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers. Acs Med.Chem.Lett., 12, 2021
7BA3	Cys-42-tethered stabilizer 6 of 14-3-3(sigma)/ERa PPI Descriptor: 14-3-3 protein sigma, 2-(4-bromanylphenoxy)-2-methyl-~{N}-(2-sulfanylethyl)propanamide, Estrogen receptor, ... Authors: Sijbesma, E, Ottmann, C. Deposit date: 2020-12-15 Release date: 2021-07-07 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Exploration of a 14-3-3 PPI Pocket by Covalent Fragments as Stabilizers. Acs Med.Chem.Lett., 12, 2021
5WRQ	Structure of human PARP1 catalytic domain bound to a quinazoline-2,4(1H,3H)-dione inhibitor Descriptor: 5-[[2,4-bis(oxidanylidene)quinazolin-1-yl]methyl]-2-fluoranyl-N-[(3R)-1-(3-methylbutyl)pyrrolidin-3-yl]benzamide, Poly [ADP-ribose] polymerase 1 Authors: Cao, R, Wang, Y.L, Zhou, J, Huang, N, Xu, B.L. Deposit date: 2016-12-03 Release date: 2017-01-25 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Structure of human PARP1 catalytic domain bound to a quinazoline-2,4(1H,3H)-dione inhibitor To Be Published
5WS0	Structure of human PARP1 catalytic domain bound to a benzoimidazole inhibitor Descriptor: 2-piperazin-1-ylcarbonyl-1H-benzimidazole-4-carboxamide, Poly [ADP-ribose] polymerase 1 Authors: Cao, R, Wang, Y.L, Zhou, J, Huang, N, Xu, B.L. Deposit date: 2016-12-04 Release date: 2017-01-25 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structure of human PARP1 catalytic domain bound to a benzoimidazole inhibitor To Be Published

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