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7Y8A
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BU of 7y8a by Molmil
Cryo-EM structure of cryptophyte photosystem I
Descriptor: (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E})-3,7,12,16-tetramethyl-18-[(4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-3,5,7,9,11,13,15-heptaen-1,17-diynyl]cyclohex-3-en-1-ol, (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohexen-1-yl)octadeca-3,5,7,9,11,13,15,17-octaen-1-ynyl]cyclohex-3-en-1-ol, (1~{R})-3,5,5-trimethyl-4-[(3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(1~{R},4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohex-2-en-1-yl]octadeca-3,5,7,9,11,13,15,17-octaen-1-ynyl]cyclohex-3-en-1-ol, ...
Authors:Zhao, L.S, Zhang, Y.Z, Liu, L.N, Li, K.
Deposit date:2022-06-23
Release date:2023-04-12
Last modified:2023-07-12
Method:ELECTRON MICROSCOPY (2.71 Å)
Cite:Structural basis and evolution of the photosystem I-light-harvesting supercomplex of cryptophyte algae.
Plant Cell, 35, 2023
4EI4
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BU of 4ei4 by Molmil
JAK1 kinase (JH1 domain) in complex with compound 20
Descriptor: (1R,3R)-3-(2-methylimidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(8H)-yl)cyclohexanol, Tyrosine-protein kinase JAK1
Authors:Eigenbrot, C, Steffek, M.
Deposit date:2012-04-04
Release date:2012-07-04
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Discovery and optimization of C-2 methyl imidazopyrrolopyridines as potent and orally bioavailable JAK1 inhibitors with selectivity over JAK2.
J.Med.Chem., 55, 2012
7XRZ
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BU of 7xrz by Molmil
Crystal structure of BRIL and SRP2070_Fab complex
Descriptor: IGG HEAVY CHAIN, IGG LIGHT CHAIN, Soluble cytochrome b562
Authors:Suzuki, M, Miyagi, H, Yasunaga, M, Asada, H, Iwata, S, Saito, J.
Deposit date:2022-05-12
Release date:2023-05-10
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural insight into an anti-BRIL Fab as a G-protein-coupled receptor crystallization chaperone.
Acta Crystallogr D Struct Biol, 79, 2023
3KK9
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BU of 3kk9 by Molmil
CaMKII Substrate Complex B
Descriptor: Calcium/calmodulin dependent protein kinase II
Authors:Kuriyan, J, Chao, L.H, Pellicena, P, Deindl, S, Barclay, L.A, Schulman, H.
Deposit date:2009-11-04
Release date:2010-02-09
Last modified:2021-10-13
Method:X-RAY DIFFRACTION (3.206 Å)
Cite:Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation.
Nat.Struct.Mol.Biol., 17, 2010
4IW2
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BU of 4iw2 by Molmil
HSA-glucose complex
Descriptor: D-glucose, PHOSPHATE ION, Serum albumin, ...
Authors:Wang, Y, Yu, H, Shi, X, Luo, Z, Huang, M.
Deposit date:2013-01-23
Release date:2013-04-24
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Structural mechanism of ring-opening reaction of glucose by human serum albumin
J.Biol.Chem., 288, 2013
4O98
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BU of 4o98 by Molmil
Crystal structure of Pseudomonas oleovorans PoOPH mutant H250I/I263W
Descriptor: ZINC ION, organophosphorus hydrolase
Authors:Luo, X.J, Kong, X.D, Zhao, J, Chen, Q, Zhou, J.H, Xu, J.H.
Deposit date:2014-01-02
Release date:2014-12-03
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.251 Å)
Cite:Switching a newly discovered lactonase into an efficient and thermostable phosphotriesterase by simple double mutations His250Ile/Ile263Trp
Biotechnol.Bioeng., 111, 2014
4F09
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BU of 4f09 by Molmil
Discovery and Optimization of C-2 Methyl Imidazo-pyrrolopyridines as Potent and Orally Bioavailable JAK1 Inhibitors with Selectivity over JAK2
Descriptor: 2-methyl-1-(piperidin-4-yl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine, Tyrosine-protein kinase JAK2
Authors:Murray, J.M.
Deposit date:2012-05-03
Release date:2012-07-04
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Discovery and Optimization of C-2 Methyl Imidazopyrrolopyridines as Potent and Orally Bioavailable JAK1 Inhibitors with Selectivity over JAK2.
J.Med.Chem., 55, 2012
7Y9I
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BU of 7y9i by Molmil
Complex structure of AtYchF1 with ppGpp
Descriptor: GUANOSINE-5',3'-TETRAPHOSPHATE, MAGNESIUM ION, Obg-like ATPase 1
Authors:Li, X, Chen, Z.
Deposit date:2022-06-24
Release date:2023-07-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Co-crystalization reveals the interaction between AtYchF1 and ppGpp.
Front Mol Biosci, 9, 2022
4ITQ
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BU of 4itq by Molmil
Crystal structure of hypothetical protein SCO1480 bound to DNA
Descriptor: 5'-D(P*CP*CP*GP*CP*GP*CP*GP*C)-3', 5'-D(P*GP*CP*GP*CP*GP*CP*GP*G)-3', Putative uncharacterized protein SCO1480
Authors:Guarne, A, Nanji, T, Gloyd, M, Swiercz, J.P, Elliot, M.A.
Deposit date:2013-01-18
Release date:2013-03-27
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A novel nucleoid-associated protein specific to the actinobacteria.
Nucleic Acids Res., 41, 2013
1NRP
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BU of 1nrp by Molmil
CRYSTALLOGRAPHIC STRUCTURES OF THROMBIN COMPLEXED WITH THROMBIN RECEPTOR PEPTIDES: EXISTENCE OF EXPECTED AND NOVEL BINDING MODES
Descriptor: ALPHA-THROMBIN (LARGE SUBUNIT), ALPHA-THROMBIN (SMALL SUBUNIT), RECEPTOR BASED PEPTIDE NR'S
Authors:Tulinsky, A, Mathews, I.I.
Deposit date:1994-01-18
Release date:1994-05-31
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes.
Biochemistry, 33, 1994
2I4N
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BU of 2i4n by Molmil
Rhodopseudomonas palustris prolyl-tRNA synthetase in complex with CysAMS
Descriptor: 5'-O-(N-(L-CYSTEINYL)-SULFAMOYL)ADENOSINE, Proline-tRNA ligase
Authors:Crepin, T, Yaremchuk, A, Tukalo, M, Cusack, S.
Deposit date:2006-08-22
Release date:2006-10-24
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structures of Two Bacterial Prolyl-tRNA Synthetases with and without a cis-Editing Domain.
Structure, 14, 2006
2I4M
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BU of 2i4m by Molmil
Rhodopseudomonas palustris prolyl-tRNA synthetase in complex with ProAMS
Descriptor: '5'-O-(N-(L-PROLYL)-SULFAMOYL)ADENOSINE, Proline-tRNA ligase
Authors:Crepin, T, Yaremchuk, A, Tukalo, M, Cusack, S.
Deposit date:2006-08-22
Release date:2006-10-24
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of Two Bacterial Prolyl-tRNA Synthetases with and without a cis-Editing Domain.
Structure, 14, 2006
4IW1
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BU of 4iw1 by Molmil
HSA-fructose complex
Descriptor: D-fructose, PHOSPHATE ION, Serum albumin, ...
Authors:Wang, Y, Yu, H, Shi, X, Huang, M.
Deposit date:2013-01-23
Release date:2013-04-24
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Structural mechanism of ring-opening reaction of glucose by human serum albumin
J.Biol.Chem., 288, 2013
7Z71
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BU of 7z71 by Molmil
Crystal structure of p63 DBD in complex with darpin C14
Descriptor: Darpin C14, Isoform 4 of Tumor protein 63, ZINC ION
Authors:Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2022-03-14
Release date:2022-07-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Designed Ankyrin Repeat Proteins as a tool box for analyzing p63.
Cell Death Differ., 29, 2022
7Z73
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BU of 7z73 by Molmil
Crystal structure of p63 tetramerization domain in complex with darpin 8F1
Descriptor: Darpin 8F1, Isoform 2 of Tumor protein 63
Authors:Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC)
Deposit date:2022-03-14
Release date:2022-07-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Designed Ankyrin Repeat Proteins as a tool box for analyzing p63.
Cell Death Differ., 29, 2022
7Z2E
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BU of 7z2e by Molmil
Cryo-EM structure of NNRTI resistant M184I/E138K mutant HIV-1 reverse transcriptase with a DNA aptamer in complex with rilpivirine
Descriptor: 4-{[4-({4-[(E)-2-cyanoethenyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile, DNA (38-MER), Reverse transcriptase/ribonuclease H, ...
Authors:Singh, A.K, Das, K.
Deposit date:2022-02-26
Release date:2022-07-20
Last modified:2024-07-17
Method:ELECTRON MICROSCOPY (3.45 Å)
Cite:Cryo-EM structures of wild-type and E138K/M184I mutant HIV-1 RT/DNA complexed with inhibitors doravirine and rilpivirine.
Proc.Natl.Acad.Sci.USA, 119, 2022
7YTA
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BU of 7yta by Molmil
crystal structure of NtAGDP3 AGD1-2 in complex with an H3K9me2 peptide
Descriptor: AGDP3 AGD1-2, H3(1-15)K9me2 peptide
Authors:Zhou, X, Du, J.
Deposit date:2022-08-13
Release date:2022-10-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:The H3K9me2-binding protein AGDP3 limits DNA methylation and transcriptional gene silencing in Arabidopsis.
J Integr Plant Biol, 64, 2022
4NZ4
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BU of 4nz4 by Molmil
Structure of Vibrio cholerae chitin de-N-acetylase in complex with 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE (NDG) and zinc ion
Descriptor: 2-acetamido-2-deoxy-alpha-D-glucopyranose, ACETATE ION, CALCIUM ION, ...
Authors:Albesa-Jove, D, Andres, E, Biarnes, X, Planas, A, Guerin, M.E.
Deposit date:2013-12-11
Release date:2014-08-13
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.944 Å)
Cite:Structural basis of chitin oligosaccharide deacetylation.
Angew.Chem.Int.Ed.Engl., 53, 2014
4O46
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BU of 4o46 by Molmil
14-3-3-gamma in complex with influenza NS1 C-terminal tail phosphorylated at S228
Descriptor: 14-3-3 protein gamma, Nonstructural protein 1, UNKNOWN ATOM OR ION, ...
Authors:Qin, S, Liu, Y, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2013-12-18
Release date:2014-04-30
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1.
Nat Commun, 5, 2014
4NW2
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BU of 4nw2 by Molmil
Tandem chromodomains of human CHD1 in complex with Influenza virus NS1 C-terminal tail trimethylated at K229
Descriptor: Chromodomain-helicase-DNA-binding protein 1, GLYCEROL, Nonstructural protein 1, ...
Authors:Qin, S, Tempel, W, Xu, C, El Bakkouri, M, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
Deposit date:2013-12-05
Release date:2014-01-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1.
Nat Commun, 5, 2014
4NZ3
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BU of 4nz3 by Molmil
Structure of Vibrio cholerae chitin de-N-acetylase in complex with DI(N-ACETYL-D-GLUCOSAMINE) (CBS) in P 21 21 21
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Deacetylase DA1, ...
Authors:Albesa-Jove, D, Andres, E, Biarnes, X, Planas, A, Guerin, M.E.
Deposit date:2013-12-11
Release date:2014-08-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.114 Å)
Cite:Structural basis of chitin oligosaccharide deacetylation.
Angew.Chem.Int.Ed.Engl., 53, 2014
7Z8E
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BU of 7z8e by Molmil
Crystal structure of the substrate-binding protein YejA from S. meliloti in complex with peptide fragment
Descriptor: 1,2-ETHANEDIOL, ABC transporter substrate-binding protein, GLY-SER-ASP-VAL-ALA, ...
Authors:Morera, S, Vigouroux, V, Travin, D.Y.
Deposit date:2022-03-17
Release date:2023-02-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Dual-Uptake Mode of the Antibiotic Phazolicin Prevents Resistance Acquisition by Gram-Negative Bacteria.
Mbio, 14, 2023
4ND2
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BU of 4nd2 by Molmil
Crystal structure of the lactate dehydrogenase from cryptosporidium parvum complexed with substrate (pyruvic acid) and cofactor analog (3-acetylpyridine adenine dinucleotide)
Descriptor: 3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE, GLYCEROL, Lactate dehydrogenase, ...
Authors:Chattopadhyay, D, Cook, W.J.
Deposit date:2013-10-25
Release date:2014-12-17
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Biochemical and structural characterization of Cryptosporidium parvum Lactate dehydrogenase.
Int.J.Biol.Macromol., 74C, 2014
4ND1
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BU of 4nd1 by Molmil
Crystal structure of the lactate dehydrogenase from cryptosporidium parvum complexed with cofactor (b-nicotinamide adenine dinucleotide) and inhibitor (oxamic acid)
Descriptor: GLYCEROL, Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase, ...
Authors:Chattopadhyay, D, Cook, W.J.
Deposit date:2013-10-25
Release date:2014-12-17
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Biochemical and structural characterization of Cryptosporidium parvum Lactate dehydrogenase.
Int.J.Biol.Macromol., 74C, 2014
7YPP
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BU of 7ypp by Molmil
Structural basis of a superoxide dismutase from a tardigrade, Ramazzottius varieornatus strain YOKOZUNA-1.
Descriptor: CALCIUM ION, COPPER (II) ION, Superoxide dismutase [Cu-Zn], ...
Authors:Sim, K.-S, Fukuda, Y, Inoue, T.
Deposit date:2022-08-04
Release date:2023-07-26
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of a superoxide dismutase from a tardigrade: Ramazzottius varieornatus strain YOKOZUNA-1.
Acta Crystallogr.,Sect.F, 79, 2023

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