PDB: 4068 resultsInfo pagesStatus searchChemie searchBIRD

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3QK1	Crystal Structure of Enterokinase-like Trypsin Variant Descriptor: 1,2-ETHANEDIOL, BENZAMIDINE, CALCIUM ION, ... Authors: Schoepfel, M, Tziridis, A, Arnold, U, Stubbs, M.T. Deposit date: 2011-01-31 Release date: 2011-03-23 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.08 Å) Cite: Towards a restriction proteinase: construction of a self-activating enzyme. Chembiochem, 12, 2011
2G5N	Indole-amidine Complexes with Bovine Trypsin Descriptor: 2-(3-METHYLPHENYL)-1H-INDOLE-5-CARBOXIMIDAMIDE, CALCIUM ION, Cationic trypsin, ... Authors: Kline, A.D, Briggs, S.L, Subramaniam, S. Deposit date: 2006-02-23 Release date: 2006-08-29 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.51 Å) Cite: Ligand Epitoping By Proton NMR Chemical Shift Differences To be published
2FX4	Bovine trypsin bound by 4-piperidinebutyrate to make acylenzyme complex Descriptor: 4-PIPERIDINEBUTYRATE, CALCIUM ION, trypsin Authors: Katz, B.A. Deposit date: 2006-02-03 Release date: 2006-02-14 Last modified: 2017-10-18 Method: X-RAY DIFFRACTION (1.65 Å) Cite: Structure-guided design of Peptide-based tryptase inhibitors. Biochemistry, 45, 2006
2G8T	Indole-amidine Complexes with Bovine Trypsin Descriptor: 2-(2-METHYLPHENYL)-1H-INDOLE-5-CARBOXIMIDAMIDE, CALCIUM ION, Cationic trypsin, ... Authors: Kline, A.D, Briggs, S.L, Subramaniam, S. Deposit date: 2006-03-03 Release date: 2006-09-05 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.41 Å) Cite: Ligand Epitoping By Proton NMR Chemical Shift Differences To be published
2FX6	bovine trypsin complexed with 2-aminobenzamidazole Descriptor: 2H-BENZOIMIDAZOL-2-YLAMINE, CALCIUM ION, Trypsin Authors: Katz, B.A. Deposit date: 2006-02-03 Release date: 2006-02-14 Last modified: 2017-10-18 Method: X-RAY DIFFRACTION (1.57 Å) Cite: Structure-guided design of Peptide-based tryptase inhibitors. Biochemistry, 45, 2006
2G5V	Indole-amidine Complexes with Bovine Trypsin Descriptor: 2-(2-METHYLPHENYL)-1H-INDOLE-6-CARBOXIMIDAMIDE, CALCIUM ION, Cationic trypsin Authors: Kline, A.D, Briggs, S.L, Subramaniam, S. Deposit date: 2006-02-23 Release date: 2006-08-29 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Ligand Epitoping By Proton NMR Chemical Shift Differences To be published
2G55	Anomalous substructure of trypsin (P3121) Descriptor: CALCIUM ION, CHLORIDE ION, Cationic trypsin Authors: Mueller-Dieckmann, C, Weiss, M.S. Deposit date: 2006-02-22 Release date: 2007-02-20 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.82 Å) Cite: On the routine use of soft X-rays in macromolecular crystallography. Part IV. Efficient determination of anomalous substructures in biomacromolecules using longer X-ray wavelengths. Acta Crystallogr.,Sect.D, 63, 2007
1UMA	ALPHA-THROMBIN (HIRUGEN) COMPLEXED WITH NA-(N,N-DIMETHYLCARBAMOYL)-ALPHA-AZALYSINE Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-THROMBIN, HIRUDIN I, ... Authors: Nardini, M, Pesce, A, Rizzi, M, Casale, E, Ferraccioli, R, Balliano, G, Milla, P, Ascenzi, P, Bolognesi, M. Deposit date: 1996-03-26 Release date: 1996-11-08 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (2 Å) Cite: Human alpha-thrombin inhibition by the active site titrant N alpha-(N,N-dimethylcarbamoyl)-alpha-azalysine p-nitrophenyl ester: a comparative kinetic and X-ray crystallographic study. J.Mol.Biol., 258, 1996
3A7V	Crystal Structure of Trypsin complexed with 3-formylbenzimidamide Descriptor: 3-formylbenzenecarboximidamide, CALCIUM ION, Cationic trypsin, ... Authors: Yamane, J, Yao, M, Tanaka, I. Deposit date: 2009-10-05 Release date: 2010-09-29 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.75 Å) Cite: In-Crystal Chemical Ligation for Drug Discovery To be Published
3A7W	Crystal Structure of Trypsin complexed with (E)-4-((tetrahydro-2H-pyran-2-yloxyimino)methyl)benzimidamide (soaking 4hours) Descriptor: (E)-4-((tetrahydro-2H-pyran-2-yloxyimino)methyl)benzimidamide, CALCIUM ION, Cationic trypsin, ... Authors: Yamane, J, Yao, M, Tanaka, I. Deposit date: 2009-10-05 Release date: 2010-09-29 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.75 Å) Cite: In-Crystal Chemical Ligation for Drug Discovery To be Published
3A87	Crystal Structure of Trypsin complexed with (E)-4-((2-nicotinoylhydrazono)methyl)benzimidamide (soaking 5 minutes) Descriptor: (E)-4-((2-nicotinoylhydrazono)methyl)benzimidamide, CALCIUM ION, Cationic trypsin, ... Authors: Yamane, J, Yao, M, Tanaka, I. Deposit date: 2009-10-05 Release date: 2010-09-29 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.75 Å) Cite: In-Crystal Chemical Ligation for Drug Discovery To be Published
3A88	Crystal Structure of Trypsin complexed with (E)-4-((2-nicotinoylhydrazono)methyl)benzimidamide (soaking 30 minutes) Descriptor: (E)-4-((2-nicotinoylhydrazono)methyl)benzimidamide, CALCIUM ION, Cationic trypsin, ... Authors: Yamane, J, Yao, M, Tanaka, I. Deposit date: 2009-10-05 Release date: 2010-09-29 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.75 Å) Cite: In-Crystal Chemical Ligation for Drug Discovery To be Published
3A82	Crystal Structure of Trypsin complexed with pre-synthesized (E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid Descriptor: (E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid, CALCIUM ION, Cationic trypsin, ... Authors: Yamane, J, Yao, M, Tanaka, I. Deposit date: 2009-10-05 Release date: 2010-09-29 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.75 Å) Cite: In-Crystal Chemical Ligation for Drug Discovery To be Published
3A8D	Crystal Structure of Trypsin complexed with (E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid (under aniline-free condition) Descriptor: (E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid, CALCIUM ION, Cationic trypsin, ... Authors: Yamane, J, Yao, M, Tanaka, I. Deposit date: 2009-10-05 Release date: 2010-09-29 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.75 Å) Cite: In-Crystal Chemical Ligation for Drug Discovery To be Published
3A7T	Crystal Structure of Trypsin complexed with 4-formylbenzimidamide Descriptor: 4-formylbenzenecarboximidamide, CALCIUM ION, Cationic trypsin, ... Authors: Yamane, J, Yao, M, Tanaka, I. Deposit date: 2009-10-05 Release date: 2010-09-29 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.75 Å) Cite: In-Crystal Chemical Ligation for Drug Discovery To be Published
3A83	Crystal Structure of Trypsin complexed with pre-synthesized (E)-4-((2-nicotinoylhydrazono)methyl)benzimidamide Descriptor: (E)-4-((2-nicotinoylhydrazono)methyl)benzimidamide, CALCIUM ION, Cationic trypsin, ... Authors: Yamane, J, Yao, M, Tanaka, I. Deposit date: 2009-10-05 Release date: 2010-09-29 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.78 Å) Cite: In-Crystal Chemical Ligation for Drug Discovery To be Published
2D8W	Structure of HYPER-VIL-trypsin Descriptor: CALCIUM ION, Cationic trypsin, IODIDE ION Authors: Miyatake, H, Hasegawa, T, Yamano, A. Deposit date: 2005-12-08 Release date: 2006-07-11 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2 Å) Cite: New methods to prepare iodinated derivatives by vaporizing iodine labelling (VIL) and hydrogen peroxide VIL (HYPER-VIL) ACTA CRYSTALLOGR.,SECT.D, 62, 2006
3A84	Crystal Structure of Trypsin complexed with(E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid (soaking 5 seconds) Descriptor: (E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid, CALCIUM ION, Cationic trypsin, ... Authors: Yamane, J, Yao, M, Tanaka, I. Deposit date: 2009-10-05 Release date: 2010-09-29 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.75 Å) Cite: In-Crystal Chemical Ligation for Drug Discovery To be Published
3A89	Crystal Structure of Trypsin complexed with (E)-4-((2-nicotinoylhydrazono)methyl)benzimidamide (soaking 4 hours) Descriptor: (E)-4-((2-nicotinoylhydrazono)methyl)benzimidamide, CALCIUM ION, Cationic trypsin, ... Authors: Yamane, J, Yao, M, Tanaka, I. Deposit date: 2009-10-05 Release date: 2010-09-29 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.8 Å) Cite: In-Crystal Chemical Ligation for Drug Discovery To be Published
3A7Z	Crystal Structure of Trypsin complexed with (E)-4-((1-methylpiperidin-4-yloxyimino)methyl)benzimidamide (soaking 3hours) Descriptor: (E)-4-((1-methylpiperidin-4-yloxyimino)methyl)benzimidamide, CALCIUM ION, Cationic trypsin, ... Authors: Yamane, J, Yao, M, Tanaka, I. Deposit date: 2009-10-05 Release date: 2010-09-29 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.8 Å) Cite: In-Crystal Chemical Ligation for Drug Discovery To be Published
3A85	Crystal Structure of Trypsin complexed with (E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid (soaking 15 seconds) Descriptor: (E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid, CALCIUM ION, Cationic trypsin, ... Authors: Yamane, J, Yao, M, Tanaka, I. Deposit date: 2009-10-05 Release date: 2010-09-29 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.75 Å) Cite: In-Crystal Chemical Ligation for Drug Discovery To be Published
3A80	Crystal Structure of Trypsin complexed with (E)-2-(4-carbamimidoylbenzylideneaminooxy)-2-methylpropanoic acid (soaking 40seconds) Descriptor: (E)-2-(4-carbamimidoylbenzylideneaminooxy)-2-methylpropanoic acid, CALCIUM ION, Cationic trypsin Authors: Yamane, J, Yao, M, Tanaka, I. Deposit date: 2009-10-05 Release date: 2010-09-29 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.75 Å) Cite: In-Crystal Chemical Ligation for Drug Discovery To be Published
3A8C	Crystal Structure of Trypsin complexed with (E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid (soaking with mixture of [(E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid] and [(E)-2-(4-carbamimidoylbenzylideneaminooxy)-2-methylpropanoic acid]) Descriptor: (E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid, CALCIUM ION, Cationic trypsin Authors: Yamane, J, Yao, M, Tanaka, I. Deposit date: 2009-10-05 Release date: 2010-09-29 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.85 Å) Cite: In-Crystal Chemical Ligation for Drug Discovery To be Published
3A81	Crystal Structure of Trypsin complexed with (E)-4-((2-nicotinoylhydrazono)methyl)benzimidamide (soaking 8 hours) Descriptor: (E)-4-((2-nicotinoylhydrazono)methyl)benzimidamide, CALCIUM ION, Cationic trypsin, ... Authors: Yamane, J, Yao, M, Tanaka, I. Deposit date: 2009-10-05 Release date: 2010-09-29 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.78 Å) Cite: In-Crystal Chemical Ligation for Drug Discovery To be Published
3A7X	Crystal Structure of Trypsin complexed with (E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid (soaking 45seconds) Descriptor: (E)-2-(4-carbamimidoylbenzylideneaminooxy)acetic acid, CALCIUM ION, Cationic trypsin, ... Authors: Yamane, J, Yao, M, Tanaka, I. Deposit date: 2009-10-05 Release date: 2010-09-29 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.75 Å) Cite: In-Crystal Chemical Ligation for Drug Discovery To be Published

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