5JYM
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![BU of 5jym by Molmil](/molmil-images/mine/5jym) | Human P-cadherin EC12 with scFv TSP11 bound | Descriptor: | Antibody scFv TSP11, CALCIUM ION, Cadherin-3 | Authors: | Caaveiro, J.M.M, Kudo, S, Tsumoto, K. | Deposit date: | 2016-05-14 | Release date: | 2016-12-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Disruption of cell adhesion by an antibody targeting the cell-adhesive intermediate (X-dimer) of human P-cadherin Sci Rep, 7, 2017
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6K4Z
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![BU of 6k4z by Molmil](/molmil-images/mine/6k4z) | Single-chain Fv antibody of C6 COMPLEXED WITH 2-(4-HYDROXY-3-NITROPHENYL)ACETIC ACID | Descriptor: | 2-(4-HYDROXY-3-NITROPHENYL)ACETIC ACID, GLYCEROL, SULFATE ION, ... | Authors: | Nishiguchi, A, Numoto, N, Ito, N, Azuma, T, Oda, M. | Deposit date: | 2019-05-27 | Release date: | 2019-09-18 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Three-dimensional structure of a high affinity anti-(4-hydroxy-3-nitrophenyl)acetyl antibody possessing a glycine residue at position 95 of the heavy chain. Mol.Immunol., 114, 2019
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1P4I
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![BU of 1p4i by Molmil](/molmil-images/mine/1p4i) | Crystal Structure of scFv against peptide GCN4 | Descriptor: | ANTIBODY VARIABLE LIGHT CHAIN, antibody variable heavy chain | Authors: | Zahnd, C, Spinelli, S, Luginbuhl, B, Jermutus, L, Amstutz, P, Cambillau, C, Pluckthun, A. | Deposit date: | 2003-04-23 | Release date: | 2004-05-04 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Directed in Vitro Evolution and Crystallographic Analysis of a Peptide-binding Single Chain Antibody Fragment (scFv) with Low Picomolar Affinity. J.Biol.Chem., 279, 2004
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4NRZ
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![BU of 4nrz by Molmil](/molmil-images/mine/4nrz) | |
4NRY
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![BU of 4nry by Molmil](/molmil-images/mine/4nry) | |
4NRX
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![BU of 4nrx by Molmil](/molmil-images/mine/4nrx) | |
8JEP
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![BU of 8jep by Molmil](/molmil-images/mine/8jep) | Crystal structure of Ociperlimab | Descriptor: | antibody heavy chain, antibody light chain | Authors: | Sun, J, Zhang, X.X, Song, J. | Deposit date: | 2023-05-16 | Release date: | 2024-02-28 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab. Structure, 32, 2024
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8JEQ
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![BU of 8jeq by Molmil](/molmil-images/mine/8jeq) | Crystal structure of Tiragolumab | Descriptor: | antibody heavy chain, antibody light chain | Authors: | Sun, J, Zhang, X.X, Song, J. | Deposit date: | 2023-05-16 | Release date: | 2024-02-28 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Structural insights into the unique pH-responsive characteristics of the anti-TIGIT therapeutic antibody Ociperlimab. Structure, 32, 2024
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2BX5
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![BU of 2bx5 by Molmil](/molmil-images/mine/2bx5) | Is FR1 the antibody's Achillies heel | Descriptor: | VD9 VKI LIGHT-CHAIN | Authors: | James, L.C. | Deposit date: | 2005-07-22 | Release date: | 2006-11-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Beta-Edge Interactions in a Pentadecameric Human Antibody Vkappa Domain. J.Mol.Biol., 367, 2007
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3U6R
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![BU of 3u6r by Molmil](/molmil-images/mine/3u6r) | Three dimensional structure of broadly neutralizing anti - Hepatitis C virus (HCV) glycoprotein E2 single chain FV fragment 1:7 | Descriptor: | Antibody 1:7 (Heavy chain), Antibody 1:7 (Light chain), SULFATE ION | Authors: | Gilmartin, A.A, Lamp, B, Ruemenapf, T, Persson, A.A, Rey, F.A, Krey, T. | Deposit date: | 2011-10-12 | Release date: | 2012-01-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.67 Å) | Cite: | High-level secretion of recombinant monomeric murine and human single-chain Fv antibodies from Drosophila S2 cells. Protein Eng.Des.Sel., 25, 2012
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4XNM
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![BU of 4xnm by Molmil](/molmil-images/mine/4xnm) | Antibody Influenza H5 Complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, H5.3 FAB Heavy Chain, H5.3 FAB Light Chain, ... | Authors: | Winarski, K.L, Spiler, B.W. | Deposit date: | 2015-01-15 | Release date: | 2015-07-15 | Last modified: | 2022-03-30 | Method: | X-RAY DIFFRACTION (2.51 Å) | Cite: | Vaccine-elicited antibody that neutralizes H5N1 influenza and variants binds the receptor site and polymorphic sites. Proc.Natl.Acad.Sci.USA, 112, 2015
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5BK0
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![BU of 5bk0 by Molmil](/molmil-images/mine/5bk0) | Crystal structure of 663 Fab bound to circumsporozoite protein NANP 5-mer | Descriptor: | 663 Antibody, heavy chain, light chain, ... | Authors: | Scally, S.W, Bosch, A, Triller, G, Wardemann, H, Julien, J.P. | Deposit date: | 2017-09-12 | Release date: | 2017-12-13 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies. Immunity, 47, 2017
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7ARN
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![BU of 7arn by Molmil](/molmil-images/mine/7arn) | Crystal Structure of the Fab Fragment of a Glycosylated Lymphoma Antibody | Descriptor: | Antibody Fab Fragment Heavy Chain, Antibody Fab Fragment Light Chain, GLYCEROL, ... | Authors: | Pryce, R, Allen, J.D, Watanabe, Y, Crispin, M, Bowden, T.A. | Deposit date: | 2020-10-25 | Release date: | 2021-11-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Crystal Structure of the Fab Fragment of a Glycosylated Lymphoma Antibody To Be Published
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4B41
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![BU of 4b41 by Molmil](/molmil-images/mine/4b41) | Crystal structure of an amyloid-beta binding single chain antibody G7 | Descriptor: | ANTIBODY G7, CHLORIDE ION, GLYCEROL | Authors: | Beringer, D.X, Dorresteijn, B, Rutten, L, Wienk, H, el Khattabi, M, Kroon-Batenburg, L.M.J, Verrips, C.T. | Deposit date: | 2012-07-27 | Release date: | 2013-08-07 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.191 Å) | Cite: | Crystal Structure of an Amyloid-Beta Binding Single Chain Antibody G7 To be Published
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1ZMY
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![BU of 1zmy by Molmil](/molmil-images/mine/1zmy) | cAbBCII-10 VHH framework with CDR loops of cAbLys3 grafted on it and in complex with hen egg white lysozyme | Descriptor: | Antibody cabbcII-10:lys3, Lysozyme C | Authors: | Saerens, D, Pellis, M, Loris, R, Pardon, E, Dumoulin, M, Matagne, A, Wyns, L, Muyldermans, S, Conrath, K. | Deposit date: | 2005-05-11 | Release date: | 2005-10-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Identification of a universal VHH framework to graft non-canonical antigen-binding loops of camel single-domain antibodies J.Mol.Biol., 352, 2005
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5FCS
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![BU of 5fcs by Molmil](/molmil-images/mine/5fcs) | Diabody | Descriptor: | Diabody, SULFATE ION | Authors: | Mosyak, L, Root, A. | Deposit date: | 2015-12-15 | Release date: | 2016-12-14 | Last modified: | 2019-11-13 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Development of PF-06671008, a Highly Potent Anti-P-cadherin/Anti-CD3 Bispecific DART Molecule with Extended Half-Life for the Treatment of Cancer. Antibodies, 5, 2016
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2W65
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![BU of 2w65 by Molmil](/molmil-images/mine/2w65) | Anti citrullinated Collagen type 2 antibody acc4 in complex with a citrullinated peptide | Descriptor: | ANTI-CITRULLINATED COLLAGEN TYPE II FAB ACC4, COLLAGEN DERIVED PEPTIDE PCII-CIT1, SULFATE ION | Authors: | Uysal, H, Bockermann, R, Nandakumar, K.S, Sehnert, B, Bajtner, E, Engstrom, A, Serre, G, Burkhardt, H, Thunnissen, M.M.G.M, Holmdahl, R. | Deposit date: | 2008-12-17 | Release date: | 2009-02-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis. J. Exp. Med., 206, 2009
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2W60
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![BU of 2w60 by Molmil](/molmil-images/mine/2w60) | Anti citrullinated Collagen type 2 antibody acc4 | Descriptor: | ANTI-CITRULLINATED COLLAGEN TYPE II FAB ACC4, NITRATE ION | Authors: | Uysal, H, Bockermann, R, Nandakumar, K.S, Sehnert, B, Bajtner, E, Engstrom, A, Serre, G, Burkhardt, H, Thunnissen, M.M.G.M, Holmdahl, R. | Deposit date: | 2008-12-16 | Release date: | 2009-02-24 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis. J. Exp. Med., 206, 2009
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4XNQ
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![BU of 4xnq by Molmil](/molmil-images/mine/4xnq) | Antibody hemagglutinin Complexes | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, H5.3 Light chain, H5.3 heavy chain, ... | Authors: | Spiller, B.W, Winarski, K.L. | Deposit date: | 2015-01-15 | Release date: | 2015-07-15 | Last modified: | 2022-03-30 | Method: | X-RAY DIFFRACTION (2.001 Å) | Cite: | Vaccine-elicited antibody that neutralizes H5N1 influenza and variants binds the receptor site and polymorphic sites. Proc.Natl.Acad.Sci.USA, 112, 2015
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4XRC
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![BU of 4xrc by Molmil](/molmil-images/mine/4xrc) | Antibody hemagglutinin Complexes | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, H5.3 Fab heavy chain, H5.3 Fab light chain, ... | Authors: | Spiller, B.W, Winarski, K.L. | Deposit date: | 2015-01-20 | Release date: | 2015-07-15 | Last modified: | 2022-03-30 | Method: | X-RAY DIFFRACTION (2.74 Å) | Cite: | Vaccine-elicited antibody that neutralizes H5N1 influenza and variants binds the receptor site and polymorphic sites. Proc.Natl.Acad.Sci.USA, 112, 2015
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4P49
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![BU of 4p49 by Molmil](/molmil-images/mine/4p49) | The structure of a chicken anti-prostate specific antigen scFv | Descriptor: | ACETATE ION, Antibody scFv B8, SULFATE ION | Authors: | Conroy, P.J, Law, R.H.P, Gilgunn, S, Hearty, S, Llyod, G, Caradoc-Davies, T.T, O'Kennedy, R.J, Whisstock, J.C. | Deposit date: | 2014-03-12 | Release date: | 2014-04-23 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Reconciling the structural attributes of avian antibodies. J.Biol.Chem., 289, 2014
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1IND
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5E08
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![BU of 5e08 by Molmil](/molmil-images/mine/5e08) | Specific Recognition of a Single-stranded RNA Sequence by an Engineered Synthetic Antibody Fragment | Descriptor: | Fab Heavy Chain, Fab Light Chain, RNA | Authors: | Huang, H, Qin, D, Li, N, Shao, Y, Staley, J.P, Kossiakoff, A.A, Koide, S, Piccirilli, J.A. | Deposit date: | 2015-09-28 | Release date: | 2016-09-21 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Specific Recognition of a Single-Stranded RNA Sequence by a Synthetic Antibody Fragment. J.Mol.Biol., 428, 2016
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1INE
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8FR6
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![BU of 8fr6 by Molmil](/molmil-images/mine/8fr6) | Antibody vFP53.02 in complex with HIV-1 envelope trimer BG505 DS-SOSIP | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | Authors: | Wang, S, Kwong, P.D. | Deposit date: | 2023-01-06 | Release date: | 2023-04-19 | Last modified: | 2023-06-07 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization. J.Virol., 97, 2023
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