4NRX
Crystal Structure of HIV-1 Neutralizing Antibody m66 in complex with gp41 MPER peptide
Summary for 4NRX
Entry DOI | 10.2210/pdb4nrx/pdb |
Related | 4NRX 4NRY |
Descriptor | Envelope glycoprotein gp41, m66 Heavy Chain, m66 Light Chain, ... (4 entities in total) |
Functional Keywords | immunoglobulin, neutralizing antibody, hiv-1 gp41, membrane proximal external region, mper, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 8 |
Total formula weight | 149599.39 |
Authors | Ofek, G.,Yang, Y.,Kwong, P.D. (deposition date: 2013-11-27, release date: 2014-02-05, Last modification date: 2023-09-20) |
Primary citation | Ofek, G.,Zirkle, B.,Yang, Y.,Zhu, Z.,McKee, K.,Zhang, B.,Chuang, G.Y.,Georgiev, I.S.,O'Dell, S.,Doria-Rose, N.,Mascola, J.R.,Dimitrov, D.S.,Kwong, P.D. Structural Basis for HIV-1 Neutralization by 2F5-Like Antibodies m66 and m66.6. J.Virol., 88:2426-2441, 2014 Cited by PubMed: 24335316DOI: 10.1128/JVI.02837-13 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.21 Å) |
Structure validation
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