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4B8W
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Crystal structure of human GDP-L-fucose synthase with bound NADP and GDP, tetragonal crystal form
Descriptor: GDP-L-FUCOSE SYNTHASE, GUANOSINE-5'-DIPHOSPHATE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Vollmar, M, Krojer, T, Shafqat, N, Rojkova, A, Bunkoczi, G, Pike, A, Chaikuat, A, Carpenter, E, Yue, W.W, Kavanagh, K, von Delft, F, Weigelt, J, Arrowsmith, C.H, Bountra, C, Edwards, A, Oppermann, U.
Deposit date:2012-08-31
Release date:2012-11-21
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal Structure of Human Gdp-L-Fucose Synthase with Bound Nadp and Gdp, Tetragonal Crystal Form
To be Published
4E5Y
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BU of 4e5y by Molmil
Structure of human FX protein, the key enzyme in the biosynthesis of GDP-L-fucose
Descriptor: GDP-L-fucose synthase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Zhou, H, He, J.H.
Deposit date:2012-03-15
Release date:2013-04-17
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.37 Å)
Cite:Structure of human FX protein, the key enzyme in the biosynthesis of GDP-L-fucose
To be Published
4EJ0
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Crystal structure of ADP-L-glycero-D-manno-heptose-6-epimerase from Burkholderia thailandensis
Descriptor: ADP-L-glycero-D-manno-heptose-6-epimerase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Kim, M.S, Shin, D.H.
Deposit date:2012-04-06
Release date:2013-04-17
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.609 Å)
Cite:Structure and in silico substrate-binding mode of ADP-L-glycero-D-manno-heptose 6-epimerase from Burkholderia thailandensis.
Acta Crystallogr.,Sect.D, 69, 2013
6VO6
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Crystal Structure of Cj1427, an Essential NAD-dependent Dehydrogenase from Campylobacter jejuni, in the Presence of NADH and GDP
Descriptor: 1,2-ETHANEDIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CHLORIDE ION, ...
Authors:Anderson, T.K, Spencer, K.D, Thoden, J.B, Huddleston, J.P, Raushel, F.M, Holden, H.M.
Deposit date:2020-01-30
Release date:2020-04-01
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Analysis of Cj1427, an Essential NAD-Dependent Dehydrogenase for the Biosynthesis of the Heptose Residues in the Capsular Polysaccharides ofCampylobacter jejuni.
Biochemistry, 59, 2020
6VO8
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X-ray structure of the Cj1427 in the presence of NADH and GDP-D-glycero-D-mannoheptose, an essential NAD-dependent dehydrogenase from Campylobacter jejuni
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Putative sugar-nucleotide epimerase/dehydratease, [[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{S},5~{S},6~{S})-6-[(1~{S})-1,2-bis(oxidanyl)ethyl]-3,4,5-tris(oxidanyl)oxan-2-yl] hydrogen phosphate
Authors:Spencer, K.D, Anderson, T.K, Thoden, J.B, Huddleston, J.P, Raushel, F.M, Holden, H.M.
Deposit date:2020-01-30
Release date:2020-03-25
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Analysis of Cj1427, an Essential NAD-Dependent Dehydrogenase for the Biosynthesis of the Heptose Residues in the Capsular Polysaccharides ofCampylobacter jejuni.
Biochemistry, 59, 2020
6WJA
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UDP-GlcNAc C4-epimerase mutant S121A/Y146F from Pseudomonas protegens in complex with UDP-GalNAc
Descriptor: NAD-dependent epimerase/dehydratase family protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, URIDINE-DIPHOSPHATE-N-ACETYLGALACTOSAMINE
Authors:Marmont, L.S, Pfoh, R, Howell, P.L.
Deposit date:2020-04-13
Release date:2020-07-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.094 Å)
Cite:PelX is a UDP-N-acetylglucosamine C4-epimerase involved in Pel polysaccharide-dependent biofilm formation.
J.Biol.Chem., 295, 2020
6WJ9
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UDP-GlcNAc C4-epimerase mutant S121A/Y146F from Pseudomonas protegens in complex with UDP-GlcNAc
Descriptor: NAD-dependent epimerase/dehydratase family protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE
Authors:Marmont, L.S, Willams, R.J, Whitney, J.C, Whitfield, G.B, Robinson, H, Parsek, M.R, Nitz, M, Harrison, J.J, Howell, P.L.
Deposit date:2020-04-13
Release date:2020-07-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:PelX is a UDP-N-acetylglucosamine C4-epimerase involved in Pel polysaccharide-dependent biofilm formation.
J.Biol.Chem., 295, 2020
6WJB
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BU of 6wjb by Molmil
UDP-GlcNAc C4-epimerase from Pseudomonas protegens in complex with NAD and UDP-GlcNAc
Descriptor: NAD-dependent epimerase/dehydratase family protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE
Authors:Marmont, L.S, Pfoh, R, Robinson, H, Howell, P.L.
Deposit date:2020-04-13
Release date:2020-07-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:PelX is a UDP-N-acetylglucosamine C4-epimerase involved in Pel polysaccharide-dependent biofilm formation.
J.Biol.Chem., 295, 2020
6JYG
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Crystal Structure of L-threonine dehydrogenase from Phytophthora infestans
Descriptor: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, CITRATE ANION, L-threonine 3-dehydrogenase, ...
Authors:Yoneda, K, Sakuraba, H, Ohshima, T.
Deposit date:2019-04-26
Release date:2020-04-01
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Catalytic properties and crystal structure of UDP-galactose 4-epimerase-like l-threonine 3-dehydrogenase from Phytophthora infestans.
Enzyme.Microb.Technol., 140, 2020
6KWS
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BU of 6kws by Molmil
Crystal structure of Gre2 from Candida albicans
Descriptor: Methylglyoxal reductase (NADPH-dependent)
Authors:Nguyen, G.T, Chang, J.H.
Deposit date:2019-09-08
Release date:2020-09-09
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of NADPH-Dependent Methylglyoxal Reductase Gre2 from Candida Albicans
Crystals, 9, 2019
6KV9
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BU of 6kv9 by Molmil
MoeE5 in complex with UDP-glucuronic acid and NAD
Descriptor: MoeE5, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, URIDINE-5'-DIPHOSPHATE-GLUCURONIC ACID
Authors:Ko, T.-P, Liu, W, Sun, H, Liu, W, Chen, C.-C, Guo, R.-T.
Deposit date:2019-09-03
Release date:2019-11-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Structure of an antibiotic-synthesizing UDP-glucuronate 4-epimerase MoeE5 in complex with substrate.
Biochem.Biophys.Res.Commun., 521, 2020
6KWT
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Crystal structure of Gre2 in complex with NADPH complex from Candida albicans
Descriptor: Methylglyoxal reductase (NADPH-dependent), NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Nguyen, G.T, Chang, J.H.
Deposit date:2019-09-08
Release date:2020-09-09
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (3.02 Å)
Cite:Crystal Structure of NADPH-Dependent Methylglyoxal Reductase Gre2 from Candida Albicans
Crystals, 9, 2019
6KVC
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MoeE5 in complex with UDP-glucose and NAD
Descriptor: MoeE5, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, URIDINE-5'-DIPHOSPHATE-GLUCOSE
Authors:Ko, T.-P, Liu, W, Sun, H, Liu, W, Chen, C.-C, Guo, R.-T.
Deposit date:2019-09-04
Release date:2019-11-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structure of an antibiotic-synthesizing UDP-glucuronate 4-epimerase MoeE5 in complex with substrate.
Biochem.Biophys.Res.Commun., 521, 2020
6MFH
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BU of 6mfh by Molmil
Mutated Uronate Dehydrogenase
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Mutated Uronate Dehydrogenase, PHOSPHATE ION
Authors:Sankaran, B, Pereira, J.H, Chan, V, Zwart, P.H, Wagschal, K.
Deposit date:2018-09-11
Release date:2019-09-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Chromohalobacter salixigens uronate dehydrogenase: Directed evolution for improved thermal stability and mutant CsUDH-inc X-ray crystal structure
Process Biochem, 2020
6NBR
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BU of 6nbr by Molmil
Crystal Structure of Piper methysticum Kavalactone Reductase 1 in complex with NADP
Descriptor: Kavalactone reductase 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Pluskal, T, Weng, J.K.
Deposit date:2018-12-09
Release date:2019-06-19
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The biosynthetic origin of psychoactive kavalactones in kava.
Nat.Plants, 5, 2019
6ND7
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BU of 6nd7 by Molmil
The crystal structure of TerB co-crystallized with polyporic acid
Descriptor: 2~3~,2~6~-dihydroxy[1~1~,2~1~:2~4~,3~1~-terphenyl]-2~2~,2~5~-dione, GLYCEROL, ISOPROPYL ALCOHOL, ...
Authors:Clinger, J.A, Elshahawi, S.I, Zhang, Y, Hall, R.P, Liu, Y, Thorson, J.S, Phillips Jr, G.N.
Deposit date:2018-12-13
Release date:2019-12-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.36 Å)
Cite:Structure and Function of Terfestatin Biosynthesis Enzymes TerB and TerC
To Be Published
7C1E
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BU of 7c1e by Molmil
Crystal structure of Kluyveromyces polyspora ADH (KpADH) mutant (Y127W)
Descriptor: Epimerase domain-containing protein, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Wu, Y.F, Zhou, J.Y, Liu, Y.F, Xu, G.C, Ni, Y.
Deposit date:2020-05-03
Release date:2021-05-05
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Engineering an Alcohol Dehydrogenase from Kluyveromyces polyspora for Efficient Synthesis of Ibrutinib Intermediate
Adv.Synth.Catal., 2021
1ZZE
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BU of 1zze by Molmil
X-ray Structure of NADPH-dependent Carbonyl Reductase from Sporobolomyces salmonicolor
Descriptor: Aldehyde reductase II, SULFATE ION
Authors:Kamitori, S, Iguchi, A, Ohtaki, A, Yamada, M, Kita, K.
Deposit date:2005-06-14
Release date:2005-09-06
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray Structures of NADPH-dependent Carbonyl Reductase from Sporobolomyces salmonicolor Provide Insights into Stereoselective Reductions of Carbonyl Compounds
J.Mol.Biol., 352, 2005
7C3V
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BU of 7c3v by Molmil
Structure of a thermostable Alcohol dehydrogenase from Kluyveromyces polyspora(KpADH)
Descriptor: Alcohol dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Dai, W, Ni, Y, Xu, G, Liu, Y, Wang, Y, Zhou, J.
Deposit date:2020-05-14
Release date:2021-05-19
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.20042944 Å)
Cite:Structure of a thermostable Alcohol dehydrogenase from Kluyveromyces polyspora(KpADH)
To Be Published
5K4W
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Three-dimensional structure of L-threonine 3-dehydrogenase from Trypanosoma brucei bound to NADH and L-threonine refined to 1.72 angstroms
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, GLYCEROL, L-threonine 3-dehydrogenase, ...
Authors:Adjogatse, E.A, Erskine, P.T, Cooper, J.B.
Deposit date:2016-05-22
Release date:2018-01-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Structure and function of L-threonine-3-dehydrogenase from the parasitic protozoan Trypanosoma brucei revealed by X-ray crystallography and geometric simulations.
Acta Crystallogr D Struct Biol, 74, 2018
5K4U
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BU of 5k4u by Molmil
Three-dimensional structure of L-threonine 3-dehydrogenase from Trypanosoma brucei showing different active site loop conformations between dimer subunits, refined to 1.9 angstroms
Descriptor: ACETATE ION, GLYCEROL, L-threonine 3-dehydrogenase, ...
Authors:Adjogatse, E.K, Cooper, J.B, Erskine, P.T.
Deposit date:2016-05-22
Release date:2017-11-15
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and function of L-threonine-3-dehydrogenase from the parasitic protozoan Trypanosoma brucei revealed by X-ray crystallography and geometric simulations.
Acta Crystallogr D Struct Biol, 74, 2018
5K4Q
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BU of 5k4q by Molmil
Three-dimensional structure of L-threonine 3-dehydrogenase from Trypanosoma brucei bound to NAD+ refined to 2.3 angstroms
Descriptor: GLYCEROL, L-threonine 3-dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Adjogatse, E.K, Cooper, J.B, Erskine, P.T.
Deposit date:2016-05-21
Release date:2017-11-15
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure and function of L-threonine-3-dehydrogenase from the parasitic protozoan Trypanosoma brucei revealed by X-ray crystallography and geometric simulations.
Acta Crystallogr D Struct Biol, 74, 2018
5K4V
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Three-dimensional structure of L-threonine 3-dehydrogenase from Trypanosoma brucei bound to NAD+ refined to 2.2 angstroms
Descriptor: ACETATE ION, GLYCEROL, L-threonine 3-dehydrogenase, ...
Authors:Adjogatse, E.A, Erskine, P.T, Cooper, J.B.
Deposit date:2016-05-22
Release date:2017-11-15
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and function of L-threonine-3-dehydrogenase from the parasitic protozoan Trypanosoma brucei revealed by X-ray crystallography and geometric simulations.
Acta Crystallogr D Struct Biol, 74, 2018
5K4T
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BU of 5k4t by Molmil
Three-dimensional structure of L-threonine 3-dehydrogenase from Trypanosoma brucei refined to 2.1 angstroms
Descriptor: GLYCEROL, L-threonine 3-dehydrogenase
Authors:Adjogatse, E.K, Cooper, J.B, Erskine, P.T.
Deposit date:2016-05-22
Release date:2017-11-15
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and function of L-threonine-3-dehydrogenase from the parasitic protozoan Trypanosoma brucei revealed by X-ray crystallography and geometric simulations.
Acta Crystallogr D Struct Biol, 74, 2018
7CXT
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BU of 7cxt by Molmil
Crystal structure of a GDP-6-OMe-4-keto-L-xylo-heptose reductase from C.jejuni
Descriptor: GDP-L-fucose synthase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Kim, J.H, Kim, J.S.
Deposit date:2020-09-02
Release date:2021-04-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of a GDP-6-OMe-4-keto-L-xylo-heptose reductase from Campylobacter jejuni.
Proteins, 2021

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