PDB: 2576 resultsInfo pagesStatus searchChemie searchBIRD

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7DTA	Solution structure of the C-clamp domain from human HDBP1 in complex with DNA Descriptor: DNA (5'-D(*GP*TP*CP*CP*CP*GP*GP*CP*AP*TP*A)-3'), DNA (5'-D(*TP*AP*TP*GP*CP*CP*GP*GP*GP*AP*C)-3'), SLC2A4 regulator, ... Authors: Duan, B, Xia, B. Deposit date: 2021-01-04 Release date: 2021-07-21 Last modified: 2024-05-01 Method: SOLUTION NMR Cite: Selective Nonmethylated CpG DNA Recognition Mechanism of Cysteine Clamp Domains. J.Am.Chem.Soc., 143, 2021
3RB9	Crystal structure of the M. tuberculosis beta clamp Descriptor: DNA polymerase III subunit beta Authors: Kukshal, V, Ramachandran, R. Deposit date: 2011-03-29 Release date: 2012-04-04 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (3 Å) Cite: M. tuberculosis Sliding beta-Clamp Does Not Interact Directly with the NAD(+)-Dependent DNA Ligase Plos One, 7, 2012
3U5Z	Structure of T4 Bacteriophage clamp loader bound to the T4 clamp, primer-template DNA, and ATP analog Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA polymerase accessory protein 44, DNA polymerase accessory protein 62, ... Authors: Kelch, B.A, Makino, D.L, O'Donnell, M, Kuriyan, J. Deposit date: 2011-10-11 Release date: 2012-01-04 Method: X-RAY DIFFRACTION (3.5 Å) Cite: How a DNA polymerase clamp loader opens a sliding clamp. Science, 334, 2011
4RKI	Crystal structure of sliding beta clamp from Helicobacter pylori Descriptor: DNA polymerase III subunit beta Authors: Satyawali, P, Tarique, K.F, Abdul Rehman, S.A, Gourinath, S. Deposit date: 2014-10-13 Release date: 2016-01-13 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Structural insight into beta-Clamp and its interaction with DNA Ligase in Helicobacter pylori. Sci Rep, 6, 2016
3U61	Structure of T4 Bacteriophage Clamp Loader Bound To Closed Clamp, DNA and ATP Analog and ADP Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA polymerase accessory protein 44, DNA polymerase accessory protein 62, ... Authors: Kelch, B.A, Makino, D.L, O'Donnell, M, Kuriyan, J. Deposit date: 2011-10-11 Release date: 2012-01-04 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (3.2 Å) Cite: How a DNA polymerase clamp loader opens a sliding clamp. Science, 334, 2011
5TUP	X-ray Crystal Structure of the Aspergillus fumigatus Sliding Clamp Descriptor: Proliferating cell nuclear antigen Authors: Bruning, J.B, Marshall, A.C, Kroker, A.J, Wegener, K.L, Rajapaksha, H. Deposit date: 2016-11-06 Release date: 2017-02-22 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.602 Å) Cite: Structure of the sliding clamp from the fungal pathogen Aspergillus fumigatus (AfumPCNA) and interactions with Human p21. FEBS J., 284, 2017
7SH2	Structure of the yeast Rad24-RFC loader bound to DNA and the open 9-1-1 clamp Descriptor: ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, Crick strand, ... Authors: Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. Deposit date: 2021-10-07 Release date: 2022-03-23 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (3.23 Å) Cite: DNA is loaded through the 9-1-1 DNA checkpoint clamp in the opposite direction of the PCNA clamp. Nat.Struct.Mol.Biol., 29, 2022
7SGZ	Structure of the yeast Rad24-RFC loader bound to DNA and the closed 9-1-1 clamp Descriptor: ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, Crick strand, ... Authors: Zheng, F, Georgescu, R, Yao, Y.N, O'Donnell, M.E, Li, H. Deposit date: 2021-10-07 Release date: 2022-03-23 Last modified: 2024-06-05 Method: ELECTRON MICROSCOPY (3.17 Å) Cite: DNA is loaded through the 9-1-1 DNA checkpoint clamp in the opposite direction of the PCNA clamp. Nat.Struct.Mol.Biol., 29, 2022
3U60	Structure of T4 Bacteriophage Clamp Loader Bound To Open Clamp, DNA and ATP Analog Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA polymerase accessory protein 44, DNA polymerase accessory protein 62, ... Authors: Kelch, B.A, Makino, D.L, O'Donnell, M, Kuriyan, J. Deposit date: 2011-10-11 Release date: 2012-01-04 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (3.34 Å) Cite: How a DNA polymerase clamp loader opens a sliding clamp. Science, 334, 2011
4K3Q	E. coli sliding clamp in complex with AcQLDAF Descriptor: (ACE)QLDAF, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-04-11 Release date: 2013-05-01 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp J.Med.Chem., 56, 2013
1NJG	Nucleotide-free form of an Isolated E. coli Clamp Loader Gamma Subunit Descriptor: DNA polymerase III subunit gamma, SULFATE ION, ZINC ION Authors: Podobnik, M, Weitze, T.F, O'Donnell, M, Kuriyan, J. Deposit date: 2002-12-30 Release date: 2003-04-01 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Nucleotide-Induced Conformational Changes in an Isolated Escherichia coli DNA Polymerase III Clamp Loader Subunit Structure, 11, 2003
1NJF	Nucleotide bound form of an isolated E. coli clamp loader gamma subunit Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA polymerase III subunit gamma, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... Authors: Podobnik, M, Weitze, T.F, O'Donnell, M, Kuriyan, J. Deposit date: 2002-12-30 Release date: 2003-04-08 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Nucleotide-Induced Conformational Changes in an Isolated Escherichia coli DNA Polymerase III Clamp Loader Subunit Structure, 11, 2003
6PTR	Crystal structure of a DnaN sliding clamp (DNA polymerase III subunit beta) from Bartonella birtlesii bound to griselimycin Descriptor: 1,2-ETHANEDIOL, ACE-MVA-MP8-NZC-LEU-MP8-LEU-MVA-PRO-MLU-GLY, Beta sliding clamp, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2019-07-16 Release date: 2019-08-07 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Crystal structure of a DnaN sliding clamp (DNA polymerase III subunit beta) from Bartonella birtlesii bound to griselimycin To Be Published
6PTV	Crystal structure of a DnaN sliding clamp (DNA polymerase III subunit beta) from Rickettsia rickettsii bound to griselimycin Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ACE-MVA-MP8-NZC-LEU-MP8-LEU-MVA-PRO-MLU-GLY, Beta sliding clamp Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2019-07-16 Release date: 2019-08-07 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Crystal structure of a DnaN sliding clamp (DNA polymerase III subunit beta) from Rickettsia rickettsii bound to griselimycin To Be Published
7KC0	Structure of the Saccharomyces cerevisiae replicative polymerase delta in complex with a primer/template and the PCNA clamp Descriptor: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA (25-MER), DNA (5'-D(P*AP*TP*GP*AP*CP*CP*AP*TP*GP*AP*TP*TP*AP*CP*GP*AP*AP*TP*TP*GP*C)-3'), ... Authors: Zheng, F, Georgescu, R, Li, H, O'Donnell, M.E. Deposit date: 2020-10-04 Release date: 2020-12-02 Last modified: 2024-11-13 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structure of eukaryotic DNA polymerase delta bound to the PCNA clamp while encircling DNA. Proc.Natl.Acad.Sci.USA, 117, 2020
4K3M	E.coli sliding clamp in complex with AcALDLF peptide Descriptor: ALDLF, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... Authors: Yin, Z, Oakley, A.J. Deposit date: 2013-04-11 Release date: 2013-05-01 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structural and Thermodynamic Dissection of Linear Motif Recognition by the E. coli Sliding Clamp J.Med.Chem., 56, 2013
1JR3	Crystal Structure of the Processivity Clamp Loader Gamma Complex of E. coli DNA Polymerase III Descriptor: DNA polymerase III subunit gamma, DNA polymerase III, delta subunit, ... Authors: Jeruzalmi, D, O'Donnell, M, Kuriyan, J. Deposit date: 2001-08-10 Release date: 2001-09-26 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Crystal structure of the processivity clamp loader gamma (gamma) complex of E. coli DNA polymerase III. Cell(Cambridge,Mass.), 106, 2001
3P16	Crystal structure of DNA polymerase III sliding clamp Descriptor: DNA polymerase III subunit beta Authors: Gui, W.J, Lin, S.Q, Chen, Y.Y, Zhang, X.E, Bi, L.J, Jiang, T. Deposit date: 2010-09-30 Release date: 2011-08-24 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.89 Å) Cite: Crystal structure of DNA polymerase III beta sliding clamp from Mycobacterium tuberculosis. Biochem.Biophys.Res.Commun., 405, 2011
4K74	The UmuC subunit of the E. coli DNA polymerase V shows a unique interaction with the beta-clamp processivity factor. Descriptor: DNA polymerase III subunit beta, UmuC peptide Authors: Patoli, A.A, Winter, J.A, Bunting, K.A. Deposit date: 2013-04-16 Release date: 2013-07-17 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.5 Å) Cite: The UmuC subunit of the E. coli DNA polymerase V shows a unique interaction with the beta-clamp processivity factor. Bmc Struct.Biol., 13, 2013
8GJ3	E. coli clamp loader on primed template DNA Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA polymerase III subunit delta, DNA polymerase III subunit delta', ... Authors: Oakley, A.J, Xu, Z.-Q, Dixon, N.E. Deposit date: 2023-03-14 Release date: 2024-03-27 Last modified: 2024-10-16 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Structural characterisation of the complete cycle of sliding clamp loading in Escherichia coli. Nat Commun, 15, 2024
7TI8	Structure of the yeast clamp loader (Replication Factor C RFC) bound to the open sliding clamp (Proliferating Cell Nuclear Antigen PCNA) Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... Authors: Gaubitz, C, Liu, X, Pajak, J, Stone, N, Hayes, J, Demo, G, Kelch, B.A. Deposit date: 2022-01-13 Release date: 2022-02-16 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader. Elife, 11, 2022
7TID	Structure of the yeast clamp loader (Replication Factor C RFC) bound to the sliding clamp (Proliferating Cell Nuclear Antigen PCNA) and primer-template DNA Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(*AP*GP*AP*CP*AP*CP*TP*AP*CP*GP*AP*GP*TP*AP*CP*AP*TP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*AP*TP*GP*TP*AP*CP*TP*CP*GP*TP*AP*GP*TP*GP*TP*CP*T)-3'), ... Authors: Gaubitz, C, Liu, X, Pajak, J, Stone, N, Hayes, J, Demo, G, Kelch, B.A. Deposit date: 2022-01-13 Release date: 2022-02-16 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader. Elife, 11, 2022
7Z6H	Structure of DNA-bound human RAD17-RFC clamp loader and 9-1-1 checkpoint clamp Descriptor: Cell cycle checkpoint control protein RAD9A, Cell cycle checkpoint protein RAD1,Cell cycle checkpoint protein RAD17, Checkpoint protein HUS1, ... Authors: Day, M, Oliver, A.W, Pearl, L.H. Deposit date: 2022-03-11 Release date: 2022-05-04 Last modified: 2022-08-31 Method: ELECTRON MICROSCOPY (3.59 Å) Cite: Structure of the human RAD17-RFC clamp loader and 9-1-1 checkpoint clamp bound to a dsDNA-ssDNA junction. Nucleic Acids Res., 50, 2022
2XUR	The G157C mutation in the Escherichia coli sliding clamp specifically affects initiation of replication Descriptor: DNA POLYMERASE III SUBUNIT BETA Authors: Johnsen, L, Morigen, Dalhus, B, Bjoras, M, Flaatten, I, Waldminghaus, T, Skarstad, K. Deposit date: 2010-10-20 Release date: 2011-02-16 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The G157C Mutation in the Escherichia Coli Sliding Clamp Specifically Affects Initiation of Replication. Mol.Microbiol., 79, 2011
7TIC	Structure of the yeast clamp loader (Replication Factor C RFC) bound to the sliding clamp (Proliferating Cell Nuclear Antigen PCNA) in an autoinhibited conformation Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... Authors: Gaubitz, C, Liu, X, Pajak, J, Stone, N, Hayes, J, Demo, G, Kelch, B.A. Deposit date: 2022-01-13 Release date: 2022-02-16 Last modified: 2024-02-28 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader. Elife, 11, 2022

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