7STB
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![BU of 7stb by Molmil](/molmil-images/mine/7stb) | Closed state of Rad24-RFC:9-1-1 bound to a 5' ss/dsDNA junction | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DNA (5'-D(P*CP*GP*CP*TP*CP*CP*TP*TP*CP*CP*TP*GP*AP*CP*TP*CP*GP*TP*CP*C)-3'), ... | Authors: | Castaneda, J.C, Schrecker, M, Remus, D, Hite, R.K. | Deposit date: | 2021-11-12 | Release date: | 2022-03-23 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.72 Å) | Cite: | Mechanisms of loading and release of the 9-1-1 checkpoint clamp. Nat.Struct.Mol.Biol., 29, 2022
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7ST9
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![BU of 7st9 by Molmil](/molmil-images/mine/7st9) | Open state of Rad24-RFC:9-1-1 bound to a 5' ss/dsDNA junction | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Checkpoint protein RAD24, DNA (5'-D(P*CP*GP*CP*TP*CP*CP*TP*TP*CP*CP*TP*GP*AP*CP*TP*CP*GP*TP*CP*C)-3'), ... | Authors: | Castaneda, J.C, Schrecker, M, Remus, D, Hite, R.K. | Deposit date: | 2021-11-12 | Release date: | 2022-03-23 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.2 Å) | Cite: | Mechanisms of loading and release of the 9-1-1 checkpoint clamp. Nat.Struct.Mol.Biol., 29, 2022
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6MG2
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![BU of 6mg2 by Molmil](/molmil-images/mine/6mg2) | C-terminal bZIP domain of human C/EBPbeta with 16bp Methylated Oligonucleotide Containing Consensus Recognition Sequence-C2221 Crystal Form | Descriptor: | 1,2-ETHANEDIOL, 16-bp methylated oligonucleotide, CCAAT/enhancer-binding protein beta | Authors: | Horton, J.R, Cheng, X, Yang, J. | Deposit date: | 2018-09-12 | Release date: | 2018-12-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.928 Å) | Cite: | Structural basis for effects of CpA modifications on C/EBP beta binding of DNA. Nucleic Acids Res., 47, 2019
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1OWF
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![BU of 1owf by Molmil](/molmil-images/mine/1owf) | Crystal structure of a mutant IHF (BetaE44A) complexed with the native H' Site | Descriptor: | 5'-D(*GP*CP*TP*TP*AP*TP*CP*AP*AP*TP*TP*TP*GP*TP*TP*GP*CP*AP*CP*C)-3', 5'-D(*GP*GP*CP*CP*AP*AP*AP*AP*AP*AP*GP*CP*AP*TP*T)-3', Integration Host Factor Alpha-subunit, ... | Authors: | Lynch, T.W, Read, E.K, Mattis, A.N, Gardner, J.F, Rice, P.A. | Deposit date: | 2003-03-28 | Release date: | 2003-07-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Integration Host Factor: putting a twist on protein-DNA recognition J.Mol.Biol., 330, 2003
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1OWG
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![BU of 1owg by Molmil](/molmil-images/mine/1owg) | Crystal structure of WT IHF complexed with an altered H' site (T44A) | Descriptor: | 5'-D(*GP*CP*TP*TP*AP*TP*CP*AP*AP*TP*TP*TP*GP*TP*AP*GP*CP*AP*CP*C)-3', 5'-D(*GP*GP*CP*CP*AP*AP*AP*AP*AP*AP*GP*CP*AP*TP*T)-3', Integration Host Factor Alpha-subunit, ... | Authors: | Lynch, T.W, Read, E.K, Mattis, A.N, Gardner, J.F, Rice, P.A. | Deposit date: | 2003-03-28 | Release date: | 2003-07-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Integration Host Factor: putting a twist on protein-DNA recognition J.Mol.Biol., 330, 2003
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3OQO
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![BU of 3oqo by Molmil](/molmil-images/mine/3oqo) | Ccpa-hpr-ser46p-syn cre | Descriptor: | 5'-D(*CP*TP*GP*AP*AP*AP*GP*CP*GP*CP*TP*AP*AP*CP*AP*G)-3', 5'-D(*CP*TP*GP*TP*TP*AP*GP*CP*GP*CP*TP*TP*TP*CP*AP*G)-3', Catabolite control protein A, ... | Authors: | schumacher, M.A, Sprehe, M, Bartholomae, M, Hillen, W, Brennan, R.G. | Deposit date: | 2010-09-03 | Release date: | 2011-10-26 | Last modified: | 2014-04-09 | Method: | X-RAY DIFFRACTION (2.97 Å) | Cite: | Structures of carbon catabolite protein A-(HPr-Ser46-P) bound to diverse catabolite response element sites reveal the basis for high-affinity binding to degenerate DNA operators. Nucleic Acids Res., 39, 2011
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3OQM
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![BU of 3oqm by Molmil](/molmil-images/mine/3oqm) | structure of ccpa-hpr-ser46p-ackA2 complex | Descriptor: | 5'-D(*TP*TP*GP*AP*TP*AP*AP*CP*GP*CP*TP*TP*AP*CP*AP*A)-3', 5'-D(*TP*TP*GP*TP*AP*AP*GP*CP*GP*TP*TP*AP*TP*CP*AP*A)-3', Catabolite control protein A, ... | Authors: | Schumacher, M.A, Sprehe, M, Bartholomae, M, Hillen, W, Brennan, R.G. | Deposit date: | 2010-09-03 | Release date: | 2010-12-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.96 Å) | Cite: | Structures of carbon catabolite protein A-(HPr-Ser46-P) bound to diverse catabolite response element sites reveal the basis for high-affinity binding to degenerate DNA operators. Nucleic Acids Res., 39, 2011
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8BAS
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![BU of 8bas by Molmil](/molmil-images/mine/8bas) | E. coli C7 DarT1 in complex with carba-NAD and DNA | Descriptor: | 1,2-ETHANEDIOL, CARBA-NICOTINAMIDE-ADENINE-DINUCLEOTIDE, DNA (5'-D(*AP*AP*GP*AP*C)-3'), ... | Authors: | Schuller, M, Ariza, A. | Deposit date: | 2022-10-11 | Release date: | 2023-07-12 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Molecular basis for the reversible ADP-ribosylation of guanosine bases. Mol.Cell, 83, 2023
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8P5E
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![BU of 8p5e by Molmil](/molmil-images/mine/8p5e) | |
3OQN
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![BU of 3oqn by Molmil](/molmil-images/mine/3oqn) | Structure of ccpa-hpr-ser46-p-gntr-down cre | Descriptor: | 5'-D(*AP*TP*GP*GP*TP*AP*CP*CP*GP*CP*TP*TP*TP*CP*AP*A)-3', 5'-D(*TP*TP*GP*AP*AP*AP*GP*CP*GP*GP*TP*AP*CP*CP*AP*T)-3', Catabolite control protein A, ... | Authors: | Schumacher, M.A, Sprehe, M, Bartholomae, M, Hillen, W, Brennan, R.G. | Deposit date: | 2010-09-03 | Release date: | 2010-12-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structures of carbon catabolite protein A-(HPr-Ser46-P) bound to diverse catabolite response element sites reveal the basis for high-affinity binding to degenerate DNA operators. Nucleic Acids Res., 39, 2011
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4TZ0
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![BU of 4tz0 by Molmil](/molmil-images/mine/4tz0) | DEAD-box helicase Mss116 bound to ssRNA and GDP-BeF | Descriptor: | ATP-dependent RNA helicase MSS116, mitochondrial, BERYLLIUM TRIFLUORIDE ION, ... | Authors: | Mallam, A.L, Sidote, D.J, Lambowitz, A.M. | Deposit date: | 2014-07-09 | Release date: | 2014-12-31 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Molecular insights into RNA and DNA helicase evolution from the determinants of specificity for a DEAD-box RNA helicase. Elife, 3, 2014
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8WR4
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![BU of 8wr4 by Molmil](/molmil-images/mine/8wr4) | Structure of CbCas9-PcrIIC1 complex bound to 62-bp DNA substrate (non-targeting complex) | Descriptor: | CbCas9 effector-1, DNA (62-MER), MAGNESIUM ION, ... | Authors: | Zhang, S, Lin, S, Liu, J.J.G. | Deposit date: | 2023-10-13 | Release date: | 2024-06-05 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (3.07 Å) | Cite: | Pro-CRISPR PcrIIC1-associated Cas9 system for enhanced bacterial immunity. Nature, 630, 2024
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4TYW
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![BU of 4tyw by Molmil](/molmil-images/mine/4tyw) | DEAD-box helicase Mss116 bound to ssRNA and ADP-BeF | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase MSS116, mitochondrial, ... | Authors: | Mallam, A.L, Sidote, D.J, Lambowitz, A.M. | Deposit date: | 2014-07-09 | Release date: | 2014-12-31 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.197 Å) | Cite: | Molecular insights into RNA and DNA helicase evolution from the determinants of specificity for a DEAD-box RNA helicase. Elife, 3, 2014
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4TZ6
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![BU of 4tz6 by Molmil](/molmil-images/mine/4tz6) | DEAD-box helicase Mss116 bound to ssRNA and UDP-BeF | Descriptor: | ATP-dependent RNA helicase MSS116, mitochondrial, BERYLLIUM TRIFLUORIDE ION, ... | Authors: | Mallam, A.L, Sidote, D.J, Lambowitz, A.M. | Deposit date: | 2014-07-09 | Release date: | 2015-01-28 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.209 Å) | Cite: | Molecular insights into RNA and DNA helicase evolution from the determinants of specificity for a DEAD-box RNA helicase. Elife, 3, 2014
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4TYY
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![BU of 4tyy by Molmil](/molmil-images/mine/4tyy) | DEAD-box helicase Mss116 bound to ssRNA and CDP-BeF | Descriptor: | ATP-dependent RNA helicase MSS116, mitochondrial, BERYLLIUM TRIFLUORIDE ION, ... | Authors: | Mallam, A.L, Sidote, D.J, Lambowitz, A.M. | Deposit date: | 2014-07-09 | Release date: | 2014-12-31 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.74 Å) | Cite: | Molecular insights into RNA and DNA helicase evolution from the determinants of specificity for a DEAD-box RNA helicase. Elife, 3, 2014
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7EU0
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![BU of 7eu0 by Molmil](/molmil-images/mine/7eu0) | The cryo-EM structure of A. thaliana Pol IV-RDR2 backtracked complex | Descriptor: | DNA (33-MER), DNA (5'-D(*CP*TP*GP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*GP*AP*GP*TP*G)-3'), DNA-directed RNA polymerase IV subunit 1, ... | Authors: | Fang, C.L, Wu, X.X, Huang, K, Zhang, Y. | Deposit date: | 2021-05-15 | Release date: | 2021-12-29 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.16 Å) | Cite: | Pol IV and RDR2: A two-RNA-polymerase machine that produces double-stranded RNA. Science, 374, 2021
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7EU1
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![BU of 7eu1 by Molmil](/molmil-images/mine/7eu1) | The cryo-EM structure of A. thaliana Pol IV-RDR2 holoenzyme | Descriptor: | DNA-directed RNA polymerase IV subunit 1, DNA-directed RNA polymerases II and IV subunit 5A, DNA-directed RNA polymerases II, ... | Authors: | Fang, C.L, Wu, X.X, Huang, K, Zhang, Y. | Deposit date: | 2021-05-15 | Release date: | 2021-12-29 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.86 Å) | Cite: | Pol IV and RDR2: A two-RNA-polymerase machine that produces double-stranded RNA. Science, 374, 2021
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8X22
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![BU of 8x22 by Molmil](/molmil-images/mine/8x22) | HIV-1 reverse transcriptase mutant Q151M/Y115F/F116Y/L74V:DNA:dGTP ternary complex | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA/RNA (38-MER), GLYCEROL, ... | Authors: | Yasutake, Y, Hattori, S.I, Mitsuya, H. | Deposit date: | 2023-11-09 | Release date: | 2024-07-17 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Deviated binding of anti-HBV nucleoside analog E-CFCP-TP to the reverse transcriptase active site attenuates the effect of drug-resistant mutations. Sci Rep, 14, 2024
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6X6D
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![BU of 6x6d by Molmil](/molmil-images/mine/6x6d) | |
6QX5
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![BU of 6qx5 by Molmil](/molmil-images/mine/6qx5) | Crystal structure of T7 bacteriophage portal protein, 12mer, closed valve | Descriptor: | Portal protein | Authors: | Fabrega-Ferrer, M, Cuervo, A, Machon, C, Fernandez, F.J, Perez-Luque, R, Pous, J, Vega, M.C, Carrascosa, J.L, Coll, M. | Deposit date: | 2019-03-07 | Release date: | 2019-09-04 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Structures of T7 bacteriophage portal and tail suggest a viral DNA retention and ejection mechanism. Nat Commun, 10, 2019
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6R21
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![BU of 6r21 by Molmil](/molmil-images/mine/6r21) | Cryo-EM structure of T7 bacteriophage fiberless tail complex | Descriptor: | Portal protein, Tail tubular protein gp11, Tail tubular protein gp12 | Authors: | Cuervo, A, Fabrega-Ferrer, M, Machon, C, Conesa, J.J, Perez-Ruiz, M, Coll, M, Carrascosa, J.L. | Deposit date: | 2019-03-15 | Release date: | 2019-09-04 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | Structures of T7 bacteriophage portal and tail suggest a viral DNA retention and ejection mechanism. Nat Commun, 10, 2019
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1F36
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![BU of 1f36 by Molmil](/molmil-images/mine/1f36) | |
7TEA
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![BU of 7tea by Molmil](/molmil-images/mine/7tea) | Crystal structure of S. aureus GlnR-DNA complex | Descriptor: | CALCIUM ION, DNA (5'-D(*CP*GP*TP*GP*TP*CP*AP*GP*AP*TP*AP*AP*TP*CP*TP*GP*AP*CP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*GP*TP*CP*AP*GP*AP*TP*TP*AP*TP*CP*TP*GP*AP*CP*AP*CP*G)-3'), ... | Authors: | Schumacher, M.A. | Deposit date: | 2022-01-04 | Release date: | 2022-06-29 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria. Nat Commun, 13, 2022
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7TIC
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![BU of 7tic by Molmil](/molmil-images/mine/7tic) | Structure of the yeast clamp loader (Replication Factor C RFC) bound to the sliding clamp (Proliferating Cell Nuclear Antigen PCNA) in an autoinhibited conformation | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Gaubitz, C, Liu, X, Pajak, J, Stone, N, Hayes, J, Demo, G, Kelch, B.A. | Deposit date: | 2022-01-13 | Release date: | 2022-02-16 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader. Elife, 11, 2022
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7TI8
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![BU of 7ti8 by Molmil](/molmil-images/mine/7ti8) | Structure of the yeast clamp loader (Replication Factor C RFC) bound to the open sliding clamp (Proliferating Cell Nuclear Antigen PCNA) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | Authors: | Gaubitz, C, Liu, X, Pajak, J, Stone, N, Hayes, J, Demo, G, Kelch, B.A. | Deposit date: | 2022-01-13 | Release date: | 2022-02-16 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM structures reveal high-resolution mechanism of a DNA polymerase sliding clamp loader. Elife, 11, 2022
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