8PFU
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![BU of 8pfu by Molmil](/molmil-images/mine/8pfu) | X-ray structure of the adduct formed upon reaction of Lysozyme with K3[Ru2(CO3)4] in condition A | Descriptor: | 6,8-bis(4-fluorophenyl)-1,5-bis(oxidanyl)-2,4-dioxa-6,8-diaza-1$l^{4},5$l^{4}-diruthenabicyclo[3.3.0]octan-3-one, CARBONATE ION, Lysozyme C, ... | Authors: | Teran, A, Ferraro, G, Merlino, A. | Deposit date: | 2023-06-16 | Release date: | 2023-07-19 | Method: | X-RAY DIFFRACTION (1.18 Å) | Cite: | Charge effect in protein metalation reactions by diruthenium complexes Inorg Chem Front, 2023
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8PFT
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![BU of 8pft by Molmil](/molmil-images/mine/8pft) | X-ray structure of the adduct formed upon reaction of Lysozyme with K2[Ru2(D-p-FPhF)(CO3)3] in condition A | Descriptor: | 6,8-bis(4-fluorophenyl)-1,5-bis(oxidanyl)-2,4-dioxa-6,8-diaza-1$l^{4},5$l^{4}-diruthenabicyclo[3.3.0]octan-3-one, CHLORIDE ION, Lysozyme C, ... | Authors: | Teran, A, Ferraro, G, Merlino, A. | Deposit date: | 2023-06-16 | Release date: | 2023-07-19 | Method: | X-RAY DIFFRACTION (1.304 Å) | Cite: | Charge effect in protein metalation reactions by diruthenium complexes Inorg Chem Front, 2023
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7P26
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![BU of 7p26 by Molmil](/molmil-images/mine/7p26) | |
8PFW
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![BU of 8pfw by Molmil](/molmil-images/mine/8pfw) | |
7OQR
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![BU of 7oqr by Molmil](/molmil-images/mine/7oqr) | Crystal structure of Trypanosoma cruzi peroxidase | Descriptor: | ACETATE ION, Ascorbate peroxidase, GLYCEROL, ... | Authors: | Freeman, S.L, Kwon, H, Skafar, V, Fielding, A.J, Martinez, A, Piacenza, L, Radi, R, Raven, E.L. | Deposit date: | 2021-06-04 | Release date: | 2022-06-22 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Crystal structure of Trypanosoma cruzi heme peroxidase and characterization of its substrate specificity and compound I intermediate. J.Biol.Chem., 298, 2022
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8PFX
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![BU of 8pfx by Molmil](/molmil-images/mine/8pfx) | X-ray structure of the adduct formed upon reaction of Lysozyme with K2[Ru2(D-p-FPhF)(CO3)3] in condition B | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 6,8-bis(4-fluorophenyl)-1,5-bis(oxidanyl)-2,4-dioxa-6,8-diaza-1$l^{4},5$l^{4}-diruthenabicyclo[3.3.0]octan-3-one, FORMIC ACID, ... | Authors: | Teran, A, Ferraro, G, Merlino, A. | Deposit date: | 2023-06-16 | Release date: | 2023-07-19 | Method: | X-RAY DIFFRACTION (1.03 Å) | Cite: | Charge effect in protein metalation reactions by diruthenium complexes Inorg Chem Front, 2023
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8OT5
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![BU of 8ot5 by Molmil](/molmil-images/mine/8ot5) | Crystal structure of the titin domain Fn3-85 | Descriptor: | CHLORIDE ION, SODIUM ION, Titin | Authors: | Nikoopour, R, Rees, M, Gautel, M. | Deposit date: | 2023-04-20 | Release date: | 2023-08-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Structure determination and analysis of titin A-band fibronectin type III domains provides insights for disease-linked variants and protein oligomerisation. J.Struct.Biol., 215, 2023
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1Q3X
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![BU of 1q3x by Molmil](/molmil-images/mine/1q3x) | Crystal structure of the catalytic region of human MASP-2 | Descriptor: | GLYCEROL, Mannan-binding lectin serine protease 2, SODIUM ION | Authors: | Harmat, V, Gal, P, Kardos, J, Szilagyi, K, Ambrus, G, Naray-Szabo, G, Zavodszky, P. | Deposit date: | 2003-08-01 | Release date: | 2004-08-03 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | The structure of MBL-associated serine protease-2 reveals that identical substrate specificities of C1s and MASP-2 are realized through different sets of enzyme-substrate interactions J.Mol.Biol., 342, 2004
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7OXX
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![BU of 7oxx by Molmil](/molmil-images/mine/7oxx) | CrabP2 mutant R30AK31A | Descriptor: | Cellular retinoic acid-binding protein 2, SODIUM ION | Authors: | Tomlinson, C.W.E, Basle, A, Pohl, E. | Deposit date: | 2021-06-23 | Release date: | 2022-07-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | Structural requirements for the specific binding of CRABP2 to cyclin D3 To Be Published
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8PJM
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7P23
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![BU of 7p23 by Molmil](/molmil-images/mine/7p23) | |
7OL7
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![BU of 7ol7 by Molmil](/molmil-images/mine/7ol7) | |
7P6F
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![BU of 7p6f by Molmil](/molmil-images/mine/7p6f) | 1.93 A resolution X-ray crystal structure of the transcriptional regulator SrnR from Streptomyces griseus | Descriptor: | ACETATE ION, SODIUM ION, Transcriptional regulator SrnR | Authors: | Mazzei, L, Ciurli, S. | Deposit date: | 2021-07-16 | Release date: | 2022-05-25 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Structure, dynamics, and function of SrnR, a transcription factor for nickel-dependent gene expression. Metallomics, 13, 2021
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8H63
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![BU of 8h63 by Molmil](/molmil-images/mine/8h63) | Crystal structure of Internalin A from Listeria monocytogenes with nanobody VHH10 bound | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ISOPROPYL ALCOHOL, ... | Authors: | Caaveiro, J.M.M, Nagatoish, S, Tsumoto, K. | Deposit date: | 2022-10-15 | Release date: | 2023-10-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Anti-InlA single-domain antibodies that inhibit the cell invasion of Listeria monocytogenes. J.Biol.Chem., 299, 2023
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7OL6
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![BU of 7ol6 by Molmil](/molmil-images/mine/7ol6) | |
8OTM
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![BU of 8otm by Molmil](/molmil-images/mine/8otm) | structure of InhA from mycobacterium tuberculosis in complex with N-((1-(3-hydroxy-4-phenoxybenzyl)-1H-1,2,3-triazol-4-yl)methyl)-2-oxo-2H-chromene-3-carboxamide | Descriptor: | 1,2-ETHANEDIOL, 2-oxidanylidene-~{N}-[[1-[(3-oxidanyl-4-phenoxy-phenyl)methyl]-1,2,3-triazol-4-yl]methyl]chromene-3-carboxamide, ACETATE ION, ... | Authors: | Chebaiki, M, Maveyraud, L, Tamhaev, R, Lherbet, C, Mourey, L. | Deposit date: | 2023-04-21 | Release date: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Discovery of new diaryl ether inhibitors against Mycobacterium tuberculosis targeting the minor portal of InhA. Eur.J.Med.Chem., 259, 2023
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7P8P
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![BU of 7p8p by Molmil](/molmil-images/mine/7p8p) | Crystal structure of Fhit covalently bound to a nucleotide | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bis(5'-adenosyl)-triphosphatase, SODIUM ION, ... | Authors: | Herzog, D, Missun, M, Diederichs, K, Marx, A. | Deposit date: | 2021-07-23 | Release date: | 2022-06-01 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | Chemical Proteomics of the Tumor Suppressor Fhit Covalently Bound to the Cofactor Ap 3 A Elucidates Its Inhibitory Action on Translation. J.Am.Chem.Soc., 144, 2022
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8P1T
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![BU of 8p1t by Molmil](/molmil-images/mine/8p1t) | Crystal structure of human methionine adenosyltransferase 2A (MAT2A) in complex with SAM and allosteric inhibitor Z237451470 | Descriptor: | 1,2-ETHANEDIOL, 6-cyclopropyl-~{N}-(1~{H}-indazol-5-yl)-1-propan-2-yl-pyrazolo[3,4-b]pyridine-4-carboxamide, CHLORIDE ION, ... | Authors: | Thomsen, M, Thieulin-Pardo, G, Neumann, L. | Deposit date: | 2023-05-12 | Release date: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.442 Å) | Cite: | Discovery of novel methionine adenosyltransferase 2A (MAT2A) allosteric inhibitors by structure-based virtual screening. Bioorg.Med.Chem.Lett., 94, 2023
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7OPH
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![BU of 7oph by Molmil](/molmil-images/mine/7oph) | NaK S-DI mutant with Na+ and K+ | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ... | Authors: | Minniberger, S, Plested, A.J.R. | Deposit date: | 2021-05-31 | Release date: | 2022-06-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Asymmetry and Ion Selectivity Properties of Bacterial Channel NaK Mutants Derived from Ionotropic Glutamate Receptors. J.Mol.Biol., 435, 2023
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7OPT
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![BU of 7opt by Molmil](/molmil-images/mine/7opt) | Crystal structure of Trypanosoma cruzi peroxidase | Descriptor: | Ascorbate peroxidase, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Freeman, S.L, Kwon, H, Skafar, V, Fielding, A.J, Martinez, A, Piacenza, L, Radi, R, Raven, E.L. | Deposit date: | 2021-06-01 | Release date: | 2022-06-08 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Crystal structure of Trypanosoma cruzi heme peroxidase and characterization of its substrate specificity and compound I intermediate. J.Biol.Chem., 298, 2022
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7OOK
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![BU of 7ook by Molmil](/molmil-images/mine/7ook) | Bacteriophage PRD1 Major Capsid Protein P3 in complex with CPZ | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine, CHLORIDE ION, ... | Authors: | Duyvesteyn, H.M.E, Peccati, F, Martinez-Castillo, A, Jimenez-Oses, G, Oksanen, H.M, Stuart, D.I, Abrescia, N.G.A. | Deposit date: | 2021-05-27 | Release date: | 2022-06-08 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Bacteriophage PRD1 as a nanoscaffold for drug loading Nanoscale, 13, 2021
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8PH7
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![BU of 8ph7 by Molmil](/molmil-images/mine/8ph7) | X-ray structure of the adduct formed upon reaction of Lysozyme with [Ru2Cl(DPhF)(O2CCH3)3] in condition A | Descriptor: | Lysozyme C, SODIUM ION, SUCCINIC ACID, ... | Authors: | Teran, A, Ferraro, G, Merlino, A. | Deposit date: | 2023-06-19 | Release date: | 2023-09-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.406 Å) | Cite: | Steric hindrance and charge influence on the cytotoxic activity and protein binding properties of diruthenium complexes. Int.J.Biol.Macromol., 253, 2023
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8P0Z
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![BU of 8p0z by Molmil](/molmil-images/mine/8p0z) | AP01-S2.3 - a variant of a redesigned transferrin receptor apical domain | Descriptor: | BORIC ACID, SODIUM ION, Transferrin receptor protein 1, ... | Authors: | Oberdorfer, G, Grill, B, Bjelic, S, Stoll, D. | Deposit date: | 2023-05-11 | Release date: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Affinity Maturated Transferrin Receptor Apical Domain Blocks Machupo Virus Glycoprotein Binding. J.Mol.Biol., 435, 2023
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8HCG
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![BU of 8hcg by Molmil](/molmil-images/mine/8hcg) | Crystal structure of mTREX1-dAMP complex | Descriptor: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ... | Authors: | Hsiao, Y.Y, Huang, K.W, Wu, C.Y. | Deposit date: | 2022-11-01 | Release date: | 2023-11-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.799 Å) | Cite: | Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids. Nucleic Acids Res., 51, 2023
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8PH8
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![BU of 8ph8 by Molmil](/molmil-images/mine/8ph8) | X-ray structure of the adduct formed upon reaction of Lysozyme with [Ru2Cl(DPhF)2(O2CCH3)2] in condition A | Descriptor: | 1-oxidanyl-2,4,6,8-tetraphenyl-2,4,6,8-tetraza-1$l^{4},5$l^{3}-diruthenabicyclo[3.3.0]octane, Lysozyme C, SODIUM ION, ... | Authors: | Teran, A, Ferraro, G, Merlino, A. | Deposit date: | 2023-06-19 | Release date: | 2023-09-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.29 Å) | Cite: | Steric hindrance and charge influence on the cytotoxic activity and protein binding properties of diruthenium complexes. Int.J.Biol.Macromol., 253, 2023
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