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3S4X	Crystal structure of the Asn152Gly mutant of P99 beta-lactamase Descriptor: Beta-lactamase, SULFATE ION Authors: Ruble, J.F, Powers, R.A. Deposit date: 2011-05-20 Release date: 2012-08-01 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structural analysis of the Asn152Gly mutant of P99 cephalosporinase. Acta Crystallogr.,Sect.D, 68, 2012
5D8N	Tomato leucine aminopeptidase mutant - K354E Descriptor: 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... Authors: DuPrez, K.T, Scranton, M.A, Walling, L.L, Fan, L. Deposit date: 2015-08-17 Release date: 2016-05-11 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Structural insights into chaperone-activity enhancement by a K354E mutation in tomato acidic leucine aminopeptidase. Acta Crystallogr D Struct Biol, 72, 2016
2H7S	L244A mutant of Cytochrome P450cam Descriptor: Cytochrome P450-cam, HEME C Authors: Verras, A, Alian, A, Montellano, P.R. Deposit date: 2006-06-02 Release date: 2006-10-31 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Cytochrome P450 active site plasticity: attenuation of imidazole binding in cytochrome P450cam by an L244A mutation. Protein Eng.Des.Sel., 19, 2006
1JAW	AMINOPEPTIDASE P FROM E. COLI LOW PH FORM Descriptor: ACETATE ION, AMINOPEPTIDASE P, MANGANESE (II) ION Authors: Wilce, M.C.J, Bond, C.S, Lilley, P.E, Dixon, N.E, Freeman, H.C, Guss, J.M. Deposit date: 1997-12-22 Release date: 1999-04-06 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structure and mechanism of a proline-specific aminopeptidase from Escherichia coli. Proc.Natl.Acad.Sci.USA, 95, 1998
4XN2	Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-Leucine Descriptor: Aminopeptidase N, GLYCEROL, LEUCINE, ... Authors: Addlagatta, A, Gumpena, R. Deposit date: 2015-01-15 Release date: 2016-03-02 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.11 Å) Cite: Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-Leucine To Be Published
4XN7	Crystal Structure of E. coli Aminopeptidase N in complex with L-2,3-Diaminopropionic acid Descriptor: Aminopeptidase N, DIAMINOPROPANOIC ACID, GLYCEROL, ... Authors: Addlagatta, A, Gumpena, R. Deposit date: 2015-01-15 Release date: 2016-03-02 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.22 Å) Cite: Crystal Structure of E. coli Aminopeptidase N in complex with L-2,3-Diaminopropionic acid To Be Published
5Y1H	Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(2,4-difluorobenzyl)ureido)-N-hydroxy-4-methylpentanamide Descriptor: (2R)-2-[[2,4-bis(fluoranyl)phenyl]methylcarbamoylamino]-4-methyl-N-oxidanyl-pentanamide, GLYCEROL, M1 family aminopeptidase, ... Authors: Marapaka, A.K, Zhang, Y, Addlagatta, A. Deposit date: 2017-07-20 Release date: 2018-08-01 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.73 Å) Cite: Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(2,4-difluorobenzyl)ureido)-N-hydroxy-4-methylpentanamide To Be Published
4XN4	Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-Methionine Descriptor: Aminopeptidase N, GLYCEROL, MALONATE ION, ... Authors: Addlagatta, A, Gumpena, R. Deposit date: 2015-01-15 Release date: 2016-03-02 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-Methionine To Be Published
5Y1K	Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(2-chlorobenzyl)ureido)-N-hydroxy-4-methylpentanamide Descriptor: (2S)-2-[(2-chlorophenyl)methylcarbamoylamino]-4-methyl-N-oxidanyl-pentanamide, GLYCEROL, M1 family aminopeptidase, ... Authors: Marapaka, A.K, Zhang, Y, Addlagatta, A. Deposit date: 2017-07-20 Release date: 2018-08-01 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.81 Å) Cite: Development of peptidomimetic hydroxamates as PfA-M1 and PfA-M17 dual inhibitors: Biological evaluation and structural characterization by cocrystallization Chin.Chem.Lett., 33, 2022
5Y3I	Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-N-hydroxy-4-methyl-2-(3-(3-methylbenzyl)ureido)pentanamide Descriptor: (2R)-4-methyl-2-[(3-methylphenyl)methylcarbamoylamino]-N-oxidanyl-pentanamide, GLYCEROL, M1 family aminopeptidase, ... Authors: Marapaka, A.K, Zhang, Y, Addlagatta, A. Deposit date: 2017-07-28 Release date: 2018-08-08 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.73 Å) Cite: Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-N-hydroxy-4-methyl-2-(3-(3-methylbenzyl)ureido)pentanamide To Be Published
4XND	Crystal Structure of E. coli Aminopeptidase N in complex with L-Beta Homotryptophan Descriptor: (3S)-3-AMINO-4-(1H-INDOL-3-YL)BUTANOIC ACID, Aminopeptidase N, GLYCEROL, ... Authors: Addlagatta, A, Gumpena, R. Deposit date: 2015-01-15 Release date: 2016-03-02 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Crystal Structure of E. coli Aminopeptidase N in complex with L-Beta Homotryptophan To Be Published
5Y1S	Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(3,4-dimethylbenzyl)ureido)-N-hydroxy-4-methylpentanamide Descriptor: (2R)-2-[(3,4-dimethylphenyl)methylcarbamoylamino]-4-methyl-N-oxidanyl-pentanamide, (2S)-2-[(3,4-dimethylphenyl)methylcarbamoylamino]-4-methyl-N-oxidanyl-pentanamide, GLYCEROL, ... Authors: Marapaka, A.K, Zhang, Y, Addlagatta, A. Deposit date: 2017-07-21 Release date: 2018-08-01 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.66 Å) Cite: Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(3,4-dimethylbenzyl)ureido)-N-hydroxy-4-methylpentanamide To Be Published
5Y1Q	Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(3-chlorobenzyl)ureido)-N-hydroxy-4-methylpentanamide Descriptor: (2S)-2-[(3-chlorophenyl)methylcarbamoylamino]-4-methyl-N-oxidanyl-pentanamide, M1 family aminopeptidase, MAGNESIUM ION, ... Authors: Marapaka, A.K, Zhang, Y, Addlagatta, A. Deposit date: 2017-07-21 Release date: 2018-08-01 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.14 Å) Cite: Development of peptidomimetic hydroxamates as PfA-M1 and PfA-M17 dual inhibitors: Biological evaluation and structural characterization by cocrystallization Chin.Chem.Lett., 33, 2022
4XMU	Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-Alanine Descriptor: ALANINE, Aminopeptidase N, GLYCEROL, ... Authors: Addlagatta, A, Gumpena, R, Kishor, C. Deposit date: 2015-01-15 Release date: 2016-03-02 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.91 Å) Cite: Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N To Be Published
4XMZ	Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with 2,4-diaminobutyric acid Descriptor: 2,4-DIAMINOBUTYRIC ACID, Aminopeptidase N, GLYCEROL, ... Authors: Addlagatta, A, Gumpena, R. Deposit date: 2015-01-15 Release date: 2016-01-27 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with 2,4-diaminobutyric acid To Be Published
4XN9	Crystal Structure of E. coli Aminopeptidase N in complex with Beta Alanine Descriptor: Aminopeptidase N, BETA-ALANINE, MALONATE ION, ... Authors: Addlagatta, A, Gumpena, R. Deposit date: 2015-01-15 Release date: 2016-03-02 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystal Structure of E. coli Aminopeptidase N in complex with Beta Alanine To Be Published
5YQB	Crystal structure of E.coli aminopeptidase N in complex with Puromycin Descriptor: (2R,3R,4S,5S)-4-AMINO-2-[6-(DIMETHYLAMINO)-9H-PURIN-9-YL]-5-(HYDROXYMETHYL)TETRAHYDRO-3-FURANOL, Aminopeptidase N, GLYCEROL, ... Authors: Marapaka, A.K, Ganji, R.J, Reddi, R, Addlagatta, A. Deposit date: 2017-11-06 Release date: 2018-11-14 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.56 Å) Cite: Puromycin, a selective inhibitor of PSA acts as a substrate for other M1 family aminopeptidases: Biochemical and structural basis Int.J.Biol.Macromol., 165, 2020
5Y1V	Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(2,6-diethylphenyl)ureido)- N-hydroxy-4-methylpentanamide Descriptor: (2R)-2-[(2,6-diethylphenyl)carbamoylamino]-4-methyl-N-oxidanyl-pentanamide, GLYCEROL, M1 family aminopeptidase, ... Authors: Marapaka, A.K, Zhang, Y, Addlagatta, A. Deposit date: 2017-07-21 Release date: 2018-08-01 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.62 Å) Cite: Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-(3-(2,6-diethylphenyl)ureido)- N-hydroxy-4-methylpentanamide To Be Published
4XMT	Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-2,3-Diaminopropionic acid Descriptor: Aminopeptidase N, DIAMINOPROPANOIC ACID, GLYCEROL, ... Authors: Addlagatta, A, Gumpena, R. Deposit date: 2015-01-15 Release date: 2016-03-02 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-2,3-Diaminopropionic acid To Be Published
4XNA	Crystal Structure of E. coli Aminopeptidase N in complex with L-Beta Homolysine Descriptor: (3S)-3,7-DIAMINOHEPTANOIC ACID, Aminopeptidase N, GLYCEROL, ... Authors: Addlagatta, A, Gumpena, R. Deposit date: 2015-01-15 Release date: 2016-03-02 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Crystal Structure of E. coli Aminopeptidase N in complex with L-Beta Homolysin To Be Published
4XO3	Crystal Structure of E. coli Aminopeptidase N in complex with L-Leucine Descriptor: Aminopeptidase N, GLYCEROL, LEUCINE, ... Authors: Addlagatta, A, Gumpena, R. Deposit date: 2015-01-16 Release date: 2016-01-27 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal Structure of E. coli Aminopeptidase N in complex with L-Leucine To Be Published
4XMX	Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with Bestatin Descriptor: 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, Aminopeptidase N, GLYCEROL, ... Authors: Addlagatta, A, Gumpena, R, Kishor, C. Deposit date: 2015-01-15 Release date: 2016-02-10 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with Bestatin To Be Published
4XN5	Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-Phenylalanine Descriptor: Aminopeptidase N, GLYCEROL, MALONATE ION, ... Authors: Addlagatta, A, Gumpena, R, Kishor, C. Deposit date: 2015-01-15 Release date: 2016-02-10 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.66 Å) Cite: Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-Phenylalanine To Be Published
5YO1	Structure of ePepN E298A mutant in complex with Puromycin Descriptor: Aminopeptidase N, GLYCEROL, PUROMYCIN, ... Authors: Ganji, R.J, Reddi, R, Marapaka, A.K, Addlagatta, A. Deposit date: 2017-10-26 Release date: 2018-11-07 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Puromycin, a selective inhibitor of PSA acts as a substrate for other M1 family aminopeptidases: Biochemical and structural basis Int.J.Biol.Macromol., 165, 2020
5Y19	Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-((2S,3R)-3-amino-2-hydroxy-4-phenylbutanamido)- N-hydroxy-4-methylpentanamide. Descriptor: (2S)-2-[[(2S,3R)-3-azanyl-2-oxidanyl-4-phenyl-butanoyl]amino]-4-methyl-N-oxidanyl-pentanamide, GLYCEROL, M1 family aminopeptidase, ... Authors: Marapaka, A.K, Zhang, Y, Addlagatta, A. Deposit date: 2017-07-19 Release date: 2018-08-01 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.83 Å) Cite: Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-((2S,3R)-3-amino-2-hydroxy-4-phenylbutanamido)- N-hydroxy-4-methylpentanamide. To Be Published

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