PDB: 222415 resultsInfo pagesStatus searchChemie searchBIRD

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3COP	Crystal Structure of E.coli GS mutant E377A in complex with ADP and acceptor analogue HEPPSO Descriptor: (2R)-2-hydroxy-3-[4-(2-hydroxyethyl)piperazin-1-yl]propane-1-sulfonic acid, ADENOSINE-5'-DIPHOSPHATE, Glycogen synthase, ... Authors: Sheng, F, Geiger, J.H. Deposit date: 2008-03-28 Release date: 2009-03-24 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The Crystal Structures of the Open and Catalytically Competent Closed Conformation of Escherichia coli Glycogen Synthase. J.Biol.Chem., 284, 2009
3CPF	Crystal structure of human eukaryotic translation initiation factor EIF5A Descriptor: Eukaryotic translation initiation factor 5A-1, UNKNOWN ATOM OR ION Authors: Nedyalkova, L, Tong, Y, Tempel, W, Hong, B, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) Deposit date: 2008-03-31 Release date: 2008-04-15 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structure of human eIF5A1: insight into functional similarity of human eIF5A1 and eIF5A2. Proteins, 75, 2009
3CLC	Crystal Structure of the Restriction-Modification Controller Protein C.Esp1396I Tetramer in Complex with its Natural 35 Base-Pair Operator Descriptor: 35-MER, MAGNESIUM ION, Regulatory protein Authors: McGeehan, J.E, Streeter, S.D, Thresh, S.J, Ball, N, Ravelli, R.B, Kneale, G.G. Deposit date: 2008-03-18 Release date: 2008-07-29 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structural analysis of the genetic switch that regulates the expression of restriction-modification genes. Nucleic Acids Res., 36, 2008
3H8O	Structure determination of DNA methylation lesions N1-meA and N3-meC in duplex DNA using a cross-linked host-guest system Descriptor: 5'-D(*CP*TP*GP*TP*AP*TP*(2YR)P*AP*TP*(MA7)P*GP*CP*G)-3', 5'-D(*TP*CP*GP*CP*TP*AP*TP*AP*AP*TP*AP*CP*A)-3', Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2, ... Authors: Lu, L, Yi, C, Jian, X, Zheng, Q. Deposit date: 2009-04-29 Release date: 2010-03-31 Last modified: 2021-10-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure determination of DNA methylation lesions N1-meA and N3-meC in duplex DNA using a cross-linked protein-DNA system. Nucleic Acids Res., 38, 2010
3GJX	Crystal Structure of the Nuclear Export Complex CRM1-Snurportin1-RanGTP Descriptor: CHLORIDE ION, Exportin-1, GTP-binding nuclear protein Ran, ... Authors: Monecke, T, Guettler, T, Neumann, P, Dickmanns, A, Goerlich, D, Ficner, R. Deposit date: 2009-03-09 Release date: 2009-05-26 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal Structure of the Nuclear Export Receptor CRM1 in Complex with Snurportin1 and RanGTP. Science, 2009
3GMX	Crystal Structure of Beta-Lactamse Inhibitory Protein-Like Protein (BLP) at 1.05 Angstrom Resolution Descriptor: ACETATE ION, BLP Authors: Gretes, M, Strynadka, N.C.J. Deposit date: 2009-03-15 Release date: 2009-03-31 Last modified: 2017-11-01 Method: X-RAY DIFFRACTION (1.05 Å) Cite: Insights into positive and negative requirements for protein-protein interactions by crystallographic analysis of the beta-lactamase inhibitory proteins BLIP, BLIP-I, and BLP. J.Mol.Biol., 389, 2009
3GQ7	Crystal Structure of the Bacteriophage Phi29 Gene Product 12 N-terminal Fragment Descriptor: CALCIUM ION, CARBONATE ION, MAGNESIUM ION, ... Authors: Xiang, Y, Rossmann, M.G. Deposit date: 2009-03-24 Release date: 2009-05-26 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Crystallographic insights into the autocatalytic assembly mechanism of a bacteriophage tail spike. Mol.Cell, 34, 2009
3GSG	AmpC beta-lactamase in complex with Fragment-based Inhibitor Descriptor: (2S)-2-[(3aR,4R,7S,7aS)-1,3-dioxooctahydro-2H-4,7-methanoisoindol-2-yl]propanoic acid, Beta-lactamase, DIMETHYL SULFOXIDE, ... Authors: Teotico, D.T, Shoichet, B.K. Deposit date: 2009-03-26 Release date: 2009-04-14 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Docking for fragment inhibitors of AmpC beta-lactamase Proc.Natl.Acad.Sci.USA, 106, 2009
3GRJ	AmpC beta-lactamase in complex with Fragment-based Inhibitor Descriptor: 2-phenyl-1H-imidazole-4-carboxylic acid, Beta-lactamase, DI(HYDROXYETHYL)ETHER, ... Authors: Teotico, D.T, Shoichet, B.K. Deposit date: 2009-03-25 Release date: 2009-04-14 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.49 Å) Cite: Docking for fragment inhibitors of AmpC beta-lactamase Proc.Natl.Acad.Sci.USA, 106, 2009
3GSX	Crystal structure of the binary complex between HLA-A2 and HCMV NLV-T8V peptide variant Descriptor: Beta-2-microglobulin, HCMV pp65 fragment 495-503, variant T8V (NLVPMVAVV), ... Authors: Reiser, J.-B, Saulquin, X, Gras, S, Debeaupuis, E, Echasserieau, K, Kissenpfennig, A, Legoux, F, Chouquet, A, Le Gorrec, M, Machillot, P, Neveu, B, Thielens, N, Malissen, B, Bonneville, M, Housset, D. Deposit date: 2009-03-27 Release date: 2009-08-04 Last modified: 2021-10-13 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structural bases for the affinity-driven selection of a public TCR against a dominant human cytomegalovirus epitope. J.Immunol., 183, 2009
3GTY	Promiscuous Substrate Recognition in Folding and Assembly Activities of the Trigger Factor Chaperone Descriptor: 30S ribosomal protein S7, Trigger factor Authors: Martinez-Hackert, E, Hendrickson, W.A. Deposit date: 2009-03-28 Release date: 2009-12-22 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Promiscuous substrate recognition in folding and assembly activities of the trigger factor chaperone Cell(Cambridge,Mass.), 138, 2009
3GZ4	Crystal structure of putative short chain dehydrogenase FROM ESCHERICHIA COLI CFT073 complexed with NADPH Descriptor: Hypothetical oxidoreductase yciK, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Malashkevich, V.N, Toro, R, Morano, C, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) Deposit date: 2009-04-06 Release date: 2009-04-14 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Crystal structure of putative short chain dehydrogenase FROM ESCHERICHIA COLI CFT073 complexed with NADPH To be Published
3GVC	Crystal structure of probable short-chain dehydrogenase-reductase from Mycobacterium tuberculosis Descriptor: Probable short-chain type dehydrogenase/reductase Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2009-03-30 Release date: 2009-04-07 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3H1P	Mature Caspase-7 I213A with DEVD-CHO inhibitor bound to active site Descriptor: Caspase-7, N-ACETYL-L-ALPHA-ASPARTYL-L-ALPHA-GLUTAMYL-N-[(2S)-1-CARBOXY-3-HYDROXYPROPAN-2-YL]-L-VALINAMIDE Authors: Witkowski, W.A, Hardy, J.A. Deposit date: 2009-04-13 Release date: 2009-06-30 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.61 Å) Cite: L2' loop is critical for caspase-7 active site formation. Protein Sci., 18, 2009
3H12	Crystal structure of putative mandelate racemase from Bordetella Bronchiseptica RB50 Descriptor: SODIUM ION, mandelate racemase Authors: Malashkevich, V.N, Toro, R, Morano, C, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) Deposit date: 2009-04-10 Release date: 2009-04-21 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Crystal structure of putative mandelate racemase from Bordetella Bronchiseptica RB50 To be Published
3H3S	Crystal structure of the CERT START domain in complex with HPA-15 Descriptor: Goodpasture antigen binding protein, N-[(1R,3R)-3-hydroxy-1-(hydroxymethyl)-3-phenylpropyl]pentadecanamide Authors: Kudo, N, Wakatsuki, S, Kato, R. Deposit date: 2009-04-17 Release date: 2010-03-02 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.66 Å) Cite: Crystal structures of the CERT START domain with inhibitors provide insights into the mechanism of ceramide transfer. J.Mol.Biol., 396, 2010
3H5G	Switching the Chirality of the Metal Environment Alters the Coordination Mode in Designed Peptides. Descriptor: ACETATE ION, COIL SER L16D-Pen, ZINC ION Authors: Peacock, A.F.A, Stuckey, J.A, Pecoraro, V.L. Deposit date: 2009-04-22 Release date: 2009-07-14 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.71 Å) Cite: Switching the Chirality of the Metal Environment Alters the Coordination Mode in Designed Peptides. Angew.Chem.Int.Ed.Engl., 48, 2009
3H9S	The complex between TCR A6 and human Class I MHC HLA-A2 with the bound Tel1p peptide Descriptor: A6 TCR alpha chain, Beta-2-microglobulin, GLYCEROL, ... Authors: Borbulevych, O.Y, Baker, B.M. Deposit date: 2009-04-30 Release date: 2010-01-12 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.7 Å) Cite: T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility. Immunity, 31, 2009
3GP0	Crystal Structure of Human Mitogen Activated Protein Kinase 11 (p38 beta) in complex with Nilotinib Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Mitogen-activated protein kinase 11, ... Authors: Filippakopoulos, P, Barr, A, Fedorov, O, Keates, T, Soundararajan, M, Elkins, J, Salah, E, Burgess-Brown, N, Ugochukwu, E, Pike, A.C.W, Muniz, J, Roos, A, Chaikuad, A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2009-03-20 Release date: 2009-04-07 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal Structure of Human Mitogen Activated Protein Kinase 11 (p38 beta) in complex with Nilotinib To be Published
3ETQ	X-ray structure of cysteine-free fragment of mHCN2 C-terminal region from amino acids 443-630 including C508N, C584S, and C601S mutations Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 Authors: Flynn, G.E. Deposit date: 2008-10-08 Release date: 2009-06-23 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Mapping the structure and conformational movements of proteins with transition metal ion FRET. Nat.Methods, 6, 2009
3ETY	Crystal structure of bacterial adhesin FadA L14A mutant Descriptor: Adhesin A Authors: Nithianantham, S, Xu, M, Wu, N, Shoham, M, Han, Y.W. Deposit date: 2008-10-08 Release date: 2008-12-02 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Crystal Structure of FadA Adhesin from Fusobacterium nucleatum Reveals a Novel Oligomerization Motif, the Leucine Chain. J.Biol.Chem., 284, 2009
3EVQ	Crystal structure of Staphylococcal nuclease variant Delta+PHS L25E at cryogenic temperature Descriptor: CALCIUM ION, THYMIDINE-3',5'-DIPHOSPHATE, Thermonuclease Authors: Robinson, A.C, Schlessman, J.L, Garcia-Moreno, E.B. Deposit date: 2008-10-13 Release date: 2008-11-04 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal Structure of D+PHS L25E at cryogenic temperature To be Published
3EN4	Targeted polypharmacology: crystal structure of the c-Src kinase domain in complex with PP121, a multitargeted kinase inhibitor Descriptor: 1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Proto-oncogene tyrosine-protein kinase Src Authors: Blair, J.A, Apsel, B, Knight, Z.A, Shokat, K.M. Deposit date: 2008-09-25 Release date: 2008-10-14 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.55 Å) Cite: Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases. Nat.Chem.Biol., 4, 2008
3E6H	MHC CLASS I H-2Dd heavy chain complexed with Beta-2 Microglobulin and a variant peptide, PI10, from the human immunodeficiency virus (BaL) envelope glycoprotein 120 Descriptor: Envelope glycoprotein 10-residue peptide, H-2 class I histocompatibility antigen, D-D alpha chain, ... Authors: Wang, R, Natarajan, K, Robinson, H, Margulies, D.H. Deposit date: 2008-08-15 Release date: 2009-08-18 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Different vaccine vectors delivering the same antigen elicit CD8+ T cell responses with distinct clonotype and epitope specificity J.Immunol., 183, 2009
3ETI	Structure of a cubic crystal form of X (ADRP) domain from FCoV Descriptor: macro domain of Non-structural protein 3 Authors: Wojdyla, J.A, Manolaridis, I, Tucker, P.A. Deposit date: 2008-10-08 Release date: 2009-10-13 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structure of the X (ADRP) domain of nsp3 from feline coronavirus Acta Crystallogr.,Sect.D, 65, 2009

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