3F3V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3f3v by Molmil](/molmil-images/mine/3f3v) | Kinase domain of cSrc in complex with inhibitor RL45 (Type II) | Descriptor: | 1-{4-[(6-aminoquinazolin-4-yl)amino]phenyl}-3-[3-tert-butyl-1-(3-methylphenyl)-1H-pyrazol-5-yl]urea, Proto-oncogene tyrosine-protein kinase Src | Authors: | Grutter, C, Kluter, S, Getlik, M, Rauh, D. | Deposit date: | 2008-10-31 | Release date: | 2009-06-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Hybrid compound design to overcome the gatekeeper T338M mutation in cSrc J.Med.Chem., 52, 2009
|
|
4R65
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4r65 by Molmil](/molmil-images/mine/4r65) | Ternary complex crystal structure of R258A mutant of DNA polymerase Beta | Descriptor: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), ... | Authors: | Batra, V.K, Beard, W.A, Wilson, S.H. | Deposit date: | 2014-08-22 | Release date: | 2014-10-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Substrate-induced DNA Polymerase beta Activation. J.Biol.Chem., 289, 2014
|
|
3EY9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ey9 by Molmil](/molmil-images/mine/3ey9) | Structural basis for membrane binding and catalytic activation of the peripheral membrane enzyme pyruvate oxidase from Escherichia coli | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, Pyruvate dehydrogenase [cytochrome], ... | Authors: | Neumann, P, Weidner, A, Pech, A, Stubbs, M.T, Tittmann, K. | Deposit date: | 2008-10-20 | Release date: | 2008-11-04 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural basis for membrane binding and catalytic activation of the peripheral membrane enzyme pyruvate oxidase from Escherichia coli. Proc.Natl.Acad.Sci.USA, 105, 2008
|
|
3W8M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3w8m by Molmil](/molmil-images/mine/3w8m) | Crystal Structure of HasAp with Iron Salophen | Descriptor: | 2,2'-[1,2-PHENYLENEBIS(NITRILOMETHYLIDYNE)]BIS[PHENOLATO]](2-)-N,N',O,O']-IRON, Heme acquisition protein HasAp | Authors: | Shirataki, C, Shoji, O, Sugimoto, H, Shiro, Y, Watanabe, Y. | Deposit date: | 2013-03-19 | Release date: | 2014-01-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.46 Å) | Cite: | Inhibition of Heme Uptake in Pseudomonas aeruginosa by its Hemophore (HasAp ) Bound to Synthetic Metal Complexes Angew.Chem.Int.Ed.Engl., 53, 2014
|
|
3WBK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3wbk by Molmil](/molmil-images/mine/3wbk) | crystal structure analysis of eukaryotic translation initiation factor 5B and 1A complex | Descriptor: | Eukaryotic translation initiation factor 1A, Eukaryotic translation initiation factor 5B | Authors: | Zheng, A, Yamamoto, R, Ose, T, Yu, J, Tanaka, I, Yao, M. | Deposit date: | 2013-05-20 | Release date: | 2014-11-19 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | X-ray structures of eIF5B and the eIF5B-eIF1A complex: the conformational flexibility of eIF5B is restricted on the ribosome by interaction with eIF1A Acta Crystallogr.,Sect.D, 70, 2014
|
|
3CTP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ctp by Molmil](/molmil-images/mine/3ctp) | Crystal structure of periplasmic binding protein/LacI transcriptional regulator from Alkaliphilus metalliredigens QYMF complexed with D-xylulofuranose | Descriptor: | Periplasmic binding protein/LacI transcriptional regulator, SODIUM ION, beta-D-xylulofuranose | Authors: | Malashkevich, V.N, Toro, R, Wasserman, S.R, Meyer, A, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2008-04-14 | Release date: | 2008-05-06 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.41 Å) | Cite: | Crystal structure of periplasmic binding protein/LacI transcriptional regulator from Alkaliphilus metalliredigens QYMF complexed with L-xylulose. To be Published
|
|
3CPS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3cps by Molmil](/molmil-images/mine/3cps) | Crystal structure of Cryptosporidium parvum glyceraldehyde-3-phosphate dehydrogenase | Descriptor: | Glyceraldehyde 3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Wernimont, A.K, Lew, J, Kozieradzki, I, Cossar, D, Schapiro, M, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Hui, R, Pizarro, J, Hills, T, Structural Genomics Consortium (SGC) | Deposit date: | 2008-04-01 | Release date: | 2008-04-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of Cryptosporidium parvum glyceraldehyde-3-phosphate dehydrogenase. To be Published
|
|
4R63
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4r63 by Molmil](/molmil-images/mine/4r63) | Binary complex crystal structure of R258A mutant of DNA polymerase Beta | Descriptor: | DNA (5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... | Authors: | Batra, V.K, Beard, W.A, Wilson, S.H. | Deposit date: | 2014-08-22 | Release date: | 2014-10-08 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Substrate-induced DNA Polymerase beta Activation. J.Biol.Chem., 289, 2014
|
|
3CZT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3czt by Molmil](/molmil-images/mine/3czt) | Crystal Structure of S100B in the Calcium and Zinc Loaded State at pH 9 | Descriptor: | CALCIUM ION, Protein S100-B, ZINC ION | Authors: | Ostendorp, T, Diez, J, Heizmann, C.W, Fritz, G. | Deposit date: | 2008-04-30 | Release date: | 2009-04-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | The crystal structures of human S100B in the zinc- and calcium-loaded state at three pH values reveal zinc ligand swapping. Biochim.Biophys.Acta, 1813, 2011
|
|
4R91
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4r91 by Molmil](/molmil-images/mine/4r91) | BACE-1 in complex with (R)-4-(2-cyclohexylethyl)-4-(((1S,3R)-3-(cyclopentylamino)cyclohexyl)methyl)-1-methyl-5-oxoimidazolidin-2-iminium | Descriptor: | (2E,5R)-5-(2-cyclohexylethyl)-5-{[(1S,3R)-3-(cyclopentylamino)cyclohexyl]methyl}-2-imino-3-methylimidazolidin-4-one, Beta-secretase 1, L(+)-TARTARIC ACID | Authors: | Orth, P, Caldwell, J.P, Strickland, C. | Deposit date: | 2014-09-03 | Release date: | 2014-11-05 | Last modified: | 2014-12-17 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Discovery of potent iminoheterocycle BACE1 inhibitors. Bioorg.Med.Chem.Lett., 24, 2014
|
|
3D0O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3d0o by Molmil](/molmil-images/mine/3d0o) | |
3D0Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3d0y by Molmil](/molmil-images/mine/3d0y) | Crystal Structure of S100B in the Calcium and Zinc Loaded State at pH 6.5 | Descriptor: | CALCIUM ION, Protein S100-B, TETRAETHYLENE GLYCOL, ... | Authors: | Ostendorp, T, Diez, J, Heizmann, C.W, Fritz, G. | Deposit date: | 2008-05-02 | Release date: | 2009-04-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The crystal structures of human S100B in the zinc- and calcium-loaded state at three pH values reveal zinc ligand swapping. Biochim.Biophys.Acta, 1813, 2011
|
|
3CR6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3cr6 by Molmil](/molmil-images/mine/3cr6) | |
4R9N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4r9n by Molmil](/molmil-images/mine/4r9n) | |
3CRK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3crk by Molmil](/molmil-images/mine/3crk) | Crystal structure of the PDHK2-L2 complex. | Descriptor: | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial, POTASSIUM ION, ... | Authors: | Green, T.J, Popov, K.M, Luo, M, Grigorian, A, Klyuyeva, A, Tuganova, A. | Deposit date: | 2008-04-07 | Release date: | 2008-04-29 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural and functional insights into the molecular mechanisms responsible for the regulation of pyruvate dehydrogenase kinase 2. J.Biol.Chem., 283, 2008
|
|
3D2B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3d2b by Molmil](/molmil-images/mine/3d2b) | |
3WS6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ws6 by Molmil](/molmil-images/mine/3ws6) | Crystal Structure of H-2D in complex with a mimotopic peptide | Descriptor: | Beta-2-microglobulin, GLYCEROL, H-2 class I histocompatibility antigen, ... | Authors: | Kumar, P.R, Mukherjee, G, Samanta, D, DiLorenzo, T.P, Almo, S.C, Immune Function Network, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2014-02-28 | Release date: | 2014-03-26 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Compensatory mechanisms allow undersized anchor-deficient class I MHC ligands to mediate pathogenic autoreactive T cell responses J. Immunol., 193, 2014
|
|
3CT6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ct6 by Molmil](/molmil-images/mine/3ct6) | Crystal structure of DhaM of L. lactis | Descriptor: | PTS-dependent dihydroxyacetone kinase, phosphotransferase subunit dhaM | Authors: | Zurbriggen, A. | Deposit date: | 2008-04-11 | Release date: | 2008-10-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | X-ray Structures of the Three Lactococcus lactis Dihydroxyacetone Kinase Subunits and of a Transient Intersubunit Complex. J.Biol.Chem., 283, 2008
|
|
4RG4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4rg4 by Molmil](/molmil-images/mine/4rg4) | |
3D5S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3d5s by Molmil](/molmil-images/mine/3d5s) | Crystal Structure of Efb-C (R131A) / C3d Complex | Descriptor: | Complement C3, Fibrinogen-binding protein | Authors: | Geisbrecht, B.V. | Deposit date: | 2008-05-16 | Release date: | 2008-09-16 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Electrostatic contributions drive the interaction between Staphylococcus aureus protein Efb-C and its complement target C3d. Protein Sci., 17, 2008
|
|
4RDN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4rdn by Molmil](/molmil-images/mine/4rdn) | Structure of YTH-YTHDF2 in complex with m6A | Descriptor: | N-methyladenosine, SULFATE ION, YTH domain-containing family protein 2 | Authors: | Li, F.D, Zhao, D.B, Wu, J.H, Shi, Y.Y. | Deposit date: | 2014-09-19 | Release date: | 2014-12-24 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of the YTH domain of human YTHDF2 in complex with an m(6)A mononucleotide reveals an aromatic cage for m(6)A recognition. Cell Res., 24, 2014
|
|
3WV7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3wv7 by Molmil](/molmil-images/mine/3wv7) | HcgE from Methanothermobacter marburgensis | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Hmd co-occurring protein HcgE | Authors: | Fujishiro, T, Ermler, U, Shima, S. | Deposit date: | 2014-05-16 | Release date: | 2015-04-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Protein-pyridinol thioester precursor for biosynthesis of the organometallic acyl-iron ligand in [Fe]-hydrogenase cofactor Nat Commun, 6, 2015
|
|
3D7R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3d7r by Molmil](/molmil-images/mine/3d7r) | Crystal structure of a putative esterase from Staphylococcus aureus | Descriptor: | BROMIDE ION, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | Authors: | Lam, R, Battaile, K.P, Chan, T, Romanov, V, Lam, K, Soloveychik, M, Wu-Brown, J, Pai, E.F, Chirgadze, N.Y. | Deposit date: | 2008-05-21 | Release date: | 2009-06-09 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Crystal structure of a putative esterase from Staphylococcus aureus To be Published
|
|
3WA2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3wa2 by Molmil](/molmil-images/mine/3wa2) | High resolution crystal structure of copper amine oxidase from arthrobacter globiformis | Descriptor: | 1,2-ETHANEDIOL, COPPER (II) ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Murakawa, T, Hayashi, H, Sunami, T, Kurihara, K, Tamada, T, Kuroki, R, Suzuki, M, Tanizawa, K, Okajima, T. | Deposit date: | 2013-04-22 | Release date: | 2013-09-11 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | High-resolution crystal structure of copper amine oxidase from Arthrobacter globiformis: assignment of bound diatomic molecules as O2 Acta Crystallogr.,Sect.D, 69, 2013
|
|
4R72
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4r72 by Molmil](/molmil-images/mine/4r72) | Structure of the periplasmic binding protein AfuA from Actinobacillus pleuropneumoniae (apo form) | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ABC-type Fe3+ transport system, periplasmic component, ... | Authors: | Sit, B, Calmettes, C, Moraes, T.F. | Deposit date: | 2014-08-26 | Release date: | 2015-08-12 | Last modified: | 2015-09-02 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Active Transport of Phosphorylated Carbohydrates Promotes Intestinal Colonization and Transmission of a Bacterial Pathogen. Plos Pathog., 11, 2015
|
|