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3ZXR
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BU of 3zxr by Molmil
Crystal structure of Mycobacterium Tuberculosis Glutamine Synthetase in complex with tri-substituted imidazole inhibitor (3-(2-tert-butyl- 5-(pyridin-4-yl)-1H-imidazol-4-yl)quinoline) and L-methionine-S- sulfoximine phosphate.
Descriptor: 3-(2-TERT-BUTYL-5-(PYRIDIN-4-YL)-1H-IMIDAZOL-4-YL)QUINOLINE, CHLORIDE ION, GLUTAMINE SYNTHETASE 1, ...
Authors:Nilsson, M.T, Mowbray, S.L.
Deposit date:2011-08-15
Release date:2012-04-04
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Trisubstituted Imidazoles as Mycobacterium Tuberculosis Glutamine Synthetase Inhibitors.
J.Med.Chem., 55, 2012
4LNK
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BU of 4lnk by Molmil
B. subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: structure of GS-glutamate-AMPPCP complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, GLUTAMIC ACID, Glutamine synthetase, ...
Authors:Schumacher, M.A, Chinnam, N, Tonthat, N, Fisher, S, Wray, L.
Deposit date:2013-07-11
Release date:2013-10-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Structures of the Bacillus subtilis Glutamine Synthetase Dodecamer Reveal Large Intersubunit Catalytic Conformational Changes Linked to a Unique Feedback Inhibition Mechanism.
J.Biol.Chem., 288, 2013
4LNF
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BU of 4lnf by Molmil
B. subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: structure of GS-Q
Descriptor: GLUTAMINE, Glutamine synthetase, MAGNESIUM ION, ...
Authors:Schumacher, M.A, Chinnam, N, Tonthat, N, Fisher, S, Wray, L.
Deposit date:2013-07-11
Release date:2013-11-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.949 Å)
Cite:Structures of the Bacillus subtilis Glutamine Synthetase Dodecamer Reveal Large Intersubunit Catalytic Conformational Changes Linked to a Unique Feedback Inhibition Mechanism.
J.Biol.Chem., 288, 2013
4LNN
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BU of 4lnn by Molmil
B. subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: structure of apo form of GS
Descriptor: Glutamine synthetase, MAGNESIUM ION, SULFATE ION
Authors:Schumacher, M.A, Chinnam, N, Tonthat, N, Fisher, S, Wray, L.
Deposit date:2013-07-11
Release date:2013-11-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structures of the Bacillus subtilis Glutamine Synthetase Dodecamer Reveal Large Intersubunit Catalytic Conformational Changes Linked to a Unique Feedback Inhibition Mechanism.
J.Biol.Chem., 288, 2013
4LNI
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BU of 4lni by Molmil
B. subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: structure of the transition state complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Glutamine synthetase, L-METHIONINE-S-SULFOXIMINE PHOSPHATE, ...
Authors:Schumacher, M.A, Chinnam, N, Tonthat, N, Fisher, S, Wray, L.
Deposit date:2013-07-11
Release date:2013-11-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5793 Å)
Cite:Structures of the Bacillus subtilis Glutamine Synthetase Dodecamer Reveal Large Intersubunit Catalytic Conformational Changes Linked to a Unique Feedback Inhibition Mechanism.
J.Biol.Chem., 288, 2013
4LNO
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BU of 4lno by Molmil
B. subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: form two of GS-1
Descriptor: GLUTAMINE, Glutamine synthetase, MAGNESIUM ION
Authors:Schumacher, M.A, Chinnam, N, Tonthat, N, Fisher, S, Wray, L.
Deposit date:2013-07-11
Release date:2013-11-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of the Bacillus subtilis Glutamine Synthetase Dodecamer Reveal Large Intersubunit Catalytic Conformational Changes Linked to a Unique Feedback Inhibition Mechanism.
J.Biol.Chem., 288, 2013
7V4L
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BU of 7v4l by Molmil
Cryo-EM Structure of Camellia sinensis glutamine synthetase CsGSIb inactive Pentamer State III
Descriptor: Glutamine synthetase
Authors:Xu, W, Chen, Y, Xing, Q, Huang, C.
Deposit date:2021-08-13
Release date:2022-05-18
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Assembly status transition offers an avenue for activity modulation of a supramolecular enzyme.
Elife, 10, 2021
7V4J
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Cryo-EM Structure of Camellia sinensis glutamine synthetase CsGSIb inactive Pentamer State I
Descriptor: Glutamine synthetase
Authors:Xu, W, Chen, Y, Xing, Q, Huang, C.
Deposit date:2021-08-13
Release date:2022-05-18
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Assembly status transition offers an avenue for activity modulation of a supramolecular enzyme.
Elife, 10, 2021
7V4I
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BU of 7v4i by Molmil
Cryo-EM Structure of Camellia sinensis glutamine synthetase CsGSIb decamer assembly
Descriptor: Glutamine synthetase
Authors:Xu, W, Chen, Y, Xing, Q, Huang, C.
Deposit date:2021-08-13
Release date:2022-05-18
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Assembly status transition offers an avenue for activity modulation of a supramolecular enzyme.
Elife, 10, 2021
7V4K
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BU of 7v4k by Molmil
Cryo-EM Structure of Camellia sinensis glutamine synthetase CsGSIb inactive Pentamer State II
Descriptor: Glutamine synthetase
Authors:Xu, W, Chen, Y, Xing, Q, Huang, C.
Deposit date:2021-08-13
Release date:2022-05-18
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY
Cite:Assembly status transition offers an avenue for activity modulation of a supramolecular enzyme.
Elife, 10, 2021
8TFK
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BU of 8tfk by Molmil
Cryo-EM structure of the Methanosarcina mazei glutamine synthetase (GS) with Met-Sox-P and ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Glutamine synthetase, L-METHIONINE-S-SULFOXIMINE PHOSPHATE, ...
Authors:Schumacher, M.A.
Deposit date:2023-07-11
Release date:2023-11-15
Last modified:2023-11-29
Method:ELECTRON MICROSCOPY (2.66 Å)
Cite:M. mazei glutamine synthetase and glutamine synthetase-GlnK1 structures reveal enzyme regulation by oligomer modulation.
Nat Commun, 14, 2023
8TFC
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BU of 8tfc by Molmil
Cryo-EM structure of Methanosarcina mazie glutamine synthetase captured as partial oligomer
Descriptor: Glutamine synthetase
Authors:Schumacher, M.A.
Deposit date:2023-07-09
Release date:2023-11-15
Last modified:2023-11-29
Method:ELECTRON MICROSCOPY (6.9 Å)
Cite:M. mazei glutamine synthetase and glutamine synthetase-GlnK1 structures reveal enzyme regulation by oligomer modulation.
Nat Commun, 14, 2023
8TFB
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BU of 8tfb by Molmil
Cryo-EM structure of the Methanosarcina mazei apo glutamin synthetase structure: dodecameric form
Descriptor: Glutamine synthetase, MAGNESIUM ION
Authors:Schumacher, M.A.
Deposit date:2023-07-09
Release date:2023-11-15
Last modified:2023-11-29
Method:ELECTRON MICROSCOPY (2.99 Å)
Cite:M. mazei glutamine synthetase and glutamine synthetase-GlnK1 structures reveal enzyme regulation by oligomer modulation.
Nat Commun, 14, 2023
8TGE
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BU of 8tge by Molmil
Crystal structure of the Methanosarcina mazei glutamine synthetase in complex with GlnK1
Descriptor: Glutamine synthetase, Nitrogen regulatory protein GlnK1
Authors:Schumacher, M.A.
Deposit date:2023-07-12
Release date:2023-11-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:M. mazei glutamine synthetase and glutamine synthetase-GlnK1 structures reveal enzyme regulation by oligomer modulation.
Nat Commun, 14, 2023
8PVG
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BU of 8pvg by Molmil
Structure of E. coli glutamine synthetase determined by cryoEM at 100 keV
Descriptor: Glutamine synthetase
Authors:McMullan, G, Naydenova, K, Mihaylov, D, Peet, M.J, Wilson, H, Yamashita, K, Dickerson, J.L, Chen, S, Cannone, G, Lee, Y, Hutchings, K.A, Gittins, O, Sobhy, M, Wells, T, El-Gomati, M.M, Dalby, J, Meffert, M, Schulze-Briese, C, Henderson, R, Russo, C.J.
Deposit date:2023-07-17
Release date:2023-11-29
Last modified:2023-12-06
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure determination by cryoEM at 100 keV.
Proc.Natl.Acad.Sci.USA, 120, 2023
7W85
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BU of 7w85 by Molmil
Structural of the filamentous Escherichia coli glutamine synthetase
Descriptor: Glutamine synthetase, NICKEL (II) ION
Authors:Huang, P.-C, Chen, S.-K, Wu, K.-P.
Deposit date:2021-12-07
Release date:2022-04-06
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Structural basis for the helical filament formation of Escherichia coli glutamine synthetase.
Protein Sci., 31, 2022
8UFJ
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BU of 8ufj by Molmil
Structure of M. mazei GS(R167L-A168G) apo form
Descriptor: Glutamine synthetase, MAGNESIUM ION
Authors:Schumacher, M.A.
Deposit date:2023-10-04
Release date:2023-11-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:M. mazei glutamine synthetase and glutamine synthetase-GlnK1 structures reveal enzyme regulation by oligomer modulation.
Nat Commun, 14, 2023
7CPR
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BU of 7cpr by Molmil
glutamine synthetase from Drosophila
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Glutamine synthetase 2 cytoplasmic
Authors:Yin, H.S, Chen, W.T.
Deposit date:2020-08-07
Release date:2021-08-11
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Structural Insight into the Contributions of the N-Terminus and Key Active-Site Residues to the Catalytic Efficiency of Glutamine Synthetase 2.
Biomolecules, 10, 2020
7TFB
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BU of 7tfb by Molmil
P. polymyxa GS(14)-Q-GlnR peptide
Descriptor: GLUTAMINE, GlnR C-tail peptide, Glutamine synthetase, ...
Authors:Travis, B.A, Peck, J, Schumacher, M.A.
Deposit date:2022-01-06
Release date:2022-06-29
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (2.28 Å)
Cite:Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
7TDP
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BU of 7tdp by Molmil
Structure of Paenibacillus polymyxa GS bound to Met-Sox-P-ADP (Transition state complex) to 1.98 Angstom
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Glutamine synthetase, L-METHIONINE-S-SULFOXIMINE PHOSPHATE, ...
Authors:Schumacher, M.A.
Deposit date:2022-01-02
Release date:2022-06-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
7TF9
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BU of 7tf9 by Molmil
L. monocytogenes GS(14)-Q-GlnR peptide
Descriptor: C-tail peptide of Glutamine synthetase repressor, GLUTAMINE, Glutamine synthetase, ...
Authors:Travis, B.A, Peck, J, Schumacher, M.A.
Deposit date:2022-01-06
Release date:2022-06-29
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
7TFA
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BU of 7tfa by Molmil
P. polymyxa GS(12)-Q-GlnR peptide
Descriptor: GLUTAMINE, GlnR C-tail peptide, Glutamine synthetase, ...
Authors:Travis, B.A, Peck, J, Schumacher, M.A.
Deposit date:2022-01-06
Release date:2022-06-29
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (2.07 Å)
Cite:Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
7TF6
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BU of 7tf6 by Molmil
S. aureus GS(12)-Q-GlnR peptide
Descriptor: GLUTAMINE, Glutamine synthetase, MAGNESIUM ION, ...
Authors:Travis, B.A, Peck, J, Schumacher, M.A.
Deposit date:2022-01-06
Release date:2022-06-29
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (2.15 Å)
Cite:Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
7TF7
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BU of 7tf7 by Molmil
S. aureus GS(12) - apo
Descriptor: Glutamine synthetase
Authors:Travis, B.A, Peck, J, Schumacher, M.A.
Deposit date:2022-01-06
Release date:2022-06-29
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (2.13 Å)
Cite:Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022
7TFE
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BU of 7tfe by Molmil
L. monocytogenes GS(12) - apo
Descriptor: Glutamine synthetase, MAGNESIUM ION
Authors:Travis, B.A, Peck, J, Schumacher, M.A.
Deposit date:2022-01-06
Release date:2022-06-29
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Molecular dissection of the glutamine synthetase-GlnR nitrogen regulatory circuitry in Gram-positive bacteria.
Nat Commun, 13, 2022

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