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2PFF	Structural Insights of Yeast Fatty Acid Synthase Descriptor: Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, Tail protein Authors: Xiong, Y, Lomakin, I.B, Steitz, T.A. Deposit date: 2007-04-04 Release date: 2007-07-10 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (4 Å) Cite: Structural Insights of Yeast Fatty Acid Synthase Cell(Cambridge,Mass.), 129, 2007
2QO3	Crystal Structure of [KS3][AT3] didomain from module 3 of 6-deoxyerthronolide B synthase Descriptor: (2S, 3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE, ACETATE ION, ... Authors: Khosla, C, Cane, E.D, Tang, Y, Chen, Y.A, Kim, C.Y. Deposit date: 2007-07-19 Release date: 2007-09-04 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2.59 Å) Cite: Structural and mechanistic analysis of protein interactions in module 3 of the 6-deoxyerythronolide B synthase Chem.Biol., 14, 2007
2RJT	Crystal Structure Analysis of a Surface Entropy Reduction Mutant of S. pneumoniae FabF Descriptor: Beta-ketoacyl-ACP synthase II Authors: Soisson, S.M, Parthasarathy, G, Becker, J. Deposit date: 2007-10-15 Release date: 2008-01-22 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Surface-entropy reduction approaches to manipulate crystal forms of beta-ketoacyl acyl carrier protein synthase II from Streptococcus pneumoniae. Acta Crystallogr.,Sect.D, 64, 2008
5ELP	Ketosynthase from module 1 of the bacillaene synthase from Bacillus amyloliquefaciens FZB42 Descriptor: NRPS/PKS protein Authors: Wagner, D.T, Gay, D.C, Keatinge-Clay, A.T, Zogzas, C.E. Deposit date: 2015-11-04 Release date: 2016-01-13 Last modified: 2016-11-02 Method: X-RAY DIFFRACTION (2.93 Å) Cite: The LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex. J.Struct.Biol., 193, 2016
5ERF	Ketosynthase from module 6 of the bacillaene synthase from Bacillus subtilis 168 Descriptor: Polyketide synthase PksL Authors: Wagner, D.T, Gay, D.C, Keatinge-Clay, A.T. Deposit date: 2015-11-14 Release date: 2015-12-23 Last modified: 2019-12-25 Method: X-RAY DIFFRACTION (3.1 Å) Cite: The LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex. J.Struct.Biol., 193, 2016
7ZM9	Ketosynthase domain 3 of Brevibacillus Brevis orphan BGC11 Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, Putative polyketide synthase Authors: Tittes, Y.U, Herbst, D.A, Jakob, R.P, Maier, T. Deposit date: 2022-04-19 Release date: 2022-09-21 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.62 Å) Cite: The structure of a polyketide synthase bimodule core. Sci Adv, 8, 2022
7ZMD	Ketosynthase domain of module 3 from Brevibacillus Brevis orphan BGC11 Descriptor: Putative polyketide synthase Authors: Tittes, Y.U, Herbst, D.A, Jakob, R.P, Maier, T. Deposit date: 2022-04-19 Release date: 2022-09-21 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (2.93 Å) Cite: The structure of a polyketide synthase bimodule core. Sci Adv, 8, 2022
7ZMC	Ketosynthase domain of module 4 from Brevibacillus Brevis orphan BGC11 Descriptor: Putative polyketide synthase Authors: Tittes, Y.U, Herbst, D.A, Jakob, R.P, Maier, T. Deposit date: 2022-04-19 Release date: 2022-09-21 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (3.1 Å) Cite: The structure of a polyketide synthase bimodule core. Sci Adv, 8, 2022
7ZMA	Ketosynthase domain of module 4 from Brevibacillus Brevis orphan BGC11 Descriptor: Putative polyketide synthase Authors: Tittes, Y.U, Herbst, D.A, Jakob, R.P, Maier, T. Deposit date: 2022-04-19 Release date: 2022-09-21 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (2.9 Å) Cite: The structure of a polyketide synthase bimodule core. Sci Adv, 8, 2022
7ZSK	K3DAK4 bimodule core of BGC11 from Brevibacillus brevis. Descriptor: Putative polyketide synthase Authors: Tittes, Y.U, Herbst, D.A, Jakob, R.P, Maier, T. Deposit date: 2022-05-07 Release date: 2022-09-21 Last modified: 2024-07-24 Method: ELECTRON MICROSCOPY (6.8 Å) Cite: The structure of a polyketide synthase bimodule core. Sci Adv, 8, 2022
7CPY	Lovastatin nonaketide synthase with LovC Descriptor: Lovastatin nonaketide synthase, enoyl reductase component lovC, polyketide synthase component, ... Authors: Wang, J, Wang, Z. Deposit date: 2020-08-08 Release date: 2021-01-13 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structural basis for the biosynthesis of lovastatin. Nat Commun, 12, 2021
7CPX	Lovastatin nonaketide synthase Descriptor: Lovastatin nonaketide synthase, polyketide synthase component, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Wang, J, Wang, Z. Deposit date: 2020-08-08 Release date: 2021-01-13 Last modified: 2024-05-29 Method: ELECTRON MICROSCOPY (2.91 Å) Cite: Structural basis for the biosynthesis of lovastatin. Nat Commun, 12, 2021
4CW4	Crystal structure of the noncanonical ketosynthase FabY from P. aeruginosa Descriptor: BETA-KETOACYL SYNTHASE, CHLORIDE ION, SULFATE ION Authors: Bukhari, H.S.T, Jakob, R.P, Maier, T. Deposit date: 2014-04-01 Release date: 2014-12-17 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.349 Å) Cite: Evolutionary Origins of the Multienzyme Architecture of Giant Fungal Fatty Acid Synthase. Structure, 22, 2014
4DDO	Crystal structure of 3-oxoacyl-[acyl-carrier-protein] synthase ii from burkholderia vietnamiensis Descriptor: 3-oxoacyl-[acyl-carrier-protein] synthase 2, SODIUM ION Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2012-01-19 Release date: 2012-05-23 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013
5ENY	Ketosynthase from module 6 connected to acyl carrier protein from module 5 (unobservable) of the bacillaene synthase from Bacillus subtilis 168 Descriptor: Polyketide synthase PksL Authors: Wagner, D.T, Gay, D.C, Keatinge-Clay, A.T. Deposit date: 2015-11-09 Release date: 2015-12-23 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (4 Å) Cite: The LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex. J.Struct.Biol., 193, 2016
5ERB	Ketosynthase from module 5 of the bacillaene synthase from Bacillus amyloliquefaciens FZB42 Descriptor: Polyketide synthase Authors: Wagner, D.T, Gay, D.C, Keatinge-Clay, A.T, Meinke, J. Deposit date: 2015-11-13 Release date: 2015-12-23 Last modified: 2017-09-27 Method: X-RAY DIFFRACTION (4.2 Å) Cite: The LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex. J.Struct.Biol., 193, 2016
7BC4	Cryo-EM structure of fatty acid synthase (FAS) from Pichia pastoris Descriptor: FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta Authors: Snowden, J.S, Alzahrani, J, Sherry, L, Stacey, M, Rowlands, D.J, Ranson, N.A, Stonehouse, N.J. Deposit date: 2020-12-18 Release date: 2021-05-19 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural insight into Pichia pastoris fatty acid synthase. Sci Rep, 11, 2021
8CG5	The ACP crosslinked to the KS of the cercosporin fungal non-reducing polyketide synthase (NR-PKS) CTB1 (SAT-KS:ACP-MAT) Descriptor: Acyl carrier protein (ACP) of Non-reducing polyketide synthase CTB1, Non-reducing polyketide synthase CTB1, N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-N-[2-(propanoylamino)ethyl]-beta-alaninamide Authors: Munoz-Hernandez, H, Tittes, Y.U, Maier, T. Deposit date: 2023-02-03 Release date: 2024-02-21 Method: ELECTRON MICROSCOPY (2.7 Å) Cite: CryoEM structure of ACP crosslinked to KS of the cercosporin fungal non-reducing polyketide synthase (NR-PKS) CTB1 (SAT-KS:ACP-MAT) at 2.7 Angstroms resolution To Be Published
8CG4	The organise full-length structure of the fungal non-reducing polyketide synthase (NR-PKS) PksA Descriptor: Norsolorinic acid synthase Authors: Munoz-Hernandez, H, Maier, T. Deposit date: 2023-02-03 Release date: 2024-02-21 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: CryoEM structure of the Aspergilus sp. fungal non-reducing polyketide synthase (NR-PKS) PksA at 2.6 Angstroms resolution To Be Published
7BC5	Cryo-EM structure of ACP domain from Pichia pastoris fatty acid synthase (FAS) Descriptor: Fatty acid synthase subunit alpha Authors: Snowden, J.S, Alzahrani, J, Sherry, L, Stacey, M, Rowlands, D.J, Ranson, N.A, Stonehouse, N.J. Deposit date: 2020-12-18 Release date: 2021-05-19 Last modified: 2024-05-01 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural insight into Pichia pastoris fatty acid synthase. Sci Rep, 11, 2021
8CJH	Architecture of a PKS-NRPS hybrid megaenzyme involved in the biosynthesis of the genotoxin colibactin Descriptor: Colibactin hybrid non-ribosomal peptide synthetase/type I polyketide synthase ClbK Authors: Bonhomme, S, Dessen, A, Macheboeuf, P. Deposit date: 2023-02-13 Release date: 2023-04-26 Last modified: 2024-06-19 Method: X-RAY DIFFRACTION (2.982 Å) Cite: Architecture of a PKS-NRPS hybrid megaenzyme involved in the biosynthesis of the genotoxin colibactin. Structure, 31, 2023
4EWG	Crystal structure of a Beta-ketoacyl synthase from Burkholderia phymatum STM815 Descriptor: 1,2-ETHANEDIOL, Beta-ketoacyl synthase, CALCIUM ION, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2012-04-26 Release date: 2012-05-16 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013
4F32	Crystal structure of 3-oxoacyl-[acyl-carrier-protein] synthase II from Burkholderia vietnamiensis in complex with platencin Descriptor: 1,2-ETHANEDIOL, 2,4-dihydroxy-3-({3-[(2S,4aS,8S,8aR)-8-methyl-3-methylidene-7-oxo-1,3,4,7,8,8a-hexahydro-2H-2,4a-ethanonaphthalen-8-yl]propanoyl}amino)benzoic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 2, ... Authors: Seattle Structural Genomics Center for Infectious Disease (SSGCID) Deposit date: 2012-05-08 Release date: 2012-05-23 Last modified: 2014-02-12 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Combining functional and structural genomics to sample the essential Burkholderia structome. Plos One, 8, 2013
2IWY	Human mitochondrial beta-ketoacyl ACP synthase Descriptor: 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, AMMONIUM ION Authors: Christensen, C.E, Kragelund, B.B, von Wettstein-Knowles, P, Henriksen, A. Deposit date: 2006-07-05 Release date: 2007-02-06 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.06 Å) Cite: Structure of the Human Beta-Ketoacyl [Acp] Synthase from the Mitochondrial Type II Fatty Acid Synthase. Protein Sci., 16, 2007
6TA1	Fatty acid synthase of S. cerevisiae Descriptor: FLAVIN MONONUCLEOTIDE, Fatty acid synthase subunit alpha, Fatty acid synthase subunit beta, ... Authors: Vonck, J, D'Imprima, E, Joppe, M, Grininger, M. Deposit date: 2019-10-29 Release date: 2019-11-06 Last modified: 2020-05-20 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: The resolution revolution in cryoEM requires high-quality sample preparation: a rapid pipeline to a high-resolution map of yeast fatty acid synthase. Iucrj, 7, 2020

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