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8QX8
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BU of 8qx8 by Molmil
Endosomal membrane tethering complex CORVET
Descriptor: E3 ubiquitin-protein ligase PEP5, Vacuolar membrane protein PEP3, Vacuolar protein sorting-associated protein 16, ...
Authors:Shvarev, D, Ungermann, C, Moeller, A.
Deposit date:2023-10-23
Release date:2024-07-03
Last modified:2024-07-24
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structure of the endosomal CORVET tethering complex.
Nat Commun, 15, 2024
8JN8
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BU of 8jn8 by Molmil
Crystal structure of c-Src in complex with covalent inhibitor DC-Srci-6668
Descriptor: (2R)-N-cyclopentyl-2-[cyclopropyl(ethanoyl)amino]-2-(4-fluorophenyl)ethanamide, Proto-oncogene tyrosine-protein kinase Src
Authors:Zhang, H.M, Luo, C.
Deposit date:2023-06-06
Release date:2024-06-12
Method:X-RAY DIFFRACTION (1.902 Å)
Cite:The crystal structure of c-Src in complex with covalent inhibitor DC-Srci-6668
To Be Published
8JN9
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BU of 8jn9 by Molmil
Crystal structure of c-Src in complex with covalent inhibitor LW-Srci-8
Descriptor: N-[(1R)-1-[3,5-bis(fluoranyl)phenyl]-2-(cyclopentylamino)-2-oxidanylidene-ethyl]-N-cyclopropyl-prop-2-enamide, Proto-oncogene tyrosine-protein kinase Src
Authors:Zhang, H.M, Luo, C.
Deposit date:2023-06-06
Release date:2024-06-12
Method:X-RAY DIFFRACTION (2.724 Å)
Cite:The crystal structure of c-Src in complex with covalent inhibitor LW-Srci-8
To Be Published
7UZS
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BU of 7uzs by Molmil
Protein 4.2 (local refinement from consensus reconstruction of ankyrin complex classes)
Descriptor: Protein 4.2
Authors:Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
Deposit date:2022-05-09
Release date:2022-07-20
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.2 Å)
Cite:Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
7V19
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BU of 7v19 by Molmil
Local refinement of Band 3-II transmembrane domains, class 1 of erythrocyte ankyrin-1 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Band 3 anion transport protein, CHOLESTEROL, ...
Authors:Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
Deposit date:2022-05-11
Release date:2022-07-20
Last modified:2022-07-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
7V0Q
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BU of 7v0q by Molmil
Local refinement of protein 4.2, class 1 of erythrocyte ankyrin-1 complex
Descriptor: Protein 4.2
Authors:Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
Deposit date:2022-05-10
Release date:2022-07-20
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
7UZV
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BU of 7uzv by Molmil
Cytoplasmic domains of Band 3-I (local refinement from consensus reconstruction of ankyrin complexes)
Descriptor: Band 3 anion transport protein
Authors:Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
Deposit date:2022-05-09
Release date:2022-07-20
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
7V07
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BU of 7v07 by Molmil
Band 3-I-TM local refinement from erythrocyte ankyrin-1 complex consensus reconstruction
Descriptor: Band 3 anion transport protein, CHOLESTEROL, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
Deposit date:2022-05-10
Release date:2022-07-20
Last modified:2022-07-27
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
7UZ3
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BU of 7uz3 by Molmil
Band 3-Glycophorin A complex, outward facing
Descriptor: Band 3 anion transport protein, CHOLESTEROL, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
Deposit date:2022-05-08
Release date:2022-07-20
Last modified:2022-07-27
Method:ELECTRON MICROSCOPY (2.35 Å)
Cite:Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
7V0U
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BU of 7v0u by Molmil
Local refinement of Band 3-II cytoplasmic domains, class 1 of erythrocyte ankyrin-1 complex
Descriptor: Band 3 anion transport protein
Authors:Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
Deposit date:2022-05-11
Release date:2022-07-20
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
7UZU
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BU of 7uzu by Molmil
Ankyrin-1 (N-terminal region of membrane binding domain, local refinement from consensus reconstruction; bound to N-terminal peptide from band 3)
Descriptor: Ankyrin-1, Band 3 anion transport protein
Authors:Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
Deposit date:2022-05-09
Release date:2022-07-20
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
7UZQ
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BU of 7uzq by Molmil
Local refinement of RhAG-RhCE-ANK1(AR1-5), from consensus refinement of all classes
Descriptor: Ammonium transporter Rh type A, Ankyrin-1, Blood group Rh(CE) polypeptide, ...
Authors:Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
Deposit date:2022-05-09
Release date:2022-07-20
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.17 Å)
Cite:Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
7V0T
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BU of 7v0t by Molmil
Local refinement of Band 3-I cytoplasmic domains, class 1 of erythrocyte ankyrin-1 complex
Descriptor: Band 3 anion transport protein
Authors:Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
Deposit date:2022-05-11
Release date:2022-07-20
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
7V0Y
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BU of 7v0y by Molmil
Local refinement of Band 3-III cytoplasmic domains, class 1 of erythrocyte ankyrin-1 complex
Descriptor: Band 3 anion transport protein
Authors:Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
Deposit date:2022-05-11
Release date:2022-07-20
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
7V0S
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BU of 7v0s by Molmil
Local refinement of RhAG/CE trimer, class 1 of erythrocyte ankyrin-1 complex
Descriptor: Ammonium transporter Rh type A, Ankyrin-1, Blood group Rh(CE) polypeptide, ...
Authors:Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
Deposit date:2022-05-10
Release date:2022-07-20
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
7V0X
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BU of 7v0x by Molmil
Local refinement of ankyrin-1 (C-terminal half), class 1 of erythrocyte ankyrin-1 complex
Descriptor: Ankyrin-1
Authors:Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
Deposit date:2022-05-11
Release date:2022-07-20
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
7V0M
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BU of 7v0m by Molmil
Local refinement of ankyrin-1 (N-terminal half), class 1 of erythrocyte ankyrin-1 complex
Descriptor: Ankyrin-1, Band 3 anion transport protein
Authors:Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
Deposit date:2022-05-10
Release date:2022-07-20
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
7V0K
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BU of 7v0k by Molmil
Consensus refinement of human erythrocyte ankyrin-1 complex (Composite map)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Ammonium transporter Rh type A, Ankyrin-1, ...
Authors:Vallese, F, Kim, K, Yen, L.Y, Johnston, J.D, Noble, A.J, Cali, T, Clarke, O.B.
Deposit date:2022-05-10
Release date:2022-07-20
Last modified:2022-07-27
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Architecture of the human erythrocyte ankyrin-1 complex.
Nat.Struct.Mol.Biol., 29, 2022
6QI8
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BU of 6qi8 by Molmil
Truncated human R2TP complex, structure 3 (ADP-filled)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2
Authors:Munoz-Hernandez, H, Rodriguez, C.F, Llorca, O.
Deposit date:2019-01-18
Release date:2019-04-10
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM.
Sci Adv, 5, 2019
7UX9
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BU of 7ux9 by Molmil
Arabidopsis DDM1 bound to nucleosome (H2A.W, H2B, H3.3, H4, with 147 bp DNA)
Descriptor: ATP-dependent DNA helicase DDM1, DNA (antisense strand), DNA (sense strand), ...
Authors:Ipsaro, J.J, Adams, D.W, Joshua-Tor, L.
Deposit date:2022-05-05
Release date:2023-08-09
Last modified:2023-09-27
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Chromatin remodeling of histone H3 variants by DDM1 underlies epigenetic inheritance of DNA methylation.
Cell, 186, 2023
5ND0
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BU of 5nd0 by Molmil
ENAH EVH1 in complex with Ac-[2-Cl-F]-PP-[ProM-1]-TEDEL-NH2
Descriptor: 5,6-DIHYDRO-BENZO[H]CINNOLIN-3-YLAMINE, NITRATE ION, Protein enabled homolog, ...
Authors:Barone, M, Roske, Y.
Deposit date:2017-03-07
Release date:2018-03-21
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Proc.Natl.Acad.Sci.USA, 117, 2020
8KCB
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BU of 8kcb by Molmil
Complex of DDM1-nucleosome(H2A) complex with DDM1 bound to SHL2
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase DDM1, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Zhang, H, Zhang, Y.
Deposit date:2023-08-07
Release date:2024-06-26
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (3.17 Å)
Cite:Mechanism of heterochromatin remodeling revealed by the DDM1 bound nucleosome structures.
Structure, 32, 2024
8KCC
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BU of 8kcc by Molmil
Complex of DDM1-nucleosome(H2A.W) complex with DDM1 bound to SHL2
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase DDM1, BERYLLIUM TRIFLUORIDE ION, ...
Authors:Zhang, H, Zhang, Y.
Deposit date:2023-08-07
Release date:2024-06-26
Last modified:2024-08-21
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Mechanism of heterochromatin remodeling revealed by the DDM1 bound nucleosome structures.
Structure, 32, 2024
5NC2
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BU of 5nc2 by Molmil
ENAH EVH1 in complex with Ac-[2-Cl-F]-PPPPTEDEL-NH2
Descriptor: Ac-[2-Cl-F]PPPPTEDEL-NH2, NITRATE ION, Protein enabled homolog, ...
Authors:Barone, M, Roske, Y.
Deposit date:2017-03-03
Release date:2018-03-21
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Proc.Natl.Acad.Sci.USA, 117, 2020
8SCZ
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BU of 8scz by Molmil
Cryo-EM structure of 14aa-GS RIG-I in complex with p3SLR30
Descriptor: Antiviral innate immune response receptor RIG-I, ZINC ION, p3SLR30
Authors:Wang, W, Pyle, A.M.
Deposit date:2023-04-06
Release date:2024-03-13
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structure of 14aa-GS RIG-I in complex with p3SLR30
To Be Published

224931

건을2024-09-11부터공개중

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