PDB: 66724 resultsInfo pagesStatus searchChemie searchBIRD

---

4U6W	HsMetAP (F220M) in complex with 1-amino-2-propylpentyl]phosphonic acid Descriptor: COBALT (II) ION, GLYCEROL, Methionine aminopeptidase 1, ... Authors: Arya, T, Addlagatta, A. Deposit date: 2014-07-30 Release date: 2015-03-25 Last modified: 2019-11-20 Method: X-RAY DIFFRACTION (1.83 Å) Cite: Identification of the Molecular Basis of Inhibitor Selectivity between the Human and Streptococcal Type I Methionine Aminopeptidases J.Med.Chem., 58, 2015
4U71	HsMetAP(F309M) IN COMPLEX WITH 1- amino(cyclohexyl)methy)phosphonic acid Descriptor: COBALT (II) ION, GLYCEROL, Methionine aminopeptidase 1, ... Authors: Arya, T, Addlagatta, A. Deposit date: 2014-07-30 Release date: 2015-03-25 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Identification of the Molecular Basis of Inhibitor Selectivity between the Human and Streptococcal Type I Methionine Aminopeptidases J.Med.Chem., 58, 2015
3GJP	Crystal structure of mutant coiled coil GCN4 leucine zipper Descriptor: General control protein GCN4 Authors: Honnappa, S, Steinmetz, M.O. Deposit date: 2009-03-09 Release date: 2010-03-09 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2 Å) Cite: Molecular basis of coiled-coil oligomerization-state specificity Proc.Natl.Acad.Sci.USA, 107, 2010
4TY9	An Ligand-observed Mass Spectrometry-based Approach Integrated into the Fragment Based Lead Discovery Pipeline Descriptor: 5-(trifluoromethyl)pyridin-2-amine, Polyprotein Authors: Shui, W, Yang, C, Lin, J, Chen, X, Qin, S, Chen, S. Deposit date: 2014-07-08 Release date: 2015-05-06 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.78 Å) Cite: A ligand-observed mass spectrometry approach integrated into the fragment based lead discovery pipeline Sci Rep, 5, 2015
3GNU	Toxin fold as basis for microbial attack and plant defense Descriptor: 25 kDa protein elicitor, CHLORIDE ION, GUANIDINE Authors: Ottmann, C, Luberacki, B, Kuefner, I, Koch, W, Brunner, F, Weyand, M, Mattinen, L, Pirhonen, M, Anderluh, G, Seitz, H.U, Nuernberger, T, Oecking, C. Deposit date: 2009-03-18 Release date: 2009-06-09 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: A common toxin fold mediates microbial attack and plant defense Proc.Natl.Acad.Sci.USA, 106, 2009
4TYB	An Ligand-observed Mass Spectrometry-based Approach Integrated into the Fragment Based Lead Discovery Pipeline Descriptor: (2R)-morpholin-4-yl(phenyl)ethanenitrile, Polyprotein Authors: Shui, W, Yang, C, Lin, J, Chen, X, Qin, S, Chen, S. Deposit date: 2014-07-08 Release date: 2015-05-20 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.93 Å) Cite: A ligand-observed mass spectrometry approach integrated into the fragment based lead discovery pipeline Sci Rep, 5, 2015
3GRR	Crystal Structure of the complex between S-Adenosyl Homocysteine and Methanocaldococcus jannaschi Dim1. Descriptor: Dimethyladenosine transferase, S-ADENOSYL-L-HOMOCYSTEINE Authors: Scarsdale, J.N, Musayev, F.N, Rife, J.P. Deposit date: 2009-03-26 Release date: 2010-03-31 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Binding of adenosine-based ligands to the MjDim1 rRNA methyltransferase: implications for reaction mechanism and drug design. Biochemistry, 49, 2010
3GRV	Crystal Structure of the Complex between Adenosine and Methanocaldococcus jannaschi Dim1 Descriptor: ADENOSINE, Dimethyladenosine transferase, SULFATE ION Authors: Scarsdale, J.N, Musayev, F.N, Rife, J.P. Deposit date: 2009-03-26 Release date: 2010-03-31 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Binding of adenosine-based ligands to the MjDim1 rRNA methyltransferase: implications for reaction mechanism and drug design. Biochemistry, 49, 2010
7WA8	Strigolactone receptors in Striga ShHTL7 Descriptor: Hyposensitive to light 7 Authors: Wang, Y, Yao, R. Deposit date: 2021-12-12 Release date: 2022-01-05 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.33 Å) Cite: Molecular basis for high ligand sensitivity and selectivity of strigolactone receptors in Striga. Plant Physiology, Volume 185, 2021
3H1G	Crystal structure of Chey mutant T84A of helicobacter pylori Descriptor: Chemotaxis protein cheY homolog, MAGNESIUM ION, SULFATE ION Authors: Lam, K.H, Ling, T.K, Au, S.W. Deposit date: 2009-04-12 Release date: 2010-03-09 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal structure of activated CheY1 from Helicobacter pylori. J.Bacteriol., 192, 2010
4XN2	Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-Leucine Descriptor: Aminopeptidase N, GLYCEROL, LEUCINE, ... Authors: Addlagatta, A, Gumpena, R. Deposit date: 2015-01-15 Release date: 2016-03-02 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.11 Å) Cite: Crystal Structure of Met260Ala mutant of E. coli Aminopeptidase N in complex with L-Leucine To Be Published
4TYA	An Ligand-observed Mass Spectrometry-based Approach Integrated into the Fragment Based Lead Discovery Pipeline Descriptor: 4-(trifluoromethyl)benzoic acid, Polyprotein Authors: Shui, W, Yang, C, Lin, J, Chen, X, Qin, S, Chen, S. Deposit date: 2014-07-08 Release date: 2015-05-06 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (2.94 Å) Cite: A ligand-observed mass spectrometry approach integrated into the fragment based lead discovery pipeline Sci Rep, 5, 2015
6G5U	Crystal structure of human carbonic anhydrase isozyme XIII with N-butyl-2,4-dichloro-5-sulfamoyl-benzamide Descriptor: 1,2-ETHANEDIOL, CITRIC ACID, Carbonic anhydrase 13, ... Authors: Smirnov, A, Manakova, E, Grazulis, S. Deposit date: 2018-03-30 Release date: 2019-03-13 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Design of two-tail compounds with rotationally fixed benzenesulfonamide ring as inhibitors of carbonic anhydrases. Eur J Med Chem, 156, 2018
4ZAU	AZD9291 complex with wild type EGFR Descriptor: Epidermal growth factor receptor, N-(2-{[2-(dimethylamino)ethyl](methyl)amino}-4-methoxy-5-{[4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl]amino}phenyl)prop-2-enamide Authors: Squire, C.J, Yosaatmadja, Y, Flanagan, J.U, McKeage, M. Deposit date: 2015-04-14 Release date: 2015-11-11 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Binding mode of the breakthrough inhibitor AZD9291 to epidermal growth factor receptor revealed. J.Struct.Biol., 192, 2015
4R56	Crystal structure of Sulfolobus Cren7-dsDNA(GTGATCAC) complex Descriptor: Chromatin protein Cren7, DNA (5'-D(*GP*TP*GP*AP*TP*CP*AP*C)-3') Authors: Zhang, Z.F, Gong, Y, Chen, Y.Y, Li, H.B, Huang, L. Deposit date: 2014-08-20 Release date: 2015-08-05 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Insights into the interaction between Cren7 and DNA: the role of loop beta 3-beta 4 Extremophiles, 19, 2015
4QQ8	Crystal structure of the formolase FLS in space group P 43 21 2 Descriptor: 1,2-ETHANEDIOL, Formolase, MAGNESIUM ION, ... Authors: Shen, B.W, Siegel, J.B, Stoddard, B.L. Deposit date: 2014-06-26 Release date: 2015-03-11 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.88 Å) Cite: Computational protein design enables a novel one-carbon assimilation pathway. Proc.Natl.Acad.Sci.USA, 112, 2015
4ZFP	A new crystal structure for the adduct formed in the reaction between AuSac2, a cytotoxic homoleptic gold(I) compound with the saccharinate ligand, and the model protein hen egg white lysozyme Descriptor: 1,2-ETHANEDIOL, GOLD ION, Lysozyme C, ... Authors: Merlino, A. Deposit date: 2015-04-21 Release date: 2015-06-24 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Structural evidences for a secondary gold binding site in the hydrophobic box of lysozyme. Biometals, 28, 2015
2F35	Crystal Structure of the GluR5 Ligand Binding Core with UBP302 At 1.87 Angstroms Resolution Descriptor: (S)-1-(2-AMINO-2-CARBOXYETHYL)-3-(2-CARBOXYBENZYL)PYRIMIDINE-2,4-DIONE, CHLORIDE ION, GLUTAMATE RECEPTOR, ... Authors: Mayer, M.L. Deposit date: 2005-11-18 Release date: 2006-04-04 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.87 Å) Cite: Crystal structures of the kainate receptor GluR5 ligand binding core dimer with novel GluR5-selective antagonists. J.Neurosci., 26, 2006
3H1F	Crystal structure of CheY mutant D53A of Helicobacter pylori Descriptor: Chemotaxis protein cheY homolog, MAGNESIUM ION, SULFATE ION Authors: Lam, K.H, Ling, T.K, Au, S.W. Deposit date: 2009-04-12 Release date: 2010-03-09 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure of activated CheY1 from Helicobacter pylori. J.Bacteriol., 192, 2010
4U75	HsMetAP (F309M) in complex with Methionine Descriptor: COBALT (II) ION, GLYCEROL, METHIONINE, ... Authors: Arya, T, Addlagatta, A. Deposit date: 2014-07-30 Release date: 2015-03-25 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.94 Å) Cite: Identification of the Molecular Basis of Inhibitor Selectivity between the Human and Streptococcal Type I Methionine Aminopeptidases J.Med.Chem., 58, 2015
2FU0	Plasmodium falciparum cyclophilin PFE0505w putative cyclosporin-binding domain Descriptor: cyclophilin, putative Authors: Dong, A, Lew, J, Sundararajan, E, Zhao, Y, Wasney, G, Vedadi, M, Koeieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Hills, T, Structural Genomics Consortium (SGC) Deposit date: 2006-01-25 Release date: 2006-02-07 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms. Mol.Biochem.Parasitol., 151, 2007
3H3P	Crystal structure of HIV epitope-scaffold 4E10 Fv complex Descriptor: 4E10_S0_1TJLC_004_N, CALCIUM ION, Fv 4E10 heavy chain, ... Authors: Holmes, M.A. Deposit date: 2009-04-16 Release date: 2010-01-19 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Interactions between lipids and human anti-HIV antibody 4E10 can be reduced without ablating neutralizing activity J.Virol., 84, 2010
4UCF	Crystal structure of Bifidobacterium bifidum beta-galactosidase in complex with alpha-galactose Descriptor: BETA-GALACTOSIDASE, DI(HYDROXYETHYL)ETHER, N-PROPANOL, ... Authors: Godoy, A.S, Murakami, M.T, Camilo, C.M, Bernardes, A, Polikarpov, I. Deposit date: 2014-12-03 Release date: 2016-01-20 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (1.94 Å) Cite: Crystal Structure of Beta1-6-Galactosidase from Bifidobacterium Bifidum S17: Trimeric Architecture, Molecular Determinants of the Enzymatic Activity and its Inhibition by Alpha-Galactose. FEBS J., 283, 2016
3GLZ	Human Transthyretin (TTR) complexed with(E)-3-(2-(trifluoromethyl)benzylideneaminooxy)propanoic acid (inhibitor 11) Descriptor: 3-[({(1E)-[2-(trifluoromethyl)phenyl]methylidene}amino)oxy]propanoic acid, Transthyretin Authors: Mohamedmohaideen, N.N, Palaninathan, S.K, Orlandini, E, Sacchettini, J.C. Deposit date: 2009-03-12 Release date: 2009-07-28 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.78 Å) Cite: Novel transthyretin amyloid fibril formation inhibitors: synthesis, biological evaluation, and X-ray structural analysis Plos One, 4, 2009
4U6Z	HsMetAP(F309M) in complex with 1-amino-2-propylpentyl)phosphonic acid Descriptor: COBALT (II) ION, GLYCEROL, Methionine aminopeptidase 1, ... Authors: Arya, T, Addlagatta, A. Deposit date: 2014-07-30 Release date: 2015-04-15 Last modified: 2024-03-20 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Identification of the Molecular Basis of Inhibitor Selectivity between the Human and Streptococcal Type I Methionine Aminopeptidases J.Med.Chem., 58, 2015

<278279280281282283284285286287288289290291292293>