PDB: 72308 resultsInfo pagesStatus searchChemie searchBIRD

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6NFW	Potyvirus viral protein genome linked (VPg) emulates the m7G cap to recruit the eukaryotic translation initiation factor eIF4E Descriptor: VPg Authors: Borden, K, Volpon, L, Osborne, M. Deposit date: 2018-12-21 Release date: 2019-11-06 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Structural studies of the eIF4E-VPg complex reveal a direct competition for capped RNA: Implications for translation. Proc.Natl.Acad.Sci.USA, 116, 2019
7BOG	Bacterial 30S ribosomal subunit assembly complex state E (body domain) Descriptor: 16S rRNA, 30S ribosomal protein S11, 30S ribosomal protein S12, ... Authors: Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Lopez-Alonso, J, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S. Deposit date: 2021-01-25 Release date: 2021-07-07 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (2.75 Å) Cite: A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit. Sci Adv, 7, 2021
4YFX	Escherichia coli RNA polymerase in complex with Myxopyronin B Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Molodtsov, V, Fleming, P.R, Eyermann, C.J, Ferguson, A.D, Foulk, M.A, McKinney, D.C, Masse, C.E, Buurman, E.T, Murakami, K.S. Deposit date: 2015-02-25 Release date: 2015-03-11 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.844 Å) Cite: X-ray Crystal Structures of Escherichia coli RNA Polymerase with Switch Region Binding Inhibitors Enable Rational Design of Squaramides with an Improved Fraction Unbound to Human Plasma Protein. J.Med.Chem., 58, 2015
4YFK	Escherichia coli RNA polymerase in complex with squaramide compound 8. Descriptor: 3,5-dimethyl-N-{2-[4-(4-methylbenzyl)piperidin-1-yl]-3,4-dioxocyclobut-1-en-1-yl}-1,2-oxazole-4-sulfonamide, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... Authors: Molodtsov, V, Fleming, P.R, Eyermann, C.J, Ferguson, A.D, Foulk, M.A, McKinney, D.C, Masse, C.E, Buurman, E.T, Murakami, K.S. Deposit date: 2015-02-25 Release date: 2015-03-11 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.571 Å) Cite: X-ray Crystal Structures of Escherichia coli RNA Polymerase with Switch Region Binding Inhibitors Enable Rational Design of Squaramides with an Improved Fraction Unbound to Human Plasma Protein. J.Med.Chem., 58, 2015
5HKC	Crystal structure of M. tuberculosis MazF-mt3 T52D-F62D mutant in complex with 8-mer RNA Descriptor: Endoribonuclease MazF6, RNA (5'-R(*GP*UP*C)-D(P*U)-R(P*CP*CP*UP*A)-3') Authors: Yen, T.J, Brennan, R.G. Deposit date: 2016-01-14 Release date: 2017-01-18 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.68 Å) Cite: Crystal structure of M. tuberculosis MazF-mt3 T52D-F62D mutant in complex with 8-mer RNA To Be Published
4YFN	Escherichia coli RNA polymerase in complex with squaramide compound 14 (N-[3,4-dioxo-2-(4-{[4-(trifluoromethyl)benzyl]amino}piperidin-1-yl)cyclobut-1-en-1-yl]-3,5-dimethyl-1,2-oxazole-4-sulfonamide) Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... Authors: Molodtsov, V, Fleming, P.R, Eyermann, C.J, Ferguson, A.D, Foulk, M.A, McKinney, D.C, Masse, C.E, Buurman, E.T, Murakami, K.S. Deposit date: 2015-02-25 Release date: 2015-03-11 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.817 Å) Cite: X-ray Crystal Structures of Escherichia coli RNA Polymerase with Switch Region Binding Inhibitors Enable Rational Design of Squaramides with an Improved Fraction Unbound to Human Plasma Protein. J.Med.Chem., 58, 2015
4J6X	Crystal structure of Hfq from Pseudomonas aeruginosa in complex with UTP Descriptor: Protein hfq, URIDINE 5'-TRIPHOSPHATE Authors: Nikulin, A.D, Murina, V, Lekontseva, N. Deposit date: 2013-02-12 Release date: 2013-07-31 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.222 Å) Cite: Hfq binds ribonucleotides in three different RNA-binding sites. Acta Crystallogr.,Sect.D, 69, 2013
4J6Y	Hfq from Pseudomonas aeruginosa crystallized in GTP presence Descriptor: CADMIUM ION, Protein hfq Authors: Nikulin, A.D, Murina, V, Lekontseva, N. Deposit date: 2013-02-12 Release date: 2013-07-31 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.1405 Å) Cite: Hfq binds ribonucleotides in three different RNA-binding sites. Acta Crystallogr.,Sect.D, 69, 2013
4J6W	Crystal structure of HFQ from Pseudomonas aeruginosa in complex with CTP Descriptor: CHLORIDE ION, CYTIDINE-5'-DIPHOSPHATE, CYTIDINE-5'-MONOPHOSPHATE, ... Authors: Nikulin, A.D, Murina, V, Lekontseva, N. Deposit date: 2013-02-12 Release date: 2013-07-31 Last modified: 2024-07-03 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Hfq binds ribonucleotides in three different RNA-binding sites. Acta Crystallogr.,Sect.D, 69, 2013
3OIN	Crystal structure of Saccharomyces cerevisiae Nep1/Emg1 bound to S-adenosylhomocysteine and 1 molecule of cognate RNA Descriptor: 5'-R(*GP*GP*GP*CP*UP*UP*CP*AP*AP*CP*GP*CP*CP*C)-3', CHLORIDE ION, GLYCEROL, ... Authors: Thomas, S.R, LaRonde-LeBlanc, N. Deposit date: 2010-08-19 Release date: 2010-12-01 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural insight into the functional mechanism of Nep1/Emg1 N1-specific pseudouridine methyltransferase in ribosome biogenesis. Nucleic Acids Res., 39, 2011
3Q0L	Crystal structure of the PUMILIO-homology domain from Human PUMILIO1 in complex with p38alpha NREa Descriptor: 5'-R(UP*GP*UP*AP*AP*AP*UP*A)-3', Pumilio homolog 1 Authors: Lu, G, Hall, T.M.T. Deposit date: 2010-12-15 Release date: 2011-03-16 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.503 Å) Cite: Alternate modes of cognate RNA recognition by human PUMILIO proteins. Structure, 19, 2011
3Q0M	Crystal structure of the PUMILIO-homology domain from Human PUMILIO1 in complex with p38alpha NREb Descriptor: 5'-R(UP*GP*UP*AP*GP*AP*UP*A)-3', Pumilio homolog 1 Authors: Lu, G, Hall, T.M.T. Deposit date: 2010-12-15 Release date: 2011-03-16 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2.705 Å) Cite: Alternate modes of cognate RNA recognition by human PUMILIO proteins. Structure, 19, 2011
5ZUU	Crystal structure of AtCPSF30 YTH domain in complex with 10mer m6A-modified RNA Descriptor: 30-kDa cleavage and polyadenylation specificity factor 30, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ... Authors: Wu, B, Nie, H, Li, S, Patel, D.J. Deposit date: 2018-05-08 Release date: 2019-05-15 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.95 Å) Cite: CPSF30-L-mediated recognition of mRNA m6A modification controls alternative polyadenylation of nitrate signaling-related gene transcripts in Arabidopsis. Mol Plant, 2021
7A9W	Structure of yeast Rmd9p in complex with 20nt target RNA Descriptor: CHLORIDE ION, Protein RMD9, mitochondrial, ... Authors: Hillen, H.S, Markov, D.A, Ireneusz, W.D, Hofmann, K.B, Cowan, A.T, Jones, J.L, Temiakov, D, Cramer, P, Anikin, M. Deposit date: 2020-09-02 Release date: 2021-04-07 Last modified: 2021-05-05 Method: X-RAY DIFFRACTION (2.55 Å) Cite: The pentatricopeptide repeat protein Rmd9 recognizes the dodecameric element in the 3'-UTRs of yeast mitochondrial mRNAs. Proc.Natl.Acad.Sci.USA, 118, 2021
7A9X	Structure of yeast Rmd9p in complex with 16nt target RNA Descriptor: CHLORIDE ION, Protein RMD9, mitochondrial, ... Authors: Hillen, H.S, Markov, D.A, Ireneusz, W.D, Hofmann, K.B, Cowan, A.T, Jones, J.L, Temiakov, D, Cramer, P, Anikin, M. Deposit date: 2020-09-02 Release date: 2021-04-07 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.45 Å) Cite: The pentatricopeptide repeat protein Rmd9 recognizes the dodecameric element in the 3'-UTRs of yeast mitochondrial mRNAs. Proc.Natl.Acad.Sci.USA, 118, 2021
6E5U	Crystal structure of the mRNA export receptor NXF1/NXT1 in complex with influenza virus NS1 protein Descriptor: NTF2-related export protein 1, Non-structural protein 1, Nuclear RNA export factor 1 Authors: Xie, Y, Ren, Y. Deposit date: 2018-07-23 Release date: 2019-04-24 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.8 Å) Cite: Structural basis for influenza virus NS1 protein block of mRNA nuclear export. Nat Microbiol, 4, 2019
5EN1	Crystal structure of hnRNPA2B1 in complex with RNA Descriptor: Heterogeneous nuclear ribonucleoproteins A2/B1, RNA (5'-R(*AP*GP*GP*AP*CP*UP*G)-3') Authors: Wu, B.X, Su, S.C, Ma, J.B. Deposit date: 2015-11-09 Release date: 2016-11-09 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.58 Å) Cite: Molecular basis for the specific and multivariant recognitions of RNA substrates by human hnRNP A2/B1 Nat Commun, 2018
7Z5Y	CRYSTAL STRUCTURE OF WEISSELLA VIRIDESCENS FEMXVV NON-RIBOSOMAL AMINO ACID TRANSFERASE IN COMPLEX WITH A PEPTIDYL-XNA CONJUGATE Descriptor: GLYCEROL, HNA (5'-D(P*(6HA)P*(6HC)P*(6HC))-R(P*(A9Z))-3'), N-acetyl-alpha-muramic acid, ... Authors: Li de la Sierra-Gallay, I. Deposit date: 2022-03-10 Release date: 2022-10-26 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.71 Å) Cite: Amino-acyl tXNA as inhibitors or amino acid donors in peptide synthesis. Nucleic Acids Res., 50, 2022
5AXM	Crystal structure of Thg1 like protein (TLP) with tRNA(Phe) Descriptor: MAGNESIUM ION, RNA (75-MER), tRNA(His)-5'-guanylyltransferase (Thg1) like protein Authors: Kimura, S, Suzuki, T, Yu, J, Kato, K, Yao, M. Deposit date: 2015-07-31 Release date: 2016-08-03 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.21 Å) Cite: Template-dependent nucleotide addition in the reverse (3'-5') direction by Thg1-like protein Sci Adv, 2, 2016
5F6C	The structure of E. coli RNase E catalytically inactive mutant with RNA bound Descriptor: MAGNESIUM ION, RNA (5'-R(P*GP*U)-3'), RNA (5'-R(P*GP*UP*G)-3'), ... Authors: Bandyra, K.J, Luisi, B.F. Deposit date: 2015-12-05 Release date: 2016-12-14 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (3.002 Å) Cite: Substrate Recognition and Autoinhibition in the Central Ribonuclease RNase E. Mol. Cell, 72, 2018
5AXN	Crystal structure of Thg1 like protein (TLP) with tRNA(Phe) and GDPNP Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, RNA (75-MER), ... Authors: Kimura, S, Suzuki, T, Yu, J, Kato, K, Yao, M. Deposit date: 2015-07-31 Release date: 2016-08-03 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.703 Å) Cite: Template-dependent nucleotide addition in the reverse (3'-5') direction by Thg1-like protein Sci Adv, 2, 2016
7K9B	Crystal structure of Bacillus halodurans OapB (native) at 1.2 A Descriptor: CHLORIDE ION, OLE-associated protein B Authors: Yang, Y, Breaker, R.R. Deposit date: 2020-09-29 Release date: 2021-03-03 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.202 Å) Cite: Structure of a bacterial OapB protein with its OLE RNA target gives insights into the architecture of the OLE ribonucleoprotein complex. Proc.Natl.Acad.Sci.USA, 118, 2021
7K9C	Crystal structure of Bacillus halodurans OapB (iodine-derivative) at 1.0 A Descriptor: IODIDE ION, OLE-associated protein B Authors: Yang, Y, Breaker, R.R. Deposit date: 2020-09-29 Release date: 2021-03-03 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1 Å) Cite: Structure of a bacterial OapB protein with its OLE RNA target gives insights into the architecture of the OLE ribonucleoprotein complex. Proc.Natl.Acad.Sci.USA, 118, 2021
7AST	Apo Human RNA Polymerase III Descriptor: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... Authors: Ramsay, E.P, Abascal-Palacios, G, Daiss, J.L, King, H, Gouge, J, Pilsl, M, Beuron, F, Morris, E, Gunkel, P, Engel, C, Vannini, A. Deposit date: 2020-10-28 Release date: 2020-12-23 Last modified: 2020-12-30 Method: ELECTRON MICROSCOPY (4 Å) Cite: Structure of human RNA polymerase III. Nat Commun, 11, 2020
5F8J	Enterovirus 71 Polymerase Elongation Complex (C1S4 Form) Descriptor: GLYCEROL, Genome polyprotein, MAGNESIUM ION, ... Authors: Shu, B, Gong, P. Deposit date: 2015-12-09 Release date: 2016-06-22 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.675 Å) Cite: Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation Proc.Natl.Acad.Sci.USA, 113, 2016

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