8U4P
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8U4O
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8U4S
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8U4Q
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7BST
| EcoR124I-Ocr in the Intermediate State | Descriptor: | Overcome classical restriction gp0.3, Type I restriction enzyme EcoR124II M protein, Type I restriction enzyme R Protein, ... | Authors: | Gao, Y, Gao, P. | Deposit date: | 2020-03-31 | Release date: | 2020-05-27 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.37 Å) | Cite: | Structural insights into assembly, operation and inhibition of a type I restriction-modification system. Nat Microbiol, 5, 2020
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7BTR
| EcoR124I-ArdA in the Restriction-Alleviation State | Descriptor: | Antirestriction protein ArdA, Type I restriction enzyme EcoR124II M protein, Type I restriction enzyme R Protein, ... | Authors: | Gao, Y, Gao, P. | Deposit date: | 2020-04-02 | Release date: | 2020-05-27 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.54 Å) | Cite: | Structural insights into assembly, operation and inhibition of a type I restriction-modification system. Nat Microbiol, 5, 2020
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7DVQ
| Cryo-EM Structure of the Activated Human Minor Spliceosome (minor Bact Complex) | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, 5'-O-[(S)-hydroxy{[(R)-hydroxy{[(S)-hydroxy(methoxy)phosphoryl]oxy}phosphoryl]oxy}phosphoryl]guanosine, Armadillo repeat-containing protein 7, ... | Authors: | Bai, R, Wan, R, Wang, L, Xu, K, Zhang, Q, Lei, J, Shi, Y. | Deposit date: | 2021-01-14 | Release date: | 2021-03-31 | Method: | ELECTRON MICROSCOPY (2.89 Å) | Cite: | Structure of the activated human minor spliceosome. Science, 371, 2021
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7EDX
| p53-bound TFIID-based core PIC on HDM2 promoter | Descriptor: | DNA (84-mer), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | Authors: | Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y. | Deposit date: | 2021-03-17 | Release date: | 2021-05-05 | Last modified: | 2021-05-19 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EGB
| TFIID-based holo PIC on SCP promoter | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | Authors: | Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-05 | Last modified: | 2023-07-26 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EG7
| TFIID-based core PIC on SCP promoter | Descriptor: | DNA (79-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | Authors: | Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-05 | Last modified: | 2021-05-19 | Method: | ELECTRON MICROSCOPY (6.2 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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8WAP
| Structure of transcribing complex 6 (TC6), the initially transcribing complex with Pol II positioned 6nt downstream of TSS. | Descriptor: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | Authors: | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | Deposit date: | 2023-09-08 | Release date: | 2023-12-06 | Last modified: | 2024-01-03 | Method: | ELECTRON MICROSCOPY (5.85 Å) | Cite: | Structural visualization of transcription initiation in action. Science, 382, 2023
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8WAS
| Structure of transcribing complex 9 (TC9), the initially transcribing complex with Pol II positioned 9nt downstream of TSS. | Descriptor: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | Authors: | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | Deposit date: | 2023-09-08 | Release date: | 2023-12-06 | Last modified: | 2024-01-03 | Method: | ELECTRON MICROSCOPY (6.13 Å) | Cite: | Structural visualization of transcription initiation in action. Science, 382, 2023
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7EG9
| TFIID-based intermediate PIC on SCP promoter | Descriptor: | DNA (79-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | Authors: | Chen, X, Qi, Y, Wang, X, Wu, Z, Li, J, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-05 | Last modified: | 2021-05-19 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EGA
| TFIID-based intermediate PIC on PUMA promoter | Descriptor: | DNA (85-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | Authors: | Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-05 | Last modified: | 2021-05-19 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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8WAN
| Structure of transcribing complex 4 (TC4), the initially transcribing complex with Pol II positioned 4nt downstream of TSS. | Descriptor: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | Authors: | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | Deposit date: | 2023-09-07 | Release date: | 2023-12-06 | Last modified: | 2024-01-03 | Method: | ELECTRON MICROSCOPY (6.07 Å) | Cite: | Structural visualization of transcription initiation in action. Science, 382, 2023
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7EGH
| TFIID lobe C subcomplex | Descriptor: | DNA (45-MER), Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 2, ... | Authors: | Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-12 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EGI
| TFIID in rearranged conformation | Descriptor: | TATA-box-binding protein, Transcription initiation factor IIA subunit 1, Transcription initiation factor IIA subunit 2, ... | Authors: | Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-12 | Method: | ELECTRON MICROSCOPY (9.82 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EG8
| TFIID-based core PIC on PUMA promoter | Descriptor: | DNA (85-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... | Authors: | Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-05 | Last modified: | 2021-05-19 | Method: | ELECTRON MICROSCOPY (7.4 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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8WAL
| Structure of transcribing complex 3 (TC3), the initially transcribing complex with Pol II positioned 3nt downstream of TSS. | Descriptor: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | Authors: | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | Deposit date: | 2023-09-07 | Release date: | 2023-12-06 | Last modified: | 2024-01-03 | Method: | ELECTRON MICROSCOPY (8.52 Å) | Cite: | Structural visualization of transcription initiation in action. Science, 382, 2023
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7EGD
| SCP promoter-bound TFIID-TFIIA in initial TBP-loading state | Descriptor: | DNA (72-MER), TATA-box-binding protein, Transcription initiation factor IIA subunit 1, ... | Authors: | Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-12 | Method: | ELECTRON MICROSCOPY (6.75 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EGJ
| SCP promoter-bound TFIID-TFIIA in post TBP-loading state | Descriptor: | DNA (74-MER), TATA-box-binding protein, Transcription initiation factor IIA subunit 1, ... | Authors: | Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-12 | Method: | ELECTRON MICROSCOPY (8.64 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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8WAO
| Structure of transcribing complex 5 (TC5), the initially transcribing complex with Pol II positioned 5nt downstream of TSS. | Descriptor: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | Authors: | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | Deposit date: | 2023-09-07 | Release date: | 2023-12-06 | Last modified: | 2024-01-03 | Method: | ELECTRON MICROSCOPY (6.4 Å) | Cite: | Structural visualization of transcription initiation in action. Science, 382, 2023
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8WAQ
| Structure of transcribing complex 7 (TC7), the initially transcribing complex with Pol II positioned 7nt downstream of TSS. | Descriptor: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | Authors: | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | Deposit date: | 2023-09-08 | Release date: | 2023-12-06 | Last modified: | 2024-01-03 | Method: | ELECTRON MICROSCOPY (6.29 Å) | Cite: | Structural visualization of transcription initiation in action. Science, 382, 2023
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7EGE
| TFIID in canonical conformation | Descriptor: | TATA-box-binding protein, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 10, ... | Authors: | Chen, X, Wu, Z, Li, J, Zhao, D, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-12 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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7EGC
| p53-bound TFIID-based holo PIC on HDM2 promoter | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | Authors: | Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y. | Deposit date: | 2021-03-24 | Release date: | 2021-05-12 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
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