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6I7A
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BU of 6i7a by Molmil
Co-crystal structure of human SPOP MATH domain (D140N) and human BRD3 fragment
Descriptor: Bromodomain-containing protein 3, Speckle-type POZ protein
Authors:Ostertag, M.S, Popowicz, G.M, Sattler, M.
Deposit date:2018-11-16
Release date:2019-05-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Insights into BET Client Recognition of Endometrial and Prostate Cancer-Associated SPOP Mutants.
J.Mol.Biol., 431, 2019
2CR2
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BU of 2cr2 by Molmil
Solution structure of N-terminal domain of speckle-type POZ protein
Descriptor: Speckle-type POZ protein
Authors:Nagashima, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-20
Release date:2005-11-20
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of N-terminal domain of speckle-type POZ protein
To be Published
2F1W
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BU of 2f1w by Molmil
Crystal structure of the TRAF-like domain of HAUSP/USP7
Descriptor: CALCIUM ION, Ubiquitin carboxyl-terminal hydrolase 7
Authors:Hu, M, Gu, L, Jeffrey, P.D, Shi, Y.
Deposit date:2005-11-15
Release date:2006-02-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural Basis of Competitive Recognition of p53 and MDM2 by HAUSP/USP7: Implications for the Regulation of the p53-MDM2 Pathway.
Plos Biol., 4, 2006
2F1Y
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BU of 2f1y by Molmil
Crystal structure of the TRAF-like domain of HAUSP/USP7 bound to a MDM2 peptide
Descriptor: HAUSP/USP7
Authors:Hu, M, Gu, L, Jeffrey, P.D, Shi, Y.
Deposit date:2005-11-15
Release date:2006-02-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Basis of Competitive Recognition of p53 and MDM2 by HAUSP/USP7: Implications for the Regulation of the p53-MDM2 Pathway.
Plos Biol., 4, 2006
2F1X
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BU of 2f1x by Molmil
Crystal structure of the TRAF-like domain of HAUSP/USP7 bound to a p53 peptide
Descriptor: HAUSP/USP7
Authors:Hu, M, Gu, L, Jeffrey, P.D, Shi, Y.
Deposit date:2005-11-15
Release date:2006-02-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis of Competitive Recognition of p53 and MDM2 by HAUSP/USP7: Implications for the Regulation of the p53-MDM2 Pathway.
Plos Biol., 4, 2006
3HQL
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BU of 3hql by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases:SPOPMATHx-PucSBC1_pep2
Descriptor: Puckered, SULFATE ION, Speckle-type POZ protein
Authors:Zhuang, M, Schulman, B.A.
Deposit date:2009-06-07
Release date:2009-10-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
Mol.Cell, 36, 2009
3IVQ
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BU of 3ivq by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATH-CiSBC2
Descriptor: CiSBC2, Speckle-type POZ protein
Authors:Schulman, B.A, Miller, D.J, Calabrese, M.F, Seyedin, S.
Deposit date:2009-09-01
Release date:2009-10-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases.
Mol.Cell, 36, 2009
3IVV
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BU of 3ivv by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATH-PucSBC1_pep1
Descriptor: PucSBC1, Speckle-type POZ protein
Authors:Schulman, B.A, Miller, D.J, Calabrese, M.F, Seyedin, S.
Deposit date:2009-09-01
Release date:2009-10-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases.
Mol.Cell, 36, 2009
3HQM
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BU of 3hqm by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx-CiSBC2
Descriptor: Protein cubitus interruptus, SULFATE ION, Speckle-type POZ protein
Authors:Zhuang, M, Schulman, B.A.
Deposit date:2009-06-07
Release date:2009-10-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
Mol.Cell, 36, 2009
3HSV
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BU of 3hsv by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx-MacroH2ASBCpep2
Descriptor: Core histone macro-H2A.1, SULFATE ION, Speckle-type POZ protein, ...
Authors:Zhuang, M, Schulman, B.A, Miller, D.
Deposit date:2009-06-10
Release date:2009-10-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
Mol.Cell, 36, 2009
3HQH
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BU of 3hqh by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx-MacroH2ASBCpep1
Descriptor: MacroH2A, Speckle-type POZ protein, ZINC ION
Authors:Zhuang, M, Schulman, B.A.
Deposit date:2009-06-06
Release date:2009-10-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
Mol.Cell, 36, 2009
3IVB
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BU of 3ivb by Molmil
Structures of SPOP-Substrate Complexes: Insights into Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATH-MacroH2ASBCpep1
Descriptor: CHLORIDE ION, Core histone macro-H2A.1, Speckle-type POZ protein, ...
Authors:Schulman, B.A, Miller, D.J, Calabrese, M.F, Seyedin, S.
Deposit date:2009-08-31
Release date:2009-10-20
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure 9
To be Published
8DWU
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BU of 8dwu by Molmil
SPOP W22R Form 1
Descriptor: Speckle-type POZ protein
Authors:Cuneo, M.J, Mittag, T, O'Flynn, B.
Deposit date:2022-08-02
Release date:2023-01-18
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Higher-order SPOP assembly reveals a basis for cancer mutant dysregulation.
Mol.Cell, 83, 2023
8DWV
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BU of 8dwv by Molmil
Full-length wild type SPOP
Descriptor: Speckle-type POZ protein
Authors:Cuneo, M.J, Mittag, T, O'Flynn, B, Lo, Y.H.
Deposit date:2022-08-02
Release date:2023-01-18
Last modified:2023-03-22
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Higher-order SPOP assembly reveals a basis for cancer mutant dysregulation.
Mol.Cell, 83, 2023
8DWS
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BU of 8dws by Molmil
Full-length E47K SPOP
Descriptor: Speckle-type POZ protein
Authors:Cuneo, M.J, Mittag, T, O'Flynn, B, Lo, Y.H.
Deposit date:2022-08-02
Release date:2023-01-18
Last modified:2023-03-22
Method:ELECTRON MICROSCOPY (3.73 Å)
Cite:Higher-order SPOP assembly reveals a basis for cancer mutant dysregulation.
Mol.Cell, 83, 2023
8DWT
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BU of 8dwt by Molmil
SPOP W22R Form 2
Descriptor: Speckle-type POZ protein
Authors:Cuneo, M.J, Mittag, T, O'Flynn, B, Lo, Y.H.
Deposit date:2022-08-02
Release date:2023-01-18
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Higher-order SPOP assembly reveals a basis for cancer mutant dysregulation.
Mol.Cell, 83, 2023
2F1Z
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BU of 2f1z by Molmil
Crystal structure of HAUSP
Descriptor: Ubiquitin carboxyl-terminal hydrolase 7
Authors:Hu, M, Gu, L, Jeffrey, P.D, Shi, Y.
Deposit date:2005-11-15
Release date:2006-02-07
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural Basis of Competitive Recognition of p53 and MDM2 by HAUSP/USP7: Implications for the Regulation of the p53-MDM2 Pathway.
Plos Biol., 4, 2006
3HQI
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BU of 3hqi by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx/BTB/3-box-PucSBC1
Descriptor: PucSBC1, Speckle-type POZ protein
Authors:Zhuang, M, Schulman, B.A.
Deposit date:2009-06-07
Release date:2009-10-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
Mol.Cell, 36, 2009
3HU6
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BU of 3hu6 by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx/BTB/3-box-PucSBC1
Descriptor: Puckered, Speckle-type POZ protein
Authors:Zhuang, M, Schulman, B.A.
Deposit date:2009-06-13
Release date:2009-10-20
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
Mol.Cell, 36, 2009
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