PDB: 522 resultsInfo pagesStatus searchChemie searchBIRD

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7TZK	EPS8 SH3 Domain with NleH1 PxxDY Motif Descriptor: Epidermal growth factor receptor kinase substrate 8, T3SS secreted effector NleH homolog Authors: Grishin, A.M, Cygler, M. Deposit date: 2022-02-15 Release date: 2022-07-06 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.43 Å) Cite: Targeting of microvillus protein Eps8 by the NleH effector kinases from enteropathogenic E. coli Proc.Natl.Acad.Sci.USA, 119, 2022
6SCW	SH3-subunit of chicken alpha spectrin solved by NMR Descriptor: Spectrin alpha chain, non-erythrocytic 1 isoform X11 Authors: Grohe, K, Hebrank, C, Linser, R. Deposit date: 2019-07-25 Release date: 2020-08-12 Last modified: 2024-01-31 Method: SOLUTION NMR Cite: Protein Motional Details Revealed by Complementary Structural Biology Techniques. Structure, 28, 2020
6SDF	N-terminal SH3 domain of Grb2 protein Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Growth factor receptor-bound protein 2 Authors: Bolgov, A.A, Korban, S.A, Luzik, D.A, Rogacheva, O.N, Zhemkov, V.A, Kim, M, Skrynnikov, N.R, Bezprozvanny, I.B. Deposit date: 2019-07-26 Release date: 2020-01-29 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structure of the SH3 domain of growth factor receptor-bound protein 2. Acta Crystallogr.,Sect.F, 76, 2020
7CFZ	SH3 domain of NADPH oxidase activator 1 Descriptor: NADPH oxidase activator 1 Authors: Kim, M, Park, J.H, Attri, P, Lee, W. Deposit date: 2020-06-29 Release date: 2021-07-07 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Structural modification of NADPH oxidase activator (Noxa 1) by oxidative stress: An experimental and computational study. Int.J.Biol.Macromol., 163, 2020
7Y4N	Insight into the C-terminal SH3 domain mediated binding of Drosophila Drk to Sos and Dos Descriptor: Growth factor receptor-bound protein 2 Authors: Pooppadi, M.S, Ikeya, T, Sugasawa, H, Watanabe, R, Mishima, M, Inomata, K, Ito, Y. Deposit date: 2022-06-15 Release date: 2022-08-31 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Insight into the C-terminal SH3 domain mediated binding of Drosophila Drk to Sos and Dos. Biochem.Biophys.Res.Commun., 625, 2022
6ATV	The molecular mechanisms by which NS1 of the 1918 Spanish influenza A virus hijack host protein-protein interactions Descriptor: Adapter molecule crk, proline-rich motif in IAV-NS1 Authors: Shen, Q, Zeng, D, Zhao, B, Li, P, Cho, J.H. Deposit date: 2017-08-29 Release date: 2018-08-08 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.751 Å) Cite: Molecular Mechanisms of Tight Binding through Fuzzy Interactions. Biophys. J., 114, 2018
6C4S	Human cSrc SH3 Domain in complex with Choline Kinase fragment 60-69 Descriptor: Proto-oncogene tyrosine-protein kinase Src,cSrc SH3 Domain, ZINC ION Authors: Kall, S.L, Lavie, A. Deposit date: 2018-01-12 Release date: 2019-01-23 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Molecular basis for the interaction between human choline kinase alpha and the SH3 domain of the c-Src tyrosine kinase. Sci Rep, 9, 2019
6XVN	Crystal structure of c-Src SH3 domain without ATCUN motif: monomer 1 Descriptor: Proto-oncogene tyrosine-protein kinase Src Authors: Camara-Artigas, A, Plaza-Garrido, M. Deposit date: 2020-01-22 Release date: 2020-04-22 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.7 Å) Cite: The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase. J.Biol.Inorg.Chem., 25, 2020
6XVM	Crystal structure of c-Src SH3 domain without ATCUN motif: monomer 2 Descriptor: GLYCEROL, Proto-oncogene tyrosine-protein kinase Src Authors: Camara-Artigas, A, Plaza-Garrido, M. Deposit date: 2020-01-22 Release date: 2020-04-22 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (0.9 Å) Cite: The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase. J.Biol.Inorg.Chem., 25, 2020
6XVO	Crystal structure of the intertwined dimer of the c-Src SH3 domain without ATCUN motif Descriptor: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, TRIETHYLENE GLYCOL Authors: Camara-Artigas, A, Plaza-Garrido, M. Deposit date: 2020-01-22 Release date: 2020-04-22 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.7 Å) Cite: The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase. J.Biol.Inorg.Chem., 25, 2020
6XX4	Crystal structure of the c-Src SH3 domain H122R-Q128E mutant in complex with Ni(II) at pH 7.5 co-crystallized with methyl beta-cyclodextrin Descriptor: Cyclic 2,3-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-2,6-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-3-O-methyl-alpha-D-glucopyranose, NICKEL (II) ION, Proto-oncogene tyrosine-protein kinase Src Authors: Camara-Artigas, A. Deposit date: 2020-01-26 Release date: 2020-04-22 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.05 Å) Cite: The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase. J.Biol.Inorg.Chem., 25, 2020
6XX3	Crystal structure of the c-Src SH3 domain H122R-Q128E mutant in complex with Cu(II) at pH 6.5 co-crystallized with methyl beta-cyclodextrin Descriptor: COPPER (II) ION, Cyclic 2,3-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-2,6-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-3-O-methyl-alpha-D-glucopyranose, Proto-oncogene tyrosine-protein kinase Src Authors: Camara-Artigas, A. Deposit date: 2020-01-26 Release date: 2020-04-22 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.36 Å) Cite: The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase. J.Biol.Inorg.Chem., 25, 2020
6XX5	Crystal structure of the c-Src SH3 domain H122R-Q128K mutant in complex with Ni(II) at pH 7.5 co-crystallized with methyl beta-cyclodextrin Descriptor: Cyclic 2,3-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-2,6-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-3-O-methyl-alpha-D-glucopyranose, NICKEL (II) ION, Proto-oncogene tyrosine-protein kinase Src Authors: Camara-Artigas, A. Deposit date: 2020-01-26 Release date: 2020-05-27 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.3 Å) Cite: The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase. J.Biol.Inorg.Chem., 25, 2020
6XX2	Crystal structure of the c-Src SH3 domain H122R-Q128K mutant in complex with Cu(II) at pH 7.5 co-crystallized with methyl beta-cyclodextrin Descriptor: COPPER (II) ION, Cyclic 2,3-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-2,6-di-O-methyl-alpha-D-glucopyranose-(1-4)-2-O-methyl-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-3-O-methyl-alpha-D-glucopyranose, Proto-oncogene tyrosine-protein kinase Src Authors: Camara-Artigas, A. Deposit date: 2020-01-26 Release date: 2020-04-22 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.25 Å) Cite: The effect of an engineered ATCUN motif on the structure and biophysical properties of the SH3 domain of c-Src tyrosine kinase. J.Biol.Inorg.Chem., 25, 2020
4EIK	Crystal Structure of the Human Fyn SH3 domain in complex with the synthetic peptide VSL12 Descriptor: SODIUM ION, Tyrosine-protein kinase Fyn, VSL12 peptide Authors: Camara-Artigas, A. Deposit date: 2012-04-05 Release date: 2013-04-10 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Crystallization of and selenomethionine phasing strategy for a SETMAR-DNA complex. Acta Crystallogr F Struct Biol Commun, 72, 2016
4ESR	Molecular and Structural Characterization of the SH3 Domain of AHI-1 in Regulation of Cellular Resistance of BCR-ABL+ Chronic Myeloid Leukemia Cells to Tyrosine Kinase Inhibitors Descriptor: DI(HYDROXYETHYL)ETHER, Jouberin Authors: Van Petegem, X.F, Liu, P.X, Lobo, P, Jiang, X. Deposit date: 2012-04-23 Release date: 2012-06-06 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.53 Å) Cite: Molecular and structural characterization of the SH3 domain of AHI-1 in regulation of cellular resistance of BCR-ABL(+) chronic myeloid leukemia cells to tyrosine kinase inhibitors. Proteomics, 12, 2012
4F16	Crystal Structure of the alpha spectrin SH3 domain at pH 5 Descriptor: Spectrin alpha chain, brain Authors: Camara-Artigas, A, Gavira, J.A. Deposit date: 2012-05-06 Release date: 2013-05-08 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Crystal Structure of the alpha spectrin SH3 domain at pH 5 To be Published
6EDF	Fragment of a tyrosine-protein kinase Descriptor: FYN, GLYCEROL, UNKNOWN ATOM OR ION Authors: Tempel, W, Huang, H, Sochirca, I, Liu, K, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Sidhu, S.S, Min, J, Structural Genomics Consortium (SGC) Deposit date: 2018-08-09 Release date: 2018-08-29 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Fragment of a tyrosine-protein kinase To be Published
4F17	Crystal Structure of the alpha spectrin SH3 domain at pH 9 Descriptor: Spectrin alpha chain, brain Authors: Camara-Artigas, A, Gavira, J.A. Deposit date: 2012-05-06 Release date: 2013-05-08 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Crystal Structure of the alpha spectrin SH3 domain at pH 9 To be Published
4FSS	Crystal structure of a RAS p21 protein activator (RASA1) from Homo sapiens at 2.25 A resolution Descriptor: CHLORIDE ION, GLYCEROL, PHOSPHATE ION, ... Authors: Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) Deposit date: 2012-06-27 Release date: 2012-07-18 Last modified: 2023-02-01 Method: X-RAY DIFFRACTION (2.25 Å) Cite: Crystal structure of a RAS p21 protein activator (RASA1) from Homo sapiens at 2.25 A resolution To be published
7NES	Crystal structure of the v-Src SH3 domain N117D-V124L mutant Descriptor: GLYCINE, v-Src SH3 domain Authors: Camara-Artigas, A, Salinas-Garcia, M.C. Deposit date: 2021-02-04 Release date: 2021-06-02 Last modified: 2024-05-15 Method: X-RAY DIFFRACTION (1.35 Å) Cite: The impact of oncogenic mutations of the viral Src kinase on the structure and stability of the SH3 domain. Acta Crystallogr D Struct Biol, 77, 2021
7NER	Crystal structure of the v-Src SH3 domain Q128R mutant Descriptor: SULFATE ION, TETRAETHYLENE GLYCOL, v-Src SH3 domain Authors: Camara-Artigas, A, Salinas-Garcia, M.C. Deposit date: 2021-02-04 Release date: 2021-06-02 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.55 Å) Cite: The impact of oncogenic mutations of the viral Src kinase on the structure and stability of the SH3 domain. Acta Crystallogr D Struct Biol, 77, 2021
7NZC	First SH3 domain of POSH (Plenty of SH3 Domains protein) Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, E3 ubiquitin-protein ligase SH3RF1 Authors: Palencia, A, Bessa, L.M, Jensen, M.R. Deposit date: 2021-03-23 Release date: 2021-12-22 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.111 Å) Cite: Visualizing protein breathing motions associated with aromatic ring flipping. Nature, 602, 2022
7PVX	Crystal structure of the c-Src SH3 domain mutant E93V-S94A-R95S-T96G-N112G-N113Y-T114N-E115H in complex with the synthetic peptide VSL12 Descriptor: Isoform 1 of Proto-oncogene tyrosine-protein kinase Src, VSL12 peptide Authors: Camara-Artigas, A, Salinas Garcia, M.C. Deposit date: 2021-10-05 Release date: 2022-09-14 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.43 Å) Cite: Crystal structure of the c-Src SH3 domain mutants of the specificity region in complex with polyproline peptides To be published
7PVQ	Crystal structure of the Abl SH3 domain V73E-A74S-S75R-G76T-D77E-G92N-Y93N-N94T-H95E mutant in the space group P21221 Descriptor: Tyrosine-protein kinase ABL1 Authors: Camara-Artigas, A, Salinas Garcia, M.C. Deposit date: 2021-10-05 Release date: 2022-09-14 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.55 Å) Cite: The effect of the hinge loops composition in the domain swapping of the SH3 domain To be published

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