7KRZ
 
 | | Human mitochondrial LONP1 in complex with Bortezomib | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Endogenous co-purified substrate, ... | | Authors: | Shin, M, Watson, E.R, Song, A.S, Mindrebo, J.T, Novick, S.R, Griffin, P, Wiseman, R.L, Lander, G.C. | | Deposit date: | 2020-11-20 | | Release date: | 2021-02-24 | | Last modified: | 2022-06-15 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Structures of the human LONP1 protease reveal regulatory steps involved in protease activation.
Nat Commun, 12, 2021
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8S55
 | | RNA polymerase II early elongation complex bound to TFIIE and TFIIF - state a (composite structure) | | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... | | Authors: | Zhan, Y, Grabbe, F, Oberbeckmann, E, Dienemann, C, Cramer, P. | | Deposit date: | 2024-02-22 | | Release date: | 2024-04-17 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Three-step mechanism of promoter escape by RNA polymerase II.
Mol.Cell, 84, 2024
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8S5N
 | | RNA polymerase II core initially transcribing complex with an ordered RNA of 12 nt | | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... | | Authors: | Zhan, Y, Grabbe, F, Oberbeckmann, E, Dienemann, C, Cramer, P. | | Deposit date: | 2024-02-24 | | Release date: | 2024-04-10 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Three-step mechanism of promoter escape by RNA polymerase II.
Mol.Cell, 84, 2024
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4LIL
 | | Crystal structure of the catalytic subunit of human primase bound to UTP and Mn | | Descriptor: | DNA primase small subunit, MANGANESE (II) ION, URIDINE 5'-TRIPHOSPHATE, ... | | Authors: | Vaithiyalingam, S, Eichman, B.F, Chazin, W.J. | | Deposit date: | 2013-07-02 | | Release date: | 2013-12-11 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Insights into Eukaryotic Primer Synthesis from Structures of the p48 Subunit of Human DNA Primase.
J.Mol.Biol., 426, 2014
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6SR6
 | | Crystal structure of the RAC core with a pseudo substrate bound to Ssz1 SBD | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Putative heat shock protein, ... | | Authors: | Valentin Gese, G, Lapouge, K, Kopp, J, Sinning, I. | | Deposit date: | 2019-09-05 | | Release date: | 2020-03-25 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The ribosome-associated complex RAC serves in a relay that directs nascent chains to Ssb.
Nat Commun, 11, 2020
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4LL1
 | | The structure of the TRX and TXNIP complex | | Descriptor: | Thioredoxin, Thioredoxin-interacting protein | | Authors: | Hwang, J, Kim, M.H. | | Deposit date: | 2013-07-09 | | Release date: | 2014-02-05 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The structural basis for the negative regulation of thioredoxin by thioredoxin-interacting protein
Nat Commun, 5, 2014
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5JMA
 | | Crystal structure of Mycobacterium avium SerB2 in complex with serine at catalytic (PSP) domain | | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, Phosphoserine phosphatase, ... | | Authors: | Shree, S, Dubey, S, Agrawal, A, Ramachandran, R. | | Deposit date: | 2016-04-28 | | Release date: | 2017-05-03 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.03 Å) | | Cite: | Crystal structure of Mycobacterium avium SerB2 in complex with serine at catalytic (PSP) domain
To be published
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7L7T
 | | BG505 SOSIP reconstructed from a designed nanoparticle, BG505 SOSIP-T33-31 (Component A) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP.v5.2(7S) - gp120, ... | | Authors: | Antanasijevic, A, Cannac, F, Sewall, L.M, Ward, A.B. | | Deposit date: | 2020-12-30 | | Release date: | 2021-08-04 | | Last modified: | 2021-08-25 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
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7L7U
 | | BG505 SOSIP reconstructed from a designed nanoparticle, BG505 SOSIP-T33-31 (Component B) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 SOSIP.v5.2(7S) - gp120, ... | | Authors: | Antanasijevic, A, Froes Rocha, R, Sewall, L.M, Ward, A.B. | | Deposit date: | 2020-12-30 | | Release date: | 2021-08-04 | | Last modified: | 2021-08-25 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
Nat Commun, 12, 2021
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6YA4
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6YA3
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6YAB
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6Y9U
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6YAG
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6TFJ
 | | Vip3Aa protoxin structure | | Descriptor: | Vegetative insecticidal protein | | Authors: | Nunez-Ramirez, R, Huesa, J, Bel, Y, Ferre, J, Casino, P, Arias-Palomo, E. | | Deposit date: | 2019-11-14 | | Release date: | 2020-08-12 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Molecular architecture and activation of the insecticidal protein Vip3Aa from Bacillus thuringiensis.
Nat Commun, 11, 2020
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4L8B
 | | Crystal structure of the H2Db in complex with the NP-N5H peptide | | Descriptor: | Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, H-2 class I histocompatibility antigen, ... | | Authors: | Rossjohn, J, Gras, S. | | Deposit date: | 2013-06-16 | | Release date: | 2013-10-16 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Acute emergence and reversion of influenza A virus quasispecies within CD8(+) T cell antigenic peptides.
Nat Commun, 4, 2013
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7QAZ
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4NXF
 | | Crystal structure of iLOV-I486(2LT) at pH 8.0 | | Descriptor: | FLAVIN MONONUCLEOTIDE, Phototropin-2 | | Authors: | Wang, J, Liu, X, Li, J. | | Deposit date: | 2013-12-09 | | Release date: | 2014-09-24 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.766 Å) | | Cite: | Significant expansion of fluorescent protein sensing ability through the genetic incorporation of superior photo-induced electron-transfer quenchers.
J.Am.Chem.Soc., 136, 2014
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6T64
 | | A model of the EIAV CA-SP hexamer (C6) from Gag-deltaMA spheres assembled at pH6 | | Descriptor: | Gag polyprotein | | Authors: | Dick, R.A, Xu, C, Morado, D.R, Kravchuk, V, Ricana, C.L, Lyddon, T.D, Broad, A.M, Feathers, J.R, Johnson, M.C, Vogt, V.M, Perilla, J.R, Briggs, J.A.G, Schur, F.K.M. | | Deposit date: | 2019-10-17 | | Release date: | 2020-01-15 | | Last modified: | 2022-03-30 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly.
Plos Pathog., 16, 2020
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7KVT
 | | Crystal structure of Squash RNA aptamer in complex with DFHBI-1T with iridium (III) ions | | Descriptor: | (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2-methyl-3-(2,2,2-trifluoroethyl)-3,5-dihydro-4H-imidazol-4-one, IRIDIUM HEXAMMINE ION, MAGNESIUM ION, ... | | Authors: | Truong, L, Ferre-D'Amare, A.R. | | Deposit date: | 2020-11-28 | | Release date: | 2022-01-19 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.73 Å) | | Cite: | The fluorescent aptamer Squash extensively repurposes the adenine riboswitch fold.
Nat.Chem.Biol., 18, 2022
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7KVV
 | | Crystal structure of Squash RNA aptamer in complex with DFHBI-1T | | Descriptor: | (5Z)-5-[(3,5-difluoro-4-hydroxyphenyl)methylidene]-2-[(E)-(hydroxyimino)methyl]-3-methyl-3,5-dihydro-4H-imidazol-4-one, MAGNESIUM ION, Squash RNA aptamer bound to DFHO | | Authors: | Truong, L, Ferre-D'Amare, A.R. | | Deposit date: | 2020-11-28 | | Release date: | 2022-01-19 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | The fluorescent aptamer Squash extensively repurposes the adenine riboswitch fold.
Nat.Chem.Biol., 18, 2022
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7KVU
 | | Crystal structure of Squash RNA aptamer in complex with DFHBI-1T | | Descriptor: | (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2-methyl-3-(2,2,2-trifluoroethyl)-3,5-dihydro-4H-imidazol-4-one, MAGNESIUM ION, POTASSIUM ION, ... | | Authors: | Truong, L, Ferre-D'Amare, A.R. | | Deposit date: | 2020-11-28 | | Release date: | 2022-01-19 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.68 Å) | | Cite: | The fluorescent aptamer Squash extensively repurposes the adenine riboswitch fold.
Nat.Chem.Biol., 18, 2022
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6TF9
 | | Structure of the vertebrate gamma-Tubulin Ring Complex | | Descriptor: | Actin, cytoplasmic 1, Belt helices 1,2,3,4, ... | | Authors: | Zupa, E, Pfeffer, S. | | Deposit date: | 2019-11-13 | | Release date: | 2019-12-11 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (4.8 Å) | | Cite: | Insights into the assembly and activation of the microtubule nucleator gamma-TuRC.
Nature, 578, 2020
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5O5W
 | | Molybdenum storage protein room-temperature structure determined by serial millisecond crystallography | | Descriptor: | (mu3-oxo)-tris(mu2-oxo)-nonakisoxo-trimolybdenum (VI), ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Steffen, B, Weinert, T, Ermler, U, Standfuss, J. | | Deposit date: | 2017-06-02 | | Release date: | 2017-09-27 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons.
Nat Commun, 8, 2017
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4M1M
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